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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NTINIAKNDFSDIELAAIPFNTLADHYGERLAREQLALEHESYEMGEARFRKMFERQLKAGEVADNAAAKPLITTLLPKM
IARINDWFEEVKAKRAYITIKTTLACLTSADNTTVQAVASAIGRAIEDEARFGRIRDLEAKHFKKNVEEQLNKRVGHVYK
KAFMSWHKEDSIHVGVRCIEMLIESETIELAPEYAEAIATRAGALAGISPMFQPCVVPPKPWTGITGGGYWANGRRPLAL
VRTHSKKALMRYEDVYMPEVYKAINIAQNTAWKINKKVLAVANVITKWKHCPVEDIPEALTAWKRAAAAVYRKDKARKSR
RISLEFMLEQANKFANHKAIWFPYNMDWRGRVYAVSMFNPQGNDMTKGLLTLAKGKPIGKEGYYWLKIHGANCAGVDKVP
FPERIKFIEENHENIMACAKSPLENTWWAEQDSPFCFLAFCFEYAGVQHHGLSYNCSLPLAFDGSCSGIQHFSAMLRDEV
GGRAVNLLPSETVQDIYGIVAKKVNEILQADAINGTDNEVKLGTKALAGQWLAYGVTRSVTKRSVMTLAYGSKEFGFRQQ
VLEDTIQPAIDSGKGLMFTQPNQAAGYMAKLIWESVSVTVVAAVEAMNWLKSAAKLLAAEVKDKKTGEILRKRCAVHWVT
PDGFPVWQEYKKPIQTRLDSEIDAHKQESGIAPNFVHSQDGSHLRKTVVWAHEKYGIESFALIHDSFGTIPADAANLFKA
VRETMVDTYESCDVLADFYDQFADQLHESQLDKMPALPAKGNLNLRDILESDFAF

The query sequence (length=775) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8dh3:M 775 775 1.0000 1.0000 1.0000 0.0 8dh0:N
2 8dh3:E 825 824 0.9923 0.9321 0.9333 0.0 8dh4:M, 8dh5:E
3 8dh4:I 821 823 0.9897 0.9342 0.9320 0.0 8dh0:J
4 1msw:D 863 862 0.9987 0.8969 0.8979 0.0 1cez:A, 8dh1:B, 8dh2:B, 8dh3:B, 8dh4:B, 8dh5:B, 3e2e:A, 3e3j:C, 3e3j:B, 1h38:A, 1h38:B, 1h38:C, 1h38:D, 2pi4:A, 2pi5:A, 1qln:A, 1s0v:A, 1s0v:B, 1s0v:C, 1s0v:D
5 8dh2:E 841 846 0.9871 0.9096 0.9043 0.0 8dh0:B, 8dh1:E, 8dh1:I, 8dh2:I, 8dh3:I, 8dh4:E, 8dh5:I, 1s76:D, 1s77:D
6 8dh0:F 796 807 0.9716 0.9460 0.9331 0.0
7 8dh5:M 740 783 0.9381 0.9824 0.9285 0.0
8 8dh2:L 741 786 0.9329 0.9757 0.9198 0.0
9 8dh1:L 702 775 0.8994 0.9929 0.8994 0.0
10 8c5s:A 924 708 0.2632 0.2208 0.2881 4.55e-72 8ap1:A, 8att:A, 8atv:A, 8atw:A, 8c5u:A, 8q63:A, 6ymw:A
11 6ymv:A 887 706 0.2555 0.2232 0.2805 1.20e-68
12 9bdc:E 990 623 0.2387 0.1869 0.2970 4.03e-67 9bdd:E, 4boc:A, 5ola:E, 5ola:F, 8u8u:E, 8u8v:E
13 3spa:A 941 604 0.2323 0.1913 0.2980 7.97e-67 7a8p:A
14 6erp:A 1011 622 0.2335 0.1790 0.2910 4.64e-66 6erp:B, 6erq:A, 6erq:B
15 6dt7:B 404 394 0.1161 0.2228 0.2284 6.57e-06 6dt8:B, 6dta:B
16 8aaf:e 1527 73 0.0245 0.0124 0.2603 4.3 8agt:e, 8agu:e, 8agv:e, 8agw:e, 8agx:e, 8agz:e
17 5cuy:D 396 175 0.0465 0.0909 0.2057 8.6 5c5v:A, 5c5v:B, 5cuy:A, 5cuy:B, 5cuy:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218