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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PDKKGYIIDIDGVIGKSVTPIPEGVEGVKKLKELGKKIIFVSNNSTRSRRILLERLRSFGLEVGEDEILVATYATARFIA
REKPNAKVFTTGEEGLIEELRLAGLEIVDYDEAEYLVVGSNRKINFELMTKALRACLRGIRYIATNPDRIFPAEDGPIPG
TGMIIGALYWMTGREPDVVVGKPSEVIMREALDILGLDAKDVAVVGDQIDVDVAAGKAIGAETVLVLTGVTTRENLDQMI
ERHGLKPDYVFNSLKDMVEAL

The query sequence (length=261) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4jdp:B 265 261 1.0000 0.9849 1.0000 0.0 4jdp:A, 3qgm:A, 3qgm:B, 3qgm:C, 3qgm:D
2 4o8c:B 255 253 0.3257 0.3333 0.3360 6.91e-42
3 1zjj:B 263 263 0.3333 0.3308 0.3308 1.34e-40 1zjj:A
4 2c4n:A 250 254 0.3027 0.3160 0.3110 1.49e-38
5 1ydf:A 255 255 0.3333 0.3412 0.3412 1.41e-36
6 5gyn:A 295 277 0.3410 0.3017 0.3213 1.17e-29 5aes:A, 5aes:B, 4bx0:A, 4bx2:A, 4bx2:B, 4bx3:A, 4bx3:B, 2cfr:A, 2cfs:A, 2cft:A, 9em1:A, 2oyc:A, 2p27:A, 2p69:A, 8qfw:A, 8qfw:B, 8s8a:A
7 7po7:H 311 295 0.3180 0.2669 0.2814 3.32e-27 7poe:A, 7poe:B
8 4bkm:A 304 289 0.3142 0.2697 0.2837 2.63e-25 4bkm:B, 4bkm:C, 4bkm:D
9 4i9f:A 336 256 0.2835 0.2202 0.2891 3.45e-25 4i9g:A, 4i9g:B
10 2ho4:B 252 227 0.2337 0.2421 0.2687 9.87e-19 2ho4:A
11 2x4d:A 270 233 0.2222 0.2148 0.2489 2.83e-11
12 2hx1:A 284 270 0.2452 0.2254 0.2370 1.60e-07 2hx1:B, 2hx1:C, 2hx1:D
13 2x4d:B 213 68 0.0881 0.1080 0.3382 0.004
14 1rvv:A 154 81 0.0996 0.1688 0.3210 0.86 1rvv:E, 1rvv:B, 1rvv:C, 1rvv:D, 1rvv:F, 1rvv:G, 1rvv:H, 1rvv:I, 1rvv:J, 1rvv:K, 1rvv:O, 1rvv:L, 1rvv:M, 1rvv:N, 1rvv:P, 1rvv:Q, 1rvv:R, 1rvv:S, 1rvv:T, 1rvv:U, 1rvv:V, 1rvv:W, 1rvv:X, 1rvv:Y, 1rvv:Z, 1rvv:4, 1rvv:1, 1rvv:2, 1rvv:3, 1zis:A, 1zis:E, 1zis:B, 1zis:C, 1zis:D, 1zis:F, 1zis:G, 1zis:H, 1zis:I, 1zis:J
15 2no5:B 226 85 0.0920 0.1062 0.2824 1.5 2no5:A
16 3qnm:A 231 85 0.0766 0.0866 0.2353 1.9
17 4ygr:A 215 50 0.0575 0.0698 0.3000 2.0 4ygs:A
18 7ef7:A 236 48 0.0613 0.0678 0.3333 2.2 7ef6:A
19 4knv:A 241 49 0.0613 0.0664 0.3265 2.4 4knv:B, 4knw:A, 4knw:B, 4knw:C
20 5mc6:h 1121 47 0.0766 0.0178 0.4255 2.8 4a4k:A, 4a4k:C, 4a4k:E, 4a4k:G, 4a4k:I
21 4ohf:B 458 52 0.0690 0.0393 0.3462 4.0 4ohf:A, 4ohf:C, 4ohf:D
22 2vb6:A 724 79 0.0881 0.0318 0.2911 5.2
23 3l8e:A 185 80 0.0920 0.1297 0.3000 5.2 3esq:A, 3esr:A, 2gmw:A, 2gmw:B, 3l1u:A, 3l1u:B, 3l1v:A, 3l1v:B, 3l8e:B, 3l8f:A, 3l8g:A
24 4b8y:A 277 86 0.0728 0.0686 0.2209 6.0 4fil:A, 4fil:B, 4fil:C, 4fil:D
25 7s3l:A 254 32 0.0498 0.0512 0.4062 8.2
26 4qs7:A 455 97 0.1034 0.0593 0.2784 9.0 4qs9:A
27 3j79:I 207 120 0.1073 0.1353 0.2333 9.7 3jbn:AI, 3jbo:AI, 3jbp:AI, 8tpu:AI, 5umd:I

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218