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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MTQFEGFTNLYQVSKTLRFELIPQGKTLKHIQEQGFIEEDKARNDHYKELKPIIDRIYKTYADQCLQLVQLDWENLSAAI
DSYRKEKTEETRNALIEEQATYRNAIHDYFIGRTDNLTDAINKRHAEIYKGLFKAELFNGKVLKQLGTVTTTEHENALLR
SFDKFTTYFSGFYENRKNVFSAEDISTAIPHRIVQDNFPKFKENCHIFTRLITAVPSLREHFENVKKAIGIFVSTSIEEV
FSFPFYNQLLTQTQIDLYNQLLGGISREAGTEKIKGLNEVLNLAIQKNDETAHIIASLPHRFIPLFKQILSDRNTLSFIL
EEFKSDEEVIQSFCKYKTLLRNENVLETAEALFNELNSIDLTHIFISHKKLETISSALCDHWDTLRNALYERRISELTGK
ITKSAKEKVQRSLKHEDINLQEIISAAGKELSEAFKQKTSEILSHAHAALDQPLPTTLKKQEEKEILKSQLDSLLGLYHL
LDWFAVDESNEVDPEFSARLTGIKLEMEPSLSFYNKARNYATKKPYSVEKFKLNFQMPTLARGWDVNVEKNRGAILFVKN
GLYYLGIMPKQKGRYKALSFEPTEKTSEGFDKMYYDYFPDAAKMIPKCSTQLKAVTAHFQTHTTPILLSNNFIEPLEITK
EIYDLNNPEKEPKKFQTAYAKKTGDQKGYREALCKWIDFTRDFLSKYTKTTSIDLSSLRPSSQYKDLGEYYAELNPLLYH
ISFQRIAEKEIMDAVETGKLYLFQIYNKDFAKGHHGKPNLHTLYWTGLFSPENLAKTSIKLNGQAELFYRPKSRMMAHRL
GEKMLNKKLKDQKTPIPDTLYQELYDYVNHRLSHDLSDEARALLPNVITKEVSHEIIKDRRFTSDKFFFHVPITLNYQAA
NSPSKFNQRVNAYLKEHPETPIIGIDRGERNLIYITVIDSTGKILEQRSLNTIQQFDYQKKLDNREKERVAARQAWSVVG
TIKDLKQGYLSQVIHEIVDLMIHYQAVVVLENLNFAVYQQFEKMLIDKLNCLVLKDYPAEKVGGVLNPYQLTDQFTSFAK
MGTQSGFLFYVPAPYTSKIDPLTGFVDPFVWKTIKNHESRKHFLEGFDFLHYDVKTGDFILHFKMNRNLSFQRGLPGFMP
AWDIVFEKNETQFDAKGTPFIAGKRIVPYRDLYPANELIALLEEKGIVFRDGSNILPKLLENDDSHAIDTMVALIRSVLQ
MRNSNAATGEDYINSPVRDLNGVCFDSRFQNPEWPMDADANGAYHIALKGQLLLNHLKESKDLKLQNGISNQDWLAYIQE
LRN

The query sequence (length=1283) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8sfn:A 1302 1307 0.9938 0.9793 0.9755 0.0 8sfh:A, 8sfl:A, 5xh6:A, 5xh7:A
2 5b43:A 1272 1283 0.9891 0.9976 0.9891 0.0
3 8sfo:A 1240 793 0.6118 0.6331 0.9899 0.0 8sfi:A, 8sfp:A, 8sfq:A, 8sfr:A
4 8sfo:A 1240 453 0.3359 0.3476 0.9514 0.0 8sfi:A, 8sfp:A, 8sfq:A, 8sfr:A
5 5kk5:A 1201 796 0.6064 0.6478 0.9774 0.0
6 5kk5:A 1201 428 0.3258 0.3480 0.9766 0.0
7 8kgf:A 1261 1301 0.4513 0.4592 0.4450 0.0
8 8sfj:A 1001 451 0.3203 0.4106 0.9113 0.0
9 8sfj:A 1001 313 0.2377 0.3047 0.9744 0.0
10 8sfj:A 1001 265 0.2034 0.2607 0.9849 2.24e-177
11 6gtg:A 1298 1393 0.3663 0.3621 0.3374 0.0 6gtc:A, 6gte:A, 6gtf:A, 6i1k:A, 6i1l:A
12 6gtd:A 1269 1362 0.3617 0.3656 0.3407 0.0 6i1l:D, 5nfv:A, 5ng6:A, 5ng6:C, 5ng6:E, 5ng6:G
13 5mga:A 1182 1327 0.3507 0.3807 0.3391 0.0
14 6iv6:A 1209 1332 0.3476 0.3689 0.3348 0.0
15 5xut:A 1217 1335 0.3476 0.3665 0.3341 0.0 5id6:A, 6nm9:B, 6nm9:D, 6nma:B, 6nmc:A, 6nmd:A, 6nme:A, 6omv:B, 5xus:A, 5xuu:A, 5xuz:A, 5xuz:E
16 6kl9:A 1180 1341 0.3406 0.3703 0.3259 5.17e-171
17 8h9d:A 1114 1321 0.3196 0.3680 0.3104 2.80e-162
18 8i54:A 1113 814 0.2253 0.2597 0.3550 2.52e-138
19 8i54:A 1113 346 0.0811 0.0934 0.3006 6.87e-24
20 6klb:A 1118 612 0.1769 0.2030 0.3709 4.08e-98 6klb:D
21 6klb:A 1118 599 0.1465 0.1682 0.3139 5.05e-58 6klb:D
22 6p7m:A 1070 616 0.1769 0.2121 0.3685 5.11e-96 6p7n:A, 6p7n:E
23 6p7m:A 1070 609 0.1458 0.1748 0.3071 1.31e-50 6p7n:A, 6p7n:E
24 8d4a:A 1207 42 0.0148 0.0157 0.4524 0.056 8d4b:A
25 8d4a:A 1207 54 0.0171 0.0182 0.4074 2.2 8d4b:A
26 8d49:A 1072 42 0.0148 0.0177 0.4524 0.059
27 8d49:A 1072 78 0.0195 0.0233 0.3205 0.86
28 8d49:A 1072 53 0.0171 0.0205 0.4151 2.6
29 7wbt:A 899 87 0.0226 0.0323 0.3333 1.8 7wbt:B, 7wbu:A
30 6xyw:Bw 337 96 0.0226 0.0861 0.3021 3.0
31 2ekp:A 238 35 0.0117 0.0630 0.4286 6.6
32 5z6t:A 317 36 0.0109 0.0442 0.3889 7.3 5z6t:B
33 8duz:A 209 36 0.0109 0.0670 0.3889 7.3 8duz:C
34 1mqq:A 675 74 0.0164 0.0311 0.2838 7.7 1k9e:A, 1k9f:A, 1l8n:A
35 8jib:E 661 112 0.0203 0.0393 0.2321 8.5 8ji8:A, 8ji8:B, 8ji8:C, 8ji8:D, 8jib:A, 8jib:B, 8jib:C, 8jib:D, 8jib:F, 8jib:G, 8jib:H, 8jib:I, 8jib:J, 8jib:K, 8jib:L
36 5gzs:A 432 56 0.0140 0.0417 0.3214 8.7
37 8wgo:A 869 78 0.0179 0.0265 0.2949 9.6 8w7j:A, 8wgo:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218