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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGY
NCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSD
VSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVK
IGKLNLVDLAGSENNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEY
AHRAKNILNK

The query sequence (length=330) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5zo8:A 331 330 0.9818 0.9789 0.9818 0.0 4a51:G, 4a51:E, 4a51:F, 4a5y:B, 4ap0:D, 4ap0:B, 2gm1:B, 2gm1:D, 6hky:C, 6trl:A, 8yhh:B, 5zo8:B, 5zo9:A, 5zo9:B
2 4aqv:C 361 345 0.9848 0.9003 0.9420 0.0 4a28:A, 4a50:A, 4a5y:A, 4a5y:C, 4as7:A, 4b7b:A, 4bbg:A, 4bxn:A, 4bxn:B, 3cjo:A, 3cjo:B, 4ck6:C, 4ck7:C, 2fky:A, 2fky:B, 2fl2:A, 2fl2:B, 2fl6:A, 2fl6:B, 2fme:B, 2g1q:A, 2g1q:B, 6g6z:A, 6hkx:B, 3hqd:A, 3hqd:B, 2ieh:A, 2ieh:B, 1ii6:A, 1ii6:B, 3k3b:A, 3k3b:B, 3k5e:A, 3ken:A, 3l9h:A, 3l9h:B, 2pg2:A, 2pg2:B, 1q0b:A, 1q0b:B, 2q2y:A, 2q2y:B, 2q2z:A, 2q2z:B, 6ta4:K, 6tle:A, 6tle:B, 6trl:B, 2uyi:A, 2uyi:B, 2uym:A, 2uym:B, 2wog:A, 2wog:B, 2wog:C, 2x2r:A, 2x2r:C, 2x7c:A, 2x7c:B, 2x7d:A, 2x7d:B, 2x7e:A, 2x7e:B, 1x88:A, 1x88:B, 2xae:C, 1yrs:A, 1yrs:B, 4zca:A, 4zhi:A, 4zhi:B, 5zo7:A, 5zo7:B
3 6ta3:K 334 345 0.9364 0.9251 0.8957 0.0 4a1z:A, 4a1z:B, 4a28:B, 4a51:A, 4a51:B, 4a51:C, 4a51:D, 4ap0:A, 2fme:A, 6g6y:A, 2gm1:A, 2gm1:E, 6hkx:A, 6hky:A, 6hky:B, 3k5e:B, 6tiw:K, 2x2r:B, 2xae:A, 2xae:B, 6y1i:A, 6y1i:B, 6y1i:C, 8yhh:A, 3zcw:A, 4zca:B
4 4ap0:C 311 329 0.9303 0.9871 0.9331 0.0
5 3wpn:A 309 330 0.9061 0.9676 0.9061 0.0
6 7lxr:B 344 340 0.6030 0.5785 0.5853 1.47e-135 7lxr:A, 6vpo:C, 2wbe:C
7 5mm7:K 397 378 0.5515 0.4584 0.4815 1.19e-100 5mm4:K
8 5m5i:C 369 361 0.5061 0.4526 0.4626 2.37e-95 5m5l:C, 5m5m:C, 5m5n:C, 5m5o:C
9 6s8m:K 344 349 0.4909 0.4709 0.4642 3.57e-95
10 3b6u:B 343 334 0.4636 0.4461 0.4581 2.01e-93 3b6u:A
11 7nba:K 331 350 0.4636 0.4622 0.4371 1.55e-88
12 3b6v:A 306 330 0.4333 0.4673 0.4333 1.22e-80 3b6v:B
13 7a5e:A 338 348 0.4545 0.4438 0.4310 1.84e-79 7a5e:B
14 3zfd:A 340 347 0.4364 0.4235 0.4150 1.37e-77 3zfc:A
15 1goj:A 354 349 0.4515 0.4209 0.4269 2.78e-77
16 2vvg:B 309 332 0.4273 0.4563 0.4247 7.28e-77 2vvg:A
17 7a3z:A 307 332 0.4333 0.4658 0.4307 9.22e-75
18 2y65:C 343 333 0.4333 0.4169 0.4294 3.03e-70 2y5w:A, 2y5w:B, 2y65:D, 2y65:B, 2y65:A
