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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NHSEQTLYQLMSERLALMPEVAKYKWHHNLPIEDLAREAMVLERTVSRTTVLDPIHTKTFFGLQMTAAKAIQANVFQSLT
NTDVVASDVRSLNDDLRPKLTLLGDQIIEQLLISYQNGTPLNRAHFDAHFAHFELNPQIKDGLFKSLELVLTPDPRDTLA
RLEKDKTLRVGVTLDYEPFSYQDNEGNRAGIDIELATALAKEFGYRIVWVKTSWPTLMADAEDNLFDIALSGISITAQRQ
HRMMFSAPYHTGGKTAIGRCSSVDELNTLALIDRAETRIIVNPGGTNERFVRSALTNASIRIHPDNRTIFNELVSGTADA
MFTDSIEAQLQATKHPSLCVLLDQPLTFQQKGILLQPDPELKKRIDTWLLDYLSSHDVSALFSKHGVDPD

The query sequence (length=390) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8pnj:A 390 390 1.0000 1.0000 1.0000 0.0
2 8pnh:A 386 214 0.2692 0.2720 0.4907 1.26e-59
3 8pnh:A 386 116 0.1000 0.1010 0.3362 5.05e-07
4 5t0w:A 229 228 0.2077 0.3537 0.3553 1.74e-42 5t0w:B, 5t0w:C, 5t0w:D
5 3k4u:E 234 227 0.1641 0.2735 0.2819 4.73e-21 3k4u:A, 3k4u:B, 3k4u:C, 3k4u:D, 3k4u:F
6 4zv1:A 226 207 0.1462 0.2522 0.2754 2.76e-20 4zv2:A
7 4i62:A 237 210 0.1487 0.2447 0.2762 3.26e-17
8 6svf:A 229 209 0.1513 0.2576 0.2823 1.31e-15 6ggv:A, 6ggv:B, 4psh:A, 4psh:B, 6q3u:A
9 5lom:B 250 182 0.1205 0.1880 0.2582 3.24e-14 6hqh:A, 5l9o:A, 5l9o:B, 5lom:A
10 5kkw:A 237 177 0.1154 0.1899 0.2542 5.14e-14
11 4h5f:A 240 176 0.1256 0.2042 0.2784 6.06e-13 4h5f:B, 4h5f:C, 4h5f:D, 4h5g:A, 4h5g:B
12 1xt8:B 251 221 0.1462 0.2271 0.2579 1.25e-12 1xt8:A
13 7a99:B 130 83 0.0718 0.2154 0.3373 4.31e-12 7a99:A, 6gpc:A, 6gpc:B
14 2q2a:A 241 228 0.1436 0.2324 0.2456 6.38e-11 2pvu:A, 2q2a:B, 2q2a:C, 2q2a:D, 2q2c:A, 2q2c:B, 2q2c:C, 2q2c:D
15 2yln:A 240 96 0.0744 0.1208 0.3021 7.67e-11
16 1laf:E 238 174 0.1077 0.1765 0.2414 8.07e-11 6ft2:A, 1lag:E, 1lah:E, 1lst:A, 6mku:E, 6mkw:A, 6ml9:E, 6mla:E, 6mle:E, 6mlg:E, 6mli:E, 6mlj:A, 6mlj:B, 6mln:E, 6mlo:E, 6mlp:E, 5owf:A
17 4g4p:A 235 211 0.1282 0.2128 0.2370 1.31e-09
18 1hsl:A 238 174 0.1154 0.1891 0.2586 1.42e-09 1hsl:B
19 4ohn:A 246 106 0.0692 0.1098 0.2547 4.86e-09
20 2y7i:A 228 87 0.0641 0.1096 0.2874 6.05e-09 2y7i:B
21 3vvd:A 241 102 0.0615 0.0996 0.2353 1.82e-08 3vv5:A, 3vv5:B, 3vvd:B, 3vve:A, 3vve:B, 3vvf:A, 3vvf:B
22 2yjp:A 247 191 0.1205 0.1903 0.2461 4.39e-08 2yjp:B, 2yjp:C
23 8hqr:A 267 128 0.0897 0.1311 0.2734 5.30e-08 8hqr:B
24 3i6v:A 218 204 0.1256 0.2248 0.2402 1.57e-07
25 4f3s:A 231 214 0.1179 0.1991 0.2150 2.84e-07 4dz1:A
26 3qax:B 235 88 0.0667 0.1106 0.2955 3.72e-07 3n26:A, 3qax:A
27 4ymx:A 224 181 0.1026 0.1786 0.2210 4.43e-07 4ymx:B
28 8gtu:A 236 84 0.0718 0.1186 0.3333 6.35e-07 6a80:A, 6a80:B, 6a8s:A, 6a8s:B, 6aal:A, 8gtu:B, 8gu1:A, 8gu1:B
29 5org:A 257 89 0.0590 0.0895 0.2584 7.61e-07 5org:B
30 4kqp:A 230 213 0.1051 0.1783 0.1925 7.72e-07
31 3tql:A 225 162 0.1000 0.1733 0.2407 2.64e-06
