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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NELPGTSDTPLLDQIHGPKDLKRLSREQLPALTEELRGEIVRVCSRGGLHLASSLGAVDIITALHYVLDSPRDRILFDVG
HQAYAHKILTGRRDQMADIKKEGGISGFTKVSESEHDAITVGHASTSLANALGMALARDAQGKDFHVAAVIGDGSLTGGM
ALAALNTIGDMGRKMLIVLNDNEMNPFAAMGVRYVGPVDGHNVQELVWLLERLVDLDGPTILHIVTTKGKGSAYSWSAAF
GEAVTEWAKTDPRTFVVTPAMREGSGLVEFSRVHPHRYLDVGIAEEVAVTTAAGMALQGMRPVVAIYSTFLQRAYDQVLH
DVAIEHLNVTFCIDRAGIVGADGATHNGVFDLSFLRSIPGVRIGLPKDAAELRGMLKYAQTHDGPFAIRYPRGNTAQVPA
GTWPDLKWGEWERLKGGDDVVILAGGKALDYALKAAEDLPGVGVVNARFVKPLDEEMLREVGGRARALITVEDNTVVGGF
GGAVLEALNSMNLHPTVRVLGIPDEFQEHATAESVHARAGIDAPAIRTVLAELGVDVPI

The query sequence (length=539) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6xxg:BBB 539 539 1.0000 1.0000 1.0000 0.0 2o1x:C, 2o1x:D
2 6ouv:A 595 593 0.9889 0.8958 0.8988 0.0 2o1x:A, 2o1x:B, 6ouv:B, 8v9i:A, 8v9i:B
3 6xxg:AAA 560 560 0.9814 0.9446 0.9446 0.0 6ouw:A
4 2o1s:A 536 520 0.4675 0.4701 0.4846 3.12e-160 2o1s:C
5 8a45:F 573 560 0.4750 0.4468 0.4571 1.87e-159 8a29:A, 8a29:B, 8a29:C, 8a29:D, 8a29:E, 8a29:F, 8a45:A, 8a45:B, 8a45:C, 8a45:D, 8a45:E, 8a4d:A, 8a4d:B, 8a4d:C, 8a4d:D, 8a4d:E, 8a4d:F, 8a5k:A, 8a5k:B, 8a5k:C, 8a5k:D, 8a5k:E, 8a5k:F
6 8bzx:A 546 534 0.4601 0.4542 0.4644 2.24e-150
7 8bzx:B 568 555 0.4601 0.4366 0.4468 1.52e-147
8 8a9c:B 520 522 0.4434 0.4596 0.4579 1.26e-141
9 2o1s:B 493 516 0.4378 0.4787 0.4574 1.42e-139 2o1s:D
10 7a9g:AAA 549 541 0.4230 0.4153 0.4214 4.19e-126 7a9g:BBB, 7a9h:AAA, 7a9h:BBB, 8ogh:A, 8ogh:B
11 8r2h:B 701 585 0.3488 0.2682 0.3214 2.61e-90 8r2h:A
12 6yak:DDD 311 293 0.1781 0.3087 0.3276 1.90e-41 6yak:BBB
13 6rjb:B 622 262 0.1391 0.1206 0.2863 1.53e-20 6ha3:A, 6had:A, 4kxu:A, 4kxv:A, 4kxw:A, 4kxx:A, 4kxy:A, 4kxy:B, 3mos:A, 3ooy:A, 3ooy:B, 6rjb:A, 8wa8:A, 8wa9:A, 8wa9:B, 8waa:A, 8waa:B
14 3duf:D 324 262 0.1317 0.2191 0.2710 1.81e-08 3duf:B, 3duf:H, 3duf:F, 3dv0:D, 3dv0:B, 3dv0:H, 3dv0:F, 3dva:D, 3dva:B, 3dva:H, 3dva:F, 1w85:D, 1w85:B, 1w85:H, 1w85:F, 1w88:D, 1w88:B, 1w88:H
15 1qs0:B 338 261 0.1262 0.2012 0.2605 1.90e-07
16 6yak:AAA 282 270 0.1187 0.2270 0.2370 3.64e-07 6yak:CCC
17 4c7x:A 662 195 0.1020 0.0831 0.2821 5.57e-07
