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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELE
RQSLGENPSYKLLKKLDFGYCRLSLALPQLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICD
LVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVE
RPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK

The query sequence (length=290) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4yb6:A 296 296 1.0000 0.9797 0.9797 0.0 5ub9:A, 5ub9:B, 5ubg:A, 5ubg:B, 5ubh:A, 5ubh:B, 5ubi:A, 5ubi:B, 4yb5:A, 4yb5:E, 4yb5:B, 4yb5:C, 4yb5:F, 4yb5:D, 4yb6:E, 4yb6:B, 4yb6:C, 4yb6:F, 4yb6:D, 4yb7:B, 4yb7:C, 4yb7:D, 4yb7:E, 4yb7:I, 4yb7:K, 4yb7:A, 4yb7:F, 4yb7:G, 4yb7:H, 4yb7:J, 4yb7:L
2 1h3d:A 288 295 0.6655 0.6701 0.6542 6.64e-140 1q1k:A
3 7dah:C 288 296 0.6276 0.6319 0.6149 4.06e-125 7dah:F
4 2vd3:A 289 295 0.3310 0.3322 0.3254 4.29e-46 2vd3:B
5 5lht:A 284 289 0.3000 0.3063 0.3010 4.68e-31 5lhu:A, 1nh8:A, 5u99:A
6 6czm:E 342 322 0.3138 0.2661 0.2826 2.06e-28 6czm:A, 6czm:C, 6czm:D
7 6czm:F 315 311 0.2862 0.2635 0.2669 1.58e-19 6czm:B
8 6fca:A 209 211 0.2310 0.3206 0.3175 6.57e-17 6fct:A, 6fcw:A, 6fcy:A, 6fd9:A, 6ftt:E, 6ftt:H, 6ftt:G, 6ftt:F, 6fu2:C, 6fu2:D, 6fu7:C, 6fu7:D, 6fua:C, 6fua:D, 6r02:E, 6r02:F, 6r02:G, 6r02:H, 7z6r:C, 7z6r:D, 7z8u:A
9 1z7n:F 205 190 0.2000 0.2829 0.3053 8.85e-17 1z7m:G, 1z7m:E, 1z7m:H, 1z7n:E, 1z7n:G, 1z7n:H
10 1usy:G 203 200 0.2103 0.3005 0.3050 1.51e-16 1usy:F, 1usy:E, 1usy:H
11 6wzg:R 379 58 0.0655 0.0501 0.3276 0.044 7d3s:R, 6wi9:R
12 5zku:F 443 45 0.0483 0.0316 0.3111 0.95 5zku:A, 5zku:B, 5zku:C, 5zku:D, 5zku:E, 5zkw:A, 5zkw:B, 5zkw:C, 5zkw:E, 5zkw:F, 5zl4:A, 5zla:A, 5zla:D, 5zla:B, 5zla:C, 5zla:F, 5zla:E
13 4oua:B 557 141 0.1241 0.0646 0.2553 2.1 5m6b:B, 5m6b:A, 5m6b:D, 4oua:A
14 6hxi:B 616 41 0.0517 0.0244 0.3659 2.8 6hxi:D, 6znw:B
15 3cg3:A 315 61 0.0621 0.0571 0.2951 2.9
16 7r5v:N 297 79 0.0759 0.0741 0.2785 3.0 7yyh:N
17 1uoc:A 263 59 0.0621 0.0684 0.3051 3.2 1uoc:B
18 5c56:A 528 118 0.0897 0.0492 0.2203 3.6 5c6d:A, 5c6d:B, 5gg4:A, 5gg4:B, 5gg4:C, 5gg4:D, 6p5l:A, 4wph:B, 4wph:A, 4wpi:B, 4wpi:A, 7xpy:A, 4z96:A, 4z97:A
19 8qqk:B 263 35 0.0414 0.0456 0.3429 6.6 1cyx:A, 1fft:B, 8go3:B, 7n9z:G, 6wti:B, 7xmc:B, 7xmd:B
20 7fcm:B 269 40 0.0483 0.0520 0.3500 7.0 7f44:A, 7fcm:A
21 7fc8:A 243 40 0.0483 0.0576 0.3500 7.5
22 4b98:A 441 20 0.0310 0.0204 0.4500 10.0 4b98:B, 4b98:C, 4b98:D, 4b9b:A, 4b9b:B, 4b9b:C, 4b9b:D, 4b9b:E, 4b9b:F, 4b9b:G, 4b9b:H, 4bq0:A, 4bq0:B, 4bq0:C, 4bq0:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218