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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NGAQGTKFRISLGLPVGAIMNCADNSGARNLYIIAVKGSGSRLNRLPAASLGDMVMATVKKGKPELRKKVMPAIVVRQAK
SWRRRDGVFLYFEDNAGVIANPKGEMKGSAITGPVGKECADLWPRVASNSGVVV

The query sequence (length=134) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8aaf:I 136 134 1.0000 0.9853 1.0000 3.13e-95 8agt:I, 8agu:I, 8agv:I, 8agw:I, 8agx:I, 8agz:I, 5apn:V, 5apo:V, 7azy:c, 7b7d:Lr, 8bip:LV, 8bjq:LV, 8bn3:N3, 8bqd:AB, 8bqx:AB, 7bt6:V, 7btb:V, 6c0f:V, 8ccs:H, 8cdl:H, 8cdr:H, 8ceh:H, 8cf5:H, 8cg8:H, 8cgn:H, 8civ:H, 8cku:H, 8cmj:H, 5dat:N3, 5dat:n3, 5dc3:N3, 5dc3:n3, 5dge:N3, 5dge:n3, 5dgf:N3, 5dgf:n3, 5dgv:N3, 5dgv:n3, 6elz:V, 6em1:V, 6em5:V, 8eub:AV, 8evp:AV, 8evq:AV, 8evr:AV, 8evs:AV, 8evt:AV, 8ewb:AV, 8ewc:AV, 5fci:N3, 5fci:n3, 5fcj:N3, 5fcj:n3, 6ft6:V, 5gak:X, 6gq1:V, 6gqb:V, 6gqv:V, 5h4p:V, 6hd7:X, 8hfr:V5, 6hhq:6, 6hhq:CX, 5i4l:N3, 5i4l:n3, 6i7o:AB, 6i7o:XB, 5it7:VV, 3j16:I, 3j6x:63, 3j6y:63, 3j77:73, 3j78:73, 3jct:V, 5jcs:V, 5juo:AA, 5jup:AA, 5jus:AA, 5jut:AA, 5juu:AA, 8k2d:LV, 8k82:LV, 5lyb:N3, 5lyb:n3, 5m1j:V5, 6m62:V, 5mc6:AB, 5mei:l2, 5mei:CX, 7mpi:AV, 7mpj:AV, 6n8j:V, 6n8k:V, 6n8l:V, 6n8m:i, 6n8n:i, 6n8o:i, 7n8b:AV, 7nac:V, 7naf:V, 5ndg:N3, 5ndg:n3, 5ndv:N3, 5ndv:n3, 5ndw:N3, 5ndw:n3, 7nrc:LX, 7nrd:LX, 5obm:N3, 5obm:n3, 7of1:V, 7oh3:V, 7ohp:V, 7ohq:V, 7ohr:V, 7ohs:V, 7oht:V, 7ohu:V, 7ohv:V, 7ohy:V, 6oig:V, 5on6:lR, 5on6:CX, 7osa:uL14, 7osm:uL14, 8p8m:QV, 8p8n:QV, 8p8u:QV, 8pfr:QV, 6q8y:AB, 6qik:L, 6qt0:L, 6qtz:L, 7r7a:V, 6r84:x, 6r86:x, 6r87:x, 6ri5:L, 7rr5:LV, 6rzz:L, 6s05:L, 6s47:AX, 6snt:AB, 6sv4:AB, 6sv4:XB, 6sv4:zB, 6t4q:LV, 5t62:i, 5t6r:i, 6t7i:LV, 6t7t:LV, 6t83:Vy, 6t83:G, 5tbw:6, 5tbw:CX, 6tb3:AB, 5tga:N3, 5tga:n3, 5tgm:N3, 5tgm:n3, 6tnu:AB, 7too:AL23, 7top:AL23, 7u0h:V, 4u3m:N3, 4u3m:n3, 4u3n:N3, 4u3n:n3, 4u3u:N3, 4u3u:n3, 4u4n:N3, 4u4n:n3, 4u4o:N3, 4u4o:n3, 4u4q:N3, 4u4q:n3, 4u4r:N3, 4u4r:n3, 