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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKS

The query sequence (length=39) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5cq2:A 76 39 0.9744 0.5000 0.9744 3.06e-23 5dws:A, 5dws:E, 5dws:G, 5dzd:A, 5dzd:B, 2jo9:A, 4rof:A, 4rof:B
2 2jmf:A 43 38 0.5897 0.5349 0.6053 2.60e-11
3 2lb1:A 35 32 0.5641 0.6286 0.6875 2.31e-10 2ltx:A
4 6jjz:B 96 35 0.4872 0.1979 0.5429 5.98e-10 6jjz:A, 6kkg:A, 6kkg:B
5 6jjz:B 96 33 0.3333 0.1354 0.3939 8.5 6jjz:A, 6kkg:A, 6kkg:B
6 2djy:A 42 32 0.5385 0.5000 0.6562 8.66e-10
7 2kxq:A 90 32 0.5385 0.2333 0.6562 2.78e-09 2laz:A, 2lb0:A, 2ltz:A
8 2kxq:A 90 31 0.3590 0.1556 0.4516 0.029 2laz:A, 2lb0:A, 2ltz:A
9 2m3o:W 43 31 0.4615 0.4186 0.5806 5.07e-09 2kpz:A, 2kq0:A, 2mpt:A, 4n7h:A
10 2laj:A 40 31 0.4872 0.4750 0.6129 9.56e-09
11 2ez5:W 46 38 0.4615 0.3913 0.4737 1.11e-08
12 4lcd:A 419 36 0.5641 0.0525 0.6111 1.58e-08 4lcd:B
13 6jjy:A 128 34 0.5128 0.1562 0.5882 1.94e-08 6j68:A, 6j68:B, 6j69:A, 6jjw:A, 6jjx:B, 6jjx:A
14 6jjy:A 128 31 0.3846 0.1172 0.4839 0.002 6j68:A, 6j68:B, 6j69:A, 6jjw:A, 6jjx:B, 6jjx:A
15 2ltv:A 36 32 0.4103 0.4444 0.5000 2.45e-08 2law:A
16 5dws:C 40 33 0.4615 0.4500 0.5455 5.76e-07
17 1jmq:A 46 37 0.4615 0.3913 0.4865 1.14e-06 1k5r:A, 1k9q:A, 1k9r:A, 2lax:A, 2lay:A, 2ltw:A
18 1i5h:W 50 32 0.4103 0.3200 0.5000 5.82e-06
19 7lp2:E 37 30 0.4103 0.4324 0.5333 1.16e-05 2lb2:A, 7lp2:A, 7lp2:C, 2lty:A
20 2n8t:A 39 30 0.3846 0.3846 0.5000 8.36e-05
21 7lp3:A 37 31 0.3846 0.4054 0.4839 4.43e-04 7lp3:C
22 5xyi:E 246 25 0.2564 0.0407 0.4000 0.024
23 1eg4:A 260 27 0.2051 0.0308 0.2963 0.063
24 2nc3:A 33 30 0.2564 0.3030 0.3333 0.16 2nc4:A, 2nc5:A, 2nc6:A
