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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNREARQAGQLLKEAGYTFDIAYTSVLKRAIRTLWHVQDQMDLMYVPVV
HSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTPPPALEPGDERAPYADPRYAKVPREQLPLTECLKDTVARVL
PLWNESIAPAVKAGKQVLIAAHGNSLRALIKYLDGISDADIVGLNIPNGVPLVYELDESLTPIRHYYLGD

The query sequence (length=230) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3gp5:A 248 230 1.0000 0.9274 1.0000 3.14e-173 3fdz:A, 3gp3:A, 3gp3:B, 3gp3:C, 3gp3:D, 3gp5:B, 3gw8:A, 3gw8:B
2 1e59:A 239 228 0.6522 0.6276 0.6579 5.22e-112
3 7xb8:B 249 232 0.6174 0.5703 0.6121 1.46e-97 6isn:C, 8it4:A, 8it4:B, 8it5:C, 8it6:C, 8it7:C, 8it8:C, 8itb:C, 8itc:C, 8itd:C, 7xb7:B, 7xb7:C, 7xb8:C, 7xb9:B, 7xb9:C, 5y2i:B, 5y2u:B, 5y2u:C, 5y35:C, 5y64:C, 5y65:C, 1yfk:A, 1yjx:B, 1yjx:C, 1yjx:D, 1yjx:E, 1yjx:G, 1yjx:I, 1yjx:J, 1yjx:K, 1yjx:L, 5zrm:C, 5zs8:C
4 2h4z:A 255 234 0.5304 0.4784 0.5214 1.41e-84 2f90:A, 2f90:B, 2h4z:B, 2hhj:A, 2hhj:B, 7n3r:B, 7n3s:A, 7n3s:B, 7thi:A, 7thi:B
5 1qhf:A 240 227 0.5217 0.5000 0.5286 7.28e-80 1bq3:D, 1bq3:A, 1bq4:A, 5pgm:E, 1qhf:B
6 4ij6:A 207 129 0.1783 0.1981 0.3178 7.51e-10 4ij6:B
7 1h2e:A 207 97 0.1522 0.1691 0.3608 2.86e-08 1h2f:A
8 5zr2:C 198 64 0.1174 0.1364 0.4219 5.94e-08 6m1x:C, 6m1x:D, 5zr2:A, 5zr2:B, 5zr2:D
9 1k6m:A 432 204 0.2087 0.1111 0.2353 1.82e-04 1c7z:A, 1c7z:B, 1c80:A, 1c80:B, 1c81:A, 1fbt:A, 1fbt:B, 1k6m:B, 1tip:A, 1tip:B
10 5htk:A 425 191 0.2174 0.1176 0.2618 0.005 5hr5:A, 5htk:B
11 1bif:A 432 190 0.1913 0.1019 0.2316 0.006 2bif:A, 2bif:B
12 3mbk:A 264 178 0.1739 0.1515 0.2247 0.007 3mbk:B, 8u5m:A, 8u5m:C, 8u5m:D, 8u7e:A, 8u7e:C, 8u7e:D
13 3lg2:A 269 48 0.0652 0.0558 0.3125 0.017 3lg2:B, 3lg2:C, 3lg2:D, 3ll4:A, 3ll4:B, 3oi7:A, 3oi7:B, 3oi7:C, 3oi7:D
14 2axn:A 451 205 0.2217 0.1131 0.2488 0.020 5ajv:B, 5ajw:A, 5ajx:A, 5ajy:A, 5ajz:A, 5ak0:A, 4d4j:A, 4d4k:A, 4d4l:A, 4d4m:A, 2dwo:A, 2dwp:A, 6etj:A, 6hvh:A, 6hvi:A, 6hvj:A, 2i1v:B, 6ibx:A, 6iby:A, 6ibz:A, 6ic0:A, 4ma4:A, 3qpu:A, 3qpv:A, 3qpw:A
15 1n63:B 805 33 0.0696 0.0199 0.4848 0.20 1n5w:B, 1n5w:E, 1n60:B, 1n60:E, 1n61:B, 1n61:E, 1n62:B, 1n62:E, 1n63:E, 1zxi:B, 1zxi:E
16 6b4o:A 451 100 0.1043 0.0532 0.2400 3.4 6b4o:B, 6b4o:C, 6b4o:D
17 3cew:A 118 19 0.0522 0.1017 0.6316 3.5 3cew:B, 3cew:C, 3cew:D
18 6rxt:CM 445 49 0.0652 0.0337 0.3061 4.1 5oql:d, 6rxu:CM, 6rxv:CM, 6rxx:CM, 6rxy:CM, 6rxz:CM
19 3juk:A 265 59 0.0696 0.0604 0.2712 4.3 3juk:B, 3juk:C, 3juk:D
20 4gz7:A 492 55 0.0652 0.0305 0.2727 5.6 4h00:A, 4h01:A, 4lcq:A, 4lcr:A, 4lcs:A
21 1ffu:B 797 151 0.1609 0.0464 0.2450 6.6 1ffu:E, 1ffv:B, 1ffv:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218