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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLQHMLFLGTKKYP
KENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLF
QLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKN
VPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGG
QKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILH
YYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKF
KLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKD
SLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHA
MYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQ
LVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANG
IQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDN
TEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH

The query sequence (length=954) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2g49:A 970 965 0.9885 0.9722 0.9772 0.0 6b3q:A, 6b3q:B, 6b70:A, 6b70:B, 6bfc:A, 6bfc:B, 6byz:A, 6byz:B, 5cjo:A, 3cww:B, 3cww:A, 4dtt:A, 4dtt:B, 4dwk:A, 4dwk:B, 3e4a:A, 3e4a:B, 3e4z:A, 3e4z:B, 3e50:A, 3e50:B, 6eds:A, 6eds:B, 2g47:A, 2g47:B, 2g48:A, 2g48:B, 2g49:B, 2g54:A, 2g54:B, 2g56:A, 2g56:B, 4gs8:A, 4gs8:B, 4gsc:A, 4gsc:B, 4gsf:A, 4gsf:B, 3h44:A, 3h44:B, 3hgz:A, 3hgz:B, 4ifh:A, 4ifh:B, 2jbu:A, 2jbu:B, 2jg4:A, 2jg4:B, 7k1d:A, 7k1d:B, 7k1e:A, 7k1e:B, 7k1f:A, 7k1f:B, 4lte:A, 4lte:B, 4m1c:A, 4m1c:B, 6mq3:A, 6mq3:B, 3n56:A, 3n56:B, 3n57:A, 3n57:B, 4nxo:A, 4nxo:B, 3ofi:A, 3ofi:B, 3p7l:A, 3p7o:A, 4pes:A, 4pes:B, 4pf7:A, 4pf7:B, 4pf9:A, 4pf9:B, 4pfc:A, 4pfc:B, 4qia:A, 4qia:B, 3qz2:A, 3qz2:B, 4ral:A, 4ral:B, 4re9:A, 4re9:B, 7rze:A, 7rzf:A, 7rzi:A, 7rzi:B, 3tuv:A, 2wby:A, 2wby:B, 2wc0:A, 2wc0:B, 2wk3:A, 2wk3:B, 5wob:A, 5wob:B, 5wob:C, 5wob:D, 5wob:E, 5wob:F, 5wob:G, 5wob:H, 2ypu:A, 2ypu:B
2 4iof:A 932 954 0.9738 0.9968 0.9738 0.0
3 1q2l:A 937 900 0.2621 0.2668 0.2778 4.94e-110
4 5cio:A 770 345 0.0849 0.1052 0.2348 1.88e-18 5cio:B
5 5cio:A 770 105 0.0262 0.0325 0.2381 0.26 5cio:B
6 7v4y:A 402 318 0.0881 0.2090 0.2642 3.52e-11
7 7jrg:A 487 218 0.0566 0.1109 0.2477 4.79e-11 8e73:A, 8e73:M, 7jrg:M, 7jrp:A, 7jrp:M
8 8bep:B 487 230 0.0608 0.1191 0.2522 8.42e-11 8bep:L, 8bpx:AB, 8bpx:BB, 8bq5:AB, 8bq5:BB, 8bq6:AB, 8bq6:BB
9 3hdi:A 414 119 0.0419 0.0966 0.3361 9.50e-11 3hdi:B
10 6ofs:A 905 349 0.0901 0.0950 0.2464 1.42e-10
11 8q1b:A 443 213 0.0618 0.1332 0.2770 5.99e-10 8q1b:L
12 1hr6:D 443 129 0.0409 0.0880 0.3023 4.68e-09 1hr6:B, 1hr6:F, 1hr6:H, 1hr7:B, 1hr7:D, 1hr7:F, 1hr7:H, 1hr8:B, 1hr8:D, 1hr8:F, 1hr8:H, 1hr9:B, 1hr9:D, 1hr9:F, 1hr9:H
13 3amj:C 422 194 0.0514 0.1161 0.2526 9.60e-09 3amj:A
14 5euf:B 416 239 0.0671 0.1538 0.2678 9.94e-08 5euf:A
15 1be3:A 446 335 0.0776 0.1659 0.2209 5.91e-04 2a06:A, 1bgy:A, 1bgy:M, 4d6t:N, 4d6u:A, 4d6u:N, 7dgq:k, 7dgq:w, 7dgr:k, 7dgr:w, 7dgs:k, 7dgs:w, 7dkf:A1, 7dkf:M1, 6fo0:N, 6fo0:A, 6fo2:N, 6fo2:A, 5luf:c, 5luf:l, 5nmi:N, 5nmi:A, 1pp9:A, 1ppj:A, 6qbx:a3, 6qc3:a1, 7tz6:A, 7tz6:N, 2ybb:a, 2ybb:A
16 6b03:A 896 240 0.0608 0.0647 0.2417 0.005 6b05:A, 6brs:A
17 4rpu:A 988 57 0.0189 0.0182 0.3158 0.011 4l3t:A, 4l3t:B, 4nge:A, 4nge:D, 4rpu:B
18 8iao:Aa 412 212 0.0472 0.1092 0.2123 0.033 8iar:Aa, 8ibd:AA, 8ibd:Aa, 8ibg:AA, 8ibg:Aa
19 6xov:A 966 55 0.0178 0.0176 0.3091 0.036
20 3go9:A 458 265 0.0556 0.1157 0.2000 0.052
21 7o3e:L 445 212 0.0472 0.1011 0.2123 0.060
22 2fge:A 979 51 0.0178 0.0174 0.3333 0.27 2fge:B
23 5ji5:A 305 48 0.0199 0.0623 0.3958 1.6
24 5khl:B 257 63 0.0220 0.0817 0.3333 2.3
25 8x6f:D 1176 50 0.0178 0.0145 0.3400 5.4 8x6g:D
26 3suc:A 767 127 0.0356 0.0443 0.2677 8.3 3gq7:A, 3gq8:A, 3gqa:A, 3gqk:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218