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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NSIIGEKYRWPHTIPYVLEDSLEMNAKGVILNAFERYRLKTCIDFKPWAGETNYISVFKGSGCWSSVGNRRVGKQELSIG
ANCDRIATVQHEFLHALGFWHEQSRSDRDDYVRIMWDRILSGREHNFNTYSDDISDSLNVPYDYTSVMHYSKTAFQNGTE
PTIVTRISDFEDVIGQRMDFSDSDLLKLNQLYNCSSSLSFMDSCSFELENVCGMIQSSGDNADWQRVSQVPRGPESDHSN
MGQCQGSGFFMHFDSSSVNVGATAVLESRTLYPKRGFQCLQFYLYNSGSESDQLNIYIREYSADNVDGNLTLVEEIKEIP
TGSWQLYHVTLKVTKKFRVVFEGRKGSGASLGGLSIDDINLSETRCPHHIWHIRNFTQFIGSPNGTLYSPPFYSSKGYAF
QIYLNLAHVTNAGIYFHLISGANDDQLQWPCPWQQATMTLLDQNPDIRQRMSNQRSITTDPFMTTDNGNYFWDRPSKVGT
VALFSNGTQFRRGGGYGTSAFITHERLKSRDFIKGDDVYILLTVEDISHLNST

The query sequence (length=533) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4gwm:A 561 533 0.9775 0.9287 0.9775 0.0 7aq1:A, 7aq1:B, 7auw:A, 7auw:C, 4gwm:B, 4gwn:A
2 7uac:H 546 539 0.4690 0.4579 0.4638 3.14e-165 7uab:E, 7uab:H, 7uae:A, 7uaf:B, 7uaf:A, 7uaf:C, 7uaf:D, 7uai:E, 7uai:B, 7uai:C, 7uai:D
3 7uab:A 481 527 0.3921 0.4345 0.3966 5.07e-113 7uab:D
4 3lqb:A 198 182 0.1482 0.3990 0.4341 1.09e-41
5 8a28:A 382 352 0.2120 0.2958 0.3210 2.41e-41 8a28:B
6 3vtg:A 200 183 0.1445 0.3850 0.4208 9.73e-39
7 6bsl:A 201 192 0.1295 0.3433 0.3594 2.59e-34 6bsl:B, 6bsm:A, 6btn:A, 6btn:B, 6bto:A, 6bto:B, 6btp:A, 6btp:B, 6btq:A, 6btq:B, 3edg:A, 3edh:A
8 3edi:A 195 191 0.1295 0.3538 0.3613 7.39e-28
9 3lq0:A 235 204 0.1370 0.3106 0.3578 6.79e-26 1ast:A, 6ht9:A, 6ht9:C, 1iaa:A, 1iab:A, 1iac:A, 1iae:A, 1qji:A, 1qjj:A, 6saz:A, 6saz:C
10 5yc1:F 164 167 0.0882 0.2866 0.2814 2.95e-10 5yc1:D, 5yc1:A
11 5l73:A 174 131 0.0732 0.2241 0.2977 1.06e-07 5l73:B
12 1ca9:A 191 85 0.0563 0.1571 0.3529 5.28e-06 1ca9:E, 1ca9:B, 1czy:A, 1czy:C, 1czz:A, 1czz:B, 1d00:A, 1d00:B, 1d00:F, 1d00:C, 1d00:D, 1d00:E, 1d00:G, 1d00:H, 1d01:D, 1d01:E, 1d01:F, 1d0a:A, 1d0a:B, 1d0a:C, 1d0a:D, 1d0a:E, 1d0a:F, 1d0j:A, 1d0j:C, 1d0j:D, 1d0j:E, 1d0j:F, 1qsc:A, 1qsc:B, 1qsc:C, 8t5q:A, 8t5q:B, 8t5q:D
13 6myd:A 155 162 0.0844 0.2903 0.2778 1.04e-05 6myd:C
14 1fll:A 205 166 0.0807 0.2098 0.2590 3.80e-05 1fll:B, 4ghu:A, 2gkw:A, 1kzz:A, 1l0a:A, 1rf3:A, 8t5p:A, 8t5p:B, 8t5p:D, 1zms:A
15 4z8m:B 158 177 0.0844 0.2848 0.2542 2.03e-04 6a33:A, 1lb5:A, 1lb6:A, 4z8m:A, 5zuj:A
16 5gwd:A 239 127 0.0657 0.1464 0.2756 2.6 5czw:A, 5gwd:B, 5zjk:A, 5zjk:B, 5zjk:C, 5zjk:D, 5zjk:E, 5zjk:F, 5zjk:G, 5zjk:H, 5zjk:I, 5zjk:J, 5zjk:K, 5zjk:L, 5zjk:M, 5zjk:N, 5zjk:O, 5zjk:P, 5zjk:Q, 5zjk:R
17 4ccl:B 372 67 0.0413 0.0591 0.3284 4.1 4ccl:A, 4lit:A, 4liv:A, 4nub:A
18 4blt:A 305 46 0.0263 0.0459 0.3043 4.2 4blr:A, 4blr:B, 4blr:C, 4bls:A, 4bls:B, 4bls:C, 4blt:B, 4blt:C, 2vhc:A, 2vhc:C, 2vhc:B, 2vhj:A, 2vhj:B, 2vhj:C, 2vhq:A, 2vhq:B, 2vhq:C, 2vht:A, 2vht:B, 2vht:C, 2vhu:A, 2vhu:B, 2vhu:C, 1w44:A, 1w44:B, 1w44:C, 1w46:A, 1w46:B, 1w46:C, 1w47:A, 1w47:B, 1w47:C, 1w48:A, 1w48:B, 1w48:C, 1w49:A, 1w49:B, 1w49:C, 1w4a:A, 1w4a:B, 1w4a:C, 1w4b:A, 1w4b:B, 1w4b:C
19 7ssj:A 219 78 0.0432 0.1050 0.2949 7.6 3ehf:A, 3ehf:D, 3ehg:A, 3ehh:A, 3ehh:B, 3ehj:A, 3ehj:B, 3gie:A, 3gie:B, 3gif:A, 3gig:A, 3gig:B, 5iuj:A, 5iuj:B, 5iuj:D, 5iuj:E, 5iuk:A, 5iuk:B, 5iuk:D, 5iuk:E, 5iul:A, 5iul:B, 5iul:D, 5iul:E, 5ium:A, 5ium:B, 7ssi:A, 7ssi:B, 7ssi:D, 7ssi:E, 7ssj:C, 7ssj:D
20 8s1u:H 518 37 0.0281 0.0290 0.4054 9.1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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