4u4u:N3, 4u4u:n3, 4u4y:N3, 4u4y:n3, 4u4z:N3, 4u4z:n3, 4u50:N3, 4u50:n3, 4u51:N3, 4u51:n3, 4u52:N3, 4u52:n3, 4u53:N3, 4u53:n3, 4u55:N3, 4u55:n3, 4u56:N3, 4u56:n3, 4u6f:N3, 4u6f:n3, 7ug6:V, 7uoo:V, 7uqb:V, 7uqz:V, 6uz7:AV, 7v08:V, 4v4b:BR, 4v6i:BM, 4v7f:L, 4v7h:BR, 4v7r:BU, 4v7r:DU, 4v88:BV, 4v88:DV, 4v8t:V, 4v8y:BV, 4v8z:BV, 8v83:V, 8v84:V, 8v87:V, 4v91:V, 6woo:V, 2x7n:C, 6xiq:V, 6xir:V, 8y0u:LV, 6ylg:V, 6ylh:V, 6ylx:V, 6yly:V, 7z34:V, 6z6j:LV, 6z6k:LV, 7zpq:BU, 7zrs:BU, 7zs5:BW, 7zuw:BU, 7zux:EU, 7zw0:LY
2 8c3a:6 131 131 0.8433 0.8626 0.8626 1.59e-83 8c3a:BQ, 8cq7:6, 8cq7:BQ, 8cqw:6, 8cqw:BQ, 8cre:6, 8cre:BQ, 8oeq:6, 8oeq:BQ, 7pzy:6, 7q08:6, 7q0f:6, 7q0p:6, 7q0r:6, 8q5i:6
3 8etc:V 138 132 0.8060 0.7826 0.8182 2.86e-80 8esq:V, 8esr:V, 8etg:V, 8eti:V, 8etj:V, 8eug:V, 8eui:V, 8eup:V
4 7old:LV 137 133 0.8209 0.8029 0.8271 3.19e-79 8i9r:LV, 8i9t:LV, 8i9v:LV, 8i9w:LV, 8i9x:LV, 8i9y:LV, 8i9z:LV, 8ia0:LV, 7olc:LV, 8oo0:LV, 8pv1:LV, 8pv2:LV, 8pv3:LV, 8pv4:LV, 8pv5:LV, 8pv6:LV, 8pv7:LV, 8pv8:LV, 8pvk:LV, 8pvl:LV, 7r81:X1, 7z3n:LV, 7z3o:LV
5 8g5z:LV 140 132 0.7910 0.7571 0.8030 3.10e-77 7a01:k2, 8a3d:P, 5aj0:AV, 8b5l:V, 8b6c:V, 9bdl:AL23, 9bdn:AL23, 9bdp:AL23, 8bhf:I1, 8bpo:U2, 8btk:BV, 7cpu:LV, 7cpv:LV, 4d5y:V, 4d67:V, 6d90:V, 6d9j:V, 9f1b:BV, 9f1c:BV, 9f1d:BV, 7f5s:LV, 8fkt:LG, 8fku:LG, 8fkv:LG, 8fkw:LG, 8fkx:LG, 8fky:LG, 8fkz:LG, 8fl0:LG, 8fl2:LG, 8fl3:LG, 8fl4:LG, 8fl6:LG, 8fl7:LG, 8fl9:LG, 8fla:LG, 8flb:LG, 8flc:LG, 8fld:LG, 8fle:LG, 8flf:LG, 6frk:V, 6ftg:V, 6fti:V, 6ftj:V, 8g5y:LV, 8g60:LV, 8g61:LV, 8g6j:LV, 8glp:LV, 6gz3:AV, 6gz4:AV, 6gz5:AV, 6hcf:V3, 6hcj:V3, 6hcm:V3, 6hcq:V3, 8idt:e, 8idy:e, 8ie3:e, 8ifd:2P, 8ife:2P, 8ine:e, 8inf:e, 8ink:e, 6ip5:2P, 6ip6:2P, 6ip8:2P, 8ipd:e, 8ipx:e, 8ipy:e, 8ir1:e, 8ir3:e, 3j7o:V, 3j7p:V, 3j7q:V, 3j7r:V, 3j92:V, 3jag:V, 3jah:V, 3jai:V, 3jaj:V, 3jan:V, 8jdj:a, 8jdk:a, 8jdl:a, 8jdm:a, 8k2c:LV, 5lks:LV, 6lqm:e, 6lsr:e, 6lss:e, 7ls1:P2, 7ls2:P2, 6lu8:e, 