18 4c7x:A 662 149 0.0816 0.0665 0.2953 1.22e-04
19 8cip:A 665 195 0.1039 0.0842 0.2872 6.58e-07 8cip:B, 8cip:C, 8cip:D
20 8cip:A 665 233 0.1076 0.0872 0.2489 0.001 8cip:B, 8cip:C, 8cip:D
21 5vrb:B 646 194 0.0946 0.0789 0.2629 2.52e-06 5vrb:D
22 5vrb:B 646 196 0.0965 0.0805 0.2653 2.85e-05 5vrb:D
23 6cer:D 331 293 0.1169 0.1903 0.2150 3.19e-06 6cer:B, 6cer:H, 6cer:F, 6cfo:D, 6cfo:B, 3exe:D, 3exe:B, 3exe:H, 3exe:F, 3exf:D, 3exf:B, 3exf:H, 3exf:F, 3exh:D, 3exh:B, 3exh:H, 3exh:F, 1ni4:D, 1ni4:B, 2ozl:D, 2ozl:B
24 1umb:D 323 291 0.1317 0.2198 0.2440 3.48e-06 1umb:B, 1umc:D, 1umc:B, 1umd:D, 1umd:B
25 8qmf:A 678 211 0.1039 0.0826 0.2654 5.98e-06 8qmf:B
26 8qmf:A 678 163 0.0761 0.0605 0.2515 0.22 8qmf:B
27 3m34:A 632 262 0.1317 0.1123 0.2710 1.00e-05 3m6l:A, 3m7i:A
28 3m34:A 632 219 0.1058 0.0902 0.2603 0.011 3m6l:A, 3m7i:A
29 8r3o:B 667 173 0.0872 0.0705 0.2717 2.01e-05 8r3o:A, 8r3o:C, 8r3o:D
30 8r3o:B 667 224 0.0965 0.0780 0.2321 0.003 8r3o:A, 8r3o:C, 8r3o:D
31 8r3p:A 672 130 0.0724 0.0580 0.3000 3.02e-05 8r3p:B, 8r3p:C, 8r3p:D
32 8r3p:A 672 283 0.1187 0.0952 0.2261 8.74e-04 8r3p:B, 8r3p:C, 8r3p:D
33 1r9j:B 671 182 0.0928 0.0745 0.2747 3.49e-05 1r9j:A
34 1r9j:B 671 129 0.0631 0.0507 0.2636 0.61 1r9j:A
35 2j9f:D 329 254 0.1113 0.1824 0.2362 8.23e-05 1dtw:B, 2j9f:B
36 5vrb:A 627 196 0.0946 0.0813 0.2602 8.65e-05 5vrb:C
37 5vrb:A 627 193 0.0891 0.0766 0.2487 3.29e-04 5vrb:C
38 8r3r:A 658 176 0.0872 0.0714 0.2670 1.33e-04 8r3r:B, 8r3r:C, 8r3r:D
39 4xeu:A 632 238 0.1113 0.0949 0.2521 1.59e-04
40 4xeu:A 632 178 0.0891 0.0759 0.2697 0.003
41 3upt:A 671 184 0.0872 0.0700 0.2554 2.07e-04 3upt:B
42 3upt:A 671 195 0.0909 0.0730 0.2513 5.68e-04 3upt:B
43 8r3q:D 676 188 0.0891 0.0710 0.2553 3.46e-04 8r3q:B, 8r3q:A, 8r3q:C
44 8r3q:D 676 172 0.0816 0.0651 0.2558 0.005 8r3q:B, 8r3q:A, 8r3q:C
45 8r3s:A 663 193 0.0891 0.0724 0.2487 0.001 8r3s:B, 8r3s:C, 8r3s:D, 8r3s:E, 8r3s:F, 8r3s:G, 8r3s:H, 8r3s:I, 8r3s:J
46 8r3s:A 663 174 0.0928 0.0754 0.2874 0.002 8r3s:B, 8r3s:C, 8r3s:D, 8r3s:E, 8r3s:F, 8r3s:G, 8r3s:H, 8r3s:I, 8r3s:J
47 5hht:B 667 180 0.0835 0.0675 0.2500 0.002 5hht:A, 1qgd:A, 1qgd:B, 2r5n:A, 2r5n:B, 2r8o:A, 2r8o:B, 2r8p:A, 2r8p:B, 6rjc:A, 6rjc:B, 6tj8:A, 6tj8:B, 6tj9:A, 6tj9:B, 8wa7:A, 8wa7:B
