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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PCAYGLLLHPTSLPGPWGVGVLGEEARGFLRFLKEAGARYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLVDRGFV
RLEDPGFPEGRVDYGLLYAWKWPALRAAFQGFRQKASPEEKEDFARFQEEEAWWLRDYALFMTLKSHHGGLPWNAWPLAL
RTREERALKEAEASLAEEIAFHAFTQWLFFRQWGALKEEAEALGIAFIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVV
AGVPPDYFSETGQRWGNPLYRWEVLEEEGFSFWIARLRKALELFHLVRIDHFRGFEAYWEIPASCPTAVEGRWVKAPGEK
LFARIQEAFGRIPILAEDLGVITPEVEALRDRFGLPGMKVLQFAFDNGMENPFLPHNYPEHGRVVVYTGTHDNDTTLGWY
RTATPHERDFLKRYLADWGITFREEAEVPWALMRLGMASRARLAVYPVQDVLALGSEARMNYPGRPSGNWAWRLRPGEIK
EEHGERLLSLAEATGRV

The query sequence (length=497) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2x1i:A 497 497 1.0000 1.0000 1.0000 0.0
2 1esw:A 500 497 0.8672 0.8620 0.8672 0.0 5jiw:A, 2owc:A, 2oww:A
3 6lx2:A 523 477 0.4205 0.3996 0.4382 2.07e-130 6lx1:A
4 6m6t:C 499 503 0.4064 0.4048 0.4016 1.12e-125 6m6t:A, 6m6t:B, 6m6t:D, 6m6t:E, 6m6t:F, 6m6t:G, 6m6t:H
5 5csu:A 518 500 0.4165 0.3996 0.4140 3.01e-124 5cps:A, 5cps:B, 5cpt:A, 5cpt:B, 5cq1:A, 5cq1:B, 5csu:B, 5csy:A, 5csy:B
6 4s3q:A 682 321 0.1811 0.1320 0.2804 1.50e-22 4s3r:A
7 5b68:A 703 372 0.1851 0.1309 0.2473 2.32e-13
8 6lck:A 479 126 0.0744 0.0772 0.2937 0.30 6lck:B, 6lck:C, 6lcl:A, 6lcl:C, 6lcl:E
9 1odz:A 379 57 0.0362 0.0475 0.3158 7.6 1gvy:A, 1gw1:A, 1j9y:A, 1odz:B, 1r7o:A, 2whm:A
10 8bcj:B 250 28 0.0221 0.0440 0.3929 8.2 8bcj:A, 8bcj:C, 8bcj:D
11 4bxs:V 1262 30 0.0241 0.0095 0.4000 8.2
12 8x43:A 327 60 0.0362 0.0550 0.3000 8.6 8j00:A, 8j00:B, 8j00:C, 8j00:D, 8x43:G, 8x43:C, 8x43:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218