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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
NPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEYVRVQRQKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETAA
EKKERLTKEAAAVAEAKSKQDASPKPYAVKYGLNHVVALIENKKAKLVLIANDVDPIELVVFLPALCKKMGVPYAIVKGK
ARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTIDANFADKYDEVKKHWGGGILGNKAQAKMDKRAKNSDSA

The query sequence (length=233) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 8aaf:p 233 233 0.9957 0.9957 0.9957 5.58e-172 8agt:p, 8agu:p, 8agv:p, 8agw:p, 8agx:p, 8agz:p, 5apn:G, 5apo:G, 7azy:b, 7b7d:LJ, 8bip:LG, 8bjq:LG, 8bn3:L8, 8bqd:AA, 8bqx:AA, 7bt6:G, 7btb:G, 6c0f:G, 6cb1:G, 8ccs:KK, 8cdl:KK, 8cdr:KK, 8ceh:KK, 8cf5:KK, 8cg8:KK, 8cgn:KK, 8civ:KK, 8cku:KK, 8cmj:KK, 5dat:L8, 5dat:l8, 5dc3:L8, 5dc3:l8, 5dge:L8, 5dge:l8, 5dgf:L8, 5dgf:l8, 5dgv:L8, 5dgv:l8, 8e5t:G, 6elz:G, 6em1:G, 6em3:G, 6em4:G, 6em5:G, 8eub:AG, 8evp:AG, 8evq:AG, 8evr:AG, 8evs:AG, 8evt:AG, 8ewb:AG, 8ewc:AG, 5fci:L8, 5fci:l8, 5fcj:L8, 5fcj:l8, 6ft6:G, 5gak:K, 6gq1:G, 6gqb:G, 6gqv:G, 5h4p:G, 6hd7:K, 8hfr:Hj, 6hhq:p, 6hhq:CJ, 5i4l:L8, 5i4l:l8, 6i7o:AA, 6i7o:XA, 3j6x:L8, 3j6y:L8, 3j77:L8, 3j78:L8, 3jct:G, 5jcs:G, 5juo:L, 5jup:L, 5jus:L, 5jut:L, 5juu:L, 8k2d:LG, 8k82:LG, 5lyb:L8, 5lyb:l8, 5m1j:G5, 6m62:G, 5mc6:AA, 5mei:p, 5mei:CJ, 7mpi:AG, 7mpj:AG, 6n8j:G, 6n8k:G, 6n8l:G, 6n8m:J, 6n8n:J, 6n8o:J, 7n8b:AG, 7nac:G, 5ndg:L8, 5ndg:l8, 5ndv:L8, 5ndv:l8, 5ndw:L8, 5ndw:l8, 7nrc:LJ, 7nrd:LJ, 5obm:L8, 5obm:l8, 7of1:G, 7oh3:G, 7ohp:G, 7ohq:G, 7ohr:G, 7ohs:G, 7ohu:G, 7ohv:G, 7ohw:G, 7ohx:G, 7ohy:G, 6oig:G, 5on6:p, 5on6:CJ, 7osa:eL8, 7osm:eL8, 8p8m:LL, 8p8n:LL, 8p8u:LL, 8pfr:LL, 6q8y:AA, 6qik:H, 6qt0:H, 6qtz:H, 7r6q:G, 7r7a:G, 6r84:K, 6r86:K, 6r87:K, 6ri5:H, 7rr5:LG, 6rzz:H, 6s05:H, 6s47:AJ, 6snt:n, 6sv4:AA, 6sv4:XA, 6sv4:zA, 6t4q:LG, 5t62:J, 5t6r:J, 6t7i:LG, 6t7t:LG, 6t83:Gy, 6t83:Ja, 5tbw:p, 5tbw:CJ, 6tb3:AA, 5tga:L8, 5tga:l8, 5tgm:L8, 5tgm:l8, 6tnu:AA, 7too:AL08, 7top:AL08, 7u0h:G, 4u3m:L8, 