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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MVRVKVNDRIVEVPPGTSVMDAVFHAGYDVPLFCSEKHLSPIGACRMCLVRIGLPIQWQPKLAASCVTAVADGMVVDTLS
DVVREAQAGMVEFTLLNHPLDCPTCDKGGACELQDRTVEYGLYEKYELPVYTRFEFTRRHVDKHHPLSPFVILDRERCIH
CKRCVRYFEEVPGDEVLDFIERGVHTFIGTMDFGLPSGFSGNITDICPVGALLDLTARFRARNWEMEETPTTCALCPVGC
GITADTRSGELLRIRAREVPEVNEIWICDAGRFGHEWADQNRLKTPLVRKEGRLVEATWEEAFLALKEGLKEARGEEVGL
YLAHDATLEEGLLASELAKALKTPHLDFQGRTAAPASLFPPASLEDLLQADFALVLGDPTEEAPILHLRLSEFVRDLKPP
HRYNHGTPFADLQIKERMPRRTDKMALFAPYRAPLMKWAAIHEVHRPGEEREILLALLGDKEGSEMVAKAKEAWEKAKNP
VLILGAGVLQDTVAAERARLLAERKGAKVLAMTPAANARGLEAMGVLPGAKGASWDEPGALYAYYGFVPPEEALKGKRFV
VMHLSHLHPLAERYAHVVLPAPTFYEKRGHLVNLEGRVLPLSPAPIENGEAEGALQVLALLAEALGVRPPFRLHLEAQKA
LKARKVPEAMGRLSFRLKELRPKERKGAFYLRPTMWKAHQAVGKAQEAARAELWAHPETARAEALPEGAQVAVETPFGRV
EARVVHREDVPKGHLYLSALGPAAGLRVEGRVLV

The query sequence (length=754) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4hea:3 756 756 1.0000 0.9974 0.9974 0.0 2fug:3, 2fug:C, 2fug:L, 2fug:U, 4hea:D, 6i0d:3, 6i0d:D, 6i1p:3, 6i1p:D, 3i9v:3, 3i9v:C, 3iam:3, 3iam:C, 3ias:3, 3ias:C, 3ias:L, 3ias:U, 3m9s:3, 3m9s:C, 6q8o:3, 6q8o:D, 6q8w:3, 6q8w:D, 6q8x:3, 6q8x:D, 6y11:3, 6y11:D, 2ybb:3, 6ziy:3, 6zjl:3, 6zjn:3, 6zjy:3
2 7arc:G 682 661 0.2719 0.3006 0.3101 4.42e-77 7ard:G
3 8e9h:G 782 677 0.2918 0.2813 0.3250 1.18e-74 8e9g:G, 8e9i:G
4 8esz:S1 683 727 0.2997 0.3309 0.3109 2.00e-72 8b9z:G, 8ba0:G, 8esw:S1
5 7b0n:G 694 675 0.2546 0.2767 0.2844 3.44e-71 6gcs:A, 7o6y:A, 7o71:A, 6rfq:A, 6rfr:A, 6rfs:A, 6y79:A, 6yj4:G
6 7a23:C 693 669 0.2560 0.2785 0.2885 4.45e-70 7a24:C, 7aqr:G, 7ar7:G, 7ar8:G, 7arb:G, 8bed:G, 8bpx:G, 8bq5:G, 8bq6:G
7 7qso:G 700 648 0.2586 0.2786 0.3009 2.13e-68 7ak5:G, 7ak6:G, 7b93:G, 8c2s:G, 8ca3:G, 8ca4:G, 8ca5:G, 7dgq:A, 7dgr:A, 7dgs:A, 7dgz:A, 7dh0:A, 7dkf:A2, 6g2j:G, 6g72:G, 5gpn:Y, 5gup:G, 8iao:G, 8iap:G, 8ib4:G, 8ib5:G, 8ib9:G, 8iba:G, 8ibd:G, 8ibe:G, 8ic2:G, 8ic3:G, 5lnk:3, 5o31:G, 8olt:G, 8om1:G, 7psa:G, 8pw5:3, 8pw6:3, 8pw7:3, 8q0a:G, 8q0f:G, 8q0j:G, 8q0m:G, 8q0o:G, 8q0q:G, 8q1p:G, 8q1u:G, 8q1y:G, 8q25:G, 