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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PGDRQWYSFLASSLVTFGSGLVVIIIYRIVLWLCCDWAGELISGQTTTGRILVGLVFLLSIASLIIYFIDASTNTSSTTQ
QVDLAFNVFFMIYFFIRFVAANDKLWFWVELFSFVDYFTIPPSFVAIYLDRNWLGLRFLRALRLMSIPDILTYLNVLKTS
TLIRLVQLVVSFVSLWLTAAGFLHLLENSGDPFFDFGNAQHLTYWECLYFLMVTMSTVGFGDIFATTVLGRTFVVIFIMI
FIGLFASFIPEIAEILGKRQKYGGSYKKERGKRHVVVCGYITFDSVSNFLKDFLHKDREDVDVEIVFLHKGLPGLELEGL
LKRHFTQVEYFWGSVMDANDLERVKIQEADACLVLANKYCQDPDQEDAANIMRVISIKNYHSDIKVIVQLLQYHNKAYLL
NIPSWDWKRGDDAVCVAELKLGFIAQSCLAPGFSTLMANLFTMRSYKPTPEMSQWQTDYMRGTGMEMYTEYLSSAFNALT
FPEAAELCFSKLKLLLLAIEVRQEDTRESTLAINPGPKVKIENATQGFFIAESAEEVKRAFYYCKNCHANVSDVRQIKKC
KCRPEPRKFDSTGMFHWCPDRPLNDCLQDRSQASASGLRNHVVVCLFADAASPLIGLRNLVMPLRASNFHYHELKPTIIV
GNLDYLHREWKTLQNFPKLSILPGSPLNRANLRAVNINLCDMCVIVSAKDRNMEDPNLVDKEAILCSLNIKAMTFDDAGA
NVPLITELANDSNVQFLDQDDDDDPDTELYMTQPFACGTAFAVSVLDSLMSTSYFNDNALTLIRTLITGGATPELEQILA
EGAGMRGGYCSPAVLANRDRCRVAQISLFDGPLAQFGQGGHYGELFVYALRHFGILCIGLYRFRDTNESVRSPSSKRYVI
TNPPEDFPLLPTDQVYVLTYKQ

The query sequence (length=902) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7rjt:A 902 902 1.0000 1.0000 1.0000 0.0 7rjt:B, 7rjt:C, 7rjt:D, 7rk6:A, 7rk6:B, 7rk6:C, 7rk6:D, 5tj6:A
2 7pxe:A 885 909 0.6984 0.7119 0.6931 0.0 7pxe:B, 7pxe:C, 7pxe:D, 7pxf:A, 7pxf:B, 7pxf:C, 7pxf:D, 7pxg:A, 7pxg:B, 7pxg:C, 7pxg:D, 7pxh:A, 7pxh:B, 7pxh:C, 7pxh:D
3 6v35:A 914 911 0.6463 0.6379 0.6400 0.0 6v35:D, 6v35:B, 6v35:C, 8z3s:A, 8z3s:B, 8z3s:C, 8z3s:D
4 8ghf:A 910 916 0.6341 0.6286 0.6245 0.0 8ghf:B, 8ghf:C, 8ghf:D, 3mt5:A, 8s3e:A, 8s3e:B, 8s3e:C, 8s3e:D, 3u6n:A, 3u6n:B, 3u6n:C, 3u6n:D, 3u6n:E, 3u6n:F, 3u6n:G, 3u6n:H, 6v22:A, 6v22:B, 6v22:C, 6v22:D, 6v38:A, 6v38:B, 6v38:C, 6v38:D, 6v5a:A, 7ynz:A, 7ynz:C, 7ynz:E, 7ynz:G, 7yo0:A, 7yo0:C, 7yo0:E, 7yo0:G, 7yo1:A, 7yo1:C, 7yo1:E, 7yo1:G, 7yo3:A, 7yo5:A, 7yo5:B, 7yo5:C, 7yo5:D
5 8hir:A 918 786 0.2084 0.2048 0.2392 6.40e-47 8hir:B, 8hir:C, 8hir:D, 8hk6:A, 8hk6:B, 8hk6:C, 8hk6:D, 8hkf:A, 8hkf:B, 8hkf:C, 8hkf:D, 8hkk:A, 8hkk:B, 8hkk:C, 8hkk:D, 8hkm:A, 8hkm:B, 8hkm:C, 8hkm:D, 8hkq:D, 8hkq:A, 8hkq:C, 8hkq:B
