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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NWEHLLSLKRQGDTAKRLRIEQDDTRLGFEVDYDRIIFSAPFRSLQDKTQVIPLDFVHTRLTHSLEVSVVGRSLGRMVGK
KLLEKYPHLEQVYGYKFNDFGAIVAAAALAHDIGNPPFGHSGEKAIGEFFKNGYGKRYKDSLTAKEYQDLIKFEGNANGF
KVLSQSKPGAQGGLRLSYATLGAFMKYPKESLPHKPSDHIADKKYGFFQSERALFEDVAQELGLLKRSDVSWSRHPLAYL
VEAADDICYTIIDFEDGINLGLIPEEYALEYMVKLVGQTIDRNKYNALQETSDRVSYLRALAIGTLINESVDTFMKYEEE
ILAGTFDQSLIDKSNYQAQITDIINLSIERIYNSREVIEKEIAGYEILSTLLEARCRALDNNDTHYNQLIQQLLAPNEKS
LYENLIQICAEVSTMTDGKALRNYKKIKGL

The query sequence (length=430) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7tu2:A 434 436 0.9907 0.9816 0.9771 0.0 7tu0:A, 7tu0:B, 7tu0:C, 7tu2:B, 7tu2:C, 7tu3:A, 7tu3:B, 7tu3:C, 7tu4:A, 7tu4:B, 7tu4:C, 7tu5:A, 7tu5:B, 7tu5:C, 7tu5:D, 7tu5:E, 7tu5:F, 7tu6:A, 7tu6:B, 7tu6:C, 7tu6:D, 7tu6:E, 7tu6:F, 7tu7:A, 7tu7:B, 7tu7:C, 7tu7:D, 7tu7:E, 7tu7:F, 7tu8:A, 7tu8:B, 7tu8:C, 7tu8:D, 7tu8:E, 7tu8:F
2 6oiw:A 504 441 0.2977 0.2540 0.2902 2.79e-45 6oi7:A, 6oi7:B, 6oi7:C, 6oi7:D, 6oi7:E, 6oi7:F, 6oiv:A, 6oiv:B, 6oiv:C, 6oiv:D, 6oiv:E, 6oiv:F, 6oiw:B, 6oiw:C, 6oiw:D, 6oiw:E, 6oiw:F, 6oiy:A, 6oiy:B, 6oiy:C, 6oiy:D, 6oiy:E, 6oiy:F, 4x9e:A, 4x9e:B
3 6oix:C 478 424 0.2953 0.2657 0.2995 1.25e-44 6oix:A, 6oix:B, 6oix:D, 6oix:E, 6oix:F, 7u66:A, 7u66:B, 7u66:C, 7u66:D, 7u66:E, 7u66:F, 7u67:A, 7u67:D, 7u67:C, 7u67:B, 7u67:F, 7u67:E
4 2dqb:C 364 430 0.2558 0.3022 0.2558 2.82e-18 2dqb:A, 2dqb:B, 2dqb:D, 2dqb:E, 2dqb:F
5 2hek:A 369 95 0.0698 0.0813 0.3158 0.058 2hek:B
6 4lrl:C 455 67 0.0442 0.0418 0.2836 0.61 3irh:A, 3irh:B, 3irh:C, 3irh:D, 4lrl:A, 4lrl:B, 4lrl:D, 2o6i:A, 2o6i:B
7 4v8p:BC 409 55 0.0465 0.0489 0.3636 0.66 4v8p:CC, 4v8p:EC, 4v8p:GC
8 2q14:C 406 70 0.0488 0.0517 0.3000 0.78 2q14:A, 2q14:B, 2q14:D, 2q14:E, 2q14:F, 2q14:G, 2q14:H
9 4v37:A 495 75 0.0558 0.0485 0.3200 1.1 4a0m:A, 4a0m:B, 4a0m:C, 4a0m:D, 4v37:B, 4v37:C, 4v37:D
