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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NWTPEAIRGLVDQEKGLLDPRIYADQSLYELELERVFGRSWLLLGHESHVPETGDFLATYMGEDPVVMVRQKDKSIKVFL
NQCRHRGMRICRSDAGNAKAFTCSYHGWAYDIAGKLVNVPFEKEAFFDKAEWGPLQARVATYKGLVFANWDVQAPDLETY
LGDARPYMDVMLDRTPAGTVAIGGMQKWVIPCNWKFAAEQFCSDMYHAGTTTHLSGILAGIPPEMDLSQAQIPTKGNQFR
AAWGGHGSGWYVDEPGSLLAVMGPKVTQYWTEGPAAELAEQRLGHTGMPVRRMVGQHMTIFPTCSFLPAMNQIRVWHPRG
PNEIEVWAFTLVDADAPAEIKEEYRRHNIRNFSAGGVFEQDDGENWVEIQKGLRGYKAKSQPFNAQMGLGRSQTGHPDFP
GNVGYVYAEEAARGMYHHWMRMMSEPSWATLKP

The query sequence (length=433) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5aeu:A 433 433 0.9885 0.9885 0.9885 0.0 5aeu:C, 5aeu:E, 5aeu:G, 5aew:A, 5aew:C, 5aew:E, 5aew:G, 5aew:I, 5aew:K, 5aew:M, 5aew:O, 5aew:Q, 5aew:S, 5aew:U, 5aew:W, 2xr8:A, 2xr8:C, 2xr8:E, 2xr8:G, 2xr8:I, 2xr8:K, 2xr8:M, 2xr8:O, 2xr8:Q, 2xr8:S, 2xr8:U, 2xr8:W, 2xrx:A, 2xrx:C, 2xrx:E, 2xrx:G, 2xrx:I, 2xrx:K, 2xrx:M, 2xrx:O, 2xrx:Q, 2xrx:S, 2xrx:U, 2xrx:W, 2xsh:A, 2xsh:C, 2xsh:E, 2xsh:G, 2xsh:I, 2xsh:K, 2xso:A, 2xso:C, 2xso:E, 2xso:G, 2xso:I, 2xso:K, 2xso:M, 2xso:O, 2xso:Q, 2xso:S, 2xso:U, 2xso:W, 2yfi:A, 2yfi:C, 2yfi:E, 2yfi:G, 2yfi:I, 2yfi:K, 2yfj:A, 2yfj:C, 2yfj:E, 2yfj:G, 2yfj:I, 2yfj:K, 2yfl:A, 2yfl:C, 2yfl:E, 2yfl:G, 2yfl:I, 2yfl:K
2 3gzx:A 440 442 0.7598 0.7477 0.7443 0.0 3gzy:A
3 1wql:A 436 436 0.7367 0.7317 0.7317 0.0
4 1uli:C 425 432 0.6859 0.6988 0.6875 0.0 1uli:A, 1uli:E, 1ulj:A, 1ulj:C, 1ulj:E
5 3en1:A 424 427 0.6790 0.6934 0.6885 0.0 3eqq:A
6 2gbw:A 449 435 0.3949 0.3808 0.3931 1.82e-98 2ckf:A, 2gbw:C, 2gbw:E, 2gbx:A, 2gbx:C, 2gbx:E
7 2ckf:E 433 428 0.3764 0.3764 0.3808 1.24e-92 2ckf:C
8 2b1x:A 441 423 0.3603 0.3537 0.3688 3.20e-78 2b1x:C, 2b1x:E, 2b24:A, 2b24:C, 2b24:E
9 5xbp:A 444 431 0.3349 0.3266 0.3364 2.07e-72 5xbp:D, 5xbp:G
10 1eg9:A 447 445 0.3395 0.3289 0.3303 2.30e-70 4hjl:A, 4hkv:A, 2hmj:A, 2hmk:A, 2hml:A, 2hmm:A, 2hmn:A, 2hmo:A, 4hm0:A, 4hm1:A, 4hm2:A, 4hm3:A, 4hm4:A, 4hm5:A, 4hm6:A, 4hm7:A, 4hm8:A, 1ndo:A, 1ndo:C, 1ndo:E, 1o7g:A, 1o7h:A, 1o7m:A, 1o7n:A, 1o7p:A, 1o7w:A, 1uuv:A, 1uuw:A
