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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MVTVAVPKERAPGERRVALVPEVVARLVKGGARVRVERGAGEGAYHPDEAYQEAGAEVVERGELLKGAHLLFTVQPPPED
LIQALEPGAIVVGFVQPHKNLELVRALQAKKATVIAMELIPRITRAQSMDALSSQATVAGYLAAIHAARLSPRFFPMLTT
AAGTIRPAKVMVMGVGVAGLMAIATAKRLGAQVFAYDVRKAALEQALSLGAKPIELPISAEGEGGYARELTEEEKRIQHE
ALRDHVAGMDVLITTAQVPGRRAPILLTEDMVERLKPGTVVVDLAAESGGNCVLTKPGEVVEVRGVRVYGPLNLPSELSV
HASEMYAKNLYNLSSLLIEKGAFAPKWEDEIVRAALLMKEGEVLHGPTKALLG

The query sequence (length=373) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4j1t:E 373 373 1.0000 1.0000 1.0000 0.0 4j16:A, 4j16:B, 4j1t:B, 4o9u:E, 4o9u:F
2 3p2y:A 345 359 0.4638 0.5014 0.4819 3.69e-102
3 1f8g:A 382 372 0.4665 0.4555 0.4677 4.93e-102 1f8g:B, 1f8g:C, 1f8g:D, 2frd:A, 2frd:B, 2fsv:A, 1hzz:A, 1l7e:A, 1l7e:D, 1nm5:A, 1nm5:B, 2oo5:A, 2oo5:B, 2oor:A, 2oor:B, 1ptj:A, 1u28:A, 1u28:B, 1u2d:A, 1u2d:B, 1u2g:A, 1xlt:A, 1xlt:B, 1xlt:D, 1xlt:E, 1xlt:H, 1xlt:G
4 1u2g:B 359 370 0.4424 0.4596 0.4459 1.44e-93 2fr8:A
5 2bru:B 364 363 0.4021 0.4121 0.4132 4.08e-87 1x14:B, 1x15:B
6 6qti:A 1038 384 0.4155 0.1493 0.4036 6.23e-80 1d4o:A, 1djl:A, 1djl:B, 1pt9:A, 1pt9:B, 6qti:B, 6que:A, 6que:B, 1u31:A, 1u31:B
7 8hye:C 371 322 0.2440 0.2453 0.2826 9.68e-23 8hye:A, 8hye:B
8 2vhw:E 373 338 0.2654 0.2654 0.2929 8.47e-21 4lmp:A, 6o7f:A, 2vhv:A, 2vhv:B, 2vhw:A, 2vhw:B, 2vhw:C, 2vhw:D, 2vhw:F, 2vhx:A, 2vhx:B, 2vhx:C, 2vhx:D, 2vhx:E, 2vhx:F, 2vhz:A, 2vhz:B, 2voj:A, 2voj:C, 2voj:E
9 1pjc:A 361 358 0.2815 0.2909 0.2933 2.67e-20 1say:A
10 8hyh:A 366 322 0.2252 0.2295 0.2609 5.75e-16
11 4cpd:A 346 72 0.0858 0.0925 0.4444 0.002 4cpd:B, 4cpd:C, 4cpd:D
12 2oui:A 360 46 0.0563 0.0583 0.4565 0.010 2oui:B, 2oui:C, 2oui:D, 1y9a:A, 1y9a:C
13 3fpc:A 352 46 0.0563 0.0597 0.4565 0.011 3fpc:B, 3fpc:C, 3fpc:D
14 2rir:E 298 128 0.0885 0.1107 0.2578 0.016 2rir:A, 2rir:B, 2rir:C, 2rir:D, 2rir:F, 2rir:G, 2rir:H
15 3qe3:A 351 106 0.0938 0.0997 0.3302 0.24
16 6sch:C 355 51 0.0563 0.0592 0.4118 0.24 2b83:A, 2b83:B, 2b83:C, 2b83:D, 1jqb:A, 1jqb:B, 1jqb:C, 1jqb:D, 1kev:A, 1kev:B, 1kev:C, 1kev:D, 1ped:A, 1ped:B, 1ped:C, 1ped:D, 6sch:A, 6sch:B, 6sch:D
