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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NKSEKARSMAAKVLNCGKNKIWLDPSGKEQINQVSTREQIRQLIDDNVIIKKLDKYNSKGRSRIYKEAVAKGRHMGLGKR
LGTANARLNKKTLWIKKIRVMRKELKDMKAEGKINAEEYQLFRKRAKGNLFKNRVTMKEHIAKKQAAELRIKELEEQAKA
LKMKK

The query sequence (length=165) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6rm3:LR0 165 165 1.0000 1.0000 1.0000 1.14e-116
2 7qep:M9 170 160 0.5576 0.5412 0.5750 5.91e-59
3 6zu5:LR0 161 155 0.4606 0.4720 0.4903 6.43e-47
4 4v6w:CR 203 156 0.4303 0.3498 0.4551 3.88e-37 6xu6:CR, 6xu7:CR, 6xu8:CR
5 6skf:BS 146 138 0.3879 0.4384 0.4638 7.18e-36 6skg:BS, 6th6:BS
6 3j79:T 181 156 0.4303 0.3923 0.4551 2.55e-35 3jbn:AT, 3jbo:AT, 3jbp:AT, 8tpu:AT, 5umd:T
7 9bh5:CR 194 152 0.4121 0.3505 0.4474 9.11e-35 9cai:CR
8 5xy3:R 162 154 0.4000 0.4074 0.4286 3.78e-33
9 4v6x:CR 189 152 0.4000 0.3492 0.4342 9.58e-33 7a01:32, 8a3d:L, 5aj0:AR, 8b5l:R, 8b6c:R, 9bdl:AL19, 9bdn:AL19, 9bdp:AL19, 8bf9:R, 7bhp:LR, 8bhf:E1, 8bpo:Q2, 8btk:BR, 7cpu:LR, 7cpv:LR, 4d5y:R, 4d67:R, 6d90:R, 6d9j:R, 9f1b:BR, 9f1c:BR, 9f1d:BR, 7f5s:LR, 8fl2:LD, 8fl3:LD, 8fl4:LD, 8fl6:LD, 8fl7:LD, 8fl9:LD, 8fla:LD, 8flb:LD, 8flc:LD, 8fld:LD, 8fle:LD, 8flf:LD, 9fpz:LR, 9fq0:LR, 6frk:R, 6ftg:R, 6fti:R, 6ftj:R, 8g5y:LR, 8g5z:LR, 8g60:LR, 8g61:LR, 8g6j:LR, 8glp:LR, 6gz3:AR, 6gz4:AR, 6gz5:AR, 6hcf:R3, 6hcj:R3, 6hcm:R3, 6hcq:R3, 8idt:a, 8idy:a, 8ie3:a, 8ifd:2L, 8ife:2L, 8ine:a, 8inf:a, 8ink:a, 6ip5:2L, 6ip6:2L, 6ip8:2L, 8ipd:a, 8ipx:a, 8ipy:a, 8ir1:a, 8ir3:a, 3j7o:R, 3j7p:R, 3j7q:R, 3j7r:R, 3j92:R, 3jag:R, 3jah:R, 3jai:R, 3jaj:R, 3jan:R, 8jdj:W, 8jdk:W, 8jdl:W, 8jdm:W, 8k2c:LR, 5lks:LR, 6lqm:a, 6lsr:a, 6lss:a, 7ls1:L2, 7ls2:L2, 6lu8:a, 5lzs:R, 5lzt:R, 5lzu:R, 5lzv:R, 5lzw:R, 5lzx:R, 5lzy:R, 5lzz:R, 7mdz:R, 6mtb:R, 6mtc:R, 6mtd:R, 6mte:R, 7nfx:R, 7nwg:R3, 7nwh:R, 7nwi:R, 7o7y:BR, 7o7z:BR, 7o80:BR, 7o81:BR, 7obr:R, 8ohd:LR, 8oj0:LR, 8oj5:LR, 8oj8:LR, 