25 8c3a:CR 260 18 0.2564 0.0385 0.5556 0.95 8c3a:G, 8cq7:G, 8cq7:CR, 8cqw:G, 8cqw:CR, 8cre:G, 8cre:CR, 8oeq:G, 8oeq:CR, 7pzy:F, 7q08:F, 7q0f:F, 7q0p:F, 7q0r:F, 8q5i:F
26 3ngl:A 275 22 0.2564 0.0364 0.4545 0.95 3ngl:C
27 6heg:A 783 28 0.2821 0.0140 0.3929 1.1
28 6iym:A 277 28 0.2821 0.0397 0.3929 1.1 6iym:B
29 6fec:I 263 18 0.2564 0.0380 0.5556 1.2 7a01:j3, 7a09:q, 5a2q:E, 5aj0:BE, 9bdl:AS04, 9bdn:AS04, 9bdp:AS04, 8bhf:F3, 9bkd:C, 9bln:C, 8btk:Ad, 7cpu:SE, 7cpv:SE, 4d5l:E, 4d61:E, 6d90:FF, 6d9j:FF, 9f1b:Ad, 9f1c:Ad, 9f1d:Ad, 5flx:E, 6g18:E, 6g4s:E, 6g4w:E, 6g51:E, 6g53:E, 6g5h:E, 6g5i:E, 8g5y:SE, 8g5z:SE, 8g60:SE, 8g61:SE, 8g6j:SE, 8glp:SE, 6gz3:BE, 6gz4:BE, 6gz5:BE, 6hcf:F1, 6hcj:F2, 6hcm:F1, 6hcq:F2, 8ifd:2q, 8ife:2q, 6ip5:2q, 6ip6:2q, 6ip8:2q, 3j7p:SE, 3j7r:SE, 3jag:EE, 3jah:EE, 3jai:EE, 3jaj:SE, 3jan:SE, 8jdj:1, 8jdk:1, 8jdl:1, 8jdm:1, 7jqb:M, 7jqc:M, 5k0y:I, 8k2c:SE, 7k5i:E, 4kzx:E, 4kzy:E, 4kzz:E, 5lks:SE, 7ls1:r2, 7ls2:r2, 5lzs:EE, 5lzt:EE, 5lzu:EE, 5lzv:EE, 5lzw:EE, 5lzx:EE, 5lzy:EE, 5lzz:EE, 7mdz:EE, 7mq8:L4, 7mq9:L4, 7mqa:L4, 6mtb:EE, 6mtc:EE, 6mtd:EE, 6mte:EE, 7nwg:F2, 7nwh:EE, 7nwi:EE, 7o7y:Ad, 7o7z:Ad, 7o80:Ad, 7o81:Ad, 5oa3:E, 6ole:SE, 6olf:SE, 6olg:BE, 6oli:SE, 6olz:BE, 6om0:SE, 6om7:SE, 7oya:E2, 7oyb:E2, 7oyc:E2, 7oyd:EE, 8oz0:Y, 8p03:G, 8p09:G, 8p2k:Ad, 6p4g:F, 6p4h:F, 6p5i:F, 6p5j:F, 6p5k:F, 6p5n:F, 8pj1:C, 8pj2:C, 8pj3:C, 8pj4:C, 8pj5:C, 8pj6:C, 8ppk:E, 8ppl:AE, 8q7z:Ad, 8q87:Ad, 7qgg:SE, 8qoi:SE, 7qp6:C, 7qp7:C, 7qvp:RE, 7qvp:SE, 6qzp:SE, 7r4x:E, 6r5q:x, 6r6g:x, 6r6p:x, 6r7q:x, 8scb:EE, 6sgc:F1, 7syg:F, 7syh:F, 7syi:F, 7syj:F, 7syk:F, 7syl:F, 7sym:F, 7syn:F, 7syo:F, 7syp:F, 7syq:F, 7syr:F, 7sys:F, 7syt:F, 7syu:F, 7syv:F, 7syw:F, 7syx:F, 5t2c:Ar, 8t4s:E, 7toq:AS04, 7tor:AS04, 7tql:E, 7ucj:EE, 7uck:EE, 4ug0:SE, 4ujc:CE, 4ujd:CE, 4uje:BE, 4v6x:AE, 5vyc:E1, 5vyc:E2, 5vyc:E3, 5vyc:E4, 