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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PDGEVDPAVWGKAYPTEYEMWKKTKSKYKRGFDADHVTYDKLSEFPYMALLFNGWGFGIAYNEPRGHANMVRDQLEIDSA
RLKSGGVCLTCKTPYAPKLEKEMGIDYFKTPFKDVLAKIPEKHKTLGVACIDCHDNKDMSLRISRGFTLGEALKKLGVDQ
AKLSRQEMRSLVCAQCHVTYNIPKDADKKSIGVYFPWQGSKMGNISVENIIKQIRSDASVGEWTQTVTGFKLGFIRHPEY
ELFSNNSVHWKAGAACTDCHMPYTVSDHRVMSPLKNDMKACIQCHTEKPEWLRDQVIAIQDRTVSLMLRSGYATATVAKL
FEKAHAAQAQGKQIDKALYDRAKDLYEEAFYRCVFIGAENSVGFHNPTEAMRVLGDATAFATKAEALLRQALAKAGVDVP
LTVNLELNKYLDQRGEKKLTFDPKVEIKDPYGVQVRF

The query sequence (length=437) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8bcx:D 444 443 0.9908 0.9752 0.9774 0.0 8bcx:A, 8bcx:B, 8bcx:C
2 6v0a:B 444 444 0.6682 0.6577 0.6577 0.0 6v0a:A, 6v0a:C, 6v0a:D, 6v0a:E, 6v0a:F
3 2j7a:B 498 407 0.3021 0.2651 0.3243 6.72e-51 2j7a:A, 2j7a:D, 2j7a:E, 2j7a:G, 2j7a:H, 2j7a:J, 2j7a:K, 2j7a:M, 2j7a:N, 2j7a:P, 2j7a:Q, 2vr0:A, 2vr0:B, 2vr0:D, 2vr0:E
4 1oah:B 482 370 0.2563 0.2324 0.3027 3.82e-47 1oah:A
5 6p73:A 439 403 0.2952 0.2938 0.3201 1.85e-45 6p73:B, 3ubr:A, 3ubr:B
6 1qdb:A 473 413 0.2975 0.2748 0.3148 2.30e-45 1qdb:B, 1qdb:C
7 3bnf:A 471 422 0.2952 0.2739 0.3057 8.32e-45 3bng:A, 3bnh:A, 3bnj:A, 2e80:A, 2e81:A, 1fs7:A, 1fs8:A, 1fs9:A
8 1gu6:A 441 417 0.2700 0.2676 0.2830 4.99e-37 1gu6:G, 1gu6:C, 1gu6:E, 3l1t:A, 3l1t:B, 3l1t:C, 3l1t:D, 2rdz:A, 2rdz:B, 2rdz:C, 2rdz:D, 2rf7:A, 2rf7:B, 2rf7:C, 2rf7:D, 3tor:A, 3tor:D, 3tor:B, 3tor:C, 4wjy:A, 4wjy:B
9 8rv0:Y 495 471 0.2723 0.2404 0.2527 2.75e-28 8rvm:YYY, 8rxu:AAA, 8rxu:MMM, 8rxu:YYY
10 3f29:B 520 438 0.2449 0.2058 0.2443 5.56e-21 3d1i:A, 3d1i:B, 3f29:A, 3fo3:A, 3fo3:B, 3gm6:A, 3gm6:B, 4l38:A, 4l38:B, 4l3x:A, 4l3x:B, 4l3y:A, 4l3y:B, 4l3z:A, 4l3z:B, 3lg1:A, 3lg1:B, 3lgq:A, 3lgq:B, 3mmo:A, 3mmo:B, 2ot4:A, 2ot4:B, 3owm:A, 3owm:B, 4q0t:A, 4q0t:B, 4q17:A, 4q17:B, 4q1o:A, 4q1o:B, 4q4u:A, 4q4u:B, 4q5b:A, 4q5b:B, 4q5c:A, 4q5c:B, 3rkh:A, 3rkh:B, 3s7w:A, 3s7w:B, 3sce:A, 3sce:B, 3uu9:A, 3uu9:B, 2zo5:A, 2zo5:B
11 3sxq:A 519 416 0.2197 0.1850 0.2308 3.97e-15 3sxq:B, 3ttb:A, 3ttb:B
12 6i5b:A 484 152 0.0892 0.0806 0.2566 0.13 6i5b:B
13 7opk:A 649 75 0.0549 0.0370 0.3200 0.47
14 6btm:A 221 91 0.0595 0.1176 0.2857 0.49
15 2e84:A 513 257 0.1396 0.1189 0.2374 0.78
16 6f0k:A 207 59 0.0481 0.1014 0.3559 1.0
17 5acn:A 754 85 0.0572 0.0332 0.2941 1.2 1aco:A, 6acn:A, 7acn:A, 8acn:A, 1ami:A, 1amj:A, 1b0j:A, 1b0k:A, 1b0m:A, 1c96:A, 1c97:A, 1fgh:A, 1nis:A, 1nit:A
18 8f5f:A 326 36 0.0320 0.0429 0.3889 1.4 4dzy:A, 4e00:A, 4e01:A, 4e02:A, 8egd:A, 8egf:A, 8egq:A, 8egu:A, 8f4q:A, 8f5f:B, 8f5j:A, 8f5s:A, 8f5s:B, 1gjv:A, 1gkz:A, 4h7q:A, 4h81:A, 4h85:A, 3tz0:A, 3tz2:A, 3tz4:A, 3tz5:A, 3vad:A
19 6dtu:A 375 50 0.0320 0.0373 0.2800 2.4 6dtu:B, 2gha:A, 2gha:B
20 7wrx:H 594 63 0.0435 0.0320 0.3016 2.8 7wrx:A, 7wrx:B, 7wrx:C, 7wrx:D, 7wrx:E, 7wrx:F, 7wrx:G, 7wrx:I, 7wrx:J, 7wrx:K, 7wrx:L
21 2ozy:A 142 47 0.0366 0.1127 0.3404 6.2 2p0b:A
22 2owq:B 224 49 0.0343 0.0670 0.3061 8.4 8j86:B, 8j8f:B, 8j8g:B, 4lzb:A, 4lzb:B, 4lzb:C, 4lzb:D, 4lzb:E, 4lzb:F, 4lzb:G, 4lzb:H, 4lzb:I, 4lzb:J, 4lzb:K, 4lzb:L, 2owq:A, 4qcb:B, 4qcb:A, 8wpe:C, 8wpf:C, 8wpk:C, 8wpp:C, 4ygm:B, 4ygm:A, 4yig:A, 4yig:E, 4yig:I
23 2b7r:A 568 91 0.0526 0.0405 0.2527 10.0 2b7s:A, 1e39:A, 1jrx:A, 1jrx:B, 1jry:A, 1jry:B, 1jrz:A, 1jrz:B, 1kss:A, 1ksu:A, 1ksu:B, 1lj1:A, 1lj1:B, 1m64:A, 1m64:B, 1p2e:A, 1p2h:A, 1q9i:A, 1qjd:A, 1y0p:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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