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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MTTLQEKIIQELGVLPTIDPKEEVRKSIDFLKAYLTKHPFLKTFVLGISGGQDSTLAGRLAQLAMTEMREETGDMSYQFI
AIRLPYGEQADEADAQAALAFIQPDVSLRVDIKPAVDAMVGSLENAGVQISDFNKGNMKARQRMITQYAVAGENAGAVIG
TDHAAENVTAFFTKYGDGGADILPLFRLNKRQGKALLKELGAPEALYLPLVADEVALGVTYDAIDDYLEGKKVSETDQQT
IENWYKKGQHKRHLPITIFDDFWK

The query sequence (length=264) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6c8q:A 268 268 0.9962 0.9813 0.9813 0.0 6c8q:B, 6c8q:C, 6c8q:G, 6c8q:D, 6c8q:F, 6c8q:E, 6c8q:H
2 5huh:A 261 262 0.7462 0.7548 0.7519 8.56e-146 5huh:B
3 3hmq:A 262 262 0.6477 0.6527 0.6527 9.57e-123
4 1wxi:A 261 262 0.6364 0.6437 0.6412 6.93e-122 1wxe:A, 1wxg:A, 1wxh:A
5 1ee1:A 271 274 0.5985 0.5830 0.5766 5.74e-105 1fyd:A, 1ih8:A, 1kqp:A, 1kqp:B, 1nsy:A, 1nsy:B, 2nsy:A, 2nsy:B
6 2pz8:A 280 274 0.6023 0.5679 0.5803 3.73e-100 2pz8:B, 2pza:A, 2pza:B
7 1ee1:B 246 263 0.5720 0.6138 0.5741 3.69e-98 1ifx:A, 1ifx:B
8 3q4g:A 266 267 0.5076 0.5038 0.5019 7.85e-81
9 5f23:A 263 262 0.4886 0.4905 0.4924 4.45e-70
10 3fiu:A 238 248 0.3447 0.3824 0.3669 2.83e-33 3fiu:B, 3fiu:C, 3fiu:D
11 2e18:A 256 234 0.2727 0.2812 0.3077 1.11e-22 2e18:B
12 1xng:B 262 226 0.2348 0.2366 0.2743 2.11e-07 1xng:A
13 6ofb:A 696 167 0.1667 0.0632 0.2635 0.002 6ofb:B
14 8aya:B 298 71 0.0644 0.0570 0.2394 0.39 4ds8:B, 5jo2:B, 3kb3:B, 4lg5:B, 4lgb:B, 5mn0:B, 7mwn:B, 3nmt:B, 5or2:B, 5or6:B, 3qn1:B, 5vs5:B, 4wvo:B, 3zvu:B
15 3rt0:A 328 71 0.0644 0.0518 0.2394 0.48 7avw:B, 8ay3:B, 8ay6:B, 8ay7:B, 8ay8:B, 8ay9:B, 5jo1:B, 4la7:B, 4lga:B, 3rt0:B, 3ujg:B, 5vr7:B, 5vro:B, 5vsq:B, 5vsr:B, 5vt7:B, 6zuc:B
16 5kha:A 526 143 0.1364 0.0684 0.2517 1.2 5kha:B
17 7cnr:A 386 89 0.0871 0.0596 0.2584 1.2 7cnr:C, 7cnr:E, 7cnr:G, 7cns:A
18 7d9f:A 591 68 0.0833 0.0372 0.3235 1.9 7d9f:B, 7d9g:A, 7d9g:B, 7d9h:A, 7d9h:B, 7d9i:A, 7d9i:B, 7d9j:A, 7d9j:B
19 5wsy:B 165 76 0.0758 0.1212 0.2632 2.5 5wsy:A
20 3lbf:A 207 67 0.0795 0.1014 0.3134 5.1 3lbf:B, 3lbf:C, 3lbf:D
21 6ey7:B 227 112 0.0985 0.1145 0.2321 5.8 6ey7:A, 6ey7:C, 6ey7:D, 3n4p:A, 3n4p:B, 3n4p:C, 3n4p:D, 3n4q:A, 3n4q:B, 3n4q:C, 3n4q:D
22 6ofc:B 669 160 0.1591 0.0628 0.2625 6.3 3dla:A, 3dla:D, 3dla:C, 6ofc:A, 6ofc:D, 6ofc:C, 3seq:A, 3seq:B, 3sez:A, 3sez:B, 3syt:A, 3syt:B, 3syt:C, 3szg:A, 3szg:D, 3szg:C
23 5mga:A 1182 31 0.0530 0.0118 0.4516 7.2
24 6gtd:A 1269 31 0.0530 0.0110 0.4516 7.7 6i1l:D, 5nfv:A, 5ng6:A, 5ng6:C, 5ng6:E, 5ng6:G
25 6gtg:A 1298 31 0.0530 0.0108 0.4516 7.7 6gtc:A, 6gte:A, 6gtf:A, 6i1k:A, 6i1l:A
26 3seq:D 650 157 0.1477 0.0600 0.2484 8.0 3dla:B, 3seq:C, 3sez:D, 3sez:C, 3syt:D, 3szg:B
27 8q72:A 750 58 0.0720 0.0253 0.3276 8.6 8q72:B, 8q72:F, 8q72:G
28 8as8:A 597 58 0.0720 0.0318 0.3276 9.9 8as8:B, 8bfn:A, 8bfn:B, 8bfn:F, 8bfn:G

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218