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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PEAVARLGRVRWTQQRHAEAAVLLQQASDAAPEHPGIALWLGHALEDAGQAEAAAAAYTRAHQLLPEEPYITAQLLNWRR
RLCDWRALDVLSAQVRAAVAQGVGAVEPFAFLSEDASAAEQLACARTRAQAIAASVRPLAPTRVRSKGPLRVGFVSNGFG
AHPTGLLTVALFEALQRRQPDLQMHLFATSGDDGSTLRTRLAQASTLHDVTALGHLATAKHIRHHGIDLLFDLRGWGGGG
RPEVFALRPAPVQVNWLAYPGTSGAPWMDYVLGDAFALPPALEPFYSEHVLRLQGAFQPSDTSRVVAEPPSRTQCGLPEQ
GVVLCCFNNSYKLNPQSMARMLAVLREVPDSVLWLLSGPGEADARLRAFAHAQGVDAQRLVFMPKLPHPQYLARYRHADL
FLDTHPYNAHTTASDALWTGCPVLTTPGETFAARVAGSLNHHLGLDEMNVADDAAFVAKAVALASDPAALTALHARVDVL
RRASGVFHMDGFADDFGALLQALARRHGWLGI

The query sequence (length=512) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2jlb:A 548 512 1.0000 0.9343 1.0000 0.0 2jlb:B, 2vsn:A, 2vsn:B, 2xgm:A, 2xgm:B, 2xgo:A, 2xgs:A, 2xgs:B
2 5djs:A 520 332 0.2129 0.2096 0.3283 1.41e-37 5djs:B, 5djs:C, 5djs:D
3 7y4i:A 822 355 0.1973 0.1229 0.2845 6.08e-32 8dti:A, 8dti:B
4 5lwv:A 711 189 0.1309 0.0942 0.3545 7.15e-31 5bnw:A, 6e37:A, 8fe6:A, 8fe6:C, 8fe6:E, 8fe6:G, 4gyw:A, 4gyy:A, 4gyy:C, 4gz3:A, 5hgv:A, 5nps:A, 6tka:AAA, 5vie:A, 5vie:C, 5vif:A
5 5lwv:A 711 267 0.1621 0.1167 0.3109 2.19e-27 5bnw:A, 6e37:A, 8fe6:A, 8fe6:C, 8fe6:E, 8fe6:G, 4gyw:A, 4gyy:A, 4gyy:C, 4gz3:A, 5hgv:A, 5nps:A, 6tka:AAA, 5vie:A, 5vie:C, 5vif:A
6 7yeh:A 1020 182 0.1289 0.0647 0.3626 1.38e-30 4ay5:A, 4ay5:B, 4ay5:C, 4ay5:D, 4ay6:A, 4ay6:B, 4ay6:C, 4ay6:D, 5c1d:A, 4cdr:A, 4cdr:B, 4cdr:C, 4cdr:D, 8cm9:A, 8cm9:B, 8cm9:D, 8cm9:C, 8fe7:A, 8fe7:C, 8fe7:E, 8fe7:G, 8fuf:A, 8fuf:C, 8fuf:E, 8fuf:G, 4gyw:C, 4gz3:C, 4gz5:A, 4gz5:B, 4gz5:C, 4gz5:D, 4gz6:A, 4gz6:B, 4gz6:C, 4gz6:D, 5hgv:C, 6ibo:A, 5lvv:A, 6ma1:A, 6ma2:A, 6ma3:A, 6ma4:A, 6ma5:A, 4n39:A, 4n3a:A, 4n3b:A, 4n3c:A, 5npr:A, 3pe3:A, 3pe3:B, 3pe3:C, 3pe3:D, 3pe4:A, 3pe4:C, 6q4m:A, 3tax:A, 3tax:C, 1w3b:A, 4xi9:A, 4xi9:B, 4xi9:C, 4xi9:D, 4xif:A, 4xif:B, 4xif:C, 4xif:D