6 6oly:C 318 211 0.0588 0.1667 0.2512 2.35e-07 2aef:A, 2aef:B, 5bkj:A, 5bkj:C, 5bkj:E, 5bkj:G, 5bkk:A, 5bkk:C, 5bkk:G, 8fz7:A, 8fz7:C, 8fz7:E, 8fz7:G, 3kxd:A, 3kxd:B, 4l73:A, 4l73:B, 4l74:A, 4l74:B, 4l75:A, 4l75:B, 4l75:C, 4l75:D, 4l75:E, 4l75:F, 4l76:A, 4l76:B, 4l76:C, 4l76:D, 4l76:E, 4l76:F, 1lnq:A, 1lnq:B, 1lnq:C, 1lnq:D, 1lnq:E, 1lnq:F, 1lnq:G, 1lnq:H, 6oly:A, 6oly:B, 6oly:D, 3rbx:A, 3rbx:B, 3rbx:C, 3rbx:D, 3rbx:E, 3rbx:F, 6u5n:A, 6u5n:E, 6u5n:B, 6u5n:F, 6u5n:C, 6u5n:G, 6u5n:D, 6u5n:H, 6u5p:A, 6u5p:E, 6u5p:B, 6u5p:F, 6u5p:C, 6u5p:G, 6u5p:D, 6u5p:H, 6u5r:A, 6u5r:B, 6u5r:C, 6u5r:D, 6u5r:E, 6u5r:F, 6u5r:G, 6u5r:H, 6uwn:A, 6uwn:E, 6uwn:B, 6uwn:F, 6uwn:C, 6uwn:G, 6uwn:D, 6uwn:H, 6ux4:A, 6ux4:E, 6ux4:B, 6ux4:F, 6ux4:C, 6ux4:G, 6ux4:D, 6ux4:H
7 8ctn:B 96 48 0.0233 0.2188 0.4375 3.97e-06 8cts:B, 8ctu:B, 8cu2:B, 8cu3:B, 8cu4:B, 6dz1:B, 6fiz:C, 6fiz:D, 6fiz:E, 6fiz:G, 6fiz:H, 6fiz:J, 6fiz:L, 6fiz:N, 6fiz:A, 6fiz:O, 6fiz:P, 4r50:B, 4r6z:A, 4r6z:B, 4r7c:C, 4r8c:A, 4ro2:A, 4ro2:B, 4ro2:D
8 5wie:B 390 154 0.0432 0.1000 0.2532 1.04e-05 4jta:B, 4jtc:B, 4jtd:B, 3lnm:B, 2r9r:B
9 4jta:Q 363 154 0.0432 0.1074 0.2532 2.74e-05 4jtc:H, 4jtd:H, 2r9r:H
10 3rbz:A 289 190 0.0477 0.1488 0.2263 9.33e-05 3rbz:B, 3rbz:C, 3rbz:D
11 4uuj:C 111 89 0.0299 0.2432 0.3034 1.03e-04 2bob:C, 2dwd:C, 2dwe:C, 2h8p:C, 2h8p:D, 2hfe:C, 2hfe:D, 2hg5:C, 2hg5:D, 2hvj:C, 3ifx:A, 3ifx:B, 3ifx:C, 3ifx:D, 2jk5:C, 7m2h:C, 7m2h:F, 3stz:C, 8thn:C, 2w0f:C
12 8x43:A 327 217 0.0610 0.1682 0.2535 8.42e-04 8j00:A, 8j00:B, 8j00:C, 8j00:D, 8x43:G, 8x43:C, 8x43:E
13 7xnk:A 348 223 0.0599 0.1552 0.2422 8.73e-04 7tci:A, 7tci:G, 7tci:E, 7tci:C, 4umo:A, 6v01:A, 6v01:J, 6v01:D, 6v01:G, 7xnk:C, 7xnk:E, 7xnk:G, 7xnl:A, 7xnl:C, 7xnl:E, 7xnl:G, 7xnn:B, 7xnn:G, 7xnn:C, 7xnn:E
14 7cr7:A 354 217 0.0599 0.1525 0.2488 0.002 7cr1:A, 7cr1:B, 7cr1:C, 7cr1:D, 7cr2:B, 7cr2:C, 7cr2:D, 7cr2:A, 7cr4:A, 7cr4:B, 7cr4:D, 7cr4:F, 7cr7:G, 7cr7:B, 7cr7:D, 8ijk:A, 8ijk:C, 8ijk:B, 8ijk:D, 8izy:A, 8izy:B, 8izy:D, 8izy:C, 8j01:G, 8j01:A, 8j01:B, 8j01:D, 8j02:G, 8j02:A, 8j02:B, 8j02:D, 8j03:A, 8j03:D, 8j03:G, 8j03:I, 8j04:A, 8j04:G, 8j04:B, 8j04:D, 8w4u:A, 8w4u:B, 8w4u:D, 8w4u:G
