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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NPSPDHYAVWGKAIMAENNRRVGPEHMFRTAIRAQQQLQGLADKWTPDAKVYCCGSMVTYGQMERGSDLDLACMFDDPYP
SHEVQAKRTDKLRTVIKRYVPHYLRNNLLGLTEARTPVVKLRFANDEKVARARYTPLSEEEDRKARTALLDVRNQCVGDN
DVEYIAEKMGRDNVEGIRVDRTTYGCRIAIQCTSKEQMIEAIGFFPDGKIMTRGMREDYTRDVLDVRFVPEMFMYRWDIS
FVGYGVKNSYLIRHYLHNGPVAARHTAMAVKAWGKATNVGAGSGAMLTSYAVTVMFIYYLLVTRQVLWVDPWSLPHPAHL
PRYPDFSPLYDCDPTELGRLLHGFFIFYAHHFDYEREVVSLNRNRRSYRSDIGWNFPQNKKGTFSYNFCIEDPYEDVGTG
GLNLVRHLHPAKFQLVKQEFLRAAQCMERFLPTNAPEKSILGVK

The query sequence (length=444) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2b51:A 444 444 1.0000 1.0000 1.0000 0.0 2b56:A
2 5hzd:A 476 434 0.2995 0.2794 0.3065 1.11e-42 5i49:A, 5ido:A
3 2nom:B 255 190 0.1396 0.2431 0.3263 8.87e-21
4 2q0e:A 331 191 0.1441 0.1934 0.3351 2.06e-20 2ikf:A, 5kal:A, 5kal:B, 2nom:A, 2q0c:A, 2q0d:A, 2q0f:A, 2q0f:B, 2q0g:A, 2q0g:B
5 2q0e:A 331 28 0.0270 0.0363 0.4286 2.2 2ikf:A, 5kal:A, 5kal:B, 2nom:A, 2q0c:A, 2q0d:A, 2q0f:A, 2q0f:B, 2q0g:A, 2q0g:B
6 4nkt:B 308 195 0.1194 0.1721 0.2718 1.37e-08
7 4e80:C 330 214 0.1284 0.1727 0.2664 2.90e-08 4e80:A, 4e80:B, 4e80:D, 4ep7:A, 4ep7:B, 4fh5:A, 4fhp:A, 4fhv:A, 4fhw:A, 4fhx:A, 4fhy:A, 4nkt:A, 4nku:A, 4nku:B
8 6ywo:A 354 196 0.1171 0.1469 0.2653 1.95e-07 6ywn:A, 6ywo:B, 6ywo:C, 6ywo:D
9 7xs4:A 329 207 0.1149 0.1550 0.2464 2.31e-07 6l8k:A
10 5jnb:B 324 168 0.0968 0.1327 0.2560 3.41e-06 5jnb:C, 5jnb:D
11 8opt:A 783 182 0.0946 0.0536 0.2308 4.17e-06 8ops:A, 5w0m:B, 5w0n:C, 5w0o:A, 5w0o:B
12 5w0n:A 379 188 0.0968 0.1135 0.2287 9.89e-06 5w0m:A, 5w0m:C, 5w0n:B
13 8opp:A 670 176 0.0923 0.0612 0.2330 6.15e-05
14 5w0b:A 334 127 0.0698 0.0928 0.2441 3.83e-04
15 5z4a:A 351 137 0.0698 0.0883 0.2263 0.35 6i0s:A, 6i0t:A, 6i0u:A, 6i0v:A, 5z4d:A, 5z4j:A, 5z4m:A
16 8idf:A 459 51 0.0428 0.0414 0.3725 0.43
17 5wu3:B 485 31 0.0270 0.0247 0.3871 0.67 5wu2:A, 5wu2:B, 5wu3:A, 5wu4:A, 5wu4:B
18 3hj1:B 387 114 0.0766 0.0879 0.2982 2.3 3hiy:A, 3hiy:B, 3hj1:A
19 7znn:B 559 79 0.0518 0.0411 0.2911 3.7 7zn7:B
20 1no5:B 102 32 0.0315 0.1373 0.4375 7.5 1no5:A
21 8iff:A 868 163 0.0878 0.0449 0.2393 8.9 8f5z:B, 8f5z:A, 8iff:B, 8isj:A, 8isj:B
22 7ap5:AAA 164 34 0.0270 0.0732 0.3529 9.0 7ap5:CCC, 7ap5:EEE, 7ap5:GGG, 7ap5:III, 7ap5:KKK, 7ap5:MMM, 7ap5:OOO, 5aqd:A, 5aqd:B, 5aqd:C, 5aqd:D, 5aqd:E, 5aqd:F, 5aqd:G, 5aqd:H, 5aqd:I, 5aqd:J, 5aqd:K, 5aqd:L, 7f86:A, 7f86:W, 7f86:D, 7f86:B, 7f86:F, 7f86:H, 7f86:J, 7f86:L, 7f86:O, 7f86:Q, 7f86:U, 7f86:Y, 5fvb:A, 5fvb:B, 5fvb:C, 5fvb:D, 5fvb:E, 5fvb:F, 5fvb:G, 5fvb:H, 5fvb:I, 5fvb:J, 5fvb:K, 5fvb:L, 5nb3:A, 5nb3:B, 5nb3:C, 5nb3:D, 5nb3:E, 5nb3:F, 5nb3:G, 5nb3:H, 5nb3:I, 5nb3:J, 5nb3:K, 5nb3:L, 5nb4:A, 5nb4:B, 5nb4:C, 5nb4:D, 5nb4:E, 5nb4:F, 5nb4:G, 5nb4:H, 5nb4:I, 5nb4:J, 5nb4:K, 5nb4:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218