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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NLWVTVYYGVPVWKDAETTLFCASDAKAYETEKHNVWATHACVPTDPNPQEIHLENVTEEFNMWKNNMVEQMHTDIISLW
DQSLKPCVKLTPLCVTYRLINCNTSAITQACPKVSFEPIPIHYCAPAGFAILKCKDKKFNGTGPCPSVSTVQCTHGIKPV
VSTQLLLNGSLAEEEVMIRSENITNNAKNILVQFNTPVQINCTRPNDIRQAHCNVSKATWNETLGKVVKQLRKHFGNNTI
IRFANSSGGDLEVTTHSFNCGGEFFYCNTSGLFNSTWISDSITLPCRIKQIINMWQRIGQAMYAPPIQGVIRCVSNITGL
ILTRDGGSTTETFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTRCK

The query sequence (length=367) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6cm3:D 372 372 0.9973 0.9839 0.9839 0.0 6cm3:E, 6cm3:F, 7lo6:C, 7lo6:A, 7lo6:E, 7lok:A, 7lok:C, 7lok:E, 6u0l:B, 6u0l:C, 6u0n:A, 6u0n:C
2 7txd:A 397 396 0.9946 0.9194 0.9217 0.0 7txd:E
3 8d0y:G 455 449 0.9837 0.7934 0.8040 0.0 5cez:G, 6ch8:G, 6de7:G, 5i8h:A, 5i8h:C, 7l7u:A, 7l7u:C, 7l7u:E, 6mtj:G, 6mtn:G, 6mu6:G, 6mu7:G, 6mu8:G, 7pc2:A, 7rai:A, 7rai:C, 7rai:E, 8s2e:E, 5t3z:G, 8tjr:B, 8tjr:C, 8tjs:G, 8tjs:N, 8tjs:O, 8ttw:E, 8ttw:I, 8ttw:A, 4tvp:G, 5u7m:G, 5u7o:G, 7ucf:G, 5utf:G, 5v7j:G, 4zmj:G
4 6opp:A 389 384 0.8202 0.7738 0.7839 0.0 6opo:A, 6opo:D, 6opo:J, 6opp:D, 6opp:J, 6opq:A, 6opq:D, 6opq:E, 5vn3:G, 5vn3:I, 5vn3:J
5 6meo:G 398 398 0.8011 0.7387 0.7387 0.0 6met:G
6 4xmp:G 337 350 0.7929 0.8635 0.8314 0.0
7 8czz:A 440 440 0.8011 0.6682 0.6682 0.0 8czz:E, 8czz:I
8 7n6u:B 595 445 0.8093 0.4992 0.6674 0.0 5fuu:A, 5fuu:D, 5fuu:E, 5fuu:F, 6j5e:K, 7n6u:C, 7n6u:A, 7n6w:A, 7n6w:B, 7n6w:C, 6olp:C, 7ska:B, 7ska:O, 7ska:Z, 6vpx:C, 5y14:C, 5y14:A, 5y14:B, 5yc0:B, 5yc0:C, 5yc0:F
9 6ch9:G 448 443 0.8256 0.6763 0.6840 0.0 6mug:G
10 8d53:G 446 441 0.8065 0.6637 0.6712 0.0
11 6edu:D 401 409 0.8065 0.7382 0.7237 0.0 6edu:E, 6edu:F
12 6x5b:A 353 371 0.7793 0.8102 0.7709 0.0 6opn:A, 6opn:D, 6opn:G, 6x5b:D, 6x5b:J, 6x5c:A, 6x5c:D, 6x5c:E
13 7lu9:e 461 458 0.7929 0.6312 0.6354 0.0 7lu9:f
14 4r4n:B 342 354 0.7684 0.8246 0.7966 0.0 4r4n:A, 4r4n:E, 4r4n:I, 4r4n:M, 4r4n:P, 4r4n:S, 4r4n:V
15 4j6r:G 343 357 0.7684 0.8222 0.7899 0.0
16 4laj:A 343 356 0.7357 0.7872 0.7584 0.0 4dvr:G, 2i5y:G, 2i5y:P, 2i60:G, 2i60:P, 4jzw:G, 4jzw:A, 4jzz:A, 4k0a:A, 4ka2:A, 4laj:J, 4laj:F, 4laj:B, 4r4f:A, 1yyl:G, 1yyl:P, 1yym:G, 1yym:P