15 2q67:A 104 65 0.0266 0.2308 0.3692 0.004 2q67:B, 2q68:A, 2q68:B, 2q69:A, 2q6a:A, 2q6a:B, 4ro2:C, 6v8y:A
16 7ssy:A 346 206 0.0521 0.1358 0.2282 0.012 7ssy:B, 7ssy:C, 7ssy:D, 7wf3:B, 7wf3:D, 7wf3:F, 7wf3:H
17 7yid:A 660 80 0.0255 0.0348 0.2875 0.012 7yid:B, 7yid:C, 7yid:D
18 7e8e:D 459 201 0.0443 0.0871 0.1990 0.014 7e87:B, 7e87:A, 7e87:C, 7e87:D, 7e8e:B, 1nn7:A, 7ukg:A, 7ukg:B, 7ukg:C, 7ukg:D
19 4twk:B 241 59 0.0177 0.0664 0.2712 0.13
20 4twk:B 241 60 0.0188 0.0705 0.2833 1.0
21 8vt9:A 406 132 0.0344 0.0764 0.2348 0.46 6cjq:A, 6cjq:B, 6cjq:C, 6cjq:D, 6cjt:A, 6cjt:B, 6cjt:C, 6cjt:D, 6cju:A, 6cju:B, 6cju:C, 6cju:D, 4d7s:A, 4d7s:B, 4d7t:A, 7rsh:A, 7rsh:B, 7rsh:C, 7rsh:D, 7rtf:A, 7rtf:B, 7rtf:C, 7rtf:D, 7rtj:A, 7rtj:B, 7rtj:C, 7rtj:D, 7tj5:A, 7tj5:B, 7tj5:C, 7tj5:D, 7tj6:A, 7tj6:B, 7tj6:C, 7tj6:D, 7tkt:A, 7tkt:B, 7tkt:C, 7tkt:D, 8vt9:D, 8vt9:B, 8vt9:C, 8vta:A, 8vta:B, 8vta:C, 8vta:D, 8vtb:A, 8vtb:B, 8vtb:C, 8vtb:D, 6vxz:A, 6vxz:B, 6vxz:C, 6vxz:D
22 8qz3:B 266 80 0.0266 0.0902 0.3000 0.53 4bw5:A, 4bw5:B, 4bw5:D, 8qz2:A, 8qz2:B, 8qz3:A, 8qz4:A, 8qz4:B, 4xdj:A, 4xdj:B, 4xdj:D, 4xdk:A, 4xdk:B, 4xdl:A, 4xdl:B, 4xdl:D
23 8qz3:B 266 63 0.0177 0.0602 0.2540 1.2 4bw5:A, 4bw5:B, 4bw5:D, 8qz2:A, 8qz2:B, 8qz3:A, 8qz4:A, 8qz4:B, 4xdj:A, 4xdj:B, 4xdj:D, 4xdk:A, 4xdk:B, 4xdl:A, 4xdl:B, 4xdl:D
24 7vnr:A 333 122 0.0388 0.1051 0.2869 0.56 7vnr:C, 7vnr:E, 7vnr:G
25 7ryr:A 389 132 0.0344 0.0797 0.2348 0.56 7ru0:A, 7ru0:B, 7ru0:C, 7ru0:D, 7ryr:C, 7ryr:D, 7ryr:B, 7rys:A, 7rys:B, 7rys:C, 7rys:D
26 7byl:A 354 122 0.0388 0.0989 0.2869 0.57 7byl:C, 7byl:E, 7byl:G, 7bym:A, 7bym:C, 7bym:E, 7bym:G, 7byn:A, 7byn:C, 7byn:E, 7byn:G, 7vnp:A, 7vnp:C, 7vnp:G, 7vnp:E, 7vnq:A, 7vnq:C, 7vnq:E, 7vnq:G
27 8de8:B 276 29 0.0144 0.0471 0.4483 0.78 8de7:B, 8de7:A, 8de8:A, 8de9:A, 8de9:B
28 8de8:B 276 112 0.0344 0.1123 0.2768 1.9 8de7:B, 8de7:A, 8de8:A, 8de9:A, 8de9:B