5lzs:V, 5lzt:V, 5lzu:V, 5lzv:V, 5lzw:V, 5lzx:V, 5lzy:V, 5lzz:V, 7mdz:V, 6mtb:V, 6mtc:V, 6mtd:V, 6mte:V, 7nfx:V, 7nwg:V3, 7nwh:V, 7nwi:V, 7o7y:BV, 7o7z:BV, 7o80:BV, 7o81:BV, 7obr:V, 8ohd:LV, 8oj0:LV, 8oj5:LV, 8oj8:LV, 6ole:W, 6olf:W, 6olg:AV, 6oli:W, 6olz:AV, 6om0:W, 6om7:W, 7ow7:Q, 7oya:V1, 7oyb:V1, 7oyc:V1, 7oyd:V, 8p2k:BV, 6p5i:AV, 6p5j:AV, 6p5k:AV, 6p5n:AV, 8q7z:BV, 8q87:BV, 8qfd:V, 7qgg:W, 8qoi:LV, 7qvp:LV, 7qvp:MV, 7qwq:V, 7qwr:V, 7qws:V, 6qzp:LV, 6r5q:V, 6r6g:V, 6r6p:V, 6r7q:V, 8rjb:V, 8rjc:V, 8rjd:V, 8scb:V, 6sgc:V2, 6swa:T, 5t2c:P, 6t59:V3, 7tm3:V, 7toq:AL23, 7tor:AL23, 7tut:V, 7ucj:V, 7uck:V, 4ug0:LV, 4ujc:BV, 4ujd:AV, 4uje:CV, 4v5z:Bk, 4v6x:CV, 6w6l:W, 6xa1:LV, 7xnx:LV, 7xny:LV, 8xsx:LV, 8xsy:LV, 8xsz:LV, 6y0g:LV, 8y0w:LV, 8y0x:LV, 6y2l:LV, 6y57:LV, 6y6x:LV, 8yoo:LV, 8yop:LV, 6z6l:LV, 6z6m:LV, 6z6n:LV, 7zjw:LY, 7zjx:LY, 6zm7:LV, 6zme:LV, 6zmi:LV, 6zmo:LV, 6zvk:k2
6 4v3p:LM 140 133 0.7612 0.7286 0.7669 2.21e-75 8azw:e, 8b2l:e3, 8ip8:GA, 8ipa:GA, 8ipb:GA, 8jiv:CV, 7qiw:X, 7qiz:X, 4v7e:CV
7 6zj3:LY 134 130 0.7687 0.7687 0.7923 6.32e-75
8 4v6w:CV 134 129 0.7687 0.7687 0.7984 2.78e-74 6xu6:CV, 6xu7:CV, 6xu8:CV
9 3j79:M 132 128 0.6866 0.6970 0.7188 1.21e-68 3jbn:AM, 3jbo:AM, 3jbp:AM, 8tpu:AM, 5umd:M
10 4v8m:BW 138 131 0.6716 0.6522 0.6870 3.28e-68 8a3w:J, 8a98:J, 6az3:J, 3jcs:J, 8ova:BW, 8ove:BW, 8ovj:J, 8rxh:LJ, 8rxx:LJ, 5t2a:U, 5t5h:W
11 5an9:E 136 132 0.7015 0.6912 0.7121 8.33e-68 5anb:E, 5anc:E, 6qkl:E
12 9bh5:CV 128 127 0.6791 0.7109 0.7165 1.11e-67 9cai:CV
13 5xxb:U 129 123 0.6791 0.7054 0.7398 1.63e-67
14 4v8p:BJ 138 133 0.7164 0.6957 0.7218 1.65e-63 4v8p:CJ, 4v8p:EJ, 4v8p:GJ
15 7ohw:V 98 115 0.7313 1.0000 0.8522 1.80e-62
16 8euy:V 113 132 0.6940 0.8230 0.7045 1.01e-60
17 7pwg:V 139 134 0.6493 0.6259 0.6493 3.18e-60 8br8:LW, 8brm:LW, 8bsi:LW, 8bsj:LW, 8btd:LW, 8btr:LW, 8fru:V, 7pwo:V2
18 5xy3:V 134 128 0.6343 0.6343 0.6641 7.50e-60
19 6zu5:LV0 138 128 0.5000 0.4855 0.5234 3.73e-47
