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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PEPFADEALESYFLRLSQENGFERYRIFSGSVQDWLHTTDHAAAGAFPLELSRLNIFHASRSSGLRVRALQLVDRLTDGA
PFRLLQLALCHSAISFGNHYKAVHRSGVDIPLSFIRVHQIPCCPDCLRESAYVRQCWHFKPYVGCHRHGGRLIYSCPACG
ESLNYLASESINHCQCGFDLRTPDEIQLSALAYGCSFESSNPLLAIGSLSARFGALYWYQQRYLSDHEAVRDDRALTKAI
GHFTAWPDAFWRELQQMVDDALVRQTKPLNHTDFVDVFGSVVADCRQIPMRNTGQNFILKNLIGFLTDLVARHPQCRVAN
VGDLLLSAVDAATLLSTSVEQVRRLHHEGFLPLSIRPASRNTVSPHRAVFHLRHVVELRQARMQSHH

The query sequence (length=387) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7u5d:I 387 387 1.0000 1.0000 1.0000 0.0 7u5e:I
2 6uvn:J 389 391 0.2610 0.2596 0.2583 5.07e-41 8fuk:J, 6lnd:K, 6uvn:I, 6v9p:A, 6v9q:J, 6v9q:I, 6vbw:I, 6vbw:J
3 1qc6:A 108 36 0.0336 0.1204 0.3611 0.29 1qc6:B
4 6i0d:4 384 89 0.0594 0.0599 0.2584 0.32 6i0d:E, 6i1p:E, 3i9v:4, 3iam:4, 3ias:4, 3ias:D, 3ias:M, 3ias:V, 3m9s:4, 3m9s:D, 6q8o:4, 6q8o:E, 6q8w:4, 6q8w:E, 6q8x:4, 6q8x:E, 2ybb:4
5 5zfs:B 294 58 0.0413 0.0544 0.2759 1.2 5zfs:A
6 8fcu:P 327 172 0.1137 0.1346 0.2558 1.5 8fcv:P, 8ff4:P
7 9b4h:A 1908 66 0.0594 0.0121 0.3485 3.1 9b4h:B, 8wa2:A, 8wa2:D, 8wa2:F, 8wa2:B, 8wa2:C, 8wa2:E
8 8beq:A 534 75 0.0517 0.0375 0.2667 4.6 8beq:B, 8bes:A, 8bes:B, 8bes:C, 8bes:D, 8bet:A, 8bet:B, 8bet:C, 8bet:D, 8beu:A, 8beu:B, 8beu:C, 8beu:D
9 3bb6:C 113 52 0.0439 0.1504 0.3269 5.5 3bb6:A, 3bb6:B, 3bb6:D
10 6w15:A 202 56 0.0543 0.1040 0.3750 5.5
11 7svu:X 165 37 0.0336 0.0788 0.3514 5.9 8bd4:S, 8bd4:R, 8bd4:T, 8bd5:Q, 8ea3:Q, 8ea4:Q, 7oxd:A, 8rdu:C, 8rkt:C
12 7kgn:A 462 41 0.0310 0.0260 0.2927 7.1
13 4kqq:A 520 34 0.0310 0.0231 0.3529 7.9 7ato:A, 7atw:A, 7atx:A, 7au0:A, 7au1:A, 7au8:A, 7au9:A, 7aub:A, 7auh:A, 5df7:A, 5df7:B, 5df8:A, 5df8:B, 5df9:A, 4fsf:A, 6hr6:A, 6hr9:A, 6i1e:A, 7jwl:A, 7kit:A, 4kqo:A, 4kqo:B, 4kqq:B, 4kqr:A, 4kqr:B, 4l0l:A, 3ocl:A, 3ocn:A, 7onk:A, 7onk:B, 4ool:A, 4oom:A, 3pbq:A, 3pbr:A, 3pbs:A, 3pbt:A, 6r3x:A, 6r42:A, 6un1:A, 6un3:A, 6vje:A, 6vot:A, 4wej:A, 4wek:A, 4wel:A, 6y6u:A, 6y6z:A
14 7atm:A 478 34 0.0310 0.0251 0.3529 8.0 7kiv:A, 7kiw:A, 7lc4:A, 7ly1:A, 3pbo:A
15 6ntw:A 505 62 0.0413 0.0317 0.2581 9.3

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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