29 6rv2:D 261 30 0.0122 0.0421 0.3667 0.83 6rv2:A, 6rv2:B, 6rv2:C, 6rv3:A, 6rv3:B, 6rv3:C, 6rv3:D, 6rv4:A, 6rv4:B, 6rv4:C, 6rv4:D
30 6v3c:B 260 63 0.0177 0.0615 0.2540 1.2 6v36:A, 6v3c:A, 6v3i:A, 6w7b:A, 6w7d:A, 6w7e:A
31 6v3c:B 260 29 0.0133 0.0462 0.4138 5.6 6v36:A, 6v3c:A, 6v3i:A, 6w7b:A, 6w7d:A, 6w7e:A
32 8qz1:A 242 75 0.0266 0.0992 0.3200 1.2 4bw5:C, 8qz1:B, 4xdj:C, 4xdk:C, 4xdk:D, 4xdl:C
33 8qz1:A 242 81 0.0244 0.0909 0.2716 2.8 4bw5:C, 8qz1:B, 4xdj:C, 4xdk:C, 4xdk:D, 4xdl:C
34 3um7:A 259 34 0.0166 0.0579 0.4412 1.3 4i9w:A, 7lj4:A, 7lj5:A, 7lja:A, 7ljb:A, 4rue:A, 4rue:B, 4ruf:A, 4ruf:B, 3um7:B, 4wfe:A, 4wff:A, 4wfg:A, 4wfh:A
35 8quc:A 395 170 0.0388 0.0886 0.2059 1.3 8f1c:A, 8f1c:B, 8f1c:C, 8f1c:D, 8f1d:A, 8f1d:B, 8f1d:C, 8f1d:D, 7phi:C, 7phi:B, 7phi:D, 8quc:B, 8quc:D, 8quc:C, 8qud:A, 8qud:B, 8qud:C, 8qud:D
36 6cq6:B 282 63 0.0177 0.0567 0.2540 1.3 6cq6:A, 6cq8:A, 6cq8:B, 6cq9:A, 6cq9:B, 4twk:A, 8ue2:A, 8ue2:B, 8ue9:A, 8ue9:B, 8uec:A, 8uec:B, 8uf6:A, 8uf6:B, 6v36:B, 6v37:A, 6v37:B, 6v3i:B, 6w7b:B, 6w7c:A, 6w7c:B, 6w7d:B, 6w7e:B, 6w82:A, 6w82:B, 6w83:A, 6w83:B, 6w84:A, 6w84:B, 6w85:A, 6w85:B, 6w86:A, 6w86:B, 6w87:A, 6w87:B, 6w88:A, 6w88:B, 6w8a:A, 6w8a:B, 6w8c:A, 6w8c:B, 6w8f:A, 6w8f:B
37 6cq6:B 282 29 0.0133 0.0426 0.4138 5.5 6cq6:A, 6cq8:A, 6cq8:B, 6cq9:A, 6cq9:B, 4twk:A, 8ue2:A, 8ue2:B, 8ue9:A, 8ue9:B, 8uec:A, 8uec:B, 8uf6:A, 8uf6:B, 6v36:B, 6v37:A, 6v37:B, 6v3i:B, 6w7b:B, 6w7c:A, 6w7c:B, 6w7d:B, 6w7e:B, 6w82:A, 6w82:B, 6w83:A, 6w83:B, 6w84:A, 6w84:B, 6w85:A, 6w85:B, 6w86:A, 6w86:B, 6w87:A, 6w87:B, 6w88:A, 6w88:B, 6w8a:A, 6w8a:B, 6w8c:A, 6w8c:B, 6w8f:A, 6w8f:B
38 4chv:D 343 92 0.0255 0.0671 0.2500 1.8 4chw:D, 3cl1:A, 3cl1:B, 3clp:A, 3clp:C, 2k0g:A, 4muv:A, 4muv:B, 1u12:A, 1u12:B, 1vp6:A, 1vp6:C
