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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NKYRFIDVQPLTGVLGAEITGVDLREPLDDSTWNEILDAFHTYQVIYFPGQAITNEQHIAFSRRFGPVDPVPILKSIEGY
PEVQMIRREANESSRFIGDDWHTDSTFLDAPPAAVVMRAIEVPEYGGDTGFLSMYSAWETLSPTMQATIEGLNVVHSATK
VFGSLYQATNWRFSNTSVKVMDVDAGDRETVHPLVVTHPVTGRRALYCNQVYCQKIQGMTDAESKSLLQFLYEHATKFDF
TCRVRWKKDQVLVWDNLCTMHRAVPDYAGKFRYLTRTTVAGDKPSR

The query sequence (length=286) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6d3h:M 287 286 1.0000 0.9965 1.0000 0.0 6d3i:A
2 5bk9:A 289 286 0.9021 0.8927 0.9021 0.0 5bk9:B, 5bkb:A, 5bkb:B, 5bkc:A, 5bkd:A, 5bkd:B, 6d0o:A, 6d0o:C, 6d0o:D, 6d3h:A, 6d3h:B, 6d3h:I, 6d3i:G, 6d3i:D, 6d3i:J, 6d3m:A, 6d3m:B, 6d3m:F, 6d3m:J
3 5bkc:B 264 284 0.8392 0.9091 0.8451 0.0
4 6d3j:A 247 286 0.8636 1.0000 0.8636 0.0
5 6d0o:B 267 285 0.7832 0.8390 0.7860 1.93e-166
6 6edh:A 281 280 0.3392 0.3452 0.3464 1.22e-56 6edh:B, 1gqw:A, 1gqw:B, 1gy9:A, 1gy9:B, 1os7:A, 1os7:B, 1os7:C, 1os7:D
7 3v17:A 276 284 0.3462 0.3587 0.3486 3.46e-53 3v17:C, 3v17:B, 3v17:D
8 7qte:B 284 280 0.3566 0.3592 0.3643 5.23e-52 7qtd:A, 7qtd:B, 7qtd:C, 7qtd:D, 7qte:A, 7qtg:A, 7qtg:B
9 5keu:B 280 282 0.3706 0.3786 0.3759 1.00e-51 5keu:A
10 5vn6:A 273 288 0.3217 0.3370 0.3194 1.45e-40 5vn6:B
11 1vz4:D 259 280 0.3147 0.3475 0.3214 6.32e-39 1oii:A, 1oii:B, 1oii:D, 1oij:A, 1oij:B, 1oik:A, 1oik:D, 1vz4:A
12 1oij:C 238 279 0.3042 0.3655 0.3118 1.74e-37 1oii:C, 1oij:D
13 4y0e:H 308 282 0.3077 0.2857 0.3121 6.49e-35 4y0e:A, 4y0e:B, 4y0e:C, 4y0e:D, 4y0e:E, 4y0e:F, 4y0e:G
14 4j5i:B 285 281 0.3007 0.3018 0.3060 1.62e-34 4j5i:C, 4j5i:G
15 5bke:E 255 281 0.3042 0.3412 0.3096 2.12e-32 5bke:F, 5bke:G
16 4j5i:E 250 280 0.2692 0.3080 0.2750 3.99e-31 4j5i:A, 4j5i:D, 4j5i:F, 4j5i:H
17 5j92:B 259 281 0.2832 0.3127 0.2883 8.46e-31 5j92:A, 5j92:C, 5j92:D
18 8evo:B 242 280 0.2867 0.3388 0.2929 2.32e-30 4cvy:A, 4cvy:B, 4cvy:C, 4cvy:D
19 3r1j:A 246 280 0.2937 0.3415 0.3000 6.75e-30 3r1j:B
20 3swt:B 246 281 0.2797 0.3252 0.2847 6.97e-30 3swt:A
21 5bke:C 289 296 0.3112 0.3080 0.3007 2.78e-29 5bke:A, 5bke:B, 5bke:D
22 6l86:A 292 265 0.2343 0.2295 0.2528 6.03e-16 6l86:B, 6l86:C, 6l86:D
23 6dch:A 296 275 0.2413 0.2331 0.2509 9.86e-16 6l6w:A, 6l6x:A, 7scp:A, 6xn6:A, 6xo3:A, 6xoj:A, 6xpa:A
24 8kht:B 285 263 0.2343 0.2351 0.2548 4.65e-14 8kht:A
25 8kif:C 286 263 0.2343 0.2343 0.2548 1.48e-13 8kif:B, 8kif:A, 8kif:D
26 5jcy:A 371 82 0.0664 0.0512 0.2317 3.7 5jcz:C, 4kp3:A, 4kp3:B, 6ku0:A, 6ku0:C, 4lx2:A
27 5xss:A 274 71 0.0629 0.0657 0.2535 5.8 5xsj:X, 5xss:X, 5xss:B, 5xss:C
28 4ix7:A 114 45 0.0524 0.1316 0.3333 8.7 4ix7:B
29 2vr0:F 146 61 0.0699 0.1370 0.3279 9.1 2j7a:C, 2j7a:F, 2j7a:I, 2j7a:L, 2j7a:O, 2j7a:R, 2vr0:C
30 4nap:D 310 22 0.0385 0.0355 0.5000 9.5 4nap:A, 4nap:B, 4nap:C, 4pgn:A, 4pgn:B, 4pgn:C, 4pgn:D, 4pgp:A, 4pgp:B, 4pgp:C, 4pgp:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218