5vyc:E5, 5vyc:E6, 6w2s:F, 6w2t:F, 7wts:E, 7wtt:E, 7wtu:E, 7wtv:E, 7wtw:E, 7wtx:E, 7wtz:E, 7wu0:E, 6xa1:SE, 7xnx:SE, 7xny:SE, 8xsx:SE, 8xsy:SE, 8xsz:SE, 8xxl:SE, 8xxm:SE, 8xxn:SE, 6y0g:SE, 8y0w:SE, 8y0x:SE, 6y2l:SE, 6y57:SE, 6yal:G, 6yam:G, 6yan:G, 6ybw:C, 8yoo:SE, 8yop:SE, 6z6l:SE, 6z6m:SE, 6z6n:SE, 7zjw:SP, 7zjx:SP, 6zlw:E, 6zm7:SE, 6zme:SE, 6zmi:SE, 6zmo:SE, 6zmt:E, 6zmw:C, 6zn5:E, 6zoj:E, 6zok:E, 6zon:q, 6zp4:q, 6zuo:E, 6zv6:E, 6zvh:E, 6zvj:q, 6zvk:j3, 6zxd:E, 6zxe:E, 6zxf:E, 6zxg:E, 6zxh:E
30 8bn3:S4 260 18 0.2564 0.0385 0.5556 1.2 7a1g:S, 7ajt:DE, 7aju:DE, 7b7d:S, 8bqd:S, 8bqx:S, 8c00:S, 8c01:S, 8c83:S, 8cah:S, 8cas:S, 8cbj:E, 8ccs:h, 8cdl:h, 8cdr:h, 8ceh:h, 8cf5:h, 8cg8:h, 8cgn:h, 8civ:h, 8cku:h, 8cmj:h, 7d4i:SF, 7d5t:SF, 7d63:SF, 5dat:S4, 5dat:s4, 5dc3:S4, 5dc3:s4, 5dge:S4, 5dge:s4, 5dgf:S4, 5dgf:s4, 5dgv:S4, 5dgv:s4, 6eml:S, 8eub:BE, 8evp:BE, 8evq:BE, 8evr:BE, 8evs:BE, 8evt:BE, 8ewb:BE, 8ewc:BE, 6fai:E, 5fci:S4, 5fci:s4, 5fcj:S4, 5fcj:s4, 6fyx:E, 6fyy:E, 6gq1:u, 6gqb:u, 6gqv:u, 6gsm:E, 6gsn:E, 6hhq:F, 6hhq:s4, 5i4l:S4, 5i4l:s4, 6i7o:Sb, 6i7o:S, 8i7j:E, 5it7:E, 5it9:E, 3j6x:S4, 3j6y:S4, 3j77:S4, 3j78:S4, 3j80:E, 3j81:E, 3jam:E, 3jap:E, 5juo:BB, 5jup:BB, 5jus:BB, 5jut:BB, 5juu:BB, 8k2d:SE, 8k82:SE, 6ke6:SF, 5ll6:S, 6lqp:SF, 6lqq:SF, 6lqr:SF, 6lqs:SF, 6lqt:SF, 6lqu:SF, 6lqv:SF, 5lyb:S4, 5lyb:s4, 5m1j:E2, 5mc6:S, 5mei:s4, 5mei:F, 7mpi:BE, 7mpj:BE, 7n8b:BE, 5ndg:S4, 5ndg:s4, 5ndv:S4, 5ndv:s4, 5ndw:S4, 5ndw:s4, 7nrc:SS, 7nrd:SS, 5obm:S4, 5obm:s4, 5on6:s4, 5on6:F, 7osa:eS4, 7osm:eS4, 6q8y:S, 6rbd:E, 6rbe:E, 7rr5:SE, 8rw1:E, 6s47:BF, 8s8d:E, 8s8e:E, 8s8f:E, 8s8g:E, 8s8h:E, 8s8i:E, 8s8j:E, 6snt:E, 7suk:L4, 6sv4:Sb, 6sv4:S, 6sv4:Sc, 6t4q:SE, 6t7i:SE, 6t7t:SE, 6t83:Eb, 6t83:f, 5tbw:F, 5tbw:s4, 6tb3:S, 5tga:S4, 5tga:s4, 5tgm:S4, 