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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVIVSVLKGSFVFTADMVRILGDFGVPTRVEFLRGL
CDIRGKHVLVLEDILDTALTLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREV
RDVVILKPSVYETWGKEE

The query sequence (length=178) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6aps:A 185 177 0.9888 0.9514 0.9944 1.43e-126 6aps:B, 6apt:A, 6apt:B, 6apu:A, 6apu:B, 6apv:A, 6apv:B, 6apv:C, 6apv:D, 5jsq:A, 5jsq:B, 5jv5:A, 5jv5:B, 5k51:A, 5k51:B, 5k51:C, 5k51:D, 5kam:A, 5kam:C, 5kap:A, 5kap:B, 6mxg:A, 6mxg:B, 7sb7:A, 7sb7:B, 8tr1:A, 8tr1:B, 8tr1:C, 8tr1:D, 8ts4:A, 8ts4:B
2 1p17:B 204 181 0.5506 0.4804 0.5414 7.38e-66 1i0i:A, 1i0i:B, 1i0l:A, 1i0l:B, 1i13:A, 1i13:B, 1i14:A, 1i14:B, 1p17:A, 1p17:C, 1p17:D, 1p18:A, 1p18:B, 1p19:A, 1p19:B, 1p19:C, 1p19:D, 1tc1:A, 1tc1:B, 1tc2:A, 1tc2:B
3 7cmj:A 184 182 0.4157 0.4022 0.4066 9.66e-45 1pzm:A, 1pzm:B
4 6mxc:C 220 197 0.4494 0.3636 0.4061 1.28e-44 6aqo:A, 6aqo:B, 6aqo:C, 6aqo:D, 6aqo:E, 6aqo:F, 6ar9:A, 6ar9:B, 6ar9:C, 6ar9:D, 6ar9:E, 6ar9:F, 6mxb:A, 6mxb:B, 6mxb:C, 6mxb:D, 6mxb:E, 6mxb:F, 6mxc:A, 6mxc:B, 6mxc:D, 6mxc:E, 6mxc:F, 6mxd:A, 6mxd:B, 6mxd:C, 6mxd:D, 7scr:A, 7scr:C, 7scr:B, 7scr:D, 7scr:E, 7scr:F
5 8fx3:B 223 196 0.4213 0.3363 0.3827 4.06e-41 8fwy:A, 8fwy:B, 8fwz:A, 8fwz:B, 8fx0:A, 8fx0:B, 8fx1:A, 8fx1:B, 8fx2:A, 8fx2:B, 8fx3:A
6 3kb8:A 201 177 0.3708 0.3284 0.3729 4.03e-28 6d9r:A, 6d9r:B, 6d9s:A, 6d9s:B, 3h83:A, 3h83:B, 3kb8:B
7 5kny:B 187 182 0.3258 0.3102 0.3187 7.94e-26 5knp:A, 5knp:B, 5knp:C, 5knp:D, 5knq:A, 5knq:B, 5knq:C, 5knq:D, 5kny:A, 5kny:C, 5kny:D, 4rht:A, 4rht:B, 4rht:C, 4rht:D, 4rhu:A, 4rhu:B, 4rhu:C, 4rhu:D, 4rhu:E, 4rhu:F, 4rhx:A, 4rhx:B, 4rhx:C, 4rhx:D, 4rhy:A, 4rhy:B, 4rhy:C, 4rhy:D
8 4qyi:B 171 165 0.3146 0.3275 0.3394 3.81e-25 4qyi:A, 4qyi:C, 4qyi:D, 4qyi:E
9 4pfq:C 184 178 0.3258 0.3152 0.3258 8.30e-25 4pfq:A, 4pfq:B, 4pfq:D, 4pfq:E, 4pfq:F, 4pfq:G, 4pfq:H
10 5knx:B 176 166 0.3315 0.3352 0.3554 7.60e-24 1g9s:A, 1g9s:B, 1g9t:A, 1g9t:B, 1grv:B, 1grv:A, 1j7j:A, 1j7j:B, 5knr:A, 5knr:B, 5kns:A, 5kns:B, 5knt:A, 5knt:B, 5knu:A, 5knu:B, 5knv:A, 5knv:B, 5knx:A
11 2geb:A 184 181 0.3146 0.3043 0.3094 1.22e-22 1r3u:A, 1r3u:B, 1yfz:A, 1yfz:B
12 5ipf:A 201 166 0.3034 0.2687 0.3253 1.20e-20 5ipf:B, 5ipf:C, 5ipf:D
13 6igs:B 167 171 0.2809 0.2994 0.2924 3.04e-20 6igs:A, 6igs:C, 6igs:D
14 1hgx:A 164 166 0.2921 0.3171 0.3133 5.14e-20
15 3acc:A 166 166 0.2865 0.3072 0.3072 1.21e-16 3acd:A
16 5brn:B 194 132 0.2247 0.2062 0.3030 8.28e-16 5bsk:A, 5bsk:B, 5bsk:C, 5bsk:D, 4kn6:A, 8tpy:A, 8tpy:B, 8tpy:C, 8tpy:D
17 2vfa:B 205 176 0.2640 0.2293 0.2670 1.25e-14 2vfa:A