32 5ovz:A 259 84 0.0513 0.0772 0.2381 1.03e-05 5ito:A, 5ito:B, 5itp:A, 5itp:B, 5ot8:A, 5ot8:B, 5ot9:A, 5ot9:B, 5ota:A, 5ota:B, 5otc:A, 5otc:B, 5ovz:B, 4pow:A, 4pow:B, 4pp0:A, 4pp0:B
33 6det:A 243 221 0.1256 0.2016 0.2217 1.26e-05
34 8vi8:A 227 162 0.0897 0.1542 0.2160 3.29e-05 8eyz:A, 8eyz:B, 8eyz:C, 8eyz:D, 8eyz:E, 8eyz:F, 8eyz:G, 8eyz:H, 8eyz:I, 8eyz:J, 8eyz:L, 8eyz:K, 8hnj:A, 8hnj:B, 8hnj:C, 8hnj:D, 8hnj:E, 8hnj:F, 8vi8:B, 8vi8:C, 8vi8:D, 8vi8:E, 8vi8:F, 1wdn:A
35 4zef:A 239 156 0.0923 0.1506 0.2308 3.89e-05
36 4eq9:A 240 72 0.0538 0.0875 0.2917 4.29e-05
37 5eyf:B 243 178 0.1154 0.1852 0.2528 6.18e-05 5eyf:A
38 2pyy:B 217 84 0.0641 0.1152 0.2976 3.17e-04 2pyy:A, 2pyy:C
39 8ovo:A 503 251 0.1359 0.1054 0.2112 4.00e-04 8ovo:B, 8ovp:A, 8ovp:B, 2vha:A, 2vha:B
40 6fxg:B 226 85 0.0513 0.0885 0.2353 4.32e-04 8b5d:A, 8b5d:B, 8b5e:A, 8b5e:B, 6fxg:A, 6fxg:C
41 2ao2:A 165 72 0.0615 0.1455 0.3333 0.001 2ao2:B, 2ao2:C, 2fp2:B
42 2ia4:B 278 256 0.1333 0.1871 0.2031 0.004 2ia4:A
43 5ikb:A 249 105 0.0769 0.1205 0.2857 0.010
44 7yfg:B 652 185 0.1103 0.0660 0.2324 0.025 8e94:B, 7yfg:D, 7yfh:B, 7yfh:D
45 3oek:A 270 181 0.1026 0.1481 0.2210 0.076 4jwy:A, 3oel:A, 3oem:A
46 5dt6:A 266 64 0.0462 0.0677 0.2812 0.15 5ict:A
47 1ecm:B 95 80 0.0615 0.2526 0.3000 0.19 1ecm:A
48 4io7:B 246 178 0.1077 0.1707 0.2360 0.20 4io2:A, 4io2:B, 4io3:A, 4io3:B, 4io4:A, 4io4:B, 4io5:A, 4io5:B, 4io6:A, 4io6:B, 4io7:A
49 7qep:O5 121 55 0.0462 0.1488 0.3273 0.48
50 8bn5:B 267 72 0.0513 0.0749 0.2778 1.0 8blj:A, 8blj:B, 8blj:C, 8blj:D, 8blj:E, 8blj:F, 8bn2:A, 8bn2:B, 8bn5:A
51 4gvo:A 236 82 0.0436 0.0720 0.2073 1.5 4gvo:B
52 7aju:UL 779 78 0.0538 0.0270 0.2692 1.5 5wyj:BB, 5wyk:BB, 6zqd:UL, 6zqe:UL, 6zqf:UL
53 7d5s:B2 851 78 0.0538 0.0247 0.2692 1.6 7ajt:UL, 7d4i:B2, 7d5t:B2, 7d63:B2, 6ke6:B2, 6lqp:B2, 6lqq:B2, 6lqr:B2, 6lqs:B2, 6lqt:B2, 6lqu:B2, 6lqv:B2, 7suk:LQ, 5wlc:LQ, 6zqa:UL, 6zqb:UL, 6zqc:UL
54 6c66:A 511 105 0.0641 0.0489 0.2381 2.2 5u07:C, 5u0a:C
55 3oen:A 250 177 0.0949 0.1480 0.2090 3.7
56 6xz0:A 250 45 0.0385 0.0600 0.3333 3.9 6xxq:A, 6xxq:B
57 7moq:C 4159 72 0.0333 0.0031 0.1806 6.2 6zyy:C
58 8oiv:A 293 106 0.0744 0.0990 0.2736 6.7 1av6:A, 8b07:A, 8b07:B, 1b42:A, 1bky:A, 8ceq:A, 8ceq:B, 8cer:A, 8cer:B, 8ces:A, 8ces:B, 8cet:A, 8cet:B, 8cev:A, 8cev:B, 8cgb:A, 4dcg:A, 1eam:A, 1eqa:A, 3er8:A, 3er8:B, 1jsz:A, 1jte:A, 1jtf:A, 3mag:A, 3mct:A, 8oiv:B, 1p39:A, 1v39:A, 1vp3:A, 1vp9:A, 1vpt:A, 2vp3:A
59 2gtv:X 104 36 0.0333 0.1250 0.3611 7.0
60 7ojj:L 1785 106 0.0718 0.0157 0.2642 7.1
61 6zyw:C 4433 72 0.0333 0.0029 0.1806 7.2
62 8bwy:C 4264 72 0.0333 0.0030 0.1806 7.4
63 5hg1:A 867 39 0.0333 0.0150 0.3333 7.6
64 4e54:B 402 89 0.0436 0.0423 0.1910 9.5 4e5z:B, 6r8y:L, 6r8z:L, 6r90:L, 6r91:L, 6r92:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218