17 4jbg:A 333 61 0.0670 0.0751 0.4098 0.96 4jbg:B, 4jbg:C, 4jbg:D, 4jbh:A, 4jbh:B, 4jbh:C, 4jbh:D, 4jbi:A, 4jbi:B, 4jbi:C, 4jbi:D, 4jbi:E, 4jbi:F, 4jbi:G, 4jbi:H, 4jbi:I, 4jbi:J, 4jbi:K, 4jbi:L, 4jbi:M, 4jbi:N, 4jbi:O, 4jbi:P
18 6z42:A 336 47 0.0536 0.0595 0.4255 1.2 6z42:B, 6z42:C, 6z42:D
19 5bqf:A 317 123 0.0804 0.0946 0.2439 1.2 5tsd:A, 5tsd:B, 4xcv:A
20 1pl6:A 356 75 0.0670 0.0702 0.3333 1.2 1pl6:B, 1pl6:C, 1pl6:D, 1pl7:A, 1pl7:B, 1pl7:C, 1pl7:D, 1pl8:A, 1pl8:B, 1pl8:C, 1pl8:D
21 1llu:A 341 48 0.0509 0.0557 0.3958 1.3 1llu:B, 1llu:C, 1llu:D, 1llu:E, 1llu:F, 1llu:G, 1llu:H
22 4a2c:A 346 44 0.0509 0.0549 0.4318 1.4 4a2c:B, 4uej:A, 4uej:B, 4uek:A, 4uek:B, 4ueo:A, 4ueo:B
23 6mh5:B 375 58 0.0509 0.0507 0.3276 1.4 6mh5:A
24 1rjw:A 339 52 0.0483 0.0531 0.3462 1.6 3pii:A, 3pii:C, 3pii:B, 3pii:D, 1rjw:B, 1rjw:C, 1rjw:D
25 2b4q:A 256 53 0.0536 0.0781 0.3774 1.8
26 5vm2:A 347 109 0.0858 0.0922 0.2936 2.3 5vm2:B
27 4j34:B 390 54 0.0483 0.0462 0.3333 2.3 4j2w:A, 4j2w:B, 4j31:A, 4j31:B, 4j33:A, 4j33:B, 4j34:A, 4j36:A, 4j36:B, 5x6r:A, 5x6r:B
28 5x7o:A 1247 42 0.0456 0.0136 0.4048 2.5 5x7o:B, 5x7p:B, 5x7p:A, 5x7q:A, 5x7q:B, 5x7r:A, 5x7r:B, 5x7s:A, 5x7s:B
29 4om8:A 309 41 0.0456 0.0550 0.4146 2.8 4om8:B
30 3gg2:A 431 48 0.0456 0.0394 0.3542 2.8 3gg2:D, 3gg2:B, 3gg2:C
31 5yeq:B 329 89 0.0697 0.0790 0.2921 2.9
32 7f3p:D 355 48 0.0536 0.0563 0.4167 3.0 1bxz:B, 1bxz:C, 7f3p:A, 7f3p:B, 7f3p:C, 2nvb:A, 2nvb:B, 2nvb:C, 2nvb:D, 6sdm:A, 6sdm:C, 6sdm:D, 7utc:A, 7utc:B, 7utc:C, 7utc:D, 7uut:A, 7uut:B, 7uut:C, 7uut:D, 7ux4:A, 7ux4:B, 7ux4:C, 7ux4:D, 7xy9:A, 7xy9:B, 7xy9:C, 7xy9:D, 1ykf:A, 1ykf:B, 1ykf:C, 1ykf:D
33 8p2f:E 670 48 0.0509 0.0284 0.3958 3.4 8p2g:E, 8p2h:E
34 3s2e:A 340 48 0.0483 0.0529 0.3750 3.4 3s1l:A, 3s1l:B, 3s1l:C, 3s1l:D, 3s2e:B, 3s2e:C, 3s2e:D, 3s2e:E, 3s2e:F, 3s2e:G, 3s2e:H, 3s2f:A, 3s2f:B, 3s2f:C, 3s2f:D, 3s2f:E, 3s2f:F, 3s2f:G, 3s2f:H, 3s2g:A, 3s2g:B, 3s2g:C, 3s2g:D, 3s2g:E, 3s2g:F, 3s2g:G, 3s2g:H, 3s2i:A, 3s2i:B, 3s2i:C, 3s2i:D, 3s2i:E, 3s2i:F, 3s2i:G, 3s2i:H