6ole:S, 6olf:S, 6olg:AR, 6oli:S, 6olz:AR, 6om0:S, 6om7:S, 8ony:LR, 7oya:R1, 7oyb:R1, 7oyc:R1, 7oyd:R, 8p2k:BR, 6p5i:AR, 6p5j:AR, 6p5k:AR, 6p5n:AR, 8q7z:BR, 8q87:BR, 8qfd:R, 7qgg:S, 8qoi:LR, 7qvp:LR, 7qvp:MR, 7qwq:R, 7qwr:R, 7qws:R, 6qzp:LR, 6r5q:R, 6r6g:R, 6r6p:R, 6r7q:R, 8rjb:R, 8rjc:R, 8rjd:R, 8scb:R, 6sgc:R2, 6swa:o, 6sxo:LR, 5t2c:L, 6t59:R3, 7tm3:R, 7toq:AL19, 7tor:AL19, 7tut:R, 7ucj:R, 7uck:R, 4ug0:LR, 4ujc:BR, 4ujd:AR, 4uje:CR, 6xa1:LR, 7xnx:LR, 7xny:LR, 8xsx:LR, 8xsy:LR, 8xsz:LR, 6y0g:LR, 8y0w:LR, 8y0x:LR, 6y2l:LR, 6y57:LR, 6y6x:LR, 8yoo:LR, 8yop:LR, 6z6l:LR, 6z6m:LR, 6z6n:LR, 7zjw:LU, 7zjx:LU, 6zm7:LR, 6zme:LR, 6zmi:LR, 6zmo:LR, 6zvk:32
10 4v4n:AQ 150 138 0.3758 0.4133 0.4493 1.00e-32 4v6u:BQ
11 8p5d:LR0 164 162 0.3636 0.3659 0.3704 2.81e-32 8p60:LR0, 8p60:KR0, 7qca:LR0
12 6zj3:Lf 170 133 0.3455 0.3353 0.4286 4.89e-32
13 8azw:H 182 156 0.4000 0.3626 0.4231 2.12e-31 8b2l:H3, 7qiw:T, 7qix:X, 7qiz:T
14 5xxb:Q 176 156 0.3939 0.3693 0.4167 6.69e-31
15 4v6i:BT 189 156 0.3758 0.3280 0.3974 1.43e-30 8aaf:E, 8agt:E, 8agu:E, 8agv:E, 8agw:E, 8agx:E, 8agz:E, 5apn:R, 5apo:R, 7azy:H, 7b7d:Ln, 8bip:LR, 8bjq:LR, 8bn3:M9, 8bqd:BF, 8bqx:BF, 7bt6:R, 7btb:R, 8ccs:D, 8cdl:D, 8cdr:D, 8ceh:D, 8cf5:D, 8cg8:D, 8cgn:D, 8civ:D, 8cku:D, 8cmj:D, 5dat:M9, 5dat:m9, 5dc3:M9, 5dc3:m9, 5dge:M9, 5dge:m9, 5dgf:M9, 5dgf:m9, 5dgv:M9, 5dgv:m9, 8eub:AR, 8evp:AR, 8evq:AR, 8evr:AR, 8evs:AR, 8evt:AR, 8ewb:AR, 8ewc:AR, 5fci:M9, 5fci:m9, 5fcj:M9, 5fcj:m9, 6ft6:R, 5gak:T, 6gq1:R, 6gqb:R, 6gqv:R, 5h4p:R, 6hd7:T, 8hfr:RP, 6hhq:z, 6hhq:CT, 5i4l:M9, 5i4l:m9, 6i7o:BF, 6i7o:YF, 3j6x:59, 3j6y:59, 3j77:69, 3j78:69, 3jct:R, 5jcs:R, 5juo:W, 5jup:W, 5jus:W, 5jut:W, 5juu:W, 8k2d:LR, 8k82:LR, 5lyb:M9, 5lyb:m9, 5m1j:R5, 6m62:R, 5mc6:BF, 5mei:z, 5mei:CT, 7mpi:AR, 7mpj:AR, 6n8j:R, 6n8k:R, 6n8l:R, 6n8m:e, 6n8n:e, 6n8o:e, 7n8b:AR, 5ndg:M9, 5ndg:m9, 5ndv:M9, 5ndv:m9, 5ndw:M9, 5ndw:m9, 7nrc:LT, 7nrd:LT, 5obm:M9, 5obm:m9, 