20 7qep:N3 135 127 0.5000 0.4963 0.5276 1.62e-45
21 8p5d:LV0 141 127 0.4478 0.4255 0.4724 4.76e-41 8p60:LV0, 8p60:KV0, 7qca:LV0
22 6rm3:LV0 135 123 0.4851 0.4815 0.5285 7.33e-41
23 4v4n:AJ 132 129 0.4403 0.4470 0.4574 1.22e-36 4v6u:BJ
24 3cc2:K 132 125 0.4030 0.4091 0.4320 2.14e-33 3cc4:K, 3cc7:K, 3cce:K, 3ccj:K, 3ccl:K, 3ccm:K, 3ccq:K, 3ccr:K, 3ccs:K, 3ccu:K, 3ccv:K, 3cd6:K, 3cma:K, 3cme:K, 3cpw:J, 3cxc:J, 1ffk:H, 3g4s:K, 3g6e:K, 3g71:K, 3i55:K, 3i56:K, 1jj2:J, 1k73:L, 1k8a:L, 1k9m:L, 1kc8:L, 1kd1:L, 1kqs:J, 1m1k:L, 1m90:L, 1n8r:L, 1nji:L, 2otj:K, 2otl:K, 3ow2:J, 1q7y:L, 1q81:L, 1q82:L, 1q86:L, 2qa4:K, 2qex:K, 1qvf:J, 1qvg:J, 1s72:K, 4v9f:K, 1vq4:K, 1vq5:K, 1vq6:K, 1vq7:K, 1vq8:K, 1vq9:K, 1vqk:K, 1vql:K, 1vqm:K, 1vqn:K, 1vqo:K, 1vqp:K, 1w2b:J, 1yhq:K, 1yi2:K, 1yij:K, 1yit:K, 1yj9:K, 1yjn:K, 1yjw:K
25 8hku:L14P 134 113 0.3806 0.3806 0.4513 5.05e-32 8hkv:L14P, 8hky:L14P, 8hkz:L14P, 8hl1:L14P, 8hl2:L14P, 8hl3:L14P, 8hl4:L14P, 8hl5:L14P
26 6skf:BL 140 127 0.4403 0.4214 0.4646 6.69e-28 6skg:BL, 6th6:BL
27 5h1s:M 121 112 0.2910 0.3223 0.3482 2.69e-17 6eri:AK, 5mlc:M, 5mmi:L, 5mmm:L, 4v61:BM, 5x8p:L, 5x8t:L
28 7jil:K 121 102 0.2985 0.3306 0.3922 2.81e-16
29 4v4p:AN 122 106 0.3209 0.3525 0.4057 2.10e-15 4v4r:BO, 4v4s:BO, 4v4t:BO
30 7ood:j 122 105 0.3060 0.3361 0.3905 3.96e-15 7p6z:j, 7pah:j, 7pai:j, 7paj:j, 7pak:j, 7pal:j, 7pam:j, 7pan:j, 7pao:j, 7paq:j, 7par:j, 7pas:j, 7pat:j, 7pau:j, 7ph9:j, 7pha:j, 7phb:j, 7phc:j, 7pi8:j, 7pi9:j, 7pia:j, 7pib:j, 7pic:j, 7pio:j, 7pip:j, 7piq:j, 7pir:j, 7pis:j, 7pit:j
31 7unr:M 122 104 0.3134 0.3443 0.4038 4.36e-15 8cd1:K, 6spb:K, 6spd:K, 6spf:K, 6spg:K, 7unu:M, 7unv:M, 7unw:M
