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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NYEELFQTHKTPFYLYDFDKIKQAFLNYKEAFKGRKSLICYALKANSNLSILSLLAHLESGADCVSIGEIQRALKAGIKP
YRIVFSGVGKSAFEIEQALKLNILFLNVESFMELKTIETIAQSLGIKARISIRINPNIDAKTHPYISTGLKENKFGVGEK
EALEMFLWAKKSAFLEPVSVHFHIGSQLLDLEPIIEASQKVAKIAKSLIALGIDLRFFDVGGGIGVSYENEETIKLYDYA
QGILNALQGLDLTIICEPGRSIVAESGELITQVLYEKKNKRFVIVDAGMNDFLRPSLYHAKHAIRVITPSEISPCDVVGP
VCESSDTFLKDAHLPELEPGDKIAIEKVGAYGSSMASQYNSRPKLLELALEDKIRVIRKREALEDLWRLEEEGL

The query sequence (length=394) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3c5q:A 394 394 0.9975 0.9975 0.9975 0.0 2qgh:A
2 4xg1:B 418 396 0.4569 0.4306 0.4545 1.12e-111 4xg1:C, 4xg1:D
3 4xg1:A 393 399 0.4137 0.4148 0.4085 3.04e-84
4 1tuf:A 434 402 0.4061 0.3687 0.3980 9.08e-83 1tuf:B, 1twi:A, 1twi:B, 1twi:C, 1twi:D
5 2yxx:A 385 387 0.3756 0.3844 0.3824 7.73e-76
6 6n2a:A 422 394 0.3503 0.3270 0.3503 3.57e-69 6n2a:B, 6n2f:B, 6n2f:A
7 1knw:A 421 402 0.3147 0.2945 0.3085 3.17e-48 1ko0:A
8 1hkv:A 446 417 0.3046 0.2691 0.2878 7.59e-45 1hkv:B
9 5x7m:A 443 411 0.3122 0.2777 0.2993 1.05e-43 5x7m:B, 5x7n:A, 5x7n:B
10 7ru7:A 412 401 0.3122 0.2985 0.3067 1.19e-41 2j66:A
11 8d4i:A 462 423 0.2690 0.2294 0.2506 2.23e-31 8d2y:A, 8d4i:C, 8d5d:A, 8d5d:B, 8d5r:A, 8d5r:B, 8d88:A, 8d88:B
12 5gjo:A 385 360 0.2462 0.2519 0.2694 1.84e-28 5gjn:A, 5gjo:B, 5gjp:A
13 1f3t:B 381 362 0.2513 0.2598 0.2735 1.65e-27 1f3t:A, 1f3t:C, 1f3t:D, 1njj:A, 1njj:B, 1njj:C, 1njj:D, 1qu4:A, 1qu4:B, 1qu4:C, 1qu4:D, 1szr:C, 1szr:D, 1szr:A, 1szr:B, 2tod:A, 2tod:B, 2tod:C, 2tod:D
14 7kh2:D 415 410 0.2716 0.2578 0.2610 2.11e-25 7kh2:A, 7kh2:B, 7kh2:C
15 2oo0:A 419 375 0.2513 0.2363 0.2640 1.35e-24 5bwa:A, 7odc:A, 2on3:A, 2on3:B, 2oo0:B, 7s3f:A, 7s3f:B, 7s3g:A, 7s3g:B, 7u6p:A, 7u6p:B, 7u6u:A, 7u6u:B, 4zgy:A
16 6knh:C 384 371 0.2462 0.2526 0.2615 1.19e-23 6knh:A, 6knh:B, 6kni:A, 6kni:B, 6kni:C, 6knk:A, 6knk:B, 6knk:C
17 2nv9:B 372 335 0.2183 0.2312 0.2567 2.56e-20 2nv9:A, 2nv9:C, 2nv9:D, 2nv9:E, 2nv9:F, 2nv9:G, 2nv9:H, 2nva:A, 2nva:B, 2nva:C, 2nva:D, 2nva:E, 2nva:F, 2nva:G, 2nva:H
18 2plj:A 376 368 0.2157 0.2261 0.2310 1.47e-17 2plj:B, 2plk:A, 2plk:B
19 3n2o:A 630 291 0.1954 0.1222 0.2646 2.56e-16 3n2o:B, 3n2o:C, 3n2o:D
20 3nzq:A 628 286 0.1853 0.1162 0.2552 2.39e-15 3nzq:B
21 3nzp:B 591 248 0.1675 0.1117 0.2661 2.29e-09 3nzp:A
22 5gt1:A 153 71 0.0508 0.1307 0.2817 0.061
23 4lv4:A 320 69 0.0533 0.0656 0.3043 1.4
24 7e78:A 562 236 0.1523 0.1068 0.2542 1.9 7e78:C
25 4del:A 345 53 0.0431 0.0493 0.3208 2.8 4a22:A, 4a22:B, 4def:A, 3ekl:A, 3ekz:A, 3elf:A
26 4qvi:A 229 126 0.0761 0.1310 0.2381 4.5 7a5f:n, 7a5g:n, 7a5j:n, 5a9z:AC, 5aa0:AC, 2hw8:A, 5imq:Z, 5imr:Z, 7lh5:BC, 7lh5:DC, 6n1d:AL01, 6n1d:BL01, 5npm:A, 2om7:K, 5ot7:f, 6q95:A, 4qg3:A, 4reo:A, 4u1u:B5, 4u1v:B5, 4u20:B5, 4u24:B5, 4u25:B5, 4u26:B5, 4u27:B5, 3u4m:A, 3u56:A, 3umy:A, 5uq7:C, 5uq8:C, 4v4p:AC, 4v4x:BC, 4v4y:BC, 4v4z:BC, 4v51:BC, 4v51:DC, 4v5a:BC, 4v5a:DC, 4v5c:BC, 4v5c:DC, 4v5d:BC, 4v5d:DC, 4v5e:BC, 4v5e:DC, 4v5f:BC, 4v5f:DC, 4v5g:BC, 4v5g:DC, 4v5k:BC, 4v5k:DC, 4v5l:BC, 4v5m:BC, 4v5n:BC, 4v5p:BC, 4v5p:DC, 4v5q:BC, 4v5q:DC, 4v5r:BC, 4v5r:DC, 4v5s:BC, 4v5s:DC, 4v68:BC, 4v6a:BC, 4v6a:DC, 4v7l:BC, 4v7l:DC, 4v7m:BC, 4v7m:DC, 4v8j:BC, 4v8j:DC, 4v8o:BC, 4v8q:AC, 4v8u:BC, 4v8u:DC, 4v8y:By, 4v8y:CL, 4v90:BC, 4v97:BC, 4v97:DC, 4v9h:BC, 4v9j:BC, 4v9j:DC, 4v9k:BC, 4v9k:DC, 4v9l:BC, 4v9l:DC, 4v9m:BC, 4v9m:DC, 4w29:BC, 4w29:DC, 4wf1:B5, 4woi:B5, 1zho:A, 1zho:C, 1zho:E, 1zho:G, 5zlu:Y
27 7rd1:J 942 84 0.0533 0.0223 0.2500 4.5 7rd1:L, 7rd1:A, 7rd1:C, 7rd1:D, 7rd1:F, 7rd1:B, 7rd1:E, 7rd1:G, 7rd1:H, 7rd1:K, 7rd1:I
28 4b5n:A 354 134 0.0863 0.0960 0.2537 5.0 5k0r:A, 5k1k:A, 5k1m:A, 5k1q:A, 5k1u:A, 5k1w:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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