8q45:G, 8q46:G, 8q47:G, 8q48:G, 8q49:G, 8q4a:G, 6q9d:S1, 6qa9:S1, 6qbx:S1, 6qc2:S1, 6qc3:S1, 6qc4:S1, 6qc5:S1, 6qc6:S1, 6qc7:S1, 6qc8:S1, 6qc9:S1, 6qca:S1, 6qcf:S1, 7qsd:G, 7qsk:G, 7qsl:G, 7qsm:G, 7qsn:G, 7r41:G, 7r42:G, 7r43:G, 7r44:G, 7r45:G, 7r46:G, 7r47:G, 7r48:G, 7r4c:G, 7r4d:G, 7r4f:G, 7r4g:G, 8rgp:3, 8rgq:3, 8rgr:3, 8rgt:3, 8ud1:1G, 8ueo:1G, 8uep:1G, 8ueq:1G, 8uer:1G, 8ues:1G, 8uet:1G, 8ueu:1G, 8uev:1G, 8uew:1G, 8uex:1G, 8uey:1G, 8uez:1G, 8ugh:1G, 8ugi:1G, 8ugj:1G, 8ugn:1G, 8ugn:5G, 8ugr:1G, 8ugr:5G, 7v2c:M, 7v2d:M, 7v2e:M, 7v2f:M, 7v2h:M, 7v2k:M, 7v2r:M, 7v30:M, 7v31:M, 7v32:M, 7v33:M, 7v3m:M, 7vb7:M, 7vbn:M, 7vbz:M, 7vwj:M, 7vxp:M, 7vxu:M, 7vy8:M, 7vya:M, 7vyf:M, 7vyh:M, 7vyn:M, 7vz1:M, 7vzv:M, 7vzw:M, 7w00:M, 7w0h:M, 7w0r:M, 7w0y:M, 7w1o:M, 7w1p:M, 7w1t:M, 7w1u:M, 7w1v:M, 7w1z:M, 7w20:M, 7w2k:M, 7w2l:M, 7w2r:M, 7w2u:M, 7w2y:M, 7w31:M, 7w32:M, 7w35:M, 7w4c:M, 7w4d:M, 7w4e:M, 7w4f:M, 7w4g:M, 7w4j:M, 7w4k:M, 7w4l:M, 7w4m:M, 7w4n:M, 7w4q:M, 5xtb:M, 5xtd:M, 5xth:M, 5xti:M, 5xti:BM, 7zd6:3, 7zdh:3, 7zdj:3, 7zdm:3, 7zdp:3, 7zeb:3, 6zk9:3, 6zkc:3, 6zkd:3, 6zke:3, 6zkf:3, 6zkg:3, 6zkh:3, 6zki:3, 6zkj:3, 6zkk:3, 6zkl:3, 6zkm:3, 6zkn:3, 6zko:3, 6zkp:3, 6zkq:3, 6zkr:3, 6zks:3, 6zkt:3, 6zku:3, 6zkv:3, 6zr2:G, 6ztq:G
8 7zm7:A 711 657 0.2586 0.2743 0.2968 7.35e-68 7zmb:A, 7zmg:A
9 6x89:S1 688 663 0.2586 0.2834 0.2941 2.09e-67 8e73:S1
10 8qby:G 666 646 0.2533 0.2868 0.2957 3.36e-66
11 8gym:s1 689 719 0.2653 0.2903 0.2782 6.78e-66 8b6f:AB, 8bqs:AB, 8gym:S1, 8gzu:s1, 8gzu:S1, 7tgh:S1
12 7awt:G 907 657 0.2401 0.1996 0.2755 9.65e-56 7nyr:G, 7nyu:G, 7nyv:G, 7nz1:G, 7p61:G, 7p62:G, 7p63:G, 7p64:G, 7p69:G, 7p7c:G, 7p7e:G, 7p7j:G, 7p7k:G, 7p7l:G, 7p7m:G, 7z7r:G, 7z7s:G, 7z7t:G, 7z7v:G, 7z80:G, 7z83:G, 7z84:G, 7zc5:G, 7zci:G
13 7t30:A 666 676 0.2401 0.2718 0.2678 1.76e-49 7t2r:A, 7t2r:F, 7t30:F
14 7q5y:A 626 301 0.1353 0.1629 0.3389 8.50e-40 7q5y:G, 7q5y:M, 7q5y:S
15 6tg9:A 949 433 0.1751 0.1391 0.3048 5.39e-39 6tg9:E, 6tga:A, 6tga:E
16 6tg9:A 949 76 0.0385 0.0306 0.3816 0.19 6tg9:E, 6tga:A, 6tga:E
17 5lc5:G 685 213 0.1127 0.1241 0.3991 1.72e-37 5ldw:G, 5ldx:G