4u3m:l8, 4u3n:L8, 4u3n:l8, 4u3u:L8, 4u3u:l8, 4u4n:L8, 4u4n:l8, 4u4o:L8, 4u4o:l8, 4u4q:L8, 4u4q:l8, 4u4r:L8, 4u4r:l8, 4u4u:L8, 4u4u:l8, 4u4y:L8, 4u4y:l8, 4u4z:L8, 4u4z:l8, 4u50:L8, 4u50:l8, 4u51:L8, 4u51:l8, 4u52:L8, 4u52:l8, 4u53:L8, 4u53:l8, 4u55:L8, 4u55:l8, 4u56:L8, 4u56:l8, 4u6f:L8, 4u6f:l8, 7ug6:G, 7uoo:G, 7uqb:G, 7uqz:G, 7v08:G, 4v4b:BG, 4v6i:BH, 4v7h:BG, 4v7r:BH, 4v7r:DH, 4v88:BG, 4v88:DG, 4v8t:G, 4v8y:BG, 4v8z:BG, 8v83:G, 8v84:G, 8v87:G, 4v91:G, 6woo:G, 6xiq:G, 6xir:G, 8y0u:LG, 6ylg:G, 6ylh:G, 6ylx:G, 6yly:G, 5z3g:K, 7z34:G, 6z6j:LG, 6z6k:LG, 7zpq:BG, 7zrs:BG, 7zs5:BI, 7zuw:BG, 7zux:EG, 7zw0:LK
2 5it7:GG 233 233 0.8584 0.8584 0.8584 2.86e-150 6uz7:AG
3 8c3a:p 238 217 0.7554 0.7395 0.8111 1.25e-133 8c3a:BC, 8cq7:p, 8cq7:BC, 8cqw:p, 8cqw:BC, 8cre:p, 8cre:BC, 8oeq:p, 8oeq:BC, 7pzy:p, 7q08:p, 7q0f:p, 7q0p:p, 7q0r:p, 8q5i:p
4 8eug:G 230 228 0.7167 0.7261 0.7325 1.49e-123 8esq:G, 8esr:G, 8etc:G, 8etg:G, 8eth:G, 8eti:G, 8etj:G, 8eui:G, 8eup:G, 8euy:G, 8ev3:G
5 7olc:LG 235 229 0.6910 0.6851 0.7031 9.52e-123 8i9p:LG, 8i9r:LG, 8i9t:LG, 8i9v:LG, 8i9w:LG, 8i9x:LG, 8i9y:LG, 8i9z:LG, 8ia0:LG, 7old:LG, 8oo0:LG, 8pv1:LG, 8pv2:LG, 8pv3:LG, 8pv4:LG, 8pv5:LG, 8pv6:LG, 8pv7:LG, 8pv8:LG, 8pvk:LG, 8pvl:LG, 7z3n:LG, 7z3o:LG
6 7r81:J1 236 233 0.6996 0.6907 0.6996 5.88e-122
7 4v7e:CG 237 228 0.5794 0.5696 0.5921 5.20e-95 8ip8:AA, 8ipa:AA, 8ipb:AA, 8jiv:CG, 4v3p:LH
8 4v6x:CG 246 226 0.5708 0.5407 0.5885 3.75e-94 7a01:V2, 8a3d:n, 5aj0:AG, 8b5l:G, 8b6c:G, 9bdl:AL08, 9bdn:AL08, 9bdp:AL08, 7bhp:LG, 8bhf:p3, 8bpo:G2, 8btk:BG, 7cpu:LG, 7cpv:LG, 4d5y:G, 4d67:G, 6d90:G, 6d9j:G, 9f1b:BG, 9f1c:BG, 9f1d:BG, 7f5s:LG, 8fkp:SE, 8fkq:SE, 8fkr:SE, 8fks:SE, 8fkt:SE, 8fku:SE, 8fkv:SE, 8fkw:SE, 8fkx:SE, 8fky:SE, 8fkz:SE, 8fl2:SE, 8fl3:SE, 8fl4:SE, 8fl6:SE, 8fl7:SE, 8fl9:SE, 8fla:SE, 8flb:SE, 8flc:SE, 8fld:SE, 8fle:SE, 8flf:SE, 6frk:G, 6ftg:G, 6fti:G, 6ftj:G, 8g5y:LG, 8g5z:LG, 8g60:LG, 8g61:LG, 8g6j:LG, 8glp:LG, 6gz3:AG, 6gz4:AG, 6gz5:AG, 6hcf:G3, 6hcj:G3, 6hcm:G3, 6hcq:G3, 8idt:G, 8idy:G, 