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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PDALAARFNASLAFDRALWREDLWQNRVHARMLHAVGLLSAEELEAILKGLDRIEEEIEAGTFPWREELEDVHMNLEARL
TELVGPPGGKLHTARSRNDQVATDLRLYLRGAIDELLALLLALRRVLVREAEKHLDPLYVLPGYTHLQRAQPVLLAHWFL
AYYEMLKRDAGRLEDAKERLNESPLGAAALAGTGFPIDRHFTARELGFKAPMRNSLDAVASRDFALEVLSALNIGMLHLS
RMAEELILYSTEEFGFVEVPDAFATGSSIMPQKKNPDILELIRAKAGRVLGAFVGLSAVVKGLPLAYNKDLQEDKEPLLD
ALATYRDSLRLLAALLPGLKWRRERMWRAAEGGYTLATELADYLAEKGLPFREAHHVVGRLVRRLVEEGRALKDLTLEEL
QAHHPLFAEDALPLLRLETAIHRRRSYGGTAPEAVRERLEEAKKEVGL

The query sequence (length=448) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2e9f:B 450 448 1.0000 0.9956 1.0000 0.0 2e9f:A, 2e9f:D, 2e9f:C
2 1tj7:B 451 442 0.4955 0.4922 0.5023 7.38e-145
3 1k7w:D 450 440 0.4263 0.4244 0.4341 7.53e-126 1dcn:D, 1hy0:A, 1hy0:B, 1k7w:A, 1k7w:C, 1k7w:B, 1tjw:A, 1tjw:B, 1tjw:C, 1tjw:D
4 6ien:B 454 440 0.4330 0.4273 0.4409 7.80e-97 6ien:A, 6ien:C, 6ien:D
5 6g3f:A 497 446 0.3214 0.2897 0.3229 8.70e-60 6g3g:A, 6g3h:A, 6g3i:A, 6rx8:A
6 3r6v:G 463 405 0.2188 0.2117 0.2420 6.20e-19 3r6q:A, 3r6q:D, 3r6q:E, 3r6q:H, 3r6v:A, 3r6v:B, 3r6v:C, 3r6v:D, 3r6v:E, 3r6v:F, 3r6v:H, 3r6y:F
7 4apb:D 462 289 0.1719 0.1667 0.2664 6.52e-10 4adl:A, 4adl:C, 4adl:B, 4adl:D, 4apb:A, 4apb:C, 4apb:B, 5f91:A, 5f91:C, 6s43:A, 6s43:C, 6s7k:A, 6s7k:C, 6s7s:A, 6s7s:C, 6s7u:A, 6s7u:C, 6s7w:A, 6s7w:C, 6s7z:A, 6s7z:C, 6s88:A, 6s88:C
8 6wng:A 466 344 0.1763 0.1695 0.2297 2.09e-09 6wng:B, 6wng:D, 6wng:C
9 1fuo:A 456 300 0.1719 0.1689 0.2567 5.35e-09 1fuo:B, 1fup:A, 1fup:B, 1fuq:A, 1fuq:B
10 7lub:B 462 284 0.1696 0.1645 0.2676 1.18e-08 7lub:A
11 7c18:B 464 223 0.1183 0.1142 0.2377 6.84e-08 7c18:A, 7c18:C, 7c18:D
12 3oce:A 461 294 0.1741 0.1692 0.2653 7.91e-08 3oce:B, 3oce:C, 3oce:D
13 2x75:A 427 239 0.1295 0.1358 0.2427 1.45e-05
14 8jxr:C 341 129 0.0737 0.0968 0.2558 0.21
15 7rxc:B 439 129 0.0737 0.0752 0.2558 0.46 7rxd:B
16 7cr6:C 325 148 0.0938 0.1292 0.2838 0.50 7cr6:B, 7cr6:D, 7cr6:A, 7cr8:J, 7cr8:K, 7cr8:L, 7cr8:I, 7cr8:R, 7cr8:S, 7cr8:T, 7cr8:Q, 7cr8:b, 7cr8:c, 7cr8:d, 7cr8:a, 7cr8:j, 7cr8:k, 7cr8:l, 7cr8:i, 7cr8:r, 7cr8:s, 7cr8:t, 7cr8:q, 7cr8:B, 7cr8:C, 7cr8:D, 7cr8:A
17 4efc:A 452 259 0.1406 0.1394 0.2432 0.79 4efc:B
18 4c5y:A 436 101 0.0580 0.0596 0.2574 1.5 4c5y:B
19 1dii:A 515 85 0.0580 0.0505 0.3059 3.5 1dii:B, 1diq:A, 1diq:B, 1wve:A, 1wve:B, 1wvf:A
20 1xdp:A 687 58 0.0446 0.0291 0.3448 5.1 1xdp:B
21 5nx9:D 477 192 0.1183 0.1111 0.2760 8.1 2j91:A, 2j91:D, 2j91:B, 2j91:C, 5nx9:A, 5nx9:B, 5nxa:A, 5nxa:B, 5nxa:D, 5nxa:E, 5nxa:G, 5nxa:H, 5nxa:F, 2vd6:A, 2vd6:D, 2vd6:B, 2vd6:C
22 1fzi:A 512 30 0.0290 0.0254 0.4333 9.3 1fyz:A, 1fyz:B, 1fz0:A, 1fz0:B, 1fz1:A, 1fz1:B, 1fz2:A, 1fz2:B, 1fz3:A, 1fz3:B, 1fz4:A, 1fz4:B, 1fz5:A, 1fz5:B, 1fz6:A, 1fz6:B, 1fz7:A, 1fz7:B, 1fz8:A, 1fz8:B, 1fz9:A, 1fz9:B, 1fzh:A, 1fzh:B, 1fzi:B, 4gam:A, 4gam:F, 4gam:K, 4gam:P, 1mmo:D, 1mmo:E, 1mty:D, 1mty:E, 7tc7:D, 7tc7:E, 7tc8:D, 7tc8:E, 1xmf:A, 1xmf:B, 1xmh:A, 1xmh:B, 1xu3:A, 1xu3:B, 1xu5:A, 1xu5:B, 1xvb:A, 1xvb:B, 1xvc:A, 1xvc:B, 1xvd:A, 1xvd:B, 1xve:A, 1xve:B, 1xvf:A, 1xvf:B, 1xvg:A, 1xvg:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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