18 8iuf:1A 352 277 0.1061 0.2273 0.2888 8.28e-29 8j9h:1A, 8j9i:1A, 8j9j:1A
19 8oh5:C 1172 515 0.1751 0.1126 0.2563 1.90e-28 8oh5:F, 8oh5:I, 8oh5:L, 8oh9:C, 8oh9:F, 8oh9:I, 8oh9:L
20 8oh5:C 1172 105 0.0398 0.0256 0.2857 1.38e-08 8oh5:F, 8oh5:I, 8oh5:L, 8oh9:C, 8oh9:F, 8oh9:I, 8oh9:L
21 8a6t:A 571 224 0.1008 0.1331 0.3393 3.46e-25 8a6t:D, 8bew:A, 8bew:D
22 8a5e:A 583 217 0.0995 0.1286 0.3456 1.64e-23 8a5e:D, 7q4v:A, 7q4v:E, 7q4w:A, 7q4w:E
23 7vw6:A 913 481 0.1565 0.1292 0.2453 3.65e-22 7e5z:A, 8j83:A, 7xqw:A
24 7vw6:A 913 52 0.0252 0.0208 0.3654 7.5 7e5z:A, 8j83:A, 7xqw:A
25 7p8n:a 642 202 0.0862 0.1012 0.3218 6.39e-22 7p5h:A, 7p5h:D, 7p5h:a, 7p5h:d, 7p8n:A, 7p91:a, 7p91:A, 7p92:A
26 5xf9:B 234 218 0.0822 0.2650 0.2844 5.61e-16 5xf9:F, 5xfa:B, 5xfa:F
27 1ogy:A 789 184 0.0782 0.0748 0.3207 5.60e-12 1ogy:C, 1ogy:E, 1ogy:G, 1ogy:I, 1ogy:K, 1ogy:M, 1ogy:O
28 7qv7:S 571 136 0.0504 0.0665 0.2794 7.99e-12 7qv7:Y
29 7qv7:S 571 102 0.0424 0.0560 0.3137 0.019 7qv7:Y
30 7bkb:D 549 476 0.1326 0.1821 0.2101 2.23e-11 7bkb:d, 7bkc:D, 7bkc:d, 7bkd:D, 7bke:D
31 2nya:A 791 184 0.0690 0.0657 0.2826 5.65e-10 2nya:F
32 4xdd:A 582 228 0.0690 0.0893 0.2281 3.20e-09 8aio:A, 8aio:B, 8aj6:A, 8aj6:B, 8aln:A, 8aln:B, 8ap2:A, 8ap2:B, 5byq:A, 5byq:B, 5byr:A, 5byr:B, 5bys:A, 5bys:B, 1c4a:A, 1c4c:A, 3c8y:A, 8cjy:A, 8cjy:B, 1feh:A, 6gly:A, 6gly:B, 6glz:A, 6glz:B, 6gm0:A, 6gm0:B, 6gm1:A, 6gm1:B, 6gm2:A, 6gm2:B, 6gm3:A, 6gm3:B, 6gm4:A, 6gm4:B, 6gm8:A, 6gm8:B, 6h63:A, 6h63:B, 5la3:A, 5la3:B, 6n59:A, 6n6p:A, 6nac:A, 5oef:A, 5oef:B, 8pvm:A, 8pvm:B, 7qhf:A, 7qhf:B, 8qm3:A, 8qm3:B, 4xdc:A, 4xdc:B, 4xdd:B, 6yf4:A, 6yf4:B
33 3ml1:A 799 184 0.0703 0.0663 0.2880 4.70e-09 3o5a:A
34 6h8k:A 628 138 0.0544 0.0653 0.2971 2.98e-08
35 1fdi:A 715 93 0.0358 0.0378 0.2903 4.41e-05 1aa6:A, 1fdo:A, 2iv2:X, 7z0t:A
36 1kqf:A 982 211 0.0663 0.0509 0.2370 4.14e-04 1kqg:A
37 1frr:A 95 42 0.0225 0.1789 0.4048 0.001 1frr:B
38 1h0h:A 977 241 0.0716 0.0553 0.2241 0.032 1h0h:K
39 2vpw:A 734 110 0.0398 0.0409 0.2727 0.053 2vpw:E, 2vpx:A, 2vpx:E, 2vpy:A, 2vpy:E, 2vpz:A, 2vpz:E
