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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PELPPVPEGAVMVTLKIARFNPENPDAAGWQSFRVPCLPSDRLLNLLHYVKWYLDGTLTFRRSCAHGVCGSDAMRINGVN
RLACKVLMRDMLPKNPNKQLTITIEPIRGLPVEKDLVVNMEPFFDAYRAVKPFLVTSGNPPTKERIQSPTDRARYDDTTK
CILCACCTTSCPVYWSEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCTEACPRGIQVTQAIQEV
KRALMFA

The query sequence (length=247) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6lum:K 247 247 1.0000 1.0000 1.0000 0.0 6lum:B, 6lum:Q
2 2acz:B 238 236 0.3806 0.3950 0.3983 1.97e-57 7jz2:B, 7jz2:F, 7jz2:J, 1nek:B, 1nen:B, 2wdq:B, 2wdq:F, 2wdq:J, 2wdr:B, 2wdr:F, 2wdr:J, 2wdv:B, 2wdv:F, 2wdv:J, 2wp9:B, 2wp9:F, 2wp9:J, 2ws3:B, 2ws3:F, 2ws3:J, 2wu2:B, 2wu2:F, 2wu2:J, 2wu5:B, 2wu5:F, 2wu5:J, 6wu6:B, 6wu6:F, 6wu6:J
3 1yq3:B 242 237 0.3765 0.3843 0.3924 3.09e-51 2fbw:B, 2fbw:O, 8gs8:B, 2h88:B, 2h88:O, 2h89:B, 6myo:B, 6myp:B, 6myq:B, 6myr:B, 6mys:B, 6myt:B, 6myu:B, 2wqy:B, 2wqy:O, 1yq4:B
4 4ysx:F 252 241 0.3927 0.3849 0.4025 5.50e-50 5c2t:B, 5c2t:F, 5c3j:B, 5c3j:F, 3vr8:B, 3vr8:F, 3vr9:B, 3vr9:F, 3vra:B, 3vra:F, 3vrb:B, 3vrb:F, 4ysx:B, 4ysy:B, 4ysy:F, 4ysz:B, 4ysz:F, 4yt0:B, 4yt0:F, 4ytm:B, 4ytm:F, 4ytn:B, 4ytn:F
5 3sfe:B 240 235 0.3644 0.3750 0.3830 3.56e-48 3abv:B, 3ae1:B, 3ae2:B, 3ae3:B, 3ae4:B, 3ae5:B, 3ae6:B, 3ae7:B, 3ae8:B, 3ae9:B, 3aea:B, 3aeb:B, 3aec:B, 3aed:B, 3aee:B, 3aef:B, 3aeg:B, 7kcm:C, 3sfd:B, 4ytp:B, 4yxd:B, 1zoy:B, 1zp0:B
6 2b76:B 243 232 0.3360 0.3416 0.3578 1.68e-47 6awf:B, 6awf:F, 2b76:N, 3cir:B, 3cir:N, 1kf6:B, 1kf6:N, 1kfy:B, 1kfy:N, 4kx6:B, 4kx6:N, 1l0v:B, 1l0v:N, 3p4p:B, 3p4p:N, 3p4q:B, 3p4q:N, 3p4r:B, 3p4r:N, 3p4s:B, 3p4s:N, 5vpn:B, 5vpn:F
7 8b6g:CB 285 230 0.3320 0.2877 0.3565 3.97e-37 8bqs:CB, 8gym:sb, 8gym:SB, 8gzu:sb, 8gzu:SB
8 2bs2:B 239 240 0.2429 0.2510 0.2500 1.78e-23 2bs2:E, 2bs3:B, 2bs3:E, 2bs4:B, 2bs4:E, 1e7p:B, 1e7p:E, 1e7p:H, 1e7p:K, 1qlb:B, 1qlb:E
9 5xmj:B 240 239 0.2794 0.2875 0.2887 7.18e-22 5xmj:F, 5xmj:J, 5xmj:N
