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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLEHMLFLGTKKYP
KENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLF
QLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKN
VPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGG
QKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILH
YYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKF
KLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKD
SLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHA
MYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQ
LVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANG
IQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDN
TEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH

The query sequence (length=956) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2g49:A 970 965 0.9874 0.9732 0.9782 0.0 6b3q:A, 6b3q:B, 6b70:A, 6b70:B, 6bfc:A, 6bfc:B, 6byz:A, 6byz:B, 5cjo:A, 3cww:B, 3cww:A, 4dtt:A, 4dtt:B, 4dwk:A, 4dwk:B, 3e4a:A, 3e4a:B, 3e4z:A, 3e4z:B, 3e50:A, 3e50:B, 6eds:A, 6eds:B, 2g47:A, 2g47:B, 2g48:A, 2g48:B, 2g49:B, 2g54:A, 2g54:B, 2g56:A, 2g56:B, 4gs8:A, 4gs8:B, 4gsc:A, 4gsc:B, 4gsf:A, 4gsf:B, 3h44:A, 3h44:B, 3hgz:A, 3hgz:B, 4ifh:A, 4ifh:B, 2jbu:A, 2jbu:B, 2jg4:A, 2jg4:B, 7k1d:A, 7k1d:B, 7k1e:A, 7k1e:B, 7k1f:A, 7k1f:B, 4lte:A, 4lte:B, 4m1c:A, 4m1c:B, 6mq3:A, 6mq3:B, 3n56:A, 3n56:B, 3n57:A, 3n57:B, 4nxo:A, 4nxo:B, 3ofi:A, 3ofi:B, 3p7l:A, 3p7o:A, 4pes:A, 4pes:B, 4pf7:A, 4pf7:B, 4pf9:A, 4pf9:B, 4pfc:A, 4pfc:B, 4qia:A, 4qia:B, 3qz2:A, 3qz2:B, 4ral:A, 4ral:B, 4re9:A, 4re9:B, 7rze:A, 7rzf:A, 7rzi:A, 7rzi:B, 3tuv:A, 2wby:A, 2wby:B, 2wc0:A, 2wc0:B, 2wk3:A, 2wk3:B, 5wob:A, 5wob:B, 5wob:C, 5wob:D, 5wob:E, 5wob:F, 5wob:G, 5wob:H, 2ypu:A, 2ypu:B
2 4iof:A 932 954 0.9749 1.0000 0.9769 0.0
3 1q2l:A 937 900 0.2626 0.2679 0.2789 1.96e-110
4 5cio:A 770 345 0.0858 0.1065 0.2377 6.72e-19 5cio:B
5 5cio:A 770 105 0.0262 0.0325 0.2381 0.24 5cio:B
6 7v4y:A 402 318 0.0889 0.2114 0.2673 1.66e-11
7 7jrg:A 487 218 0.0575 0.1129 0.2523 2.16e-11 8e73:A, 8e73:M, 7jrg:M, 7jrp:A, 7jrp:M
8 8bep:B 487 230 0.0617 0.1211 0.2565 3.36e-11 8bep:L, 8bpx:AB, 8bpx:BB, 8bq5:AB, 8bq5:BB, 8bq6:AB, 8bq6:BB
9 3hdi:A 414 119 0.0429 0.0990 0.3445 3.37e-11 3hdi:B
10 6ofs:A 905 349 0.0910 0.0961 0.2493 4.55e-11
11 8q1b:A 443 213 0.0628 0.1354 0.2817 2.40e-10 8q1b:L
12 1hr6:D 443 129 0.0418 0.0903 0.3101 2.02e-09 1hr6:B, 1hr6:F, 1hr6:H, 1hr7:B, 1hr7:D, 1hr7:F, 1hr7:H, 1hr8:B, 1hr8:D, 1hr8:F, 1hr8:H, 1hr9:B, 1hr9:D, 1hr9:F, 1hr9:H
13 3amj:C 422 194 0.0523 0.1185 0.2577 3.26e-09 3amj:A
14 5euf:B 416 239 0.0680 0.1562 0.2720 3.57e-08 5euf:A
15 1be3:A 446 335 0.0785 0.1682 0.2239 2.33e-04 2a06:A, 1bgy:A, 1bgy:M, 4d6t:N, 4d6u:A, 4d6u:N, 7dgq:k, 7dgq:w, 7dgr:k, 7dgr:w, 7dgs:k, 7dgs:w, 7dkf:A1, 7dkf:M1, 6fo0:N, 6fo0:A, 6fo2:N, 6fo2:A, 5luf:c, 5luf:l, 5nmi:N, 5nmi:A, 1pp9:A, 1ppj:A, 6qbx:a3, 6qc3:a1, 7tz6:A, 7tz6:N, 2ybb:a, 2ybb:A
16 6b03:A 896 242 0.0596 0.0636 0.2355 0.002 6b05:A, 6brs:A
17 8iao:Aa 412 212 0.0481 0.1117 0.2170 0.013 8iar:Aa, 8ibd:AA, 8ibd:Aa, 8ibg:AA, 8ibg:Aa
18 6xov:A 966 55 0.0188 0.0186 0.3273 0.014
19 7o3e:L 445 212 0.0481 0.1034 0.2170 0.022
20 4rpu:A 988 55 0.0178 0.0172 0.3091 0.027 4l3t:A, 4l3t:B, 4nge:A, 4nge:D, 4rpu:B
21 3go9:A 458 265 0.0554 0.1157 0.2000 0.041
22 2fge:A 979 51 0.0167 0.0163 0.3137 0.81 2fge:B
23 5ji5:A 305 48 0.0199 0.0623 0.3958 1.6
24 5khl:B 257 63 0.0220 0.0817 0.3333 2.3
25 8x6f:D 1176 50 0.0178 0.0145 0.3400 5.3 8x6g:D
26 3suc:A 767 127 0.0356 0.0443 0.2677 8.6 3gq7:A, 3gq8:A, 3gqa:A, 3gqk:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218