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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NRHFIDADPYPWPYNGALRPDNTALIIIDMQTDFCGKGGYVDHMGYDLSLVQAPIEPIKRVLAAMRAKGYHIIHTREGHR
PDLADLPANKRWRSQRIGAGIGDPGPCGRILTRGEPGWDIIPELYPIEGETIIDKPGKGSFCATDLELVLNQKRIENIIL
TGITTDVSVSTTMREANDRGYECLLLEDCCGATDYGNHLAAIKMVKMQGGVFGSVSNSAALVEALP

The query sequence (length=226) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6azq:G 226 226 1.0000 1.0000 1.0000 1.84e-170 6azq:H, 6azq:A, 6azq:B, 6azq:C, 6azq:D, 6azq:E, 6azs:B, 6azs:D
2 6xjm:D 230 221 0.6593 0.6478 0.6742 1.19e-108 6xjm:A, 6xjm:B, 6xjm:C
3 6xje:B 220 209 0.4469 0.4591 0.4833 8.55e-68 6xj4:B, 6xje:A, 6xje:C, 6xje:D
4 8bkd:F 224 209 0.2655 0.2679 0.2871 2.94e-22 8bkd:C, 8bkd:D, 8bkd:G, 8bkd:H, 8bkd:J, 8bkd:K, 8bkd:L
5 8cib:D 196 207 0.2743 0.3163 0.2995 1.88e-13 8cib:F
6 3eef:A 173 169 0.1770 0.2312 0.2367 5.46e-13 3eef:B
7 3s2s:A 182 191 0.2035 0.2527 0.2408 4.79e-09 3s2s:B, 3s2s:C, 3s2s:D
8 5hwg:A 175 81 0.1150 0.1486 0.3210 6.51e-09 5hwh:A
9 1im5:A 179 190 0.2124 0.2682 0.2526 1.78e-07
10 3o93:A 190 184 0.2124 0.2526 0.2609 2.38e-07 3o90:A, 3o90:B, 3o90:C, 3o90:D, 3o91:A, 3o91:B, 3o91:C, 3o91:D, 3o92:A, 3o92:B, 3o92:C, 3o92:D, 3o93:B, 3o93:C, 3o93:D, 3o94:A, 3o94:B, 3o94:C, 3o94:D
11 1nba:A 253 139 0.1681 0.1502 0.2734 3.43e-07 1nba:B, 1nba:C, 1nba:D
12 2fq1:A 279 196 0.2080 0.1685 0.2398 6.63e-05
13 2wta:A 212 212 0.2168 0.2311 0.2311 8.12e-05 2wt9:A, 2wt9:B
14 6a8l:A 183 191 0.1814 0.2240 0.2147 1.21e-04 6a8l:B, 5zn8:A, 5zn8:B
15 3pl1:A 185 192 0.2080 0.2541 0.2448 0.011
16 6kua:A 163 51 0.0752 0.1043 0.3333 0.079
17 3p2y:A 345 136 0.1770 0.1159 0.2941 1.5
18 1y9i:A 159 27 0.0487 0.0692 0.4074 2.3 1y9i:B, 1y9i:C, 1y9i:D
19 2h0r:A 216 191 0.1858 0.1944 0.2199 2.5 2h0r:B, 2h0r:C, 2h0r:D, 2h0r:E, 2h0r:F, 2h0r:G, 3v8e:A, 3v8e:B, 3v8e:C, 3v8e:D, 3v8e:E, 3v8e:F, 3v8e:G
20 7kd7:A 204 58 0.0619 0.0686 0.2414 2.8 7kd7:D, 7kpu:D, 7kpu:A, 4u9v:B, 4u9w:B, 4u9w:A, 4u9w:C, 4u9w:D
21 4wgf:A 202 78 0.0796 0.0891 0.2308 4.2 4wgf:E, 4wgf:B, 4wgf:H, 4wgf:C, 4wgf:G, 4wgf:D, 4wgf:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218