35 4a7z:A 881 42 0.0456 0.0193 0.4048 3.5 4a7k:A, 4a7y:A
36 3fpl:A 351 48 0.0536 0.0570 0.4167 3.6
37 6n7l:C 344 52 0.0536 0.0581 0.3846 3.8 6n7l:A, 6n7l:B, 6n7l:D, 6n7l:E, 6n7l:F, 6n7l:G, 6n7l:H, 6n7l:I, 6n7l:J, 6n7l:K, 6n7l:L
38 3two:B 348 66 0.0563 0.0603 0.3182 4.3 3two:A
39 2cd9:A 363 115 0.0670 0.0689 0.2174 4.6 2cd9:B, 2cda:A, 2cda:B, 2cdb:A, 2cdb:B, 2cdb:C, 2cdb:D, 2cdc:A, 2cdc:B, 2cdc:C, 2cdc:D
40 5kia:A 339 44 0.0456 0.0501 0.3864 4.6
41 7y9p:A 357 43 0.0483 0.0504 0.4186 4.7
42 3meq:A 341 42 0.0429 0.0469 0.3810 4.9 3meq:B, 3meq:C, 3meq:D
43 6v7b:a 126 122 0.0831 0.2460 0.2541 4.9 6v7b:b, 6v7b:c, 6v7b:d, 6v7b:e, 6v7b:f, 6v7b:g, 6v7b:h, 6v7b:i, 6v7b:j, 6v7b:k, 6v7b:l, 6v7b:m, 6v7b:n, 6v7b:o, 6v7b:p, 6v7b:q, 6v7b:r, 6v7b:s, 6v7b:t, 6v7b:u, 6v7b:v, 6v7b:w
44 3fsr:A 352 48 0.0509 0.0540 0.3958 5.1 3fsr:C, 3ftn:A, 3ftn:B, 3ftn:C, 3ftn:D
45 6hni:A 295 65 0.0563 0.0712 0.3231 5.9
46 2gmh:A 581 44 0.0483 0.0310 0.4091 6.8 2gmh:B, 2gmj:A, 2gmj:B
47 3v4l:A 386 133 0.0858 0.0829 0.2406 7.5 7a41:B, 6f7i:B, 6h4a:A, 4i1p:A, 4i1p:C, 7pav:B, 7paw:B, 3uo8:B, 3uo8:C, 3uoa:B, 3uoa:C, 3v4o:A, 8v4x:A, 8v4x:B, 8v4x:C, 8v4x:D, 8v4x:E, 8v4x:F, 6yn8:A, 6yn9:A
48 4il8:A 459 60 0.0456 0.0370 0.2833 7.6 3bkq:X, 3c04:A, 2fkf:A, 2fkm:X, 2h4l:X, 2h5a:X, 1k2y:X, 1k35:A, 4mrq:A, 1p5d:X, 1p5g:X, 1pcj:X, 1pcm:X, 3rsm:A
49 4z6k:A 345 43 0.0456 0.0493 0.3953 7.7 4z6k:B, 4z6k:C, 4z6k:D
50 4xr9:A 456 123 0.0912 0.0746 0.2764 8.1
51 7aau:C 378 138 0.0992 0.0979 0.2681 8.2 7aas:A, 7aas:B, 7aas:C, 7aas:D, 7aas:E, 7aas:F, 7aau:A, 7aau:B, 7aau:D, 7aau:E, 7aau:F, 7av7:A, 7av7:B, 7av7:C, 7av7:D, 7av7:E, 7av7:F
52 1dxy:A 330 28 0.0402 0.0455 0.5357 8.3
53 2eer:B 347 54 0.0590 0.0634 0.4074 8.3 2eer:A
54 5yyc:A 368 99 0.0777 0.0788 0.2929 8.4 5yyc:C
55 4zgs:A 346 35 0.0375 0.0405 0.4000 8.5 4zgs:B, 4zgs:C, 4zgs:D, 4zgs:E, 4zgs:F, 4zgs:G, 4zgs:H
56 6dkh:C 346 75 0.0590 0.0636 0.2933 9.0 6dkh:A, 6dkh:B, 6dkh:D
57 1qo8:A 564 37 0.0429 0.0284 0.4324 9.1 1qo8:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218