8ie3:G, 8ifd:2B, 8ife:2B, 8ine:G, 8inf:G, 8ink:G, 6ip5:2B, 6ip6:2B, 6ip8:2B, 8ipd:G, 8ipx:G, 8ipy:G, 8ir1:G, 8ir3:G, 3j7o:G, 3j7p:G, 3j7q:G, 3j7r:G, 3j92:G, 3jag:G, 3jah:G, 3jai:G, 3jaj:G, 3jan:G, 8jdj:M, 8jdk:M, 8jdl:M, 8jdm:M, 8k2c:LG, 5lks:LG, 6lqm:G, 6lsr:G, 6lss:G, 7ls1:B1, 7ls2:B1, 6lu8:G, 5lzs:G, 5lzt:G, 5lzu:G, 5lzv:G, 5lzw:G, 5lzx:G, 5lzy:G, 5lzz:G, 7mdz:G, 6mtb:G, 6mtc:G, 6mtd:G, 6mte:G, 7nfx:G, 7nwg:G3, 7nwh:G, 7nwi:G, 7o7y:BG, 7o7z:BG, 7o80:BG, 7o81:BG, 7obr:G, 8ohd:LG, 8oj0:LG, 8oj5:LG, 8oj8:LG, 6ole:I, 6olf:I, 6olg:AG, 6oli:I, 6olz:AG, 6om0:I, 6om7:I, 7ow7:n, 7oya:G1, 7oyb:G1, 7oyc:G1, 7oyd:G, 8p2k:BG, 6p5i:AG, 6p5j:AG, 6p5k:AG, 6p5n:AG, 8q7z:BG, 8q87:BG, 8qfd:G, 7qgg:I, 8qoi:LG, 7qvp:MG, 7qvp:LG, 7qwq:G, 7qwr:G, 7qws:G, 6qzp:LG, 6r5q:G, 6r6g:G, 6r6p:G, 6r7q:G, 8rjb:G, 8rjc:G, 8rjd:G, 8scb:G, 6sgc:G2, 6swa:G, 5t2c:n, 6t59:G3, 7tm3:G, 7toq:AL08, 7tor:AL08, 7tut:G, 7ucj:G, 7uck:G, 4ug0:LG, 4ujc:BG, 4ujd:AG, 4uje:CG, 4v5z:Bf, 6w6l:I, 6xa1:LG, 7xnx:LG, 7xny:LG, 8xsx:LG, 8xsy:LG, 8xsz:LG, 6y0g:LG, 8y0w:LG, 8y0x:LG, 6y2l:LG, 6y57:LG, 6y6x:LG, 8yoo:LG, 8yop:LG, 6z6l:LG, 6z6m:LG, 6z6n:LG, 7zjw:LJ, 7zjx:LJ, 6zm7:LG, 6zme:LG, 6zmi:LG, 6zmo:LG, 6zvk:V2
9 4v6w:CG 241 238 0.5837 0.5643 0.5714 2.39e-90 6xu6:CG, 6xu7:CG, 6xu8:CG
10 8azw:c 233 222 0.5322 0.5322 0.5586 2.68e-90 8b2l:c3, 7qiw:J, 7qiz:J
11 4v8p:BF 231 228 0.5365 0.5411 0.5482 1.96e-85 4v8p:CF, 4v8p:EF, 4v8p:GF
12 9bh5:CG 221 222 0.4807 0.5068 0.5045 7.93e-83 9cai:CG
13 5xxb:G 233 228 0.4936 0.4936 0.5044 4.21e-75
14 6zj3:LV 238 210 0.4421 0.4328 0.4905 3.38e-69
15 8rxh:LG 241 224 0.4378 0.4232 0.4554 1.23e-66 8a3w:G, 8a98:G, 6az3:G, 3jcs:G, 8ovj:G, 8rxx:LG, 5t2a:v
16 4v8m:Bx 240 223 0.4421 0.4292 0.4619 8.44e-66 8ova:Bx, 8ove:Bx, 5t5h:x
17 3j79:J 229 236 0.4378 0.4454 0.4322 5.52e-61 3jbn:AJ, 3jbo:AJ, 3jbp:AJ, 8tpu:AJ, 5umd:J
18 5xy3:G 174 196 0.3691 0.4943 0.4388 7.23e-53
19 8fru:G 197 193 0.3820 0.4518 0.4611 1.32e-52 8br8:LI, 8brm:LI, 8bsi:LI, 8bsj:LI, 8btd:LI, 8btr:LI, 7pwg:G, 7pwo:G2