5tgm:s4, 6tnu:S, 5tzs:5, 4u3m:S4, 4u3m:s4, 4u3n:S4, 4u3n:s4, 4u3u:S4, 4u3u:s4, 4u4n:S4, 4u4n:s4, 4u4o:S4, 4u4o:s4, 4u4q:S4, 4u4q:s4, 4u4r:S4, 4u4r:s4, 4u4u:S4, 4u4u:s4, 4u4y:S4, 4u4y:s4, 4u4z:S4, 4u4z:s4, 4u50:S4, 4u50:s4, 4u51:S4, 4u51:s4, 4u52:S4, 4u52:s4, 4u53:S4, 4u53:s4, 4u55:S4, 4u55:s4, 4u56:S4, 4u56:s4, 4u6f:S4, 4u6f:s4, 4uer:W, 6uz7:E, 4v6i:AD, 4v88:AE, 4v88:CE, 4v8y:AE, 4v8z:AE, 4v92:BE, 6wdr:E, 5wlc:L4, 6woo:EE, 7wtl:SE, 7wtm:SE, 7wtn:SE, 7wto:SE, 7wtp:SE, 7wtq:SE, 7wtr:SE, 5wyj:SF, 5wyk:SF, 6xiq:u, 6xir:u, 8y0u:SE, 6y7c:E, 6z6j:SE, 6z6k:SE, 6zce:F, 7zpq:AE, 6zqb:DE, 6zqc:DE, 6zqd:DE, 6zqe:DE, 6zqf:DE, 6zqg:DE, 7zrs:AE, 6zu9:S, 7zuw:AE, 7zux:DE, 6zvi:m, 7zw0:sS
31 7olc:SE 261 18 0.2308 0.0345 0.5000 1.5 7old:SE, 8oo0:SE, 5oql:m, 7r81:F2, 6rxu:Cb, 6rxv:Cb, 6rxx:Cb, 6rxz:Cb, 7z3n:SE, 7z3o:SE
32 4v6w:AE 261 23 0.2308 0.0345 0.3913 1.6 6xu6:AE, 6xu7:AE, 6xu8:AE
33 2a06:E 196 29 0.3590 0.0714 0.4828 1.7 2a06:R, 1bcc:E, 2bcc:E, 3bcc:E, 1be3:E, 1bgy:Q, 4d6t:R, 4d6u:R, 7dkf:Q1, 2fyu:E, 5gpn:E, 5gpn:Q, 5gup:2, 5gup:4, 6haw:E, 8iog:C, 8iog:c, 5j4z:AE, 5j4z:AP, 5j7y:AE, 5j7y:AP, 5j8k:AE, 5j8k:AP, 5klv:E, 1l0l:E, 1l0n:E, 5luf:q, 6nhg:E, 5nmi:E, 1ntk:E, 1ntm:E, 1ntz:E, 1nu1:E, 7o37:E, 7o37:P, 7o3c:E, 7o3c:P, 7o3h:E, 7o3h:P, 5okd:E, 8p65:E, 8p65:R, 1pp9:R, 1pp9:E, 1ppj:R, 1ppj:E, 8pw5:E, 8pw5:P, 8pw6:E, 8pw6:P, 8pw7:E, 8pw7:P, 6q9e:f1, 6q9e:f2, 6qbx:f1, 6qbx:f2, 6qc2:f1, 6qc2:f2, 6qc3:f1, 6qc3:f2, 6qc4:f1, 6qc4:f2, 7r3v:E, 1rie:A, 1sqb:E, 1sqp:E, 1sqq:E, 1sqv:E, 1sqx:E, 7tay:E, 7tz6:E, 7tz6:R, 8ugd:3E, 8ugd:3R, 8uge:3E, 8uge:3R, 8ugf:3E, 8ugf:3R, 8ugg:3E, 8ugg:3R, 8ugh:3E, 8ugh:3R, 8ugi:3E, 8ugi:3R, 8ugj:3E, 8ugj:3R, 8ugk:3E, 8ugk:3R, 8ugn:3E, 8ugn:3R, 8ugr:3E, 8ugr:3R, 8ugr:6E, 8ugr:6R, 5xte:C, 5xte:P, 5xth:AC, 5xth:AP, 5xti:AC, 5xti:AP, 6xvf:E, 2ybb:e, 2ybb:E, 6zfs:E, 6zft:E, 6zfu:E
