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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSEG
LQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCH
AEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEARGQLRTKIESGQ
GTIPVRSLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGI
SNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLA
AKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLT

The query sequence (length=436) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8e0f:B 454 454 1.0000 0.9604 0.9604 0.0 6d06:A, 6d06:D, 8e0f:A, 8e4x:A, 8e4x:B, 5ed1:A, 5ed1:D, 5ed2:A, 5ed2:D, 5hp2:A, 5hp2:D, 5hp3:A, 5hp3:D, 7kfn:A, 7kfn:D, 2l2k:B, 6vff:A, 6vff:B, 1zy7:A, 1zy7:B
2 2l3j:A 236 67 0.1491 0.2754 0.9701 1.46e-37 2l3c:A
3 2l3j:A 236 59 0.0803 0.1483 0.5932 2.10e-13 2l3c:A
4 5dv7:C 137 46 0.0688 0.2190 0.6522 4.00e-12
5 5dv7:C 137 59 0.0688 0.2190 0.5085 4.90e-11
6 1ekz:A 76 53 0.0413 0.2368 0.3396 5.25e-04
7 6sdw:A 177 64 0.0550 0.1356 0.3750 0.001 6htu:A, 6htu:B, 6htu:C, 6sdy:A
8 6sdw:A 177 54 0.0482 0.1186 0.3889 0.015 6htu:A, 6htu:B, 6htu:C, 6sdy:A
9 7zpk:C 233 65 0.0665 0.1245 0.4462 0.005 3adl:A, 5n8l:A, 5n8m:A
10 4kzk:A 301 82 0.0596 0.0864 0.3171 0.22
11 1di2:A 69 46 0.0367 0.2319 0.3478 0.36
12 9asp:C 92 48 0.0413 0.1957 0.3750 0.46
13 8pcx:A 232 49 0.0367 0.0690 0.3265 4.2 8bjo:A, 8bxz:A, 8p6o:A, 8pc3:A, 8pc8:A, 8pdt:A, 8ped:A, 8qli:A, 8r43:A, 8rbn:A
14 4rdr:A 706 30 0.0298 0.0184 0.4333 4.3
15 9asp:B 250 61 0.0436 0.0760 0.3115 5.3 9asm:B, 9asn:B, 9asq:B
16 8dfv:K 253 78 0.0482 0.0830 0.2692 6.1 8dg5:K
17 8dfv:K 253 72 0.0573 0.0988 0.3472 7.9 8dg5:K
18 6v5b:C 217 50 0.0390 0.0783 0.3400 8.1 6v5b:B, 6v5c:C, 6v5c:B
19 1yyk:A 221 53 0.0367 0.0724 0.3019 8.5 2ez6:A, 2ez6:B, 1jfz:A, 1jfz:B, 1jfz:C, 1jfz:D, 4m2z:A, 4m2z:B, 4m30:A, 4m30:B, 2nue:A, 2nuf:A, 2nuf:B, 2nug:A, 2nug:B, 1rc5:A, 1rc5:B, 1rc5:C, 1rc5:D, 1rc7:A, 1yyo:A, 1yyw:A, 1yyw:C, 1yz9:A
20 4rdt:A 635 34 0.0367 0.0252 0.4706 9.1 4rdt:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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