7 7yeh:A 1020 333 0.1836 0.0922 0.2823 3.26e-28 4ay5:A, 4ay5:B, 4ay5:C, 4ay5:D, 4ay6:A, 4ay6:B, 4ay6:C, 4ay6:D, 5c1d:A, 4cdr:A, 4cdr:B, 4cdr:C, 4cdr:D, 8cm9:A, 8cm9:B, 8cm9:D, 8cm9:C, 8fe7:A, 8fe7:C, 8fe7:E, 8fe7:G, 8fuf:A, 8fuf:C, 8fuf:E, 8fuf:G, 4gyw:C, 4gz3:C, 4gz5:A, 4gz5:B, 4gz5:C, 4gz5:D, 4gz6:A, 4gz6:B, 4gz6:C, 4gz6:D, 5hgv:C, 6ibo:A, 5lvv:A, 6ma1:A, 6ma2:A, 6ma3:A, 6ma4:A, 6ma5:A, 4n39:A, 4n3a:A, 4n3b:A, 4n3c:A, 5npr:A, 3pe3:A, 3pe3:B, 3pe3:C, 3pe3:D, 3pe4:A, 3pe4:C, 6q4m:A, 3tax:A, 3tax:C, 1w3b:A, 4xi9:A, 4xi9:B, 4xi9:C, 4xi9:D, 4xif:A, 4xif:B, 4xif:C, 4xif:D
8 5a01:A 681 308 0.1680 0.1263 0.2792 1.56e-28 5a01:B, 5a01:C
9 5a01:A 681 190 0.1309 0.0984 0.3526 1.02e-27 5a01:B, 5a01:C
10 8p0o:A 622 244 0.1094 0.0900 0.2295 6.98e-04 8p0o:B, 8p0p:A, 8p0p:B, 8p0q:A, 8p0q:B
11 3q3h:A 620 232 0.1016 0.0839 0.2241 0.017 8j30:A, 8j30:B
12 3q3h:B 595 226 0.0996 0.0857 0.2257 0.066
13 1dfo:B 417 51 0.0312 0.0384 0.3137 0.94 1dfo:A, 1dfo:D, 1dfo:C, 1eqb:A, 1eqb:B, 1eqb:D, 1eqb:C, 3g8m:A
14 7x5o:B 412 37 0.0234 0.0291 0.3243 1.8 7v3d:A, 7v3d:B, 7x5n:A, 7x5n:B, 7x5o:A
15 9cp7:A 436 86 0.0488 0.0573 0.2907 1.9 9cp7:B, 9cp8:A, 9cp8:B, 9cp9:A, 9cp9:B, 8v35:A, 8v36:A, 8v37:A
16 4n0w:A 416 55 0.0312 0.0385 0.2909 2.2 4n0w:B, 4n0w:C, 4n0w:D, 4ot8:A, 4ot8:C, 4ot8:B, 4ot8:D, 4otl:A, 4otl:B, 4otl:D, 4otl:C
17 4ayb:B 1103 146 0.0664 0.0308 0.2329 3.0 3hkz:B, 3hkz:J, 2pmz:B, 2pmz:R, 4v8s:AR, 4v8s:BB, 2waq:B, 2wb1:B, 2wb1:R, 2y0s:B, 2y0s:R
18 6uld:A 428 61 0.0391 0.0467 0.3279 4.0 6uld:B
19 9boh:A 402 37 0.0234 0.0299 0.3243 5.7 9boh:B, 9bow:A, 9bow:B, 9bpe:A, 9bpe:B, 2dkj:A, 2dkj:B, 8ssy:A, 8ssy:B, 8sui:B
20 5dhi:A 536 74 0.0410 0.0392 0.2838 9.9 5dhk:A, 4di5:A, 5eas:A, 5eat:A, 5eau:A, 1hx9:A, 1hxa:A, 1hxc:A, 1hxg:A, 5ik0:A, 5ik6:A, 5ik9:A, 5ika:A, 5ikh:A, 5il3:A, 5il8:A, 5ild:A, 5ilh:A, 5ili:A, 5ily:A, 3lz9:A, 3m00:A, 3m01:A, 3m02:A, 4rnq:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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