18 2jbh:B 213 155 0.2360 0.1972 0.2710 1.76e-14 2jbh:A
19 1bzy:A 214 150 0.2247 0.1869 0.2667 2.59e-14 6bnj:A, 6bnj:B, 6bnj:C, 6bnj:D, 5brn:A, 5brn:C, 5brn:D, 1bzy:B, 1bzy:C, 1bzy:D, 1d6n:A, 1d6n:B, 3gep:A, 3gep:B, 3ggc:A, 3ggc:B, 3ggj:A, 3ggj:B, 5hia:A, 5hia:B, 5hia:C, 5hia:D, 1hmp:A, 1hmp:B, 4ijq:A, 4ijq:B, 4ijq:C, 4ijq:D, 4rab:A, 4rab:B, 4rab:C, 4rab:D, 4rac:A, 4rac:B, 4rac:C, 4rac:D, 4rad:A, 4rad:B, 4rad:C, 4rad:D, 4rad:E, 4rad:F, 4rad:G, 4rad:H, 4ran:A, 4ran:B, 4ran:C, 4ran:D, 4rao:A, 4rao:B, 4rao:C, 4rao:D, 4raq:A, 4raq:B, 4raq:C, 4raq:D, 7san:A, 7san:B, 7san:C, 7san:D, 8tpv:A, 8tpv:B, 8tpv:C, 8tpv:D, 5w8v:A, 5w8v:B, 5w8v:C, 5w8v:D
20 6bo7:A 220 178 0.2697 0.2182 0.2697 2.56e-12 6bo7:B, 6bo7:C, 6bo7:D, 6bo7:E, 6bo7:F, 6bo7:G, 6bo7:H, 6bo7:I, 6bo7:J, 6bo7:K, 6bo7:L
21 3ozf:B 234 191 0.3146 0.2393 0.2932 4.25e-11 1cjb:A, 1cjb:B, 1cjb:C, 1cjb:D, 3ozf:A, 3ozf:C, 3ozf:D, 3ozg:A, 3ozg:B, 3ozg:C, 3ozg:D, 7tux:A, 7tux:B, 7tux:C, 7tux:D
22 1fsg:A 233 94 0.1573 0.1202 0.2979 1.09e-09 1dbr:A, 1dbr:B, 1dbr:D, 1fsg:C, 1qk3:A, 1qk3:B, 1qk3:C, 1qk3:D, 1qk4:A, 1qk4:B, 1qk4:C, 1qk4:D, 1qk5:A, 1qk5:B
23 5esw:A 190 183 0.2584 0.2421 0.2514 3.82e-09 5esx:A, 5esx:B
24 4p86:A 177 63 0.1180 0.1186 0.3333 0.001 4p86:B, 4p86:C, 4p86:D
25 4zfn:B 177 49 0.1011 0.1017 0.3673 0.004 5bqp:A, 5bqp:B, 5bqp:C, 5bqp:D, 4z1o:A, 4z1o:B, 4zfn:A
26 2igb:B 173 59 0.1067 0.1098 0.3220 0.007 2igb:A, 4p83:A, 4p83:B, 4p83:C, 4p83:D, 1xz8:A, 1xz8:B, 1xzn:A, 1xzn:B
27 5iao:A 171 57 0.0955 0.0994 0.2982 0.012 5iao:C, 5iao:F
28 3db6:A 287 64 0.1236 0.0767 0.3438 0.34 3d5w:A, 3d5x:A, 3dbe:A
29 5yw5:A 178 132 0.1629 0.1629 0.2197 0.97 5yw5:B, 5yw5:C, 5yw5:D
30 4trb:B 209 146 0.2079 0.1770 0.2534 2.4 4trc:A, 4trc:B, 4ts5:A, 4ts5:B, 4ts7:A, 4ts7:B
31 6nfe:B 299 82 0.1236 0.0736 0.2683 3.5 6nfe:A
32 7lrd:A 512 65 0.0899 0.0312 0.2462 5.6 7lrd:C, 7lre:A, 7lre:B
33 1dl5:A 317 57 0.0843 0.0473 0.2632 6.3 1dl5:B
34 8gy3:C 732 39 0.0674 0.0164 0.3077 6.5
35 5zeb:e 198 40 0.0843 0.0758 0.3750 6.5 6dzi:m, 6dzk:E, 8fr8:f, 7kgb:e, 7msc:e, 7msh:e, 7msm:e, 7msz:e, 7mt2:e, 7mt3:e, 7mt7:e, 5o5j:E, 5o61:BE, 7sfr:e, 5v93:e, 8v9j:e, 8v9k:e, 8v9l:e, 8whx:f, 8wi7:f, 8wi9:f, 8wib:f, 8wid:f, 8wif:f, 5xyu:E, 5zep:e, 5zeu:e
36 3jsz:A 520 99 0.1461 0.0500 0.2626 6.9 3jt1:A, 2wzg:A
37 6wn8:E 210 52 0.0899 0.0762 0.3077 8.5 6wn8:F, 6wn8:A, 6wn8:B
38 3db8:A 261 63 0.1124 0.0766 0.3175 8.6 3dbc:A, 3dbd:A, 3dbf:A
39 8crx:E 179 40 0.0899 0.0894 0.4000 8.8 8cvo:E, 8cwo:E
40 7eg0:B 567 65 0.0899 0.0282 0.2462 9.2 7eg0:D, 7eg1:B, 7eg1:D, 7eg4:D, 7eg4:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218