34 8cnt:A 620 28 0.3077 0.0194 0.4286 2.4
35 8sor:A 1156 15 0.2308 0.0078 0.6000 3.6
36 3wp6:A 228 24 0.3077 0.0526 0.5000 3.7
37 8sg2:A 163 40 0.3077 0.0736 0.3000 4.9 6dun:A, 6dun:B, 7efj:A, 7efx:A, 7ekv:A, 7f0m:A, 7f0m:C, 7f0m:B, 7f0m:D, 1f8a:B, 4gwv:A, 3i6c:A, 3i6c:B, 1i8g:B, 1i8h:B, 3ikd:A, 3ikd:B, 3ikg:A, 3ikg:B, 9inr:A, 9inr:B, 2itk:A, 3jyj:A, 3jyj:B, 3kab:A, 3kac:A, 3kac:B, 3kad:A, 3kaf:A, 3kag:A, 3kah:A, 3kai:A, 3kce:A, 2lb3:A, 2n1o:A, 1nmw:A, 3ntp:A, 6o33:A, 6o34:A, 3odk:A, 3oob:A, 1pin:A, 2q5a:A, 3tc5:A, 3tcz:A, 3tdb:A, 4tns:A, 4tyo:A, 4tyo:B, 5uy9:A, 6vaj:A, 3wh0:A, 2xp3:A, 2xp4:A, 2xp5:A, 2xp6:A, 2xp7:A, 2xp8:A, 2xp9:A, 2xpa:A, 2xpb:A
38 5d0u:A 705 27 0.2821 0.0156 0.4074 5.1 5lta:A, 5ltj:A, 5ltk:A, 6qid:A, 6qie:A
39 2xwp:A 257 13 0.1795 0.0272 0.5385 5.5
40 3vkg:A 2954 39 0.3077 0.0041 0.3077 5.7
41 3vkg:B 2853 39 0.3077 0.0042 0.3077 6.0
42 3vkh:B 2908 39 0.3077 0.0041 0.3077 6.0
43 3vkh:A 3042 39 0.3077 0.0039 0.3077 6.5
44 8ssz:B 384 25 0.2308 0.0234 0.3600 7.4 6cnj:B, 6cnj:C, 6cnj:E, 6cnk:C, 6cnk:E, 5kxi:B, 5kxi:E, 8st0:B, 8st2:C, 8st2:E, 8st3:B, 8st3:E, 8st4:B, 8st4:E, 6ur8:B, 6usf:E
45 3vol:A 138 16 0.2051 0.0580 0.5000 7.6 4hi4:A, 4hi4:B, 4hi4:D, 4hi4:G
46 7qix:G 261 25 0.2564 0.0383 0.4000 7.7 7qiz:w
47 4bts:AW 259 17 0.2051 0.0309 0.4706 8.3 4bts:BW, 4bts:CW, 4bts:DW, 5jpq:p, 4v5o:AW, 4v5o:BW
48 8jiw:BE 263 25 0.2564 0.0380 0.4000 8.9 8auv:A, 8b2l:A1, 8ip8:ja, 8ip9:ja, 8ipa:ja, 8ipb:ja, 8r6f:E, 4v3p:SD, 4v7e:BE
49 2fue:A 246 14 0.1538 0.0244 0.4286 9.4 6cfr:A, 6cfs:A, 6cft:A, 6cfu:A, 6cfv:A, 2fuc:A
50 6zj3:SE 265 21 0.2308 0.0340 0.4286 9.4
51 5ydl:A 408 25 0.2051 0.0196 0.3200 10.0 5ydm:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218