10 7d6v:B 239 219 0.2348 0.2427 0.2648 5.10e-14 7d6x:B
11 5odc:C 184 83 0.0931 0.1250 0.2771 4.82e-05 5odc:I, 5odh:C, 5odh:I, 5odi:C, 5odi:I, 5odq:C, 5odq:I, 5odr:C, 5odr:I
12 7bkb:C 189 125 0.1296 0.1693 0.2560 0.020 7bkb:c, 7bkc:C, 7bkc:c, 7bkd:C, 7bkd:c, 7bke:C, 7bke:c
13 7b0n:I 191 32 0.0648 0.0838 0.5000 0.066 6gcs:I, 7o6y:I, 7o71:I, 6rfq:I, 6rfr:I, 6rfs:I, 6y79:I, 6yj4:I
14 7arc:I 199 73 0.0972 0.1206 0.3288 0.085 7ard:I
15 7zm7:I 185 32 0.0648 0.0865 0.5000 0.20 7zmb:I, 7zmg:I
16 8b9z:I 186 32 0.0607 0.0806 0.4688 0.34 8ba0:I, 8esw:S8, 8esz:S8
17 7ak5:I 178 62 0.0891 0.1236 0.3548 0.45 7ak6:I, 7b93:I, 8c2s:I, 8ca3:I, 8ca5:I, 7dgq:E, 7dgr:E, 7dgs:E, 7dgz:E, 7dh0:E, 7dkf:E2, 6g2j:I, 6g72:I, 5gpn:b, 5gup:H, 8iao:I, 8iap:I, 8ib4:I, 8ib5:I, 8ib9:I, 8iba:I, 8ibd:I, 8ibe:I, 8ic2:I, 8ic3:I, 5lc5:I, 5ldw:I, 5ldx:I, 5lnk:9, 5o31:I, 8olt:I, 8om1:I, 7psa:I, 8pw5:9, 8pw6:9, 8pw7:9, 8q0a:I, 8q0f:I, 8q0j:I, 8q0m:I, 8q0o:I, 8q0q:I, 8q1p:I, 8q1u:I, 8q1y:I, 8q25:I, 8q45:I, 8q46:I, 8q47:I, 8q48:I, 8q49:I, 8q4a:I, 6q9d:S8, 6qa9:S8, 6qbx:S8, 6qc2:S8, 6qc3:S8, 6qc4:S8, 6qc5:S8, 6qc6:S8, 6qc7:S8, 6qc8:S8, 6qc9:S8, 6qca:S8, 6qcf:S8, 7qsd:I, 7qsk:I, 7qsl:I, 7qsm:I, 7qsn:I, 7qso:I, 7r41:I, 7r42:I, 7r43:I, 7r44:I, 7r45:I, 7r46:I, 7r47:I, 7r48:I, 7r4c:I, 7r4d:I, 7r4f:I, 7r4g:I, 8rgp:9, 8rgq:9, 8rgr:9, 8rgt:9, 8ud1:1I, 8ueo:1I, 8uep:1I, 8ueq:1I, 8uer:1I, 8ues:1I, 8uet:1I, 8ueu:1I, 8uev:1I, 8uew:1I, 8uex:1I, 8uey:1I, 8uez:1I, 8ugh:1I, 8ugi:1I, 8ugj:1I, 8ugn:1I, 8ugn:5I, 8ugp:1I, 8ugr:1I, 8ugr:5I, 7v2c:B, 7v2d:B, 7v2e:B, 7v2f:B, 7v2h:B, 7v2k:B, 7v2r:B, 7v30:B, 7v31:B, 7v32:B, 7v33:B, 7v3m:B, 7vb7:B, 7vbn:B, 7vbz:B, 7vwj:B, 7vxp:B, 7vxu:B, 7vy8:B, 7vya:B, 7vyf:B, 7vyh:B, 7vyn:B, 7vz1:B, 7vzv:B, 7vzw:B, 7w00:B, 7w0h:B, 7w0r:B, 7w0y:B, 7w1o:B, 7w1p:B, 7w1t:B, 7w1u:B, 7w1v:B, 7w1z:B, 7w20:B, 7w2k:B, 7w2l:B, 7w2r:B, 7w2u:B, 7w2y:B, 7w31:B, 7w32:B, 7w35:B, 7w4c:B, 7w4d:B, 7w4e:B, 7w4f:B, 