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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NSQVTVAVRVRPFSKREKTEKASQVVFTNGEEITVEHPDMKQVYSFIYDVSFWSFDECHPGYASQTTVYETLAAPLLDRA
FEGYNTCLFAYGQTGSGKSYTMMGLNEEPGIIPRFCEDLFAQIAKKQTSEVSYHLEMSFFEVYNEKIHDLLVCKGENGQR
KQPLRAREHPVSGPYVEGLSMNVVSSYSDIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEVVEGEEHDHRI
TSRINLVDLAGSERCSTAHSSGQRLKEGVSINKSLLTLGKVISALSEQANGKRVFIPYRESTLTWLLKESLGGNSKTAMI
ATVSPAASNIEETLSTLRYATQARL

The query sequence (length=345) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6wwk:K 368 345 1.0000 0.9375 1.0000 0.0 7lvq:K, 7lvr:K, 6wwf:K, 6wwg:K, 6wwg:N, 6wwh:K, 6wwh:N, 6wwj:K, 6wwk:N, 6wwl:K, 6wwl:N, 6wwm:K, 6wwn:K, 6wwo:K, 6wwq:K, 6wwr:K, 6wws:K, 6wwu:K, 6wwv:K
2 4ozq:B 687 344 0.9217 0.4629 0.9244 0.0 4ozq:A
3 8uto:N 389 356 0.5159 0.4576 0.5000 3.69e-114 2hxh:C, 1i5s:A, 8utn:K, 8utn:N, 8uto:K, 8utp:K, 8utp:N, 8utq:K, 8utr:K, 8utt:K, 8utt:N, 8utu:K, 8utv:K, 8uty:K, 8uty:N, 4uxp:C, 1vfz:A
4 7eo9:A 351 348 0.4957 0.4872 0.4914 2.09e-106 7eob:A, 2hxf:C, 1i6i:A, 1ia0:K, 1vfv:A, 1vfw:A, 1vfx:A, 2zfi:A, 2zfj:A, 2zfk:A, 2zfl:A, 2zfm:A
5 6a20:A 395 347 0.4957 0.4329 0.4928 6.97e-103 6a1z:A, 7d8v:A, 3gbj:B, 5zbr:B, 5zbr:A, 5zbr:C, 5zbs:B, 5zbs:A
6 5zbs:C 323 344 0.4754 0.5077 0.4767 2.06e-99 3gbj:A, 3gbj:C
7 2owm:A 328 304 0.4464 0.4695 0.5066 1.60e-94 2owm:B, 2owm:C, 2owm:D
8 7wrg:A 812 353 0.4696 0.1995 0.4589 1.83e-88
9 7wrg:B 783 352 0.4609 0.2031 0.4517 1.71e-83
10 3zfd:A 340 349 0.4377 0.4441 0.4327 1.80e-82 3zfc:A
11 7a5e:A 338 347 0.4261 0.4349 0.4236 1.80e-76 7a5e:B
12 3b6u:B 343 354 0.4087 0.4111 0.3983 1.05e-72 3b6u:A
13 7lxr:B 344 355 0.4203 0.4215 0.4085 2.19e-71 7lxr:A, 6vpo:C, 2wbe:C
14 6zpi:C 332 298 0.3768 0.3916 0.4362 9.88e-71 4bn2:A, 4bn2:B, 6zph:B
15 1t5c:A 322 341 0.3913 0.4193 0.3959 1.38e-70 8hfh:A, 6m4i:A, 6m4i:B, 1t5c:B
16 1goj:A 354 345 0.3942 0.3842 0.3942 2.47e-69
17 4aqv:C 361 359 0.4029 0.3850 0.3872 2.11e-68 4a28:A, 4a50:A, 4a5y:A, 4a5y:C, 4as7:A, 4b7b:A, 4bbg:A, 4bxn:A, 4bxn:B, 3cjo:A, 3cjo:B, 4ck6:C, 4ck7:C, 2fky:A, 2fky:B, 2fl2:A, 2fl2:B, 2fl6:A, 2fl6:B, 2fme:B, 2g1q:A, 2g1q:B, 6g6z:A, 6hkx:B, 3hqd:A, 3hqd:B, 2ieh:A, 2ieh:B, 1ii6:A, 1ii6:B, 3k3b:A, 3k3b:B, 3k5e:A, 3ken:A, 3l9h:A, 3l9h:B, 2pg2:A, 2pg2:B, 1q0b:A, 1q0b:B, 2q2y:A, 2q2y:B, 2q2z:A, 2q2z:B, 6ta4:K, 6tle:A, 6tle:B, 6trl:B, 2uyi:A, 2uyi:B, 2uym:A, 2uym:B, 2wog:A, 2wog:B, 2wog:C, 2x2r:A, 2x2r:C, 2x7c:A, 2x7c:B, 2x7d:A, 2x7d:B, 2x7e:A, 2x7e:B, 1x88:A, 1x88:B, 2xae:C, 1yrs:A, 1yrs:B, 4zca:A, 4zhi:A, 4zhi:B, 5zo7:A, 5zo7:B