11 2bmo:A 437 419 0.3164 0.3135 0.3270 2.21e-69 2bmq:A, 2bmr:A
12 7yls:B 436 390 0.2494 0.2477 0.2769 2.13e-37 8h2t:B, 8h2t:D, 8h2t:G
13 7c8z:A 383 420 0.2841 0.3211 0.2929 1.29e-34 7c8z:C, 7c8z:E, 7c8z:G
14 7q05:E 409 366 0.2379 0.2518 0.2814 4.83e-33 7q04:D, 7q04:E, 7q04:F, 7q05:D, 7q05:F, 7q06:D, 7q06:E, 7q06:F, 7vju:A, 7vju:C, 7vju:E
15 4qur:A 415 341 0.1986 0.2072 0.2522 6.89e-22 5hl4:A, 4qup:A, 4quq:A, 3vca:A, 3vcp:A
16 3n0q:A 402 343 0.1940 0.2090 0.2449 3.11e-21
17 6y9c:A 365 194 0.1201 0.1425 0.2680 3.41e-18 6y8s:A, 6y9d:A, 6y9d:B, 6y9d:C, 6y9d:D, 6y9d:E, 6y9d:F, 6y9d:G, 6y9d:H, 6y9d:I, 6y9d:J, 6y9d:K, 6y9d:L, 6zgp:A, 6zgp:B, 6zgp:C, 6zgp:D, 6zgp:E, 6zgp:F, 6zgp:G, 6zgp:H, 6zgp:I, 6zgp:J, 6zgp:K, 6zgp:L
18 6y8j:A 343 217 0.1339 0.1691 0.2673 3.78e-18
19 6wn3:B 328 51 0.0416 0.0549 0.3529 9.56e-05 7szh:A, 7szh:B, 7szh:C, 6wn3:A, 6wn3:C, 6wnb:A, 6wnb:B, 6wnb:C
20 3gcf:A 367 74 0.0577 0.0681 0.3378 1.26e-04 3gcf:B, 3gcf:C, 3gcf:D, 3gcf:E, 3gcf:F, 3gcf:G, 3gcf:H, 3gcf:I, 3gcf:J, 3gcf:K, 3gcf:L, 3gcf:M, 3gcf:N, 3gcf:O
21 7sze:B 329 50 0.0416 0.0547 0.3600 1.75e-04 7sze:A, 7sze:C, 7szf:A, 7szf:B, 7szf:C, 7szg:A, 7szg:B, 7szg:C, 6wnc:A, 6wnc:B, 6wnc:C, 6wnd:A, 6wnd:B, 6wnd:C
22 3gkq:A 374 172 0.0993 0.1150 0.2500 4.95e-04 3gkq:B, 3gkq:C, 3gkq:D, 3gkq:E, 3gkq:F
23 7fhr:A 437 160 0.0947 0.0938 0.2562 0.002
24 1z01:A 427 55 0.0393 0.0398 0.3091 0.007 1z01:B, 1z01:C, 1z01:D, 1z01:E, 1z01:F, 1z02:A, 1z02:B, 1z02:C, 1z02:D, 1z02:E, 1z02:F, 1z03:A, 1z03:B, 1z03:C, 1z03:D, 1z03:E, 1z03:F
25 7v28:B 425 95 0.0624 0.0635 0.2842 0.014 7fjl:A, 7fjl:B, 7fjl:C, 7fjl:D, 7fjl:E, 7fjl:F, 7v25:B, 7v25:A, 7v25:C, 7v25:D, 7v25:E, 7v25:F, 7v28:A, 7v28:C, 7v28:D, 7v28:E, 7v28:F
26 2de6:B 390 172 0.0878 0.0974 0.2209 0.044 7bug:A, 7bug:B, 7bug:C, 7bui:A, 7bui:B, 7bui:C, 2de5:A, 2de5:B, 2de5:C, 2de6:A, 2de6:C, 2de7:A, 2de7:B, 2de7:C, 6ll0:A, 6ll0:B, 6ll0:C, 6ll1:A, 6ll1:B, 6ll1:C, 6ll4:A, 6ll4:B, 6ll4:C, 6llf:A, 6llf:B, 6llf:C, 6llh:A, 6llh:B, 6llh:C, 6llk:A, 6llm:A, 4nb8:A, 4nb8:B, 4nb8:C, 4nb9:A, 4nb9:B, 4nb9:C, 4nba:A, 4nba:B, 4nba:C, 4nbb:A, 4nbb:B, 4nbb:C, 4nbc:A, 4nbc:B, 4nbc:C, 4nbd:A, 4nbd:B, 4nbd:C, 4nbe:A, 4nbe:B, 4nbe:C, 4nbf:A, 4nbf:B, 4nbf:C, 4nbg:A, 4nbg:B, 4nbg:C, 4nbh:A, 4nbh:B, 4nbh:C, 3vmg:A, 3vmg:B, 3vmg:C, 3vmh:A, 3vmh:B, 3vmh:C, 3vmi:A, 3vmi:B, 3vmi:C, 1ww9:A
