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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MTTIAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVITMLPTGEVVRRCYTDVLA
AARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSGGVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGA
AGAGQAAKVCNNMVLAVQQIAIAEAFVLAEKLGLSAQSLFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFKPGFSTAL
MNKDLGLAMDAVAATGATAPLGSHAADIYAKFAADHADLDFSAVIHTLRA

The query sequence (length=290) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5y8i:A 292 289 0.9966 0.9897 1.0000 0.0 5y8g:A, 5y8g:B, 5y8h:A, 5y8h:B, 5y8i:B, 5y8j:A, 5y8j:B, 5y8k:A, 5y8k:B, 5y8l:A, 5y8l:B, 5y8m:A, 5y8m:B, 5y8n:A, 5y8n:B, 5y8o:A, 5y8o:B, 5y8p:A, 5y8p:B
2 2i9p:B 296 290 0.4034 0.3953 0.4034 1.48e-65 2i9p:A, 2i9p:C, 2i9p:D
3 3obb:A 295 288 0.4655 0.4576 0.4688 3.47e-61 3q3c:A
4 3w6z:A 296 277 0.3103 0.3041 0.3249 5.91e-39 3w6u:A, 3ws7:A, 5xvh:A
5 5je8:B 294 273 0.2828 0.2789 0.3004 3.20e-38 5je8:A, 5je8:C, 5je8:D
6 2cvz:C 289 276 0.3310 0.3322 0.3478 5.54e-36 2cvz:A, 2cvz:B, 1wp4:A, 1wp4:B, 1wp4:C, 1wp4:D
7 6smz:C 295 291 0.3172 0.3119 0.3162 3.28e-34 6smy:A, 6smy:B, 6smy:C, 6smy:D, 6smz:A, 6smz:B, 6smz:D
8 3pdu:A 287 296 0.3310 0.3345 0.3243 1.14e-27 3pdu:B, 3pdu:C, 3pdu:D, 3pdu:F, 3pdu:E, 3pdu:G, 3pdu:H
9 3pef:A 287 293 0.3069 0.3101 0.3038 1.21e-23 3pef:B, 3pef:C, 3pef:D, 3pef:E, 3pef:F, 3pef:G, 3pef:H
10 2uyy:A 292 287 0.2552 0.2534 0.2578 1.17e-21 2uyy:D
11 7pua:FM 327 241 0.2103 0.1865 0.2531 2.13e-15 6sga:FM, 6sgb:FM
12 5u5g:A 286 213 0.2069 0.2098 0.2817 4.48e-12 5u5g:B, 5u5g:C, 5u5g:D
13 6vpb:B 324 242 0.2241 0.2006 0.2686 5.73e-10
14 7a3w:B 293 163 0.1276 0.1263 0.2270 1.30e-06 7a3w:A
15 8c79:A 478 219 0.1862 0.1130 0.2466 3.75e-05 8c79:B
16 2w90:B 471 215 0.1724 0.1062 0.2326 5.93e-05 2w8z:A, 2w8z:B, 2w90:A
17 7cb5:B 467 212 0.1655 0.1028 0.2264 6.58e-05 7cb2:A, 7cb2:B, 7cb2:C, 7cb2:D, 7cb5:A, 7cb5:C, 7cb5:D
18 6jiz:C 295 110 0.1138 0.1119 0.3000 0.001 6jit:B, 6jit:C, 6jiz:B
19 6toe:B 293 158 0.1103 0.1092 0.2025 0.010 6to4:A, 6to4:D, 6to4:B, 6to4:C, 6toe:A, 6toe:F, 6toe:C
20 4xiy:A 328 75 0.0931 0.0823 0.3600 0.011 4xiy:B, 4xiy:C, 4xiy:D
21 8i4q:A 479 202 0.1586 0.0960 0.2277 0.012 8i4q:B
22 8j43:A 285 159 0.1379 0.1404 0.2516 0.015 8j43:B
23 2iz1:B 471 127 0.1241 0.0764 0.2835 0.018 2iyo:A, 2iyp:A, 2iyp:B, 2iyp:C, 2iz0:A, 2iz0:B, 2iz0:C, 2iz1:A, 2iz1:C
24 8qhe:A 284 110 0.0862 0.0880 0.2273 0.019 6sle:A, 6sle:C, 6sle:H, 6sle:D, 6sle:E, 6sle:F, 6sle:G
25 7w64:C 395 76 0.0724 0.0532 0.2763 0.15 7w64:A, 7w64:B, 7w64:D, 7w64:F, 7w64:E
26 7og3:A 290 206 0.1621 0.1621 0.2282 0.15 7og3:B
27 7q03:A 328 65 0.0759 0.0671 0.3385 0.17 7q07:A