18 5ocu:K 333 344 0.4000 0.4144 0.4012 4.93e-68 5ogc:K
19 6ta3:K 334 348 0.3855 0.3982 0.3822 7.64e-68 4a1z:A, 4a1z:B, 4a28:B, 4a51:A, 4a51:B, 4a51:C, 4a51:D, 4ap0:A, 2fme:A, 6g6y:A, 2gm1:A, 2gm1:E, 6hkx:A, 6hky:A, 6hky:B, 3k5e:B, 6tiw:K, 2x2r:B, 2xae:A, 2xae:B, 6y1i:A, 6y1i:B, 6y1i:C, 8yhh:A, 3zcw:A, 4zca:B
20 7rs5:K 346 354 0.3855 0.3844 0.3757 2.57e-67 7rs5:a, 7rs5:b, 7rs5:c, 7rs5:d, 7rs5:e, 7rs5:f, 7rs5:g, 7rs5:h, 7rs6:K, 7rs6:a, 7rs6:b, 7rs6:c, 7rs6:d, 7rs6:e, 7rs6:f, 7rs6:g, 7rs6:h
21 5m5i:C 369 365 0.3884 0.3631 0.3671 3.37e-66 5m5l:C, 5m5m:C, 5m5n:C, 5m5o:C
22 6s8m:K 344 356 0.3855 0.3866 0.3736 8.71e-66
23 7rx0:C 328 349 0.4029 0.4238 0.3983 1.09e-65 6mlq:C, 6mlr:C
24 7z2b:K 308 344 0.3594 0.4026 0.3605 5.67e-64
25 7tr1:K 346 353 0.3681 0.3671 0.3598 8.20e-64 7lff:A, 7lff:B
26 3cob:A 355 346 0.3739 0.3634 0.3728 1.21e-63 3cob:C, 1sdm:A
27 5zo8:A 331 357 0.3913 0.4079 0.3782 4.47e-63 4a51:G, 4a51:E, 4a51:F, 4a5y:B, 4ap0:D, 4ap0:B, 2gm1:B, 2gm1:D, 6hky:C, 6trl:A, 8yhh:B, 5zo8:B, 5zo9:A, 5zo9:B
28 4uy0:C 333 295 0.3333 0.3453 0.3898 7.70e-62
29 7nba:K 331 345 0.3536 0.3686 0.3536 1.27e-61
30 2vvg:B 309 344 0.3710 0.4142 0.3721 1.34e-60 2vvg:A
31 5mm7:K 397 379 0.4029 0.3501 0.3668 1.39e-60 5mm4:K
32 5wde:A 320 343 0.3768 0.4062 0.3790 4.04e-60
33 7a3z:A 307 350 0.3971 0.4463 0.3914 1.25e-59
34 2y65:C 343 344 0.3681 0.3703 0.3692 3.95e-59 2y5w:A, 2y5w:B, 2y65:D, 2y65:B, 2y65:A
35 5hnw:K 329 341 0.3507 0.3678 0.3548 8.87e-59 5hle:A, 5hny:K, 3x2t:B
36 3h4s:A 359 347 0.3565 0.3426 0.3545 1.29e-58 4frz:A, 4frz:B
37 7tr3:K 418 296 0.3333 0.2751 0.3885 1.45e-58 7tqx:K, 7tqy:K, 7tr0:K
38 4bn2:C 311 295 0.3478 0.3859 0.4068 2.10e-58
39 4ap0:C 311 355 0.3710 0.4116 0.3606 3.41e-58
40 7x4n:E 332 353 0.3594 0.3735 0.3513 4.80e-58
41 3lre:B 300 345 0.3710 0.4267 0.3710 1.47e-56 3lre:A, 7rsi:C
42 1mkj:A 336 346 0.3391 0.3482 0.3382 3.31e-56 4atx:C, 1bg2:A, 4hna:K, 8ixa:Y, 8ixa:S, 8ixa:T, 8ixa:U, 8ixa:V, 8ixa:W, 8ixa:X, 8ixa:Z, 8ixa:a, 8ixb:l, 8ixb:g, 8ixb:k, 8ixb:m, 8ixd:Y, 8ixd:S, 8ixd:T, 8ixd:U, 8ixd:V, 8ixd:W, 8ixd:X, 8ixd:Z, 8ixd:a, 8ixe:l, 8ixe:h, 8ixe:p, 8ixe:q, 8ixf:Y, 8ixf:S, 8ixf:T, 8ixf:U, 8ixf:V, 8ixf:W, 8ixf:X, 8ixf:Z, 8ixf:a, 8ixg:l, 8ixg:h, 8ixg:p, 8ixg:q, 3j8y:K, 2p4n:K
