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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MVSSYFKGILLNLGLDEERIEVLENKGGIVEDEFEGMRYLRLKDSARSLRRGTVVFDEHNIILGFPHIKRVVQLENGIRR
AFKRKPFYVEEAVDGYNVRVAKIGEKILVFTRGGFVCPFTTERIEDFITLDFFKDYPNMVLCGEMAGPESPYLVEGPPYV
KEDIQFFLFDIQEKKTGRSLPVEERLKLAEEYGIPSVEVFGLYDLSRIDELHALIDRLTKEKREGIVMKSPDMKKIVKYV
TPYANINDIKIGARIFFDLPHGYFMQRIKRLAFYLAERKIRGEEFDEYARALGKVLLEPFVESIWDISSGDDEIAELFTV
RVKKLETAHKMVTHFERLRLKIHIDDIEVLDNGYWRITFKRVYPDATKEMRELWNGHAFVD

The query sequence (length=381) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ucf:A 381 381 0.9948 0.9948 0.9948 0.0 8uce:A, 8uce:B, 8ucg:A, 8ucg:B, 8uch:A, 8uci:A, 8uci:B
2 2vug:A 373 375 0.7008 0.7158 0.7120 0.0 2vug:B
3 3qwu:A 366 351 0.3412 0.3552 0.3704 4.55e-75 3qwu:B
4 5d1o:A 375 369 0.3307 0.3360 0.3415 2.34e-57 5d1o:B, 5d1p:A, 5d1p:B
5 6bkf:A 562 205 0.1207 0.0819 0.2244 0.11
6 7lsy:Y 855 212 0.1286 0.0573 0.2311 0.43 6bkg:A, 4htp:A, 4htp:B, 3w1b:A, 3w1g:A, 3w5o:A, 3w5o:B
7 6oa9:D 489 63 0.0630 0.0491 0.3810 0.51 6oaa:E, 6oab:E
8 6nsd:A 503 66 0.0551 0.0417 0.3182 0.69 6nsd:B
9 2afh:E 289 187 0.1024 0.1349 0.2086 2.6 2afh:F, 2afi:E, 2afi:F, 2afi:G, 2afi:H, 2afi:M, 2afi:N, 2afi:O, 2afi:P, 2c8v:A, 1de0:A, 1de0:B, 8dfc:E, 8dfc:F, 8dfd:E, 8dfd:F, 8dfd:G, 8dfd:H, 1fp6:A, 1fp6:B, 1fp6:C, 1fp6:D, 1g1m:A, 1g1m:B, 1g20:E, 1g20:F, 1g20:G, 1g20:H, 1g21:E, 1g21:F, 1g21:G, 1g21:H, 1g5p:A, 1g5p:B, 1m1y:E, 1m1y:F, 1m1y:G, 1m1y:H, 1m1y:M, 1m1y:N, 1m1y:O, 1m1y:P, 1m34:E, 1m34:F, 1m34:G, 1m34:H, 1m34:M, 1m34:N, 1m34:O, 1m34:P, 1n2c:E, 1n2c:F, 1n2c:G, 1n2c:H, 6n4j:A, 6n4j:B, 6n4k:A, 6n4k:B, 6n4l:A, 6n4m:A, 1nip:B, 1nip:A, 2nip:A, 2nip:B, 6o0b:A, 6o0b:B, 6q93:A, 6q93:B, 6q93:C, 6q93:D, 6q93:E, 6q93:F, 6q93:G, 6q93:H, 1rw4:A, 7t4h:A, 8tc3:A, 8tc3:B, 7tne:A, 7tpn:A, 7tpo:A, 7tpv:A, 7tpw:A, 7tpx:A, 7tpy:A, 7tpz:A, 7tq0:A, 7tq9:A, 7tqc:A, 7tqe:A, 7tqf:A, 7tqh:A, 7tqi:A, 7tqj:A, 7tqk:A, 7ut8:E, 7ut8:F, 7ut9:E, 7ut9:F, 7uta:E, 7uta:F, 7uta:G, 7uta:H, 4wza:E, 4wza:F, 4wza:G, 4wza:H, 4wzb:E, 4wzb:F, 4wzb:G, 4wzb:H, 1xcp:A, 1xcp:B, 1xcp:C, 1xcp:D, 1xd8:A, 1xd8:B, 1xd9:A, 1xd9:B, 1xdb:A, 1xdb:B
10 7us3:A 428 117 0.0840 0.0748 0.2735 3.4 7us3:B, 7us3:C, 7us3:D
11 1eu3:A 210 70 0.0499 0.0905 0.2714 6.1 1eu3:B
12 4h1z:B 388 94 0.0577 0.0567 0.2340 6.7 4h1z:A, 4h1z:C, 4h1z:D, 4h1z:E, 4h1z:F, 4h1z:G, 4h1z:H
13 3wq5:A 475 79 0.0420 0.0337 0.2025 9.8 3wq5:B, 3wq6:A, 3wq6:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218