32 8a57:N 122 102 0.2910 0.3197 0.3824 1.13e-14 8a5i:N, 8a63:N, 7aqc:K, 7aqd:K, 7as8:O, 7as9:O, 7asm:I, 7asn:G, 7aso:N, 7asp:I, 8buu:K, 6ddd:W, 6ddg:W, 6fxc:AI, 6fxc:BI, 6ha1:K, 6ha8:K, 5hkv:H, 5hl7:H, 6hma:I, 6htq:K, 3j3v:K, 3j3w:K, 3j9w:BN, 5li0:N, 5nd8:N, 5nd9:N, 5ngm:AI, 7nhk:N, 7nhl:N, 7nhm:N, 7nhn:N, 5njt:d, 5nrg:H, 7o5b:f, 6o8w:L, 6o8x:L, 6o8y:L, 6o8z:L, 6o90:L, 7ope:O, 8p2f:N, 8p2g:N, 8p2h:N, 7p48:I, 7p7q:N, 7p7r:N, 7p7s:N, 7p7t:N, 7p7u:N, 6ppf:K, 6ppk:K, 6pvk:K, 8qcq:K, 7qgu:K, 7qh4:K, 8qpp:f, 7qv1:K, 7qv2:K, 7qv3:K, 8r55:f, 6s0x:I, 6s0z:I, 6s12:I, 6s13:I, 8s1p:K, 8s1u:K, 7s9u:K, 7sae:K, 6sj6:N, 5t7v:LN, 5tcu:LN, 6tnn:d, 6tpq:d, 7ttu:W, 7ttw:W, 8uu4:M, 8uu5:M, 8uu6:M, 8uu7:M, 8uu8:M, 8uu9:M, 8uua:M, 6w6p:L, 4wce:H, 4wf9:H, 4wfa:H, 4wfb:H, 6wqn:W, 6wqq:W, 6wrs:W, 6wru:W, 6wu9:L, 8y36:I, 8y37:I, 8y38:I, 8y39:I, 6yef:N
33 7m4v:J 122 104 0.3209 0.3525 0.4135 1.42e-14 7m4w:J, 7m4x:J, 7m4y:J, 7m4z:J, 8rd8:Je, 8rdv:Je, 8rdw:Je, 7ryf:J, 7ryg:J, 7ryh:J, 7uvv:J, 7uvw:J, 7uvx:J, 7uvy:J, 7uvz:J, 7uw1:J, 6v39:J, 6v3a:J, 6v3b:J, 6v3d:J, 6yhs:G, 6ysi:G
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42 7nad:V 36 58 0.2388 0.8889 0.5517 3.56e-09
43 6xyw:Ak 127 116 0.2836 0.2992 0.3276 1.33e-07
44 5mrc:I 127 108 0.2836 0.2992 0.3519 1.86e-04 3j6b:I, 5mre:I, 5mrf:I
45 7pkt:j 120 124 0.2612 0.2917 0.2823 0.002
46 8a22:Ai 121 100 0.1940 0.2149 0.2600 0.12 8apn:Ai, 8apo:Ai
47 3aj4:A 112 71 0.1716 0.2054 0.3239 1.0
48 1g0o:C 281 33 0.1045 0.0498 0.4242 1.2 1doh:A, 1doh:B, 1g0n:A, 1g0n:B, 1g0o:A, 1g0o:B, 1g0o:D, 1ybv:A, 1ybv:B
49 6z1p:Ap 119 96 0.1642 0.1849 0.2292 1.6
50 7qep:M5 203 103 0.1940 0.1281 0.2524 3.1
51 3o32:A 256 59 0.1493 0.0781 0.3390 3.2 3o32:B, 3o5u:A, 3o5u:B, 3o6j:A, 3o6j:B, 3o6r:A, 3o6r:B, 1s9a:A, 1s9a:B
52 1dos:A 358 72 0.1418 0.0531 0.2639 6.5 1b57:A, 1b57:B, 1dos:B, 5vjd:A, 5vjd:B, 5vje:A, 5vje:B, 1zen:A
53 3tkt:A 411 36 0.1194 0.0389 0.4444 6.5
54 7nh7:A 295 46 0.1194 0.0542 0.3478 7.1
55 5gk5:C 335 72 0.1418 0.0567 0.2639 9.8 5gk3:A, 5gk3:B, 5gk4:A, 5gk4:B, 5gk5:A, 5gk5:B, 5gk5:D, 5gk5:E, 5gk5:F, 5gk5:G, 5gk5:H, 5gk6:A, 5gk6:B, 5gk7:A, 5gk7:B, 5gk8:A, 5gk8:B, 1gyn:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218