10 6brh:B 502 63 0.0535 0.0458 0.3651 1.4 6brg:A, 6brg:B, 6brg:C, 6brg:D, 6brh:A, 6brk:A
11 4e4f:B 381 83 0.0558 0.0630 0.2892 1.4 4e4f:C, 4il2:A, 4il2:C, 4il2:D
12 4mz7:B 493 63 0.0512 0.0446 0.3492 3.0 7a5y:A, 7a5y:B, 7a5y:C, 7a5y:D, 7a5y:E, 7a5y:F, 7a5y:G, 7a5y:H, 5ao0:A, 5ao0:B, 5ao1:A, 5ao1:B, 5ao1:C, 5ao1:D, 5ao2:A, 5ao2:B, 5ao2:C, 5ao2:D, 5ao3:A, 5ao3:C, 5ao3:B, 5ao3:D, 5ao4:A, 5ao4:B, 4bzb:A, 4bzb:C, 4bzb:D, 4bzb:B, 4bzc:A, 4bzc:C, 4bzc:D, 4bzc:B, 6cm2:D, 6cm2:A, 6cm2:B, 6cm2:C, 8d94:A, 8d94:D, 8d94:B, 8d94:C, 8d9j:A, 8d9j:D, 8d9j:B, 8d9j:C, 6dw3:D, 6dw3:C, 6dw3:B, 6dw3:A, 6dw4:D, 6dw4:C, 6dw4:B, 6dw4:A, 6dw5:A, 6dw5:D, 6dw5:B, 6dw5:C, 6dw7:A, 6dw7:B, 6dw7:C, 6dw7:D, 6dwd:D, 6dwd:A, 6dwd:C, 6dwd:B, 6dwj:D, 6dwj:A, 6dwj:C, 6dwj:B, 6dwk:A, 6dwk:D, 6dwk:B, 6dwk:C, 8gb1:A, 8gb1:B, 8gb1:C, 8gb1:D, 8gb2:D, 8gb2:A, 8gb2:B, 8gb2:C, 7ltt:A, 7ltt:D, 7ltt:B, 7ltt:C, 7lu5:A, 7lu5:D, 7lu5:C, 7lu5:B, 7lu5:E, 7lu5:H, 7lu5:F, 7lu5:G, 7lu5:I, 7lu5:L, 7lu5:K, 7lu5:J, 7lu5:M, 7lu5:P, 7lu5:O, 7lu5:N, 4mz7:A, 4q7h:A, 4q7h:B, 4q7h:C, 4q7h:D, 4qfx:A, 4qfx:D, 4qfx:B, 4qfx:C, 4qfy:A, 4qfy:D, 4qfy:B, 4qfy:C, 4qfz:A, 4qfz:D, 4qfz:B, 4qfz:C, 4qg0:A, 4qg0:D, 4qg0:B, 4qg0:C, 4qg1:A, 4qg1:B, 4qg1:C, 4qg1:D, 4qg2:A, 4qg2:D, 4qg2:B, 4qg2:C, 4qg4:A, 4qg4:D, 4qg4:B, 4qg4:C, 8qxj:A, 8qxj:B, 8qxj:C, 8qxj:D, 8qxk:A, 8qxk:B, 8qxk:C, 8qxk:D, 8qxl:A, 8qxl:B, 8qxl:C, 8qxl:D, 8qxm:A, 8qxm:C, 8qxm:B, 8qxm:D, 8qxn:A, 8qxn:B, 8qxn:C, 8qxn:D, 8qxo:A, 8qxo:B, 8qxo:D, 8qxo:C, 4rxo:A, 4rxo:B, 4rxo:C, 4rxo:D, 4rxp:A, 4rxp:B, 4rxq:A, 4rxq:B, 4rxr:A, 4rxr:B, 4rxs:A, 4rxs:B, 7s2y:A, 7s2y:B, 7s2y:C, 7s2y:D, 8tdv:A, 8tdv:B, 8tdw:A, 8tdw:B, 4tnp:A, 4tnp:C, 4tnp:D, 4tnp:B, 4tnq:A, 4tnq:D, 4tnq:C, 4tnq:B, 4tnr:D, 4tnr:A, 4tnr:C, 4tnr:B, 4tnx:A, 4tnx:C, 4tnx:D, 4tnx:B, 4tny:A, 4tny:C, 4tny:B, 4tny:D, 4tnz:C, 4tnz:B, 4tnz:A, 4tnz:D, 4to0:A, 4to0:D, 4to0:C, 4to0:B, 4to1:A, 4to1:B, 4to1:C, 4to1:D, 4to2:A, 4to2:D, 4to2:B, 4to2:C, 4to3:A, 4to3:D, 4to3:B, 4to3:C, 4to4:A, 4to4:D, 4to4:B, 