27 6icl:A 338 68 0.0577 0.0740 0.3676 0.064
28 4qdc:A 369 87 0.0485 0.0569 0.2414 0.065 4qdd:A, 4qdf:A
29 6rqf:L 179 88 0.0647 0.1564 0.3182 0.11 7qrm:D, 7qrm:L, 1rfs:A, 6rqf:D, 7zyv:D, 7zyv:L
30 6vsh:C 320 64 0.0416 0.0563 0.2812 0.16 3gke:C, 3gl0:C, 3gl2:C
31 3gob:A 342 64 0.0416 0.0526 0.2812 0.19 3gb4:A, 3gb4:B, 3gb4:C, 3gke:A, 3gke:B, 3gl0:A, 3gl0:B, 3gl2:A, 3gl2:B, 3gob:B, 3gob:C, 3gte:A, 3gte:B, 3gte:C, 3gts:A, 3gts:B, 3gts:C, 6vsh:A, 6vsh:B
32 6icn:A 344 64 0.0393 0.0494 0.2656 0.62 6ick:A, 6ick:B, 6ick:C, 6icm:A, 6icm:B, 6icm:C, 6icn:B, 6icn:C, 6ico:A, 6ico:B, 6ico:C, 6icp:A, 6icp:B, 6icp:C, 6icq:A, 6icq:B, 6icq:C
33 4h44:D 166 86 0.0647 0.1687 0.3256 0.69 4ogq:D, 2zt9:D
34 4qdf:B 357 87 0.0462 0.0560 0.2299 0.70
35 4u03:A 389 145 0.0693 0.0771 0.2069 0.97 4txy:A, 4txz:A, 4ty0:A, 4u03:B, 4u0m:A, 4u0m:B, 4u0n:A, 4u0n:B, 4xj4:A
36 7r0w:D 169 118 0.0808 0.2071 0.2966 1.1 7r0w:L, 7zxy:D, 7zxy:L
37 2i7f:A 102 60 0.0393 0.1667 0.2833 2.1 2i7f:B
38 8bpx:AD 196 48 0.0393 0.0867 0.3542 2.3 8bel:D, 8bel:N, 8bpx:BD, 8bq5:AD, 8bq5:BD, 8bq6:AD, 8bq6:BD
39 3cx5:P 185 51 0.0393 0.0919 0.3333 2.8 3cx5:E, 3cxh:P, 3cxh:E, 8e7s:C, 8e7s:c, 8ec0:C, 8ec0:c, 1ezv:E, 6giq:E, 6giq:P, 6hu9:E, 6hu9:P, 2ibz:E, 1kb9:E, 1kyo:E, 1kyo:P, 1p84:E, 4pd4:E, 6t0b:E, 6t0b:P, 6t15:E, 6t15:P, 6ymx:E, 6ymx:P
40 8iuf:QE 231 43 0.0346 0.0649 0.3488 3.1 8iuf:Qe, 8iuj:QE, 8iuj:Qe
41 8ibd:AE 109 43 0.0300 0.1193 0.3023 4.2 8ibg:AE
42 3azc:A 133 75 0.0600 0.1955 0.3467 5.8
43 2d2c:D 168 77 0.0554 0.1429 0.3117 6.8 2d2c:Q, 2e74:D, 2e75:D, 2e76:D, 4h0l:D, 4h13:D, 4i7z:D, 4pv1:D, 1vf5:D, 1vf5:Q
44 7llk:G 131 49 0.0393 0.1298 0.3469 7.4 7llk:C, 7llk:K
45 1agn:A 373 56 0.0485 0.0563 0.3750 8.9 1agn:B, 1agn:C, 1agn:D, 1d1s:A, 1d1s:B, 1d1s:C, 1d1s:D, 1d1t:A, 1d1t:B, 1d1t:C, 1d1t:D
46 2yiu:F 174 55 0.0346 0.0862 0.2727 9.3 2yiu:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218