7w4g:B, 7w4j:B, 7w4k:B, 7w4l:B, 7w4m:B, 7w4n:B, 7w4q:B, 5xtb:B, 5xtd:B, 5xth:B, 5xti:B, 5xti:BB, 7zd6:9, 7zdh:9, 7zdj:9, 7zdm:9, 7zdp:9, 7zeb:9, 6zk9:9, 6zkc:9, 6zkd:9, 6zke:9, 6zkf:9, 6zkg:9, 6zkh:9, 6zki:9, 6zkj:9, 6zkk:9, 6zkl:9, 6zkm:9, 6zkn:9, 6zko:9, 6zkp:9, 6zkq:9, 6zkr:9, 6zks:9, 6zkt:9, 6zku:9, 6zkv:9, 6zr2:I, 6ztq:I
18 8e73:S8 181 32 0.0607 0.0829 0.4688 0.57 7a23:D, 7a24:D, 7aqr:I, 7ar7:I, 7ar8:I, 7arb:I, 8bee:I, 8bpx:I, 8bq5:I, 8bq6:I, 6x89:S8
19 4hea:9 180 75 0.1012 0.1389 0.3333 0.81 2fug:9, 2fug:G, 2fug:P, 2fug:Y, 4hea:O, 6i0d:9, 6i0d:O, 6i1p:9, 6i1p:O, 3i9v:9, 3i9v:G, 3iam:9, 3iam:G, 3ias:9, 3ias:G, 3ias:P, 3ias:Y, 3m9s:9, 3m9s:G, 6q8o:9, 6q8o:O, 6q8w:9, 6q8w:O, 6q8x:9, 6q8x:O, 6y11:9, 6y11:O, 2ybb:8, 6ziy:9, 6zjl:9, 6zjn:9, 6zjy:9
20 8qby:I 159 21 0.0526 0.0818 0.6190 1.1
21 4xdd:A 582 44 0.0729 0.0309 0.4091 1.2 8aio:A, 8aio:B, 8aj6:A, 8aj6:B, 8aln:A, 8aln:B, 8ap2:A, 8ap2:B, 5byq:A, 5byq:B, 5byr:A, 5byr:B, 5bys:A, 5bys:B, 1c4a:A, 1c4c:A, 3c8y:A, 8cjy:A, 8cjy:B, 1feh:A, 6gly:A, 6gly:B, 6glz:A, 6glz:B, 6gm0:A, 6gm0:B, 6gm1:A, 6gm1:B, 6gm2:A, 6gm2:B, 6gm3:A, 6gm3:B, 6gm4:A, 6gm4:B, 6gm8:A, 6gm8:B, 6h63:A, 6h63:B, 5la3:A, 5la3:B, 6n59:A, 6n6p:A, 6nac:A, 5oef:A, 5oef:B, 8pvm:A, 8pvm:B, 7qhf:A, 7qhf:B, 8qm3:A, 8qm3:B, 4xdc:A, 4xdc:B, 4xdd:B, 6yf4:A, 6yf4:B
22 6h8k:I 137 32 0.0688 0.1241 0.5312 1.3
23 5dat:e1 76 42 0.0607 0.1974 0.3571 1.4 7a1g:N, 7b7d:N, 8bn3:E1, 8bqd:N, 8bqx:N, 8cah:N, 8cas:O, 5dat:E1, 5dc3:E1, 5dc3:e1, 5dge:E1, 5dge:e1, 5dgf:E1, 5dgf:e1, 5dgv:E1, 5dgv:e1, 6eml:N, 8eub:Bf, 8evp:Bf, 8evq:Bf, 8evr:Bf, 8evs:Bf, 8evt:Bf, 8ewb:Bf, 8ewc:Bf, 5fci:E1, 5fci:e1, 5fcj:E1, 5fcj:e1, 6gq1:AW, 6gqb:AW, 6gqv:AW, 6hhq:g, 6hhq:e1, 5i4l:E1, 5i4l:e1, 6i7o:N, 6i7o:Nb, 3j6x:31, 3j6y:31, 3j77:31, 3j78:31, 5juo:CC, 5jup:CC, 5jus:CC, 5jut:CC, 5juu:CC, 8k2d:Sf, 8k82:Sf, 5lyb:E1, 5lyb:e1, 5m1j:f2, 5mc6:N, 5mei:e1, 5mei:g, 7mpi:Bf, 7mpj:Bf, 7n8b:Bf, 5ndg:E1, 5ndw:E1, 5ndw:e1, 7nrc:SN, 