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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NASIYQEFVNKYSLSKTLRFELIPQGKTLENIKARGLILDDEKRAKDYKKAKQIIDKYHQFFIEEILSSVCISEDLLQNY
SDVYFKLKKSDDDNLQKDFKSAKDTIKKQISEYIKDSEKFKNLFNQNLIDAKKSDLILWLKQSKDNGIELFKANSDITDI
DEALEIIKSFKGWTTYFKGFHENRKNVYSSNDIPTSIIYRIVDDNLPKFLENKAKYESLKDKAPEAINYEQIKKDLAEEL
TFDIDYKTSEVNQRVFSLDEVFEIANFNNYLNQSGITKFNTIIGGKFVNGENTKRKGINEYINLYSQQINDKTLKKYKMS
VLFKQILSDTESKSFVIDKLEDDSDVVTTMQSFYEQIAAFKTVEEKSIKETLSLLFDDLKAQKLDLSKIYFKNDKSLTDL
SQQVFDDYSVIGTAVLEYITQKTEKAKYLSLETIKLALEEFNKHRDIDKQCRFEEILANFAAIPMIFDEIAQNKDNLAQI
SIKYQNQGKKDLLQASAEDDVKAIKDLLDQTNNLLHKLKIFHISQSEDKANILDKDEHFYLVFEECYFELANIVPLYNKI
RNYITQKPYSDEKFKLNFENSTLANGWDKNKEPDNTAILFIKDDKYYLGVMNKKNNKIFDDKAIKENKGEGYKKIVYKLL
PGANKMLPKVFFSAKSIKFYNPSEDILRIRNHSTHTKNGSPQKGYEKFEFNIEDCRKFIDFYKQSISKHPEWKDFGFRFS
DTQRYNSIDEFYREVENQGYKLTFENISESYIDSVVNQGKLYLFQIYNKDFSAYSKGRPNLHTLYWKALFDERNLQDVVY
KLNGEAELFYRKQSIPKKITHPAKEAIANKNKDNPKKESVFEYDLIKDKRFTEDKFFFHCPITINFKSSGANKFNDEINL
LLKEKANDVHILSIDRGERHLAYYTLVDGKGNIIKQDTFNIIGNDRMKTNYHDKLAAIEKDRDSARKDWKKINNIKEMKE
GYLSQVVHEIAKLVIEYNAIVVFQDLKVEKQVYQKLEKMLIEKLNYLVFKDNEFDKTGGVLRAYQLTAPFETFKKMGKQT
GIIYYVPAGFTSKICPVTGFVNQLYPKYESVSKSQEFFSKFDKICYNLDKGYFEFSFDYKNFGDKAAKGKWTIASFGSRL
INFRNDTREVYPTKELEKLLKDYSIEYGHGECIKAAICGESDKKFFAKLTSVLNTILQMANSKTDYLISPVADVNGNFFD
SRQAPKNMPQDADANGAYHIGLKGLMLLGRIKNNQEGKKLNLVIKNEEYFEFVQNRNN

The query sequence (length=1258) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6gtg:A 1298 1298 0.9968 0.9661 0.9661 0.0 6gtc:A, 6gte:A, 6gtf:A, 6i1k:A, 6i1l:A
2 6gtd:A 1269 1277 0.9889 0.9803 0.9742 0.0 6i1l:D, 5nfv:A, 5ng6:A, 5ng6:C, 5ng6:E, 5ng6:G
3 5mga:A 1182 1262 0.9229 0.9822 0.9200 0.0
4 6iv6:A 1209 1304 0.4086 0.4251 0.3942 0.0
5 5xut:A 1217 1300 0.4134 0.4273 0.4000 0.0 5id6:A, 6nm9:B, 6nm9:D, 6nma:B, 6nmc:A, 6nmd:A, 6nme:A, 6omv:B, 5xus:A, 5xuu:A, 5xuz:A, 5xuz:E
6 8i54:A 1113 1286 0.4014 0.4537 0.3927 0.0
7 8h9d:A 1114 1277 0.3990 0.4506 0.3931 0.0
8 6kl9:A 1180 1297 0.3998 0.4263 0.3878 0.0
9 8kgf:A 1261 1345 0.3935 0.3925 0.3680 0.0
10 8sfn:A 1302 1382 0.3736 0.3610 0.3401 0.0 8sfh:A, 8sfl:A, 5xh6:A, 5xh7:A
11 8sfo:A 1240 1348 0.3688 0.3742 0.3442 0.0 8sfi:A, 8sfp:A, 8sfq:A, 8sfr:A
12 5kk5:A 1201 1313 0.3688 0.3863 0.3534 0.0
13 5b43:A 1272 1359 0.3712 0.3671 0.3436 0.0
14 6klb:A 1118 551 0.2059 0.2317 0.4701 5.90e-145 6klb:D
15 6klb:A 1118 654 0.1614 0.1816 0.3104 5.02e-62 6klb:D
16 6p7m:A 1070 568 0.2083 0.2449 0.4613 5.69e-143 6p7n:A, 6p7n:E
17 6p7m:A 1070 643 0.1510 0.1776 0.2955 2.84e-52 6p7n:A, 6p7n:E
18 8sfj:A 1001 762 0.2218 0.2787 0.3661 6.57e-126
19 8sfj:A 1001 363 0.0946 0.1189 0.3278 5.95e-36
20 8d4a:A 1207 265 0.0485 0.0505 0.2302 8.25e-05 8d4b:A
21 8d4a:A 1207 53 0.0151 0.0157 0.3585 9.9 8d4b:A
22 7v94:A 1076 188 0.0350 0.0409 0.2340 0.067 7v93:A
23 5f0o:A 1018 67 0.0167 0.0206 0.3134 0.30
24 8d49:A 1072 72 0.0207 0.0243 0.3611 0.89
25 8d49:A 1072 77 0.0191 0.0224 0.3117 2.6
26 8d49:A 1072 50 0.0151 0.0177 0.3800 3.6
27 5gan:B 1781 117 0.0238 0.0168 0.2564 2.7 4bgd:A, 5gao:B, 5gap:B, 5nrl:B, 5zwm:D, 5zwo:D
28 6nd4:b 425 150 0.0238 0.0706 0.2000 4.5 5wlc:SB
29 4dxv:A 291 79 0.0159 0.0687 0.2532 6.4 3pue:B, 3pul:B, 3rk8:A, 3rk8:B, 3tak:A, 3tak:B, 3tce:A, 3tce:B, 3tdf:A, 3tdf:B, 3u8g:A, 3u8g:B
30 7aju:CE 436 165 0.0246 0.0711 0.1879 6.7 7ajt:CE, 7d4i:3E, 7d5s:3E, 7d5t:3E, 7d63:3E, 6ke6:3E, 6lqp:3E, 6lqq:3E, 6lqr:3E, 6lqs:3E, 6lqt:3E, 6lqu:3E, 6lqv:3E, 7suk:SB, 5wyj:3E, 5wyk:3E, 6zqa:CE, 6zqb:CE, 6zqc:CE, 6zqd:CE, 6zqe:CE
31 8adl:A 633 51 0.0143 0.0284 0.3529 7.9 8adl:I
32 2x65:A 334 55 0.0135 0.0509 0.3091 8.4 2x5z:A, 2x5z:B, 2x60:A, 2x60:B, 2x65:B
33 3d19:A 264 53 0.0135 0.0644 0.3208 8.9 3d19:B, 3d19:C, 3d19:D, 3d19:E, 3d19:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218