7of1:R, 7oh3:R, 7ohq:R, 6oig:R, 5on6:z, 5on6:CT, 7osa:eL19, 7osm:eL19, 8p8m:QQ, 8p8n:QQ, 8p8u:QQ, 8pfr:QQ, 6q8y:BF, 6qik:R, 6qt0:R, 6qtz:R, 6r84:T, 6r86:T, 6r87:T, 6ri5:R, 7rr5:LR, 6rzz:R, 6s05:R, 6s47:AT, 6snt:x, 6sv4:BF, 6sv4:YF, 6sv4:ZF, 6t4q:LR, 5t62:e, 5t6r:e, 6t7i:LR, 6t7t:LR, 6t83:Ry, 6t83:C, 5tbw:z, 5tbw:CT, 6tb3:BF, 5tga:M9, 5tga:m9, 5tgm:M9, 5tgm:m9, 6tnu:BF, 7too:AL19, 7top:AL19, 7u0h:R, 4u3m:M9, 4u3m:m9, 4u3n:M9, 4u3n:m9, 4u3u:M9, 4u3u:m9, 4u4n:M9, 4u4n:m9, 4u4o:M9, 4u4o:m9, 4u4q:M9, 4u4q:m9, 4u4r:M9, 4u4r:m9, 4u4u:M9, 4u4u:m9, 4u4y:M9, 4u4y:m9, 4u4z:M9, 4u4z:m9, 4u50:M9, 4u50:m9, 4u51:M9, 4u51:m9, 4u52:M9, 4u52:m9, 4u53:M9, 4u53:m9, 4u55:M9, 4u55:m9, 4u56:M9, 4u56:m9, 4u6f:M9, 4u6f:m9, 7ug6:R, 7uoo:R, 7uqb:R, 7uqz:R, 7v08:R, 4v4b:BP, 4v7f:R, 4v7r:BS, 4v7r:DS, 4v88:BR, 4v88:DR, 4v8t:R, 4v8y:BR, 4v8z:BR, 4v91:R, 6woo:R, 2ww9:J, 2wwa:J, 2wwb:J, 6xiq:R, 6xir:R, 8y0u:LR, 6ylg:R, 6ylh:R, 6ylx:R, 6yly:R, 7z34:R, 6z6j:LR, 6z6k:LR, 7zpq:BQ, 7zrs:BQ, 7zs5:BS, 7zuw:BQ, 7zux:EQ, 7zw0:LU
16 5it7:RR 188 156 0.3879 0.3404 0.4103 2.04e-30 6uz7:AR
17 4v8p:BO 184 156 0.3697 0.3315 0.3910 2.30e-30 4v8p:EO, 4v8p:GO
18 8br8:LS 192 133 0.3515 0.3021 0.4361 2.90e-30 8brm:LS, 8bsi:LS, 8bsj:LS, 8btd:LS, 8btr:LS, 8fru:R, 7pwg:R, 7pwo:R2
19 4v3p:LT 189 152 0.3879 0.3386 0.4211 2.95e-30 8ip8:LA, 8ipa:LA, 8ipb:LA, 8jiv:CR, 4v7e:CR
20 8c3a:z 179 149 0.3758 0.3464 0.4161 4.12e-30 8c3a:BM, 8cq7:z, 8cq7:BM, 8cqw:z, 8cqw:BM, 8cre:z, 8cre:BM, 8oeq:z, 8oeq:BM, 7pzy:z, 7q08:z, 7q0f:z, 7q0p:z, 7q0r:z, 8q5i:z
21 4v8p:CO 175 137 0.3455 0.3257 0.4161 3.58e-29
22 7r81:T1 191 152 0.3697 0.3194 0.4013 1.14e-28 7olc:LR, 7old:LR, 8onz:LR, 8oo0:LR, 8pv1:LR, 8pv2:LR, 8pv3:LR, 8pv4:LR, 8pv5:LR, 8pv6:LR, 8pv7:LR, 8pv8:LR, 8pvk:LR, 8pvl:LR, 7z3n:LR, 7z3o:LR
23 8rxh:LQ 201 152 0.3515 0.2886 0.3816 9.03e-28 8a3w:Q, 8a98:Q, 6az3:Q, 3jcs:Q, 8ovj:Q, 8rxx:LQ, 5t2a:R
24 4v7h:BP 176 133 0.3273 0.3068 0.4060 2.83e-27