28 5g6r:B 289 107 0.0862 0.0865 0.2336 0.18 5g6r:A, 5g6s:A, 5g6s:G, 5g6s:B, 5g6s:C, 5g6s:D, 5g6s:F, 5g6s:E, 5g6s:H
29 4tsk:A 333 66 0.0862 0.0751 0.3788 0.21
30 5ocm:A 290 159 0.1172 0.1172 0.2138 0.25 5ocm:F, 5ocm:B, 5ocm:C, 5ocm:D, 5ocm:E
31 6bul:B 327 66 0.0862 0.0765 0.3788 0.30 6aqj:A, 6aqj:B, 6bul:A, 6c55:A, 6c55:B, 6c5n:A, 6c5n:B, 7ke2:B, 7ke2:A, 7kh7:A, 7kh7:B, 6vo2:A, 6vo2:B, 5w3k:A, 5w3k:B
32 3zhb:D 294 124 0.1103 0.1088 0.2581 0.46 3zhb:A, 3zhb:B, 3zhb:C
33 8bk1:A 288 148 0.1345 0.1354 0.2635 0.51 8bj5:A, 8bj5:B, 8bj5:C, 8bj5:D, 8bk1:B, 8bk1:C, 8bk1:D
34 3oet:H 378 64 0.0793 0.0608 0.3594 0.52 3oet:A, 3oet:B, 3oet:C, 3oet:D, 3oet:E, 3oet:F, 3oet:G
35 3mmr:A 308 96 0.0793 0.0747 0.2396 0.71 3sl0:A, 3sl1:A
36 7pci:A 345 66 0.0793 0.0667 0.3485 0.78 7pcc:A, 7pcc:B, 7pce:A, 7pcg:A, 7pcg:B, 7pcl:A, 7pcl:B, 7pcm:A, 7pcm:B, 7pcn:A, 7pcn:B, 7pco:A, 7pco:B, 7pct:A, 7pct:B
37 7osn:B 291 115 0.0931 0.0928 0.2348 1.0 7osn:A, 7osn:C, 7osn:D, 7osn:E, 7osn:F
38 8ep7:C 328 95 0.0966 0.0854 0.2947 1.2 8ep7:A, 8ep7:B
39 4zqb:B 316 69 0.0759 0.0696 0.3188 1.4 4zqb:A
40 8j44:A 293 98 0.0862 0.0853 0.2551 1.7 8j44:B, 8whg:B, 8whg:E, 8whg:F
41 6aph:A 432 65 0.0724 0.0486 0.3231 1.7
42 4om8:A 309 40 0.0586 0.0550 0.4250 1.7 4om8:B
43 4jnq:A 315 154 0.1241 0.1143 0.2338 1.9
44 3fwn:A 467 216 0.1552 0.0964 0.2083 2.0 3fwn:B, 2zya:A, 2zya:B, 2zyd:A, 2zyd:B
45 3a74:A 484 67 0.0690 0.0413 0.2985 2.8 3a74:B, 3a74:C, 3a74:D, 3e9h:A, 3e9h:B, 3e9h:C, 3e9h:D, 3e9i:A, 3e9i:B, 3e9i:C, 3e9i:D
46 6gbn:B 435 56 0.0759 0.0506 0.3929 2.9 6gbn:A, 6gbn:C, 6gbn:D
47 3dc2:A 526 97 0.0862 0.0475 0.2577 3.4 3dc2:B, 3ddn:B
48 5a9t:A 286 111 0.0931 0.0944 0.2432 4.0 5a9s:A, 5a9s:B, 5fwn:A, 5fwn:B
49 6ggu:A 344 69 0.0586 0.0494 0.2464 4.1 4jjf:A, 4jjf:B, 4jjg:A, 4jjg:B, 5ok4:A
50 4uin:H 221 50 0.0655 0.0860 0.3800 4.3
51 1y81:A 116 48 0.0379 0.0948 0.2292 4.5
52 8a3x:A 295 120 0.1034 0.1017 0.2500 4.5 8a3x:B, 8a3x:C, 8a3x:D, 8a5z:A, 8a5z:B
53 1qp8:A 301 70 0.0724 0.0698 0.3000 4.6 1qp8:B
54 5e4r:A 466 65 0.0724 0.0451 0.3231 4.8 4xdz:A, 4xdz:B
55 4oqy:A 268 127 0.1034 0.1119 0.2362 6.3
56 5jpi:A 496 70 0.0724 0.0423 0.3000 7.3 5hm8:A, 5hm8:B, 5hm8:C, 5hm8:D, 5hm8:E, 5hm8:F, 5hm8:G, 5hm8:H, 5jpi:B, 5jpi:C, 5jpi:D, 5jxw:A, 5jxw:B, 5jxw:C, 5jxw:D, 5t8k:A, 5t8k:C, 5t8k:B, 5t8k:D, 5tj9:A, 5tj9:B, 5tj9:C, 5tj9:D, 5tls:A, 5tls:B, 5tls:C, 5tls:D, 5utu:A, 5utu:B, 5utu:C, 5utu:D, 5utu:E, 5utu:F, 5utu:G, 5utu:H
57 2f1k:A 279 180 0.1690 0.1756 0.2722 9.4 2f1k:B, 2f1k:C, 2f1k:D
58 8jyt:C 286 41 0.0483 0.0490 0.3415 9.4 8jyt:A, 8jyt:B, 8jyt:D
59 6smt:B 289 36 0.0483 0.0484 0.3889 9.5 6smt:A, 6smt:C, 6smt:D, 6smt:E
60 5eoc:J 214 50 0.0621 0.0841 0.3600 9.6 5eoc:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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