7nrd:SN, 5obm:E1, 5obm:e1, 5on6:e1, 5on6:g, 7osa:eS31, 6q8y:N, 6rbe:f, 7rr5:Sf, 6s47:Bg, 6snt:f, 6sv4:N, 6sv4:Nb, 6sv4:Nc, 6t4q:Sf, 6t7i:Sf, 6t7t:Sf, 6t83:fb, 6t83:6, 5tbw:g, 5tbw:e1, 6tb3:N, 5tga:E1, 5tga:e1, 5tgm:E1, 5tgm:e1, 6tnu:N, 4u3m:E1, 4u3m:e1, 4u3n:E1, 4u3n:e1, 4u3u:E1, 4u3u:e1, 4u4n:E1, 4u4n:e1, 4u4o:E1, 4u4o:e1, 4u4q:E1, 4u4q:e1, 4u4r:E1, 4u4r:e1, 4u4u:E1, 4u4u:e1, 4u4y:E1, 4u4y:e1, 4u4z:E1, 4u4z:e1, 4u50:E1, 4u50:e1, 4u51:E1, 4u51:e1, 4u52:E1, 4u52:e1, 4u53:E1, 4u53:e1, 4u55:E1, 4u55:e1, 4u56:E1, 4u56:e1, 4u6f:E1, 4u6f:e1, 6wdr:f, 5wyj:Sg, 8y0u:Sf, 6z6j:Sf, 6z6k:Sf, 6zce:g, 7zpq:Af, 7zrs:Af, 6zu9:O, 7zuw:Af, 7zux:Df, 6zvi:Q, 7zw0:sN
24 8b6f:AL 218 22 0.0526 0.0596 0.5909 1.5 8bqs:AL, 8gym:s8, 8gym:S8, 8gzu:s8, 8gzu:S8, 7tgh:S8
25 6kr4:C 575 71 0.0850 0.0365 0.2958 1.9
26 5odc:A 653 22 0.0445 0.0168 0.5000 2.3 5odc:G, 5odh:A, 5odh:G, 5odi:A, 5odi:G, 5odq:A, 5odq:G, 5odr:A, 5odr:G
27 4v88:Cf 76 40 0.0567 0.1842 0.3500 2.6 4uer:9, 4v88:Af, 4v8y:A5, 4v8z:A5
28 8ags:AAA 298 33 0.0526 0.0436 0.3939 3.0 8agm:AAA, 8agm:BBB, 8agm:CCC, 8agm:DDD, 8agn:AAA, 8agn:BBB, 8agn:CCC, 8agn:DDD, 8agp:AAA, 8agp:BBB, 8ags:BBB, 5ng7:B
29 6jh5:A 232 28 0.0445 0.0474 0.3929 3.2 6jhj:A, 6jia:A, 6m6p:A
30 5gv2:C 307 112 0.1296 0.1042 0.2857 4.5 5gs9:B, 5gs9:C, 5gs9:D, 5gt7:B, 5gv2:A, 5i2c:B, 5i2c:C, 5i2c:D
31 8rbq:C 477 21 0.0405 0.0210 0.4762 5.7 8ahx:C, 8rb8:C, 8rb9:C, 8rbm:C
32 5koh:A 483 46 0.0567 0.0290 0.3043 5.7 5koh:C, 5koj:A, 5koj:C
33 4ivn:A 264 49 0.0567 0.0530 0.2857 7.8 4ivn:B
34 2r5c:B 419 73 0.0769 0.0453 0.2603 8.3 2r5e:A, 2r5e:B, 1yiy:A, 1yiy:B
35 5ch7:B 329 22 0.0405 0.0304 0.4545 8.4 5ch7:D, 5ch7:F, 5chc:B, 5chc:D, 5chc:F, 5e7o:B, 5e7o:D, 5e7o:F, 5e7o:H, 5e7o:J, 5e7o:L, 4ydd:B, 4ydd:D, 4ydd:F
36 7zc6:C 435 92 0.0931 0.0529 0.2500 8.5
37 4irx:A 296 83 0.0972 0.0811 0.2892 9.1 4irx:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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