48 5hht:B 667 251 0.1076 0.0870 0.2311 0.004 5hht:A, 1qgd:A, 1qgd:B, 2r5n:A, 2r5n:B, 2r8o:A, 2r8o:B, 2r8p:A, 2r8p:B, 6rjc:A, 6rjc:B, 6tj8:A, 6tj8:B, 6tj9:A, 6tj9:B, 8wa7:A, 8wa7:B
49 1ay0:A 678 167 0.0705 0.0560 0.2275 0.004 1ay0:B, 1gpu:A, 1gpu:B, 1ngs:A, 1ngs:B, 1tka:A, 1tka:B, 1tkb:A, 1tkb:B, 1tkc:A, 1tkc:B, 1trk:A, 1trk:B
50 1ay0:A 678 202 0.0853 0.0678 0.2277 3.6 1ay0:B, 1gpu:A, 1gpu:B, 1ngs:A, 1ngs:B, 1tka:A, 1tka:B, 1tkb:A, 1tkb:B, 1tkc:A, 1tkc:B, 1trk:A, 1trk:B
51 5nd5:A 669 207 0.0946 0.0762 0.2464 0.009 5nd5:B
52 5nd5:A 669 175 0.0686 0.0553 0.2114 0.75 5nd5:B
53 7wrr:A 650 133 0.0668 0.0554 0.2707 0.013 7wrr:B, 7wrr:C, 7wrr:D, 7wrt:A, 7wrt:B, 7wrt:C, 7wrt:D
54 7wrr:A 650 128 0.0631 0.0523 0.2656 4.1 7wrr:B, 7wrr:C, 7wrr:D, 7wrt:A, 7wrt:B, 7wrt:C, 7wrt:D
55 8ci0:AAA 666 197 0.0872 0.0706 0.2386 0.018 8ci0:BBB, 8ci0:CCC, 1itz:A, 1itz:B, 1itz:C
56 8ci0:AAA 666 192 0.0816 0.0661 0.2292 0.23 8ci0:BBB, 8ci0:CCC, 1itz:A, 1itz:B, 1itz:C
57 3m49:A 665 195 0.0909 0.0737 0.2513 0.019 3hyl:A, 3hyl:B, 3m49:B
58 3m49:A 665 147 0.0724 0.0586 0.2653 0.054 3hyl:A, 3hyl:B, 3m49:B
59 5hje:A 676 200 0.0835 0.0666 0.2250 0.022 5hyv:A, 5i51:A, 5i5e:A, 5i5g:A, 5xps:A, 5xqa:A, 5xqk:A, 5xrv:A, 5xry:A, 5xs6:A, 5xsa:A, 5xsb:A, 5xsm:A, 5xt0:A, 5xt4:A, 5xtl:A, 5xtv:A, 5xtx:A, 5xu2:A, 5xu9:A, 5xuf:A, 5xvt:A
60 3rim:A 694 98 0.0557 0.0432 0.3061 0.083 3rim:C, 3rim:B, 3rim:D
61 3rim:A 694 164 0.0705 0.0548 0.2317 6.2 3rim:C, 3rim:B, 3rim:D
62 3ey9:A 571 125 0.0575 0.0543 0.2480 1.2 3ey9:B, 3eya:A, 3eya:B, 3eya:C, 3eya:D, 3eya:E, 3eya:F, 3eya:G, 3eya:H, 3eya:I, 3eya:J, 3eya:K, 3eya:L
63 2gu2:A 307 42 0.0260 0.0456 0.3333 1.4 2gu2:B, 2q4z:B
64 6pwj:A 408 44 0.0278 0.0368 0.3409 3.7 6pwj:B, 6pwk:A, 6pwk:B
65 4mri:B 303 42 0.0223 0.0396 0.2857 4.6 2i3c:A, 2i3c:B, 4mri:A, 4mxu:A, 4mxu:B, 4nfr:A, 4nfr:B, 2o4h:A, 2o4h:B, 2o53:A, 2o53:B, 2q51:A, 2q51:B, 4tnu:A, 4tnu:B
66 6vu9:A 631 85 0.0501 0.0428 0.3176 8.5
67 2xf4:A 210 97 0.0482 0.1238 0.2680 8.8
68 4ici:A 159 32 0.0260 0.0881 0.4375 9.4

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218