39 8bn3:C0 96 66 0.0200 0.1875 0.2727 2.3 7a1g:C, 7b7d:C, 8bqd:C, 8bqx:C, 8cah:C, 8cas:D, 8ccs:n, 8cdl:n, 8cdr:n, 8cf5:n, 8cku:n, 5dat:C0, 5dat:c0, 5dc3:C0, 5dc3:c0, 5dge:C0, 5dge:c0, 5dgf:C0, 5dgf:c0, 5dgv:C0, 5dgv:c0, 8eub:BK, 8evp:BK, 8evq:BK, 8evr:BK, 8evs:BK, 8evt:BK, 8ewb:BK, 8ewc:BK, 5fci:C0, 6gq1:AA, 6gqb:AA, 6gqv:AA, 6hhq:L, 6hhq:c0, 5i4l:C0, 5i4l:c0, 6i7o:C, 6i7o:Cb, 3j6x:10, 3j6y:10, 3j77:10, 3j78:10, 5juo:HB, 5jup:HB, 5jus:HB, 5jut:HB, 5juu:HB, 8k2d:SK, 8k82:SK, 5m1j:K2, 5mc6:C, 5mei:c0, 5mei:L, 7mpi:BK, 7mpj:BK, 7n8b:BK, 5ndg:C0, 5ndg:c0, 5ndv:C0, 5ndv:c0, 5ndw:C0, 5ndw:c0, 7nrc:SC, 7nrd:SC, 5obm:C0, 5obm:c0, 5on6:c0, 5on6:L, 7osa:eS10, 6q8y:C, 6rbe:K, 7rr5:SK, 6s47:BL, 6snt:K, 6sv4:C, 6sv4:Cb, 6sv4:Cc, 6t4q:SK, 6t7i:SK, 6t7t:SK, 6t83:Kb, 6t83:l, 5tbw:L, 5tbw:c0, 6tb3:C, 5tga:C0, 5tgm:C0, 5tgm:c0, 6tnu:C, 4u3m:C0, 4u3m:c0, 4u3n:C0, 4u3n:c0, 4u3u:C0, 4u3u:c0, 4u4n:C0, 4u4n:c0, 4u4o:C0, 4u4o:c0, 4u4q:C0, 4u4q:c0, 4u4r:C0, 4u4r:c0, 4u4u:C0, 4u4u:c0, 4u4y:C0, 4u4y:c0, 4u4z:C0, 4u4z:c0, 4u50:C0, 4u50:c0, 4u51:C0, 4u51:c0, 4u52:C0, 4u52:c0, 4u53:C0, 4u53:c0, 4u55:C0, 4u55:c0, 4u56:C0, 4u56:c0, 4u6f:C0, 4u6f:c0, 4uer:7, 4v88:AK, 4v88:CK, 4v8y:AK, 4v8z:AK, 4v92:BK, 6wdr:K, 6woo:KK, 6xiq:AA, 6xir:AA, 6z6j:SK, 6z6k:SK, 6zce:L, 7zpq:AK, 7zrs:AK, 6zu9:D, 7zuw:AK, 7zux:DK, 6zvi:s, 7zw0:sC
40 5fci:c0 96 66 0.0200 0.1875 0.2727 2.5 5fcj:C0, 5fcj:c0, 5lyb:C0, 5lyb:c0, 5tga:c0
41 6fyx:K 96 42 0.0144 0.1354 0.3095 2.6 6fyy:K, 6gsm:K, 6gsn:K, 8i7j:K, 5it7:K, 5it9:K, 3j80:K, 3j81:K, 3jam:K, 3jap:K, 8rw1:K, 8s8d:K, 8s8e:K, 8s8f:K, 8s8g:K, 8s8h:K, 8s8i:K, 8s8j:K, 6uz7:K
42 7p4a:B 207 53 0.0211 0.0918 0.3585 3.4
43 6c80:B 486 67 0.0244 0.0453 0.3284 4.0 6c80:A
44 5aa5:A 345 45 0.0166 0.0435 0.3333 4.3 5aa5:B, 5aa5:D, 5aa5:F, 5aa5:H, 5aa5:M
45 8c3a:M 98 89 0.0233 0.2143 0.2360 6.3 8c3a:CX, 8cgn:n, 8cq7:M, 8cq7:CX, 8cqw:M, 8cqw:CX, 8cre:M, 8cre:CX, 8oeq:M, 8oeq:CX, 7pzy:L, 7q08:L, 7q0f:L, 7q0p:L, 7q0r:L, 8q5i:L
46 6v1x:A 446 53 0.0177 0.0359 0.3019 6.7 6v1x:B, 6v1x:C, 6v1x:D, 6v1y:A, 6v1y:B, 6v1y:C, 6v1y:D, 6v1y:M, 6v1y:N, 6v1y:O, 6v1y:P
47 8zyq:A 166 79 0.0233 0.1265 0.2658 7.9
48 7yiu:D 153 124 0.0344 0.2026 0.2500 8.2 7cqi:A, 7cqk:A, 6m4o:A, 7yiy:D
49 5wie:H 328 126 0.0333 0.0915 0.2381 9.5 3lnm:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218