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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NWIGDENLTGNAEAPAKDDVVPDKNQFRYQKEELAAFCHFGPNTFNEIEWGEHYGNQKPSEIFTLKNDFDAETLVKTLKD
AGFKKLIVTAKHHDGFCIWDSEHTEYDVKASGYKNKNGESDILAEISKACTDQNMDMGLYLSPWDIHEPSYGYKDEHGNP
TTPDKDAKDYNEFYNNQLEEILGNPKYGNDGHFVEVWMAGAKGSGANAQEYDFKKWFKTIQDNEGKAAGYDADCMLFGAE
AYTTVRWIGNELGIAGKDTWSKSKVDKDKNTINSNKQGNATVGFEDGDQWTVPEADARITSGWFWGTKKNTPKTMEELSD
MYFNSVGHNATLLLNVPPNNQGTVDKAILDRVTEFGNNIKATFKTNLAKAEGASVKVSEVRGGAKEYKPGNMIDDNDETY
WATSDGKKSGEILIDLGKETKFDVVSIEEAIQNGQRINNYKVEYRNGDSGTWTLLEEGKTIGAKRLCRTSETTARQIKIT
VGTCDGKVPMISEIGVYKSTEDMEKP

The query sequence (length=506) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6tr4:A 506 506 1.0000 1.0000 1.0000 0.0 6tr3:A, 6tr4:B
2 6org:A 450 483 0.3775 0.4244 0.3954 8.86e-111 6or4:A, 6or4:B, 6orf:A, 6orf:B, 6org:B, 6orh:A, 6orh:B
3 4oue:A 459 490 0.3182 0.3508 0.3286 7.49e-76 4oue:B, 4ozo:A, 4ozo:B
4 8ayr:A 677 496 0.3202 0.2393 0.3266 2.40e-72 8ayr:B
5 3ues:B 458 493 0.2885 0.3188 0.2961 1.37e-62 3mo4:A, 3ues:A, 3uet:A, 3uet:B
6 5k9h:A 554 503 0.3063 0.2798 0.3082 1.22e-59
7 4pee:C 446 194 0.1166 0.1323 0.3041 2.11e-15 5hdr:A, 5hdr:B, 5hdr:C, 5hdr:D, 6hzy:A, 6hzy:B, 5i5r:A, 5i5r:B, 5i5r:C, 5i5r:D, 4j28:A, 4j28:B, 4jfs:A, 4jfs:B, 4jft:A, 4jft:B, 4jfu:A, 4jfu:B, 4jfv:A, 4jfv:B, 4jfv:C, 4jfv:D, 4jfw:A, 4jfw:B, 4jfw:C, 4jfw:D, 4jl1:A, 4jl1:B, 4jl2:A, 4jl2:B, 4pcs:A, 4pcs:B, 4pcs:C, 4pcs:D, 4pct:A, 4pct:B, 4pct:C, 4pct:D, 4pee:A, 4pee:B, 4pee:D, 4wsj:A, 4wsj:B, 4wsj:C, 4wsj:D, 4wsk:A, 4wsk:B, 4wsk:C, 2wvs:A, 2wvs:B, 2wvs:C, 2wvs:D, 2wvt:A, 2wvt:B, 2wvu:A, 2wvu:B, 2wvu:C, 2wvu:D, 2xib:A, 2xib:B, 2xib:C, 2xib:D, 2xii:A, 2xii:B
8 6o1j:A 329 131 0.0870 0.1337 0.3359 3.39e-11 6o1a:A, 6o1a:B, 6o1a:C, 6o1a:D, 6o1c:A, 6o1c:B, 6o1c:C, 6o1c:D, 6o1c:E, 6o1c:F, 6o1c:G, 6o1c:H, 6o1j:B, 6o1j:C, 6o1j:D, 6o1j:E, 6o1j:F, 6o1j:G, 6o1j:H, 6ohe:A, 6ohe:B, 6ohe:C, 6ohe:D
9 6gn6:F 428 280 0.1344 0.1589 0.2429 9.53e-10 6gn6:A, 6gn6:C, 6gn6:E, 6gn6:D, 6gn6:B
10 8p1s:A 335 85 0.0632 0.0955 0.3765 4.81e-09 8p1s:B, 8p1s:C, 8p1s:D, 8p1s:E, 8p1s:F
11 2zx6:A 442 93 0.0573 0.0656 0.3118 7.40e-09 1hl9:A, 1hl9:B, 1odu:A, 1odu:B, 2wsp:A, 2wsp:B, 2zwz:A, 2zwz:B, 2zx5:A, 2zx5:B, 2zx6:B, 2zx7:A, 2zx7:B, 2zx8:A, 2zx8:B, 2zx9:A, 2zx9:B, 2zxa:A, 2zxa:B, 2zxb:A, 2zxb:B, 2zxd:A, 2zxd:B
12 7pm4:A 431 107 0.0593 0.0696 0.2804 3.13e-04 7pm4:B, 7pm4:C, 7pm4:D
13 7xsh:A 548 349 0.1462 0.1350 0.2120 0.002 7xsh:B
14 4ni3:B 583 40 0.0316 0.0274 0.4000 0.003 4ni3:A, 4psr:A, 4psr:B
15 7lnp:A 565 72 0.0375 0.0336 0.2639 0.014 7ljj:A, 7lk7:A, 7lnp:C, 7lnp:D, 7lnp:E
16 8olu:L 202 45 0.0316 0.0792 0.3556 0.41 8olu:Z, 6qm7:L, 6qm7:Z, 6tcz:L, 6tcz:l, 6td5:L, 6td5:l, 7zyj:L, 7zyj:l
17 1r9d:A 786 81 0.0593 0.0382 0.3704 0.75 1r9d:B
18 4q5r:A 202 40 0.0217 0.0545 0.2750 3.7 4q5r:C, 4q5r:D, 4q5r:B, 4q5r:F, 4q5r:E
19 1tvg:A 136 59 0.0336 0.1250 0.2881 4.2
20 7d9x:A 336 93 0.0455 0.0685 0.2473 5.5 7d9x:C
21 6n7p:G 239 48 0.0277 0.0586 0.2917 8.2 6g90:G, 6n7r:G, 6n7x:G, 7oqc:G, 7oqe:G, 8w2o:G, 5zwn:W
22 7nwf:A 432 189 0.0791 0.0926 0.2116 8.5 6t8k:A, 6t8k:B, 6t8l:A, 6tcw:A
23 6tcv:B 397 115 0.0534 0.0680 0.2348 9.8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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