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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MTVLDREQVLSAFKNRKSCRHYDAARKISAEDFQFILELGRLSPSSVGSEPWQFVVVQNPEIRQAIKPFSWGMADALDTA
SHLVVFLAKKNARFDSPFMLESLKRRGVTEPDAMAKSLARYQAFQADDIKILDDSRALFDWCCRQTYIALGNMMTGAAMA
GIDSCPVEGFNYADMERVLSGQFGLFDAAEWGVSVAATFGYRVQEIATKARRPLEETVIWA

The query sequence (length=221) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6wt2:A 221 221 1.0000 1.0000 1.0000 4.64e-167 6wt2:B, 6wt2:C, 6wt2:D
2 7s14:B 223 220 0.5882 0.5830 0.5909 1.68e-95 7ldq:A, 7rzl:A, 7rzl:B, 7rzp:A, 7rzp:B, 7s14:A, 7s14:C, 7s14:D, 7s1a:A, 7s1a:B, 7t2z:A, 7t2z:B, 7t33:A, 7t33:B
3 8qyg:B 225 217 0.4299 0.4222 0.4378 1.88e-68 8q5g:A, 8q5g:B, 8qyg:A
4 2hay:D 222 214 0.4208 0.4189 0.4346 1.51e-62 2hay:A, 2hay:B, 2hay:C
5 7jh4:A 223 216 0.4299 0.4260 0.4398 2.43e-62 7jh4:B, 7jh4:C, 7jh4:D, 7jh4:E
6 2h0u:A 196 207 0.3665 0.4133 0.3913 3.49e-42
7 5j8d:A 216 221 0.2851 0.2917 0.2851 3.54e-19 5j8d:B, 5j8d:C, 5j8d:D, 5j8g:A, 5j8g:B, 5j8g:C, 5j8g:D, 1kqb:A, 1kqb:B, 1kqb:C, 1kqb:D, 1kqc:A, 1kqc:B, 1kqc:C, 1kqc:D, 1kqd:A, 1kqd:B, 1kqd:C, 1kqd:D, 1nec:A, 1nec:B, 1nec:C, 1nec:D
8 3qdl:A 178 220 0.2398 0.2978 0.2409 8.73e-19 3qdl:B, 3qdl:C, 3qdl:D
9 6czp:A 219 209 0.2805 0.2831 0.2967 2.74e-18 6czp:B, 6czp:C, 6czp:D, 6czp:E, 6czp:F, 6czp:G, 6czp:H, 7uwt:A, 7uwt:B
10 1ds7:A 217 222 0.3032 0.3088 0.3018 1.34e-17 8c5e:A, 8c5e:B, 8c5f:A, 8c5f:B, 8c5p:A, 8c5p:B, 8ccv:A, 8ccv:B, 8cj0:A, 8cj0:B, 1ds7:B, 1icr:A, 1icr:B, 1icu:A, 1icu:B, 1icu:C, 1icu:D, 1icv:A, 1icv:B, 1icv:C, 1icv:D, 1idt:A, 1idt:B, 8og3:A, 8og3:B, 1oo5:A, 1oo5:B, 1oo6:A, 1oo6:B, 1oon:A, 1oon:B, 1ooq:A, 1ooq:B, 8qes:A, 8qes:C, 8qes:B, 8qes:D, 8qpo:A, 8qpo:B, 8qpo:C, 8qpo:G, 8qpo:D, 8qpo:E, 8qpo:F, 8qpo:H, 3x21:A, 3x21:B, 3x21:C, 3x21:D, 3x21:E, 3x21:F, 3x21:G, 3x21:H, 3x21:I, 3x21:J, 3x22:A, 3x22:B, 7x32:A, 7x32:C, 7x32:B, 7x32:H, 7x32:D, 7x32:F, 7x32:E, 7x32:G, 7xww:B, 7xww:A, 7xww:H, 7xww:I, 1yki:A, 1yki:B, 1yki:C, 1yki:D, 1ylr:A, 1ylr:B, 1ylu:A, 1ylu:B
11 3of4:A 208 187 0.2579 0.2740 0.3048 8.72e-16 3of4:B, 3of4:C
12 8dor:A 217 187 0.2624 0.2673 0.3102 1.85e-15 8dor:B, 8dor:C, 8dor:D
13 1v5y:A 217 219 0.2398 0.2442 0.2420 3.64e-15 1v5y:B, 1v5z:A, 1v5z:B, 1vfr:A, 1vfr:B
14 3ge6:A 210 161 0.1719 0.1810 0.2360 1.27e-09 3ge6:B
15 3bem:B 210 168 0.1855 0.1952 0.2440 9.02e-09 3bem:A
16 3gbh:B 213 211 0.1991 0.2066 0.2085 9.58e-09 3gbh:A, 3gbh:C, 3gbh:D
17 8cqt:B 164 74 0.1222 0.1646 0.3649 1.01e-08 8cqt:A
18 3ge5:A 176 58 0.0995 0.1250 0.3793 5.46e-06 3ge5:B
19 4qlx:A 217 82 0.1222 0.1244 0.3293 5.53e-06 4qlx:B, 4qly:A, 4qly:B, 4qly:C, 4qly:D
20 1nox:A 200 212 0.2715 0.3000 0.2830 6.47e-06
21 4eo3:A 321 226 0.2353 0.1620 0.2301 1.71e-05 4eo3:B
22 3ek3:A 187 64 0.1131 0.1337 0.3906 1.93e-05
23 3gfa:A 197 67 0.0995 0.1117 0.3284 4.83e-05 3gfa:B
