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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSF
KAAERKLNTEETVQEWVDKIRKQVAPFLDFDCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQRLNRE
DQGISFTEFSYNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTKFGKAVWLDP
KKTSPYKFYQFWINTADADVYRFLKFFTFMSIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLQAAKRITECLF
SGSLSALSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAITINGEKQSDPEYFFKEEERLFGRF
TLLRRGKKNYCLICWK

The query sequence (length=416) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6hb5:B 417 417 1.0000 0.9976 0.9976 0.0 7ap3:A, 7ap3:B, 6hb5:A, 6hb6:A, 6hb6:B, 6hb7:A, 6hb7:B, 6i5y:A, 6i5y:B, 4oud:A, 1vbm:A, 1vbm:B, 1vbn:A, 1vbn:B, 6wn2:A, 6wn2:B, 1wq3:A, 1wq4:A, 1x8x:A, 2yxn:A
2 6otj:B 431 427 0.6418 0.6195 0.6253 0.0 6otj:A
3 3ts1:A 317 320 0.4591 0.6025 0.5969 4.43e-138 4ts1:A, 4ts1:B, 1tya:E, 1tyb:E, 1tyd:E
4 1jil:A 323 324 0.4014 0.5170 0.5154 9.27e-122 1jii:A, 1jij:A, 1jik:A
5 2pid:B 324 301 0.3005 0.3858 0.4153 1.20e-65 2pid:A, 3zxi:A, 3zxi:B
6 4ojm:X 382 345 0.2861 0.3115 0.3449 1.40e-63 2rkj:B, 2rkj:F, 2rkj:J, 2rkj:N, 1y42:X
7 5ihx:A 360 348 0.2644 0.3056 0.3161 2.29e-52
8 5ijx:A 365 334 0.2692 0.3068 0.3353 4.05e-48
9 6bqz:A 215 219 0.1659 0.3209 0.3151 4.28e-25 6bqz:B
10 1h3e:A 427 446 0.2716 0.2646 0.2534 2.08e-23
11 1h3f:B 406 432 0.2572 0.2635 0.2477 4.03e-20 1h3f:A
12 2cyb:A 319 203 0.1058 0.1379 0.2167 7.21e-05 2cyb:B
13 3kt8:D 410 60 0.0481 0.0488 0.3333 5.27e-04 3kt0:A, 3kt3:A, 3kt3:B, 3kt3:C, 3kt3:D, 3kt6:A, 3kt6:B, 3kt6:C, 3kt6:D, 3kt8:A, 3kt8:B, 3kt8:C
14 3tze:A 360 53 0.0457 0.0528 0.3585 0.002 3tze:B
15 3hv0:A 352 60 0.0481 0.0568 0.3333 0.005 3hv0:B
16 5ujj:A 446 39 0.0312 0.0291 0.3333 0.014 2ake:A, 2azx:A, 2azx:B, 2dr2:A, 2quh:A, 2quh:B, 2qui:A, 2qui:B, 2quj:A, 2quj:B, 1r6t:A, 1r6u:A, 5ujj:B
17 4jfa:C 348 60 0.0457 0.0546 0.3167 0.023
18 4j75:A 374 60 0.0457 0.0508 0.3167 0.026 4j75:B, 4jfa:A, 4jfa:B, 4jfa:D
19 5mrc:DD 287 96 0.0625 0.0906 0.2708 0.50 5mre:DD, 5mrf:DD
20 1hpl:A 449 119 0.0769 0.0713 0.2689 0.93 1hpl:B
21 7jil:i 194 40 0.0337 0.0722 0.3500 1.4
22 1h9t:A 232 30 0.0288 0.0517 0.4000 1.9 1h9g:A, 1h9t:B, 1hw2:A, 1hw2:B
23 5n0c:A 1293 49 0.0481 0.0155 0.4082 2.1 1dfq:A, 1diw:A, 1dll:A, 1fv2:A, 1fv3:A, 1fv3:B, 3hmy:A, 3hn1:A, 5n0b:A, 5n0c:B, 1yxw:A, 1yyn:A, 1z7h:A
24 3mhs:A 455 55 0.0337 0.0308 0.2545 3.4 6aqr:A, 4fip:A, 4fip:E, 4fjc:A, 4fk5:A, 6t9l:K, 4w4u:A, 4wa6:A, 4zux:U, 4zux:Z, 4zux:e, 4zux:j
25 8d8j:D 308 97 0.0721 0.0974 0.3093 6.3 8d8k:D
26 6yw5:DD 290 153 0.0962 0.1379 0.2614 7.4 6ywe:DD, 6ywx:DD, 6ywy:DD
27 5d9h:B 293 91 0.0601 0.0853 0.2747 8.9 5d9h:A, 5dbx:A, 5dbx:B
28 7xcm:A 494 60 0.0457 0.0385 0.3167 9.8 7xcm:B, 7xcm:C, 7xcm:D, 7xcm:E, 7xcm:F, 7xcn:A, 7xcn:B, 7xcn:C, 7xcn:D, 7xcn:E, 7xcn:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218