19 1mkj:A 336 335 0.4455 0.4375 0.4388 6.22e-69 4atx:C, 1bg2:A, 4hna:K, 8ixa:Y, 8ixa:S, 8ixa:T, 8ixa:U, 8ixa:V, 8ixa:W, 8ixa:X, 8ixa:Z, 8ixa:a, 8ixb:l, 8ixb:g, 8ixb:k, 8ixb:m, 8ixd:Y, 8ixd:S, 8ixd:T, 8ixd:U, 8ixd:V, 8ixd:W, 8ixd:X, 8ixd:Z, 8ixd:a, 8ixe:l, 8ixe:h, 8ixe:p, 8ixe:q, 8ixf:Y, 8ixf:S, 8ixf:T, 8ixf:U, 8ixf:V, 8ixf:W, 8ixf:X, 8ixf:Z, 8ixf:a, 8ixg:l, 8ixg:h, 8ixg:p, 8ixg:q, 3j8y:K, 2p4n:K
20 6zpi:C 332 306 0.4121 0.4096 0.4444 1.33e-68 4bn2:A, 4bn2:B, 6zph:B
21 4bn2:C 311 335 0.4424 0.4695 0.4358 4.40e-68
22 7eo9:A 351 341 0.3970 0.3732 0.3842 6.93e-68 7eob:A, 2hxf:C, 1i6i:A, 1ia0:K, 1vfv:A, 1vfw:A, 1vfx:A, 2zfi:A, 2zfj:A, 2zfk:A, 2zfl:A, 2zfm:A
23 7z2b:K 308 340 0.4000 0.4286 0.3882 3.20e-67
24 5hnw:K 329 339 0.4394 0.4407 0.4277 4.00e-67 5hle:A, 5hny:K, 3x2t:B
25 4uy0:C 333 351 0.4515 0.4474 0.4245 1.69e-66
26 3x2t:A 311 333 0.4424 0.4695 0.4384 6.42e-66 2kin:A, 3kin:A, 3kin:C
27 7rx0:C 328 344 0.4091 0.4116 0.3924 2.70e-65 6mlq:C, 6mlr:C
28 3lre:B 300 331 0.3909 0.4300 0.3897 3.42e-65 3lre:A, 7rsi:C
29 5ocu:K 333 347 0.3970 0.3934 0.3775 2.31e-64 5ogc:K
30 6wwk:K 368 362 0.4152 0.3723 0.3785 7.28e-63 7lvq:K, 7lvr:K, 6wwf:K, 6wwg:K, 6wwg:N, 6wwh:K, 6wwh:N, 6wwj:K, 6wwk:N, 6wwl:K, 6wwl:N, 6wwm:K, 6wwn:K, 6wwo:K, 6wwq:K, 6wwr:K, 6wws:K, 6wwu:K, 6wwv:K
31 8uto:N 389 368 0.4000 0.3393 0.3587 1.42e-62 2hxh:C, 1i5s:A, 8utn:K, 8utn:N, 8uto:K, 8utp:K, 8utp:N, 8utq:K, 8utr:K, 8utt:K, 8utt:N, 8utu:K, 8utv:K, 8uty:K, 8uty:N, 4uxp:C, 1vfz:A
32 6a20:A 395 342 0.4061 0.3392 0.3918 2.36e-62 6a1z:A, 7d8v:A, 3gbj:B, 5zbr:B, 5zbr:A, 5zbr:C, 5zbs:B, 5zbs:A
33 7tr1:K 346 354 0.4182 0.3988 0.3898 3.52e-61 7lff:A, 7lff:B
34 2xt3:A 300 330 0.3818 0.4200 0.3818 6.79e-60 4a14:A
35 1t5c:A 322 339 0.4061 0.4161 0.3953 2.67e-59 8hfh:A, 6m4i:A, 6m4i:B, 1t5c:B
36 7rs5:K 346 359 0.3909 0.3728 0.3593 4.51e-59 7rs5:a, 7rs5:b, 7rs5:c, 7rs5:d, 7rs5:e, 7rs5:f, 7rs5:g, 7rs5:h, 7rs6:K, 7rs6:a, 7rs6:b, 7rs6:c, 7rs6:d, 7rs6:e, 7rs6:f, 7rs6:g, 7rs6:h
37 2owm:A 328 328 0.3970 0.3994 0.3994 5.62e-59 2owm:B, 2owm:C, 2owm:D
38 7x4n:E 332 350 0.4000 0.3976 0.3771 2.87e-58
39 5gsz:A 306 336 0.3788 0.4085 0.3720 9.47e-58
40 7wrg:A 812 359 0.3939 0.1601 0.3621 1.67e-57
41 7tr3:K 418 302 0.3727 0.2943 0.4073 2.66e-57 7tqx:K, 7tqy:K, 7tr0:K