43 3b6v:A 306 353 0.3507 0.3954 0.3428 6.55e-56 3b6v:B
44 7n61:0X 420 353 0.3536 0.2905 0.3456 2.13e-55 7n61:0Y, 7n61:0Z, 7n61:1A
45 2xt3:A 300 343 0.3768 0.4333 0.3790 7.48e-55 4a14:A
46 3x2t:A 311 344 0.3449 0.3826 0.3459 1.33e-53 2kin:A, 3kin:A, 3kin:C
47 1cz7:D 365 338 0.3536 0.3342 0.3609 1.70e-53 1cz7:A, 1cz7:B, 1cz7:C, 3l1c:A, 1n6m:A, 2ncd:A, 3u06:A, 5w3d:A
48 5mio:C 477 345 0.3507 0.2537 0.3507 1.74e-52 1v8j:A, 5xjb:A
49 3nwn:A 308 286 0.3188 0.3571 0.3846 3.05e-52
50 6b0l:K 368 353 0.3478 0.3261 0.3399 8.28e-52 6b0c:K
51 5gsz:A 306 359 0.3739 0.4216 0.3593 2.29e-51
52 3t0q:A 304 344 0.3478 0.3947 0.3488 3.18e-51
53 3cnz:A 333 344 0.3391 0.3514 0.3401 9.84e-51 3cnz:B
54 3wpn:A 309 349 0.3594 0.4013 0.3553 1.96e-50
55 6bbn:E 378 346 0.3449 0.3148 0.3439 6.81e-50 2gry:A
56 5nd4:C 337 352 0.3188 0.3264 0.3125 1.51e-48
57 4etp:A 379 291 0.3130 0.2850 0.3711 7.52e-47 1f9t:A, 1f9u:A, 1f9v:A, 3kar:A
58 4gkr:B 307 291 0.3130 0.3518 0.3711 2.73e-46 4gkr:A
59 5xja:A 337 346 0.3391 0.3472 0.3382 1.87e-45 3edl:D, 2heh:A, 4ubf:B, 4ubf:C, 4ubf:D, 1v8k:A, 5xja:B, 5xjb:B, 4y05:A
60 3u06:B 344 338 0.3304 0.3314 0.3373 7.01e-44 3l1c:B, 1n6m:B
61 5wdh:A 296 346 0.3536 0.4122 0.3526 1.18e-43
62 3dcb:A 299 350 0.3304 0.3813 0.3257 2.09e-43 3dc4:A, 3dco:N, 3pxn:A
63 5nd7:C 300 345 0.2957 0.3400 0.2957 2.22e-40
64 4ubf:A 309 344 0.3275 0.3657 0.3285 5.27e-40
65 1f9w:A 300 341 0.3362 0.3867 0.3402 1.79e-38 1f9w:B
66 4h1g:A 670 289 0.3101 0.1597 0.3702 3.40e-38
67 6nje:A 297 295 0.2667 0.3098 0.3119 9.14e-37
68 5w3d:B 313 338 0.3304 0.3642 0.3373 8.01e-35
69 5nd2:C 280 343 0.2667 0.3286 0.2682 4.71e-30
70 8bjs:A 343 387 0.2725 0.2741 0.2429 9.20e-25
71 6xds:A 485 74 0.0754 0.0536 0.3514 1.6 6b8o:B, 6b8o:E, 6b8o:C, 6b8o:F, 6b8o:A, 6b8o:D
72 2gtl:M 217 101 0.0812 0.1290 0.2772 2.0
73 7k3z:A 564 108 0.0812 0.0496 0.2593 2.0 7k3z:B, 7k3z:C, 7k3z:D, 7k3z:E, 7k3z:F, 7k3z:G
74 4ozt:E 238 39 0.0348 0.0504 0.3077 3.3
75 6z1p:Bw 662 25 0.0348 0.0181 0.4800 3.7
76 3qwu:A 366 60 0.0406 0.0383 0.2333 7.3 3qwu:B
77 5y2g:A 581 76 0.0696 0.0413 0.3158 8.1
78 5jst:B 432 76 0.0696 0.0556 0.3158 9.3 5jst:A
79 7kd4:A 431 76 0.0696 0.0557 0.3158 9.4 7kd4:B, 7kd5:A
80 8xxn:CD 347 54 0.0580 0.0576 0.3704 9.5 9bkd:U, 9bln:p, 8xxl:CD, 8xxm:CD
81 4ikm:A 463 76 0.0696 0.0518 0.3158 9.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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