17 5w4l:G 357 367 0.7221 0.7423 0.7221 0.0 6bf4:G, 8dcq:A, 4dko:A, 4dko:C, 4dkp:A, 4dkp:C, 4dkq:A, 4dkr:A, 4dkr:C, 4dku:A, 4dku:B, 4dkv:A, 4dkv:B, 4dvs:A, 4dvs:B, 4dvt:A, 4dvt:B, 4dvv:A, 4dvv:B, 4dvw:A, 4dvw:B, 4dvx:A, 4dvx:B, 8f9z:A, 8fa0:A, 8gcz:A, 8gd0:A, 8gd1:A, 8gd3:A, 8gd5:A, 8gdj:A, 8gdk:A, 8gjt:A, 4i54:A, 4i54:B, 5kjr:G, 4lsq:G, 6mfp:G, 6mfp:A, 6mg7:G, 7n8q:G, 3ngb:G, 3ngb:A, 3ngb:D, 3ngb:I, 6one:A, 6onf:A, 6onh:A, 6onv:A, 6ooo:A, 6p9n:A, 4rfn:G, 4rfn:A, 4rfo:G, 4rz8:A, 4rz8:B, 4rz8:C, 4rz8:D, 3se9:G, 5u6e:A, 5u6e:B, 5uem:G, 6usw:A, 6ut1:A, 5w4l:A, 6w4m:G
18 8fae:A 468 463 0.7793 0.6111 0.6177 0.0 8fad:C, 8fad:E, 8fad:A, 8fae:C, 8fae:E
19 3tgs:A 345 357 0.7084 0.7536 0.7283 0.0 5f4l:A, 5f4l:B, 5f4p:D, 5f4p:A, 5f4r:A, 5f4r:C, 5f4u:A, 5f4u:B, 8fly:A, 8fly:B, 8fly:C, 8fly:D, 8flz:A, 8flz:D, 8flz:B, 8flz:C, 8fm0:B, 8fm0:A, 8fm0:C, 8fm0:D, 8fm2:D, 8fm2:B, 8fm2:A, 8fm2:C, 8fm3:A, 8fm3:C, 8fm3:D, 8fm3:B, 8fm4:B, 8fm4:D, 8fm4:A, 8fm4:C, 8fm5:D, 8fm5:A, 8fm5:C, 8fm5:B, 8fm7:A, 8fm7:B, 8fm7:C, 8fm7:D, 8fm8:C, 8fm8:D, 8fm8:A, 8fm8:B, 4i53:A, 4i53:B, 7rsx:C, 7rsx:B, 7rsx:A, 7rsx:D, 7rsy:A, 7rsy:B, 7rsy:C, 7rsy:D, 7rsz:B, 7rsz:A, 7rsz:C, 7rsz:D, 3tgs:B, 7tjo:D, 7tjo:A, 7tjo:C, 7tjo:B, 7tjp:A, 7tjp:B, 7tjp:D, 7tjp:C
20 6pwu:A 615 470 0.7793 0.4650 0.6085 0.0 6j5e:I, 6ulc:C, 6ulc:A, 3vtp:C, 5yb2:E, 5yb2:F, 5yb2:D, 5yb2:A, 5yb2:B, 5yb2:C, 5yb2:M, 5yb3:E, 5yb3:F, 5yb3:D, 5yc0:A, 5yc0:D, 5yc0:E, 5z0w:E, 5zcx:A, 5zpw:A, 5zpw:E, 5zpw:C
21 5te4:G 341 354 0.6975 0.7507 0.7232 0.0
22 5fa2:A 336 348 0.6649 0.7262 0.7011 0.0
23 8tgw:A 387 423 0.7248 0.6873 0.6288 1.99e-179
24 1gc1:G 297 304 0.6294 0.7778 0.7599 6.28e-170
25 5fyj:G 479 305 0.5559 0.4259 0.6689 1.37e-139
26 5fyj:G 479 96 0.2343 0.1795 0.8958 2.20e-56
27 7mxd:A 472 309 0.5395 0.4195 0.6408 4.95e-139 7mxd:F, 7mxd:G, 7n28:A
28 7mxd:A 472 101 0.2398 0.1864 0.8713 2.05e-57 7mxd:F, 7mxd:G, 7n28:A
29 6tyb:G 345 366 0.3188 0.3391 0.3197 3.24e-51 3fus:A
30 7t4g:A 493 308 0.2589 0.1927 0.3084 8.96e-38 7t4g:C, 7t4g:E
31 7t4g:A 493 104 0.1281 0.0953 0.4519 7.60e-20 7t4g:C, 7t4g:E
32 7ana:AAA 475 61 0.0490 0.0379 0.2951 0.11 7ana:BBB, 7anb:AAA, 7anb:BBB
33 6rmw:C 386 55 0.0436 0.0415 0.2909 0.67 6rmd:D, 6rme:A, 6rme:B, 6rme:C, 6rme:D, 6rme:E, 6rme:F, 6rme:G, 6rme:H, 6rmw:A, 6rmw:B, 6rmw:D, 6rmw:E, 6rmw:F, 6rmw:G, 6rmw:H
34 6tpq:B 183 84 0.0572 0.1148 0.2500 1.4 6tpq:A, 6z2b:B
35 2bdz:A 212 84 0.0599 0.1038 0.2619 3.9 2bdz:D, 2bdz:B, 2bdz:C
36 7rsw:B 125 28 0.0327 0.0960 0.4286 4.6
37 4dzh:A 439 145 0.0954 0.0797 0.2414 5.7
38 4z67:A 309 70 0.0490 0.0583 0.2571 6.6 6e13:A, 3jxp:A, 1xto:A, 4z5y:A, 4z5z:A, 4z60:A, 4z6x:A
39 5wn9:H 236 143 0.0899 0.1398 0.2308 7.4
40 1ece:A 358 52 0.0436 0.0447 0.3077 7.5 1ece:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218