42 5zbs:C 323 345 0.4030 0.4118 0.3855 3.46e-57 3gbj:A, 3gbj:C
43 7n61:0X 420 348 0.3697 0.2905 0.3506 1.90e-56 7n61:0Y, 7n61:0Z, 7n61:1A
44 7wrg:B 783 355 0.3909 0.1648 0.3634 2.52e-55
45 3cob:A 355 346 0.3697 0.3437 0.3526 4.53e-55 3cob:C, 1sdm:A
46 5wde:A 320 341 0.3788 0.3906 0.3666 1.01e-54
47 1cz7:D 365 325 0.3394 0.3068 0.3446 2.41e-54 1cz7:A, 1cz7:B, 1cz7:C, 3l1c:A, 1n6m:A, 2ncd:A, 3u06:A, 5w3d:A
48 4ozq:B 687 344 0.3909 0.1878 0.3750 1.51e-53 4ozq:A
49 3cnz:A 333 331 0.3576 0.3544 0.3565 2.15e-50 3cnz:B
50 6nje:A 297 291 0.3424 0.3805 0.3883 9.18e-49
51 3nwn:A 308 292 0.3242 0.3474 0.3664 1.17e-48
52 5mio:C 477 352 0.3727 0.2579 0.3494 4.94e-47 1v8j:A, 5xjb:A
53 3h4s:A 359 349 0.3636 0.3343 0.3438 1.08e-46 4frz:A, 4frz:B
54 5nd4:C 337 304 0.3121 0.3056 0.3388 2.65e-46
55 3dcb:A 299 286 0.3061 0.3378 0.3531 8.78e-46 3dc4:A, 3dco:N, 3pxn:A
56 6b0l:K 368 303 0.3182 0.2853 0.3465 1.13e-43 6b0c:K
57 5wdh:A 296 327 0.3455 0.3851 0.3486 1.82e-43
58 4etp:A 379 346 0.3515 0.3061 0.3353 3.35e-43 1f9t:A, 1f9u:A, 1f9v:A, 3kar:A
59 3u06:B 344 283 0.2879 0.2762 0.3357 6.24e-43 3l1c:B, 1n6m:B
60 4gkr:B 307 286 0.3121 0.3355 0.3601 3.26e-42 4gkr:A
61 6bbn:E 378 345 0.3455 0.3016 0.3304 4.55e-42 2gry:A
62 5nd7:C 300 337 0.3182 0.3500 0.3116 6.41e-42
63 5nd2:C 280 325 0.3121 0.3679 0.3169 1.80e-40
64 4ubf:A 309 330 0.3485 0.3722 0.3485 5.30e-40
65 5xja:A 337 346 0.3515 0.3442 0.3353 1.01e-38 3edl:D, 2heh:A, 4ubf:B, 4ubf:C, 4ubf:D, 1v8k:A, 5xja:B, 5xjb:B, 4y05:A
66 4h1g:A 670 342 0.3455 0.1701 0.3333 1.17e-38
67 3t0q:A 304 352 0.3606 0.3914 0.3381 1.03e-37
68 1f9w:A 300 335 0.3364 0.3700 0.3313 3.84e-34 1f9w:B
69 8bjs:A 343 378 0.3121 0.3003 0.2725 1.05e-33
70 5w3d:B 313 323 0.3091 0.3259 0.3158 1.28e-33
71 3dev:A 316 98 0.0636 0.0665 0.2143 1.4 3dev:B
72 8bjz:L 213 38 0.0455 0.0704 0.3947 1.9 8bjz:B, 8bso:L, 8bso:D
73 8ad2:A 165 42 0.0455 0.0909 0.3571 3.3 8ad2:B, 8ad2:C, 8ad2:D, 8ad2:F, 8ad2:G, 8qmg:A, 8qmg:B, 8qmg:C, 8qmg:D, 8qmg:F, 8qmg:G
74 8dmf:A 718 83 0.0606 0.0279 0.2410 7.1 7uvp:A
75 1eye:A 256 62 0.0515 0.0664 0.2742 7.2
76 2wzm:A 274 71 0.0606 0.0730 0.2817 8.0 2wzm:B
77 7cqt:A 450 217 0.1424 0.1044 0.2166 8.8 7cqt:B, 7cqt:C, 2fa0:A, 2fa3:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218