25 4v8m:BT 199 156 0.3455 0.2864 0.3654 3.58e-27 8ova:BT, 8ove:BT, 5t5h:T
26 8eui:R 149 138 0.3273 0.3624 0.3913 3.16e-26 8etg:R, 8etj:R, 8eug:R
27 6w6l:S 156 152 0.3576 0.3782 0.3882 7.66e-26 8fky:LD, 8fkz:LD, 7ow7:L
28 4v9f:P 144 133 0.2848 0.3264 0.3534 9.53e-25 3cc2:P, 3cc4:P, 3cc7:P, 3cce:P, 3ccj:P, 3ccl:P, 3ccm:P, 3ccq:P, 3ccr:P, 3ccs:P, 3ccu:P, 3ccv:P, 3cd6:P, 3cma:P, 3cme:P, 3cpw:O, 3cxc:O, 1ffk:M, 3g4s:P, 3g6e:P, 3g71:P, 3i55:P, 3i56:P, 1jj2:O, 1k73:Q, 1k8a:Q, 1k9m:Q, 1kc8:Q, 1kd1:Q, 1kqs:O, 1m1k:Q, 1m90:Q, 1n8r:Q, 1nji:Q, 2otj:P, 2otl:P, 3ow2:O, 1q7y:Q, 1q81:Q, 1q82:Q, 1q86:Q, 2qa4:P, 2qex:P, 1qvf:O, 1qvg:O, 1s72:P, 1vq4:P, 1vq5:P, 1vq6:P, 1vq7:P, 1vq8:P, 1vq9:P, 1vqk:P, 1vql:P, 1vqm:P, 1vqn:P, 1vqo:P, 1vqp:P, 1w2b:O, 1yhq:P, 1yi2:P, 1yij:P, 1yit:P, 1yj9:P, 1yjn:P, 1yjw:P
29 4v5z:Bp 159 121 0.2909 0.3019 0.3967 1.58e-17
30 8i9z:LR 148 152 0.2788 0.3108 0.3026 1.36e-16 8i9x:LR, 8i9y:LR, 8ia0:LR
31 7nac:R 134 152 0.2970 0.3657 0.3224 3.74e-16 6elz:R, 6em5:R, 7nad:R, 7naf:R, 7ohr:R, 7r72:R, 7r7a:R, 8v87:R
32 8hku:L19E 144 136 0.2788 0.3194 0.3382 9.68e-16 8hkv:L19E, 8hky:L19E, 8hkz:L19E, 8hl1:L19E, 8hl2:L19E, 8hl3:L19E, 8hl4:L19E, 8hl5:L19E
33 8etc:R 124 133 0.2424 0.3226 0.3008 2.74e-13 8esq:R, 8esr:R
34 7ohv:R 89 44 0.1152 0.2135 0.4318 3.39e-07
35 8qv2:Sn 64 36 0.0788 0.2031 0.3611 0.83
36 1v1f:A 188 27 0.0788 0.0691 0.4815 3.4 2ehb:A, 1v1g:A
37 7k5b:B 4524 33 0.0788 0.0029 0.3939 4.7 8bx8:B, 7k58:B, 7kek:B
38 5c22:B 267 84 0.1515 0.0936 0.2976 5.7
39 2b7r:A 568 88 0.1515 0.0440 0.2841 7.0 2b7s:A, 1e39:A, 1jrx:A, 1jrx:B, 1jry:A, 1jry:B, 1jrz:A, 1jrz:B, 1kss:A, 1ksu:A, 1ksu:B, 1lj1:A, 1lj1:B, 1m64:A, 1m64:B, 1p2e:A, 1p2h:A, 1q9i:A, 1qjd:A, 1y0p:A
40 6clv:C 257 20 0.0606 0.0389 0.5000 8.9 1ad4:A, 6clv:A, 6clv:B
41 7uof:A 423 25 0.0848 0.0331 0.5600 9.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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