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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MTQFEGFTNLYQVSKTLRFELIPQGKTLKHIQEQGFIEEDKARNDHYKELKPIIDRIYKTYADQCLQLVQLDWENLSAAI
DSYRKEKTEETRNALIEEQATYRNAIHDYFIGRTDNLTDAINKRHAEIYKGLFKAELFNGKVLKQLGTVTTTEHENALLR
SFDKFTTYFSGFYENRKNVFSAEDISTAIPHRIVQDNFPKFKENCHIFTRLITAVPSLREHFENVKKAIGIFVSTSIEEV
FSFPFYNQLLTQTQIDLYNQLLGGISREAGTEKIKGLNEVLNLAIQKNDETAHIIASLPHRFIPLFKQILSDRNTLSFIL
EEFKSDEEVIQSFCKYKTLLRNENVLETAEALFNELNSIDLTHIFISHKKLETISSALCDHWDTLRNALYERRISELKSA
KEKVQRSLKHEDINLQEIISAAGKELSEAFKQKTSEILSHAHAALDQPLPTTLKKQEEKEILKSQLDSLLGLYHLLDWFA
VDESNEVDPEFSARLTGIKLEMEPSLSFYNKARNYATKKPYSVEKFKLNFQMPTLASGWDVNKEKNNGAILFVKNGLYYL
GIMPKQKGRYKALSFEPTEKTSEGFDKMYYDYFPDAAKMIPKCSTQLKAVTAHFQTHTTPILLSNNFIEPLEITKEIYDL
NNPEKEPKKFQTAYAKKTGDQKGYREALCKWIDFTRDFLSKYTKTTSIDLSSLRPSSQYKDLGEYYAELNPLLYHISFQR
IAEKEIMDAVETGKLYLFQIYNKDFAKGHHGKPNLHTLYWTGLFSPENLAKTSIKLNGQAELFYRPKSHEIIKDRRFTSD
KFFFHVPITLNYQAANSPSKFNQRVNAYLKEHPETPIIGIDRGERNLIYITVIDSTGKILEQRSLNTIQQFDYQKKLDNR
EKERVAARQAWSVVGTIKDLKQGYLSQVIHEIVDLMIHYQAVVVLENLNFGFKSKRTGIAEKAVYQQFEKMLIDKLNCLV
LKDYPAEKVGGVLNPYQLTDQFTSFAKMGTQSGFLFYVPAPYTSKIDPLTGFVDPFVWKTIKNHESRKHFLEGFDFLHYD
VKTGDFILHFKMNRNLSFQRGLPGFMPAWDIVFEKNETQFDAKGTPFIAGKRIVPVIENHRFTGRYRDLYPANELIALLE
EKGIVFRDGSNILPKLLENDDSHAIDTMVALIRSVLQMRNSNAATGEDYINSPVRDLNGVCFDSRFQNPEWPMDADANGA
YHIALKGQLLLNHLKESKDLKLQNGISNQDWLAYIQELRN

The query sequence (length=1240) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8sfo:A 1240 1240 1.0000 1.0000 1.0000 0.0 8sfi:A, 8sfp:A, 8sfq:A, 8sfr:A
2 5b43:A 1272 1299 0.9750 0.9505 0.9307 0.0
3 5kk5:A 1201 1241 0.9637 0.9950 0.9629 0.0
4 8sfn:A 1302 788 0.6355 0.6052 1.0000 0.0 8sfh:A, 8sfl:A, 5xh6:A, 5xh7:A
5 8sfn:A 1302 453 0.3653 0.3479 1.0000 0.0 8sfh:A, 8sfl:A, 5xh6:A, 5xh7:A
6 8sfj:A 1001 718 0.5613 0.6953 0.9694 0.0
7 8sfj:A 1001 313 0.2460 0.3047 0.9744 0.0
8 8kgf:A 1261 1287 0.4645 0.4568 0.4476 0.0
9 6gtg:A 1298 1362 0.3806 0.3636 0.3465 0.0 6gtc:A, 6gte:A, 6gtf:A, 6i1k:A, 6i1l:A
10 5mga:A 1182 1298 0.3637 0.3816 0.3475 0.0
11 6gtd:A 1269 1343 0.3694 0.3609 0.3410 0.0 6i1l:D, 5nfv:A, 5ng6:A, 5ng6:C, 5ng6:E, 5ng6:G
12 6iv6:A 1209 1305 0.3573 0.3664 0.3395 0.0
13 5xut:A 1217 1315 0.3621 0.3689 0.3414 0.0 5id6:A, 6nm9:B, 6nm9:D, 6nma:B, 6nmc:A, 6nmd:A, 6nme:A, 6omv:B, 5xus:A, 5xuu:A, 5xuz:A, 5xuz:E
14 6kl9:A 1180 1315 0.3540 0.3720 0.3338 4.19e-177
15 8h9d:A 1114 1300 0.3290 0.3662 0.3138 1.34e-163
16 8i54:A 1113 785 0.2331 0.2597 0.3682 4.89e-141
17 8i54:A 1113 346 0.0839 0.0934 0.3006 6.90e-24
18 6klb:A 1118 585 0.1839 0.2039 0.3897 3.10e-103 6klb:D
19 6klb:A 1118 599 0.1516 0.1682 0.3139 9.96e-58 6klb:D
20 6p7m:A 1070 593 0.1863 0.2159 0.3895 7.97e-102 6p7n:A, 6p7n:E
21 6p7m:A 1070 614 0.1492 0.1729 0.3013 2.23e-49 6p7n:A, 6p7n:E
22 8d4a:A 1207 237 0.0468 0.0481 0.2447 0.009 8d4b:A
23 8d4a:A 1207 54 0.0177 0.0182 0.4074 2.4 8d4b:A
24 8d49:A 1072 166 0.0355 0.0410 0.2651 0.016
25 8d49:A 1072 78 0.0202 0.0233 0.3205 0.76
26 8d49:A 1072 53 0.0177 0.0205 0.4151 2.7
27 1if1:A 105 76 0.0185 0.2190 0.3026 3.4 1if1:B
28 7wbt:A 899 87 0.0226 0.0311 0.3218 4.6 7wbt:B, 7wbu:A
29 8duz:A 209 70 0.0177 0.1053 0.3143 6.3 8duz:C
30 2ekp:A 238 35 0.0121 0.0630 0.4286 6.3
31 5z6t:A 317 36 0.0113 0.0442 0.3889 7.0 5z6t:B
32 1mqq:A 675 74 0.0169 0.0311 0.2838 7.7 1k9e:A, 1k9f:A, 1l8n:A
33 5gzs:A 432 56 0.0145 0.0417 0.3214 7.9
34 6dwo:A 712 176 0.0339 0.0590 0.2386 8.1 6dwo:B, 6dwo:C, 6dwo:D, 7fe1:A, 7fe1:B, 7fe1:C, 7fe1:D, 7fe2:A, 7fe2:B, 7fe2:C, 7fe2:D
35 3cvh:H 213 67 0.0177 0.1033 0.3284 9.0 3cvh:Q
36 8wgo:A 869 78 0.0185 0.0265 0.2949 9.8 8w7j:A, 8wgo:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218