24 3koq:A 173 48 0.0724 0.0925 0.3333 0.001 3h4o:A, 3koq:B, 3koq:C, 3koq:D
25 3m5k:A 168 66 0.0950 0.1250 0.3182 0.001 3m5k:B
26 3gag:A 206 168 0.1765 0.1893 0.2321 0.001 3gag:B, 3gag:C, 3gag:D
27 4g8s:A 182 62 0.0950 0.1154 0.3387 0.001 4g8s:B
28 4ttb:A 189 95 0.0950 0.1111 0.2211 0.002 4ttb:B
29 3tnz:A 222 62 0.0679 0.0676 0.2419 0.002 3gfd:A, 3gfd:B, 3gh8:A, 3gh8:B, 3gh8:C, 3gh8:D, 3gh8:E, 3gh8:F, 3gh8:G, 3gh8:H, 3tnz:B
30 4ttc:A 220 65 0.0679 0.0682 0.2308 0.003 4ttc:B, 4ttc:C, 4ttc:D, 4ttc:E, 4ttc:F, 5yak:A, 5yak:F, 5yak:B, 5yak:C, 5yak:D, 5yak:E
31 2b67:A 201 45 0.0679 0.0746 0.3333 0.004 2b67:B, 2b67:C, 2b67:D
32 4dn2:A 191 64 0.0860 0.0995 0.2969 0.004 4dn2:B
33 5ko7:B 200 87 0.1131 0.1250 0.2874 0.006
34 5ko8:B 218 53 0.0769 0.0780 0.3208 0.007 5ko7:A, 5ko8:A, 5krd:A, 5krd:B
35 3e39:A 175 50 0.0814 0.1029 0.3600 0.007 3e39:B
36 3gb5:A 185 59 0.0633 0.0757 0.2373 0.009 3to0:A, 3to0:B
37 6pz0:A 185 54 0.0679 0.0811 0.2778 0.010 6pz0:B, 6q1b:A, 6q1b:B, 6q1l:A, 6q1l:B, 6tyk:A, 6tyk:B
38 3e10:B 167 79 0.0995 0.1317 0.2785 0.013 3e10:A
39 5j6c:A 173 49 0.0814 0.1040 0.3673 0.013 5j6c:B
40 3eo8:A 219 210 0.1991 0.2009 0.2095 0.040 3eo8:B, 3eo8:C, 3eo8:D, 3eo8:E, 3eo8:F
41 5j62:B 209 59 0.0724 0.0766 0.2712 0.040 5j62:A
42 3kwk:A 168 44 0.0724 0.0952 0.3636 0.23
43 2isj:A 219 222 0.2308 0.2329 0.2297 0.36 2isj:B, 2isj:C, 2isj:D, 2isj:E, 2isj:F, 2isj:G, 2isj:H, 2isk:A, 2isk:B, 2isk:C, 2isk:D, 2isk:E, 2isk:F, 2isk:G, 2isk:H, 2isl:A, 2isl:B, 2isl:C, 2isl:D, 2isl:E, 2isl:F, 2isl:G, 2isl:H
44 1ton:A 227 64 0.0814 0.0793 0.2812 0.46
45 8jrk:D 178 102 0.1222 0.1517 0.2647 0.64 8jr4:B, 8jrj:B, 8jrk:B
46 3gr3:A 226 49 0.0633 0.0619 0.2857 0.99 3gr3:B
47 8uc3:A 180 75 0.0905 0.1111 0.2667 1.0 8uc3:B
48 3lwu:A 372 146 0.1674 0.0995 0.2534 1.1
49 1zgl:H 168 120 0.1493 0.1964 0.2750 1.4
50 2wef:A 303 92 0.0905 0.0660 0.2174 1.5 1jp4:A
51 1zch:A 249 84 0.0905 0.0803 0.2381 1.8
52 2fre:A 200 46 0.0633 0.0700 0.3043 4.2 2fre:B
53 3a31:A 465 71 0.0860 0.0409 0.2676 4.6 3a32:A
54 7m8q:A 515 32 0.0543 0.0233 0.3750 5.2 6d7k:A, 6d7k:E, 7m8q:E, 7m8r:A, 7m8r:E, 1mhy:D, 1mhz:D, 7s6q:A, 7s6q:E, 7s6r:A, 7s6r:E, 7s6s:A, 7s6s:E, 7s6t:A, 7s6t:E, 7s7h:A, 7s7h:E, 6vk4:A, 6vk4:E, 6vk5:A, 6vk5:E, 6vk6:A, 6vk7:A, 6vk8:A, 6vk8:E, 6yd0:D, 6ydi:D, 6ydu:D, 6yy3:D
55 4lrs:A 337 27 0.0452 0.0297 0.3704 5.3 4lrt:A, 4lrt:C
56 9br7:C 403 30 0.0498 0.0273 0.3667 6.7 9br7:A, 9br7:D
57 4woe:A 716 84 0.0679 0.0209 0.1786 7.1 4wod:A, 4woe:B
58 1c7n:A 394 30 0.0452 0.0254 0.3333 7.7 1c7n:B, 1c7n:C, 1c7n:D, 1c7n:E, 1c7n:F, 1c7n:G, 1c7n:H, 1c7o:A, 1c7o:B, 1c7o:C, 1c7o:D, 1c7o:E, 1c7o:F, 1c7o:G, 1c7o:H
59 7cbb:A 576 76 0.0995 0.0382 0.2895 8.1 7cbb:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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