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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NHLGKTEVFLNRFALRPLNPEELRPWRLEVVLDPPPGREEVYPLLAQVARRAGGVTVRMGDGLASWSPPEVLVLEGTLAR
MGQTYAYRLYPKGRRPLDPKDPGERSVLSALARRLLQERLRRLEGVWVEGLAVYRREHARGPGWRVLGGAVLDLWVSDSG
AFLLEVDPAYRILCEMSLEAWLAQGHPLPKRVRNAYDRRTWELLRLGEEDPKELPLPGGLSLLDYHASKGRLQGREGGRV
AWVADPKDPRKPIPHLTGLLVPVLTLEDLHEEEGSLALSLPWEERRRRTREIASWIGRRLGLGTPEAVRAQAYRLSIPKL
MGRRAVSKPADALRVGFYRAQETALALLRLDGAQGWPEFLRRALLRAFGASGASLRLHTLHAHPSQGLAFREALRKAKEE
GVQAVLVLTPPMAWEDRNRLKALLLREGLPSQILNVPLREEERHRWENALLGLLAKAGLQVVALSGAYPAELAVGFDAGG
RESFRFGGAACAVGGDGGHLLWTLPEAQAGERIPQEVVWDLLEETLWAFRRKAGRLPSRVLLLRNGRVPQDEFALALEAL
AREGIAYDLVSVRKSGGGRVYPVQGRLADGLYVPLEDKTFLLLTVHRDFRGTPRPLKLVHEAGDTPLEALAHQIFHLTRL
YPASGFAFPRLPAPLHLADRLVKEVGRLGIRHLKEVDREKLFFV

The query sequence (length=684) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5xow:A 684 684 1.0000 1.0000 1.0000 0.0 3dlb:A, 3dlb:B, 3dlh:A, 3dlh:B, 3f73:A, 3f73:B, 5gq9:B, 3hjf:A, 3hk2:A, 3hk2:B, 3ho1:A, 4kpy:A, 4kpy:B, 4n41:A, 4n41:B, 4n47:A, 4n76:B, 4nca:A, 4nca:B, 4ncb:A, 4ncb:B, 5xp8:A, 5xpa:A, 5xpg:A, 5xq2:A, 5xq2:B
2 3hvr:A 660 683 0.9635 0.9985 0.9649 0.0 3hm9:A, 3hvr:B
3 4n76:A 641 683 0.9357 0.9984 0.9370 0.0 5gq9:A, 3hxm:A
4 5xou:B 574 409 0.5965 0.7108 0.9976 0.0 5xou:A
5 5xou:B 574 172 0.2442 0.2909 0.9709 4.11e-92 5xou:A
6 6qzk:A 746 512 0.1667 0.1528 0.2227 1.17e-20
7 1yvu:A 682 268 0.1053 0.1056 0.2687 2.21e-12
8 2f8s:A 704 272 0.1067 0.1037 0.2684 2.24e-12 2f8t:A
9 8jpx:B 770 297 0.1009 0.0896 0.2323 1.68e-10 8jpx:A
10 1z26:A 716 294 0.0994 0.0950 0.2313 1.40e-09 1z25:A
11 5g5s:A 692 247 0.0789 0.0780 0.2186 6.37e-09 5g5t:A
12 8wd8:A 750 298 0.1023 0.0933 0.2349 2.93e-07 8jsi:A, 8jsi:B, 8wd8:B
13 5ux0:D 639 201 0.0687 0.0736 0.2338 1.11e-06 5i4a:A, 5i4a:C, 5ux0:A
14 6uak:A 297 40 0.0205 0.0471 0.3500 1.2
15 4twr:A 325 58 0.0351 0.0738 0.4138 1.2 4wok:A
16 1pv8:A 276 83 0.0424 0.1051 0.3494 1.3
17 6yw5:UU 224 80 0.0395 0.1205 0.3375 1.8 6ywe:UU, 6ywx:UU, 6ywy:UU
18 8in8:C 470 151 0.0482 0.0702 0.2185 4.0 8jl0:B, 8k87:A, 8k87:F, 8k88:A
19 3noi:B 120 95 0.0380 0.2167 0.2737 5.6
20 7p2t:D 374 35 0.0190 0.0348 0.3714 8.2
21 3da1:A 496 79 0.0365 0.0504 0.3165 8.3
22 7r8y:A 228 63 0.0322 0.0965 0.3492 8.7
23 6bhq:A 208 40 0.0161 0.0529 0.2750 8.8 6bhq:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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