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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTSISENGTIMNLQYYKGAFVIMSGFIDTETSVG
YYNLEVISEQATAYVIKINELKELLSKNLTHFFYVFQTLQKQVSYSLAKFNDFSINGKLGSICGQLLILTYVYGKETPDG
IKITLDNLTMQELGYSAVSRIISKLKQEKVIVYKNSCFYVQNLDYLKRYAPKLDEWFYLACPATWGKLN

The query sequence (length=229) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5lej:B 237 236 1.0000 0.9662 0.9703 4.73e-168 2beo:A, 8cb4:A, 8cb4:B, 8cb5:A, 8cb5:B, 8cb7:A, 8cb7:B, 8cb8:B, 8cb8:A, 8cbg:A, 8cbg:B, 8cbi:B, 8cbi:A, 6eut:A, 6eut:B, 6euu:B, 6euz:A, 6euz:B, 6ev0:A, 6ev0:B, 6exk:A, 6exk:B, 6exl:A, 6exl:B, 6exm:A, 6exm:B, 5f1r:A, 5f1r:B, 6hck:A, 5lej:A, 5lek:A, 5lek:B, 5lrr:A, 5lrr:B, 5lrr:C, 5lrr:D, 5lrr:E, 5lrr:F, 5lrr:G, 5lrr:H, 5lrs:A, 5lrs:B, 6qwf:A, 6qwf:B, 6qwh:A, 6qwh:B, 6qwk:A, 6qwk:B, 6qwm:A, 6qwm:B, 6t5i:A, 5x6d:A, 5x6d:B, 5x6d:H, 5x6d:G, 5x6d:M, 5x6d:N, 5x6e:M, 5x6e:N, 5x6e:B, 5x6e:A, 5x6e:E, 5x6e:F
2 8cbp:A 212 229 0.9258 1.0000 0.9258 3.24e-151
3 2xhk:B 217 201 0.2052 0.2166 0.2338 0.001 2xgx:A, 2xgx:B, 2xhk:A, 2xko:A, 2xko:B, 2xkp:A, 2xkp:B, 2xkp:C, 2xkp:D, 2xkp:E, 2xkp:F
4 2h6b:A 239 217 0.2140 0.2050 0.2258 0.24 3e5u:C, 3e5u:D, 3e5u:A, 3e5u:B, 3e5x:A, 3e5x:B, 3e5x:C, 3e5x:D, 3e6b:A, 3e6b:B, 3e6c:C, 2h6b:B
5 7cv9:A 356 52 0.0568 0.0365 0.2500 0.46 7cv6:B, 7cv7:A, 7cv7:B
6 7cv9:C 351 52 0.0568 0.0370 0.2500 0.47 7cv8:A, 7dpe:A
7 8txz:A 858 33 0.0349 0.0093 0.2424 1.8
8 8tzg:A 906 33 0.0349 0.0088 0.2424 1.8
9 3ayi:A 684 45 0.0611 0.0205 0.3111 2.8 3ayi:B, 3ayj:A, 3ayj:B, 3ayl:A, 3ayl:B, 2yr5:A, 2yr5:B, 2yr6:A, 2yr6:B
10 2yr4:A 674 45 0.0611 0.0208 0.3111 2.9 2yr4:B
11 2au6:A 175 28 0.0437 0.0571 0.3571 3.3 2au7:A, 2au8:A, 2au9:A, 2auu:A, 1i40:A, 1i6t:A, 1ino:A, 1ipw:A, 1ipw:B, 1jfd:A, 1jfd:B, 1mjw:A, 1mjw:B, 1mjx:A, 1mjx:B, 1obw:A, 1obw:B, 1obw:C, 4um4:A, 4um4:B, 4um4:C
12 5d2l:F 238 48 0.0611 0.0588 0.2917 3.8 5d2l:J, 5d2l:P
13 8tzh:A 1485 30 0.0349 0.0054 0.2667 4.8 3d6t:B
14 5frb:A 470 40 0.0611 0.0298 0.3500 6.4 6cr2:A, 6cr2:B, 4uyl:A, 4uyl:B, 4uym:A, 4uym:B
15 6az1:X 152 39 0.0524 0.0789 0.3077 9.1 8a3w:SX, 8a98:SX, 8ovj:SX, 8rxh:SX, 8rxx:SX, 5t2a:AO
16 6hzn:A 743 32 0.0480 0.0148 0.3438 9.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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