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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEM
TPSLARLLLGKGRSLLLPAKWYSIPQCWRYERRREHYQWNMDIVGVKSVSAEVELVCAACWAMRSLGLSSKDVGIKVNSR
KVLQTVVEQAGTSDKFAPVCVIVDKMPREEVEAQLAVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYG
DWVLFDASVVRGLAYYTGIVFEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKRLLPDIPHV
VDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLRGFAVPLD
RLV

The query sequence (length=403) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4yrc:A 419 418 1.0000 0.9618 0.9641 0.0 3hrk:A, 3hrk:B, 3lc0:A, 4yp0:A, 4ypf:A, 4yre:A, 4yre:B, 4yrf:A, 4yrg:A, 4yri:A, 4yrj:A, 4yrk:A, 4yrk:B, 4yrl:A, 4yrm:A, 4yrm:B, 4yrn:A, 4yrn:B, 4yro:A, 4yrp:A, 4yrp:B, 4yrq:A, 4yrr:A, 4yrr:B, 4yrs:A, 4yrt:A
2 4phc:A 444 418 0.2680 0.2432 0.2584 6.07e-34 4phc:B, 4phc:C, 4phc:D
3 4e51:A 415 428 0.2953 0.2867 0.2780 1.94e-21 4e51:B
4 5e3i:B 398 415 0.2481 0.2513 0.2410 1.88e-17 5e3i:A
5 1adj:A 420 416 0.2605 0.2500 0.2524 2.85e-17 1adj:B, 1adj:C, 1adj:D, 1ady:A, 1ady:B, 1ady:C, 1ady:D, 4rdx:A
6 1kmm:C 387 409 0.2457 0.2558 0.2421 5.85e-17 2el9:A, 2el9:B, 2el9:C, 2el9:D, 1kmm:A, 1kmn:A, 1kmn:C
7 1htt:A 366 400 0.2258 0.2486 0.2275 2.29e-16 1htt:B, 1htt:C, 1htt:D, 1kmm:B, 1kmm:D, 1kmn:B, 1kmn:D
8 1z7m:B 318 269 0.1489 0.1887 0.2230 3.73e-09 1z7m:D
9 6ftt:A 379 338 0.1935 0.2058 0.2308 2.46e-07 6ftt:C, 6ftt:B, 6ftt:D, 6fu7:B, 6r02:A, 6r02:B, 6r02:C, 6r02:D
10 4cs3:A 270 84 0.0670 0.1000 0.3214 0.006 6aac:A, 6aad:A, 6aan:A, 6aao:A, 6aap:A, 6aaq:A, 6aaz:A, 6ab0:A, 6ab1:A, 6ab2:A, 6ab8:A, 6abk:A, 6abl:A, 6abm:A, 4bw9:A, 4bwa:A, 4ch3:A, 4ch4:A, 4ch5:A, 4ch6:A, 4cs4:A, 5k1p:A, 5k1x:A, 8ke1:A, 8ke2:A, 8ke3:A, 8ke4:A, 8ke5:A, 8ke6:A, 6ly3:A, 6ly6:A, 6ly7:A, 6lya:A, 6lyb:A, 4q6g:A, 2q7e:A, 2q7g:A, 2q7h:A, 3qtc:A, 7rsm:A, 7rsm:B, 7rsm:C, 7rsm:D, 4tqd:A, 4tqf:A, 3vqv:A, 3vqw:A, 3vqx:A, 3vqx:B, 3vqx:C, 3vqx:D, 3vqy:A, 2zce:A, 2zim:A, 2zin:A, 2zio:A, 4zib:A
11 3vkh:A 3042 141 0.0769 0.0102 0.2199 4.0
12 3vkg:B 2853 141 0.0769 0.0109 0.2199 4.1
13 3vkg:A 2954 141 0.0769 0.0105 0.2199 4.2
14 3vkh:B 2908 141 0.0769 0.0107 0.2199 4.3
15 3ej2:A 182 40 0.0347 0.0769 0.3500 5.2 3eiy:A, 3ej0:A
16 6edz:C 723 81 0.0645 0.0360 0.3210 5.5
17 6edw:B 746 81 0.0645 0.0349 0.3210 5.8 6edw:A, 6edw:D, 6edz:A, 6edz:B, 6edz:D, 6ee1:B, 6ee1:D
18 6edw:C 724 81 0.0645 0.0359 0.3210 6.0 6ee1:A, 6ee1:C
19 7t3p:A 2066 68 0.0447 0.0087 0.2647 6.0 7t3p:B, 7t3p:C, 7t3p:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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