20 6zu5:LG0 202 170 0.3348 0.3861 0.4588 1.87e-49
21 7qep:L8 197 167 0.3391 0.4010 0.4731 2.81e-48
22 6rm3:LG0 195 171 0.3133 0.3744 0.4269 1.26e-44
23 8p5d:LG0 199 167 0.2876 0.3367 0.4012 2.33e-40 8p60:LG0, 8p60:KG0, 7qca:LG0
24 7r6k:G 52 34 0.1459 0.6538 1.0000 1.61e-17
25 7r6k:G 52 21 0.0773 0.3462 0.8571 9.38e-07
26 6k0a:I 116 97 0.1674 0.3362 0.4021 2.01e-11 6k0a:J, 6k0b:I, 6k0b:J, 1sds:A, 1sds:C, 1sds:B
27 6q8u:C 122 87 0.1545 0.2951 0.4138 2.03e-10 4bw0:B, 4c4w:C, 4c4w:G, 5fj4:C, 5fj4:G, 5g4u:C, 5g4u:D, 5g4u:G, 5g4u:H, 5g4u:K, 5g4u:L, 5g4v:C, 5g4v:D, 5g4v:G, 5g4v:H, 6hct:C, 6hct:D, 6hct:G, 6q8u:D, 1rlg:A, 1rlg:B
28 5y7m:A 125 56 0.1073 0.2000 0.4464 2.15e-09 4by9:G, 4by9:J, 4by9:D, 4by9:M, 5dcv:A, 5dcv:C, 3hax:D, 3hay:D, 3hjw:C, 2hvy:D, 5jb3:3, 5jbh:3, 3lwo:C, 3lwp:C, 3lwq:C, 3lwr:C, 3lwv:C, 3nmu:G, 3nmu:C, 3nvi:B, 3nvi:D, 3nvk:E, 3nvk:H, 7ozq:B, 7ozq:D, 7ozq:C, 7ozq:A, 6skf:BH, 6skf:BI, 6skg:BH, 6skg:BI, 6sw9:3, 6swc:3, 6swe:3, 6th6:BH, 6th6:BI, 6tph:A, 4v4n:B3, 4v4n:AG, 4v6u:A3, 4v6u:BG, 4v6u:B4, 5xtm:A, 5xtm:C, 5y7m:C, 7zag:3, 7zah:3, 7zai:3, 7zhg:3
29 6tmf:b 123 56 0.1073 0.2033 0.4464 3.12e-09
30 5gin:C 122 72 0.1288 0.2459 0.4167 4.39e-09 5gin:D, 5gin:L, 5gio:C, 5gio:D, 5gio:L, 5gip:C, 5gip:D, 5gip:M, 5gip:N, 3id5:C, 3id5:G, 5jpq:U, 5jpq:V, 3pla:C, 3pla:D, 3pla:L
31 8hku:L7A1 123 65 0.1116 0.2114 0.4000 7.87e-09 8hku:L7A2, 8hkv:L7A1, 8hkv:L7A2, 8hkx:SL7A, 8hky:L7A1, 8hky:L7A2, 8hky:SL7A, 8hkz:L7A1, 8hkz:L7A2, 8hkz:SL7A, 8hl1:SL7A, 8hl1:L7A1, 8hl1:L7A2, 8hl2:L7A1, 8hl2:L7A2, 8hl2:SL7A, 8hl3:L7A1, 8hl3:L7A2, 8hl3:SL7A, 8hl4:L7A1, 8hl4:L7A2, 8hl4:SL7A, 8hl5:L7A1, 8hl5:L7A2, 8hl5:SL7A, 8wkp:SL7A, 8wq2:SL7A, 8wq4:SL7A
32 3cc2:F 119 73 0.1245 0.2437 0.3973 2.54e-08 3cc4:F, 3cc7:F, 3cce:F, 3ccj:F, 3ccl:F, 3ccm:F, 3ccq:F, 3ccr:F, 3ccs:F, 3ccu:F, 3ccv:F, 3cd6:F, 3cma:F, 3cme:F, 3cpw:F, 3cxc:F, 3g4s:F, 3g6e:F, 3g71:F, 3i55:F, 3i56:F, 1jj2:F, 1k73:H, 1k8a:H, 1k9m:H, 1kc8:H, 1kd1:H, 1kqs:F, 1m1k:H, 1m90:H, 1n8r:H, 1nji:H, 2otj:F, 2otl:F, 3ow2:F, 1q7y:H, 1q81:H, 1q82:H, 1q86:H, 2qa4:F, 2qex:F, 1qvf:F, 1qvg:F, 1s72:F, 4v9f:F, 1vq4:F, 1vq5:F, 1vq6:F, 1vq7:F, 1vq8:F, 1vq9:F, 1vqk:F, 1vql:F, 1vqm:F, 1vqn:F, 1vqo:F, 1vqp:F, 1w2b:F, 1yhq:F, 1yi2:F, 1yij:F, 1yit:F, 1yj9:F, 1yjn:F, 1yjw:F