4to4:C, 4to5:A, 4to5:D, 4to5:C, 4to5:B, 4to6:A, 4to6:D, 4to6:B, 4to6:C, 6tx0:A, 6tx0:B, 6txa:A, 6txa:B, 6txa:D, 6txa:C, 6txa:E, 6txa:F, 6txa:H, 6txa:G, 6txa:I, 6txa:L, 6txa:J, 6txa:K, 6txa:M, 6txa:N, 6txa:P, 6txa:O, 6txc:A, 6txc:B, 6txc:D, 6txc:C, 6txc:E, 6txc:F, 6txc:H, 6txc:G, 6txc:I, 6txc:J, 6txc:L, 6txc:K, 6txc:M, 6txc:N, 6txc:P, 6txc:O, 6txe:A, 6txe:B, 6txe:C, 6txe:D, 6txe:E, 6txe:F, 6txe:G, 6txe:H, 6txe:I, 6txe:J, 6txe:K, 6txe:L, 6txe:M, 6txe:N, 6txe:P, 6txe:O, 6txf:A, 6txf:B, 3u1n:A, 3u1n:B, 3u1n:C, 3u1n:D, 6u6x:A, 6u6x:D, 6u6y:A, 6u6y:D, 6u6y:B, 6u6y:C, 6u6z:A, 6u6z:D, 6u6z:B, 6u6z:C, 7ujn:A, 7ujn:B, 7ujn:C, 7ujn:D, 6xu1:A, 6xu1:B, 6xu1:C, 6xu1:D, 6xu1:E, 6xu1:F, 6xu1:G, 6xu1:H, 6yom:A, 6yom:B, 4zwe:A, 4zwe:C, 4zwe:D, 4zwe:B, 4zwg:A, 4zwg:D, 4zwg:B, 4zwg:C
13 5ao4:C 389 64 0.0488 0.0540 0.3281 3.1 5ao4:D, 6u6x:B
14 6u6x:C 376 63 0.0512 0.0585 0.3492 3.5
15 6oxl:B 564 129 0.0767 0.0585 0.2558 3.6 7rwc:B
16 8xw0:B 696 55 0.0372 0.0230 0.2909 4.8 8xw0:A
17 6gaw:B2 179 34 0.0326 0.0782 0.4118 4.9 5aj4:B2, 6gb2:B2, 7nqh:B2, 7nql:B2, 7nsh:B2, 7nsi:B2, 7nsj:B2, 8oin:BF, 8oiq:BF, 4v19:2, 6ydp:B2, 6ydw:B2
18 8ah3:A 375 53 0.0488 0.0560 0.3962 6.0
19 8squ:A 372 46 0.0326 0.0376 0.3043 6.9
20 5fui:A 124 45 0.0279 0.0968 0.2667 7.3
21 7b0n:G 694 95 0.0581 0.0360 0.2632 7.3 6gcs:A, 7o6y:A, 7o71:A, 6rfq:A, 6rfr:A, 6rfs:A, 6y79:A, 6yj4:G
22 8spo:M 394 53 0.0372 0.0406 0.3019 7.8 8spo:E
23 8fkp:SA 331 55 0.0395 0.0514 0.3091 8.2 8fkq:SA, 8fkr:SA, 8fks:SA
24 7f5s:LC 368 55 0.0395 0.0462 0.3091 8.3 7a01:t2, 8a3d:F, 5aj0:AC, 8b5l:C, 8b6c:C, 9bdl:AL04, 9bdn:AL04, 9bdp:AL04, 7bhp:LC, 8bhf:l3, 8bpo:C2, 8btk:BC, 7cpu:LC, 7cpv:LC, 4d5y:C, 4d67:C, 6d90:C, 6d9j:C, 9f1b:BC, 9f1c:BC, 9f1d:BC, 8fkt:SA, 8fku:SA, 8fkv:SA, 8fkw:SA, 8fkx:SA, 8fky:SA, 8fkz:SA, 8fl2:SA, 8fl3:SA, 8fl4:SA, 8fl6:SA, 8fl7:SA, 8fl9:SA, 8fla:SA, 8flb:SA, 8flc:SA, 8fld:SA, 8fle:SA, 8flf:SA, 9fpz:LC, 9fq0:LC, 6frk:C, 6ftg:C, 6fti:C, 6ftj:C, 