40 1czp:A 98 38 0.0186 0.1429 0.3684 0.49 1czp:B, 1ewy:C, 1fxa:A, 1fxa:B, 1j7a:A, 1j7b:A, 1j7c:A, 1qoa:A, 1qoa:B, 1qob:A, 1qob:B, 1qof:A, 1qof:B, 1qog:A, 1qog:B, 1qt9:A
41 1rfk:B 97 41 0.0186 0.1443 0.3415 0.89 3p63:A, 3p63:B, 1rfk:A
42 7akt:A 107 46 0.0186 0.1308 0.3043 1.2 6kum:A, 6kum:B, 6kv0:A, 6kv0:B, 6lk1:A, 6lk1:B, 2mh7:A, 2n0s:B, 7wzn:G
43 2e7z:A 727 40 0.0199 0.0206 0.3750 1.4
44 5t5i:J 431 82 0.0332 0.0580 0.3049 1.8 5t5i:B, 5t5m:B, 5t61:B, 5t61:H, 5t61:N, 5t61:T, 5t61:Z, 5t61:f, 5t61:l, 5t61:r
45 3ou8:B 314 68 0.0239 0.0573 0.2647 2.0 3ou8:A, 3pan:A, 3pan:B, 3pao:A, 3pao:B, 3pbm:A, 3pbm:B
46 5chc:A 895 51 0.0265 0.0223 0.3922 2.2 5ch7:A, 5ch7:C, 5ch7:E, 5chc:C, 5chc:E, 5e7o:A, 5e7o:C, 5e7o:E, 5e7o:G, 5e7o:I, 5e7o:K, 4ydd:A, 4ydd:C, 4ydd:E
47 1awd:A 94 45 0.0186 0.1489 0.3111 2.3
48 6jgz:B 3485 160 0.0477 0.0103 0.2250 2.8 6jg3:A, 6jg3:B, 6jg3:C, 6jg3:D, 6jgz:D, 6jgz:F, 6jgz:H, 6jh6:B, 6jh6:D, 6jh6:F, 6jh6:H, 6jhn:A, 6jhn:C, 6jhn:E, 6jhn:G, 6ji0:A, 6ji0:C, 6ji0:E, 6ji0:G, 6jrr:A, 6jrr:C, 6jrr:E, 6jrr:G
49 5go9:A 3423 160 0.0477 0.0105 0.2250 3.0 5go9:B, 5go9:C, 5go9:D, 5goa:A, 5goa:B, 5goa:C, 5goa:D
50 6jrs:A 3488 160 0.0477 0.0103 0.2250 3.0 6jrs:D, 6jrs:G, 6jrs:J
51 8cm5:A 974 119 0.0371 0.0287 0.2353 3.6 8bqg:A, 8bqh:A, 8bqi:A, 8bqj:A, 8bqk:A, 8bql:A, 8cm4:A, 8cm4:C, 8cm5:C, 8cm5:K, 8cm5:R, 8cm6:A, 8cm6:C, 8cm7:A, 8rc8:A, 8rc9:A, 8rca:A, 8rcb:A, 8rcc:A, 8rcg:A, 6sdr:A, 6sdv:A, 7z5o:AAA
52 6q6i:A 749 49 0.0239 0.0240 0.3673 3.9
53 7t2r:B 425 105 0.0332 0.0588 0.2381 5.6 7t2r:G, 7t30:B, 7t30:G
54 3b2g:A 98 42 0.0186 0.1429 0.3333 6.5 3b2g:B
55 7mgq:A 602 84 0.0345 0.0432 0.3095 6.9 7mgq:B, 7mgq:C, 7mgq:D
56 8jmr:A 171 57 0.0239 0.1053 0.3158 8.5
57 6jiy:A 3521 123 0.0385 0.0082 0.2358 9.5 6ji8:A, 6ji8:D, 6ji8:G, 6ji8:J, 6jii:B, 6jii:E, 6jii:H, 6jii:K, 6jiu:A, 6jiu:D, 6jiu:G, 6jiu:J, 6jiy:D, 6jiy:G, 6jiy:J, 6jv2:A, 6jv2:C, 6jv2:E, 6jv2:G
58 4uwq:A 548 127 0.0504 0.0693 0.2992 9.5 4uwq:D, 4uwq:G, 4uwq:J, 2wdc:A, 2wdd:A, 2wde:A, 2wdf:A
59 7os0:A 1130 85 0.0371 0.0248 0.3294 9.8 7os0:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218