33 5oql:V 121 77 0.0987 0.1901 0.2987 1.85e-05 5oql:W, 6rxt:CE, 6rxt:CF, 6rxu:CE, 6rxu:CF, 6rxv:CE, 6rxv:CF, 6rxx:CE, 6rxx:CF, 6rxy:CE, 6rxy:CF, 6rxz:CE, 6rxz:CF
34 2ale:A 132 68 0.0858 0.1515 0.2941 3.09e-05 7ajt:CF, 7ajt:CG, 7aju:CF, 7aju:CG, 7d4i:3G, 7d4i:3H, 7d5s:3G, 7d5s:3H, 7d5t:3G, 7d5t:3H, 7d63:3G, 7d63:3H, 5gan:K, 5gap:K, 3jcm:M, 6ke6:3G, 6ke6:3H, 6lqp:3G, 6lqp:3H, 6lqq:3G, 6lqq:3H, 6lqr:3G, 6lqr:3H, 6lqs:3G, 6lqs:3H, 6lqt:3G, 6lqt:3H, 6lqu:3G, 6lqu:3H, 6lqv:3G, 6lqv:3H, 6nd4:e, 6nd4:f, 5nrl:K, 4nut:A, 7suk:SE, 7suk:SF, 5tzs:f, 5wlc:SE, 5wlc:SF, 5wyj:3G, 5wyj:3H, 5wyk:3G, 5wyk:3H, 6zqa:CF, 6zqb:CF, 6zqb:CG, 6zqc:CF, 6zqc:CG, 6zqd:CF, 6zqd:CG, 6zqe:CF, 6zqe:CG, 5zwm:M, 5zwo:M
35 3siv:A 128 56 0.0730 0.1328 0.3036 4.45e-05 6ah0:M, 6ahd:M, 1e7k:A, 1e7k:B, 8h6e:4E, 8h6j:4E, 8h6k:4E, 8h6l:4E, 7mq8:SE, 7mq8:SF, 7mq9:SE, 7mq9:SF, 7mqa:SE, 7mqa:SF, 5o9z:O, 2ozb:A, 2ozb:D, 8q7n:M, 8qo9:M, 8qoz:M, 8qpa:M, 8qpb:M, 8qpe:M, 6qw6:4D, 6qx9:4D, 8qxd:M, 8qzs:M, 8r08:M, 8r09:M, 8r0a:M, 8r0b:M, 8rm5:M, 3siu:A, 3siu:D, 3siv:D, 3siv:J, 3siv:G, 8y6o:O
36 4bts:AU 124 92 0.1245 0.2339 0.3152 1.38e-04 4bts:BU, 4bts:CU, 4bts:DU, 4v5o:AU, 4v5o:BU
37 7v9a:I 134 89 0.0773 0.1343 0.2022 3.21e-04 7bgb:I, 8oue:I, 8ouf:I, 7trc:I
38 5xyi:M 103 69 0.0901 0.2039 0.3043 1.0
39 4f9j:A 599 51 0.0773 0.0301 0.3529 2.3 4f9d:A, 4f9d:B, 4f9j:B, 4p7n:A, 4p7q:A, 4p7r:A, 3vus:A, 3vus:B
40 8auv:C 117 53 0.0730 0.1453 0.3208 3.3 8b2l:C1
41 5z0c:A 367 109 0.1288 0.0817 0.2752 3.5
42 8fvy:M 103 60 0.0773 0.1748 0.3000 3.6 8g4s:M
43 2x75:A 427 54 0.0601 0.0328 0.2593 3.8
44 4v7e:BM 123 53 0.0730 0.1382 0.3208 5.7 8r57:M
45 3uk2:A 280 36 0.0644 0.0536 0.4167 7.8 3uk2:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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