8g5y:LC, 8g5z:LC, 8g60:LC, 8g61:LC, 8g6j:LC, 8glp:LC, 6gz3:AC, 6gz4:AC, 6gz5:AC, 6hcf:C3, 6hcj:C3, 6hcm:C3, 6hcq:C3, 8idt:D, 8idy:D, 8ie3:D, 8ifd:1F, 8ife:1F, 8ine:D, 8inf:D, 8ink:D, 6ip5:1F, 6ip6:1F, 6ip8:1F, 8ipd:D, 8ipx:D, 8ipy:D, 8ir1:D, 8ir3:D, 3j7o:C, 3j7p:C, 3j7q:C, 3j7r:C, 3j92:C, 3jag:C, 3jah:C, 3jai:C, 3jaj:C, 3jan:C, 8jdj:I, 8jdk:I, 8jdl:I, 8jdm:I, 8k2c:LC, 5lks:LC, 6lqm:D, 6lsr:D, 6lss:D, 7ls1:F2, 7ls2:F2, 6lu8:D, 5lzs:C, 5lzt:C, 5lzu:C, 5lzv:C, 5lzw:C, 5lzx:C, 5lzy:C, 5lzz:C, 7mdz:C, 6mtb:C, 6mtc:C, 6mtd:C, 6mte:C, 7nfx:C, 7nwg:C3, 7nwh:C, 7nwi:C, 7o7y:BC, 7o7z:BC, 7o80:BC, 7o81:BC, 7obr:C, 8ohd:LC, 8oj0:LC, 8oj5:LC, 8oj8:LC, 6ole:C, 6olf:C, 6olg:AC, 6oli:C, 6olz:AC, 6om0:C, 6om7:C, 7ow7:F, 7oyd:C, 8p2k:BC, 6p5i:AC, 6p5j:AC, 6p5k:AC, 6p5n:AC, 8q7z:BC, 8q87:BC, 8qfd:C, 7qgg:C, 8qoi:LC, 7qvp:MC, 7qvp:LC, 7qwq:C, 7qwr:C, 7qws:C, 6qzp:LC, 6r5q:C, 6r6g:C, 6r6p:C, 6r7q:C, 8rjb:C, 8rjc:C, 8rjd:C, 8scb:C, 6sgc:C2, 6swa:C, 5t2c:F, 6t59:C3, 7tm3:C, 7toq:AL04, 7tor:AL04, 7tut:C, 7ucj:C, 7uck:C, 4ug0:LC, 4ujc:BC, 4ujd:AC, 4uje:CC, 4v5z:Bc, 4v6x:CC, 6w6l:C, 6xa1:LC, 7xnx:LC, 7xny:LC, 8xsx:LC, 8xsy:LC, 8xsz:LC, 6y0g:LC, 8y0w:LC, 8y0x:LC, 6y2l:LC, 6y57:LC, 6y6x:LC, 8yoo:LC, 8yop:LC, 6z6l:LC, 6z6m:LC, 6z6n:LC, 7zjw:LF, 7zjx:LF, 6zm7:LC, 6zme:LC, 6zmi:LC, 6zmo:LC, 6zvk:t2
25 5xbl:A 1320 228 0.1302 0.0424 0.2456 8.6
26 8kag:B 1346 228 0.1302 0.0416 0.2456 8.9 8kah:F, 8kai:F, 8kaj:F, 8spq:A, 8sqh:A, 8srs:A, 8tzz:A, 8u3y:A, 6vpc:B, 7z4h:B, 7z4i:B, 7z4l:B, 4zt9:A
27 8ffi:A 419 46 0.0326 0.0334 0.3043 10.0 8ffi:E, 8ffi:I, 8ffi:M, 8i87:G, 8i87:O, 8i87:A, 8i87:C, 8j7s:B, 8j7s:F, 8j7s:J, 8j7s:N, 8jr8:B, 8jr8:D, 8oz6:A, 8oz6:C, 8oz6:E, 8oz6:G, 8ozd:A, 8ozd:C, 8oze:E, 8oze:G, 8ozf:A, 8ozf:C, 8ozf:F, 8ozf:H, 8ozg:A, 8ozg:C, 8ozg:F, 8ozg:H, 8ozi:A, 8ozi:C, 8ozi:E, 8ozi:G, 8sp0:A, 8sp0:E, 8sp3:A, 8sp3:E, 8spo:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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