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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MTPKYEDLRAYYTKPSFEFEKQFGFMLKPWTTVRFMNVIPNRFIYKIALVGKDEKKYKDGPYDNIDVFIVLEDNKYQLKK
YSVGGITKTNSKKVNHKVELSITKKDNQGMISRDVSEYMITKEEISLKELDFKLRKQLIEKHNLYGNMGSGTIVIKMKNG
GKYTFELHKKLQEHRMADVIDGTNIDNIEVNIK

The query sequence (length=193) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5i4d:B 193 193 1.0000 1.0000 1.0000 2.43e-141 5i4d:A
2 4dxg:A 194 193 0.7668 0.7629 0.7668 1.76e-107 4rco:A, 4rco:B
3 4rfb:A 194 190 0.4456 0.4433 0.4526 3.65e-46 4rfb:D, 4rfb:B, 4rfb:C, 4rgt:A, 4rgt:B
4 2rdg:A 192 191 0.4663 0.4688 0.4712 2.02e-44
5 2r61:A 195 190 0.3679 0.3641 0.3737 1.24e-28 2z8l:A
6 5u75:A 144 71 0.1606 0.2153 0.4366 3.58e-07
7 1hqr:D 205 123 0.1865 0.1756 0.2927 1.05e-06
8 1eu4:A 204 95 0.1554 0.1471 0.3158 1.41e-05
9 3ea6:A 215 147 0.2124 0.1907 0.2789 0.003
10 1eu3:A 210 115 0.1917 0.1762 0.3217 0.042 1eu3:B
11 2ici:A 227 71 0.1244 0.1057 0.3380 0.056
12 2xn9:C 215 50 0.0881 0.0791 0.3400 0.16 1ewc:A, 1hxy:D
13 2g9h:D 213 76 0.1192 0.1080 0.3026 0.93
14 6lon:A 804 52 0.0933 0.0224 0.3462 1.1 6lon:B, 6lon:C, 6lon:D
15 5fka:C 221 90 0.1036 0.0905 0.2222 2.7 4udu:C
16 1dyq:A 228 40 0.0777 0.0658 0.3750 3.6 1i4g:A, 1i4h:A, 1i4h:B, 1sxt:A, 1sxt:B
17 2gbp:A 309 40 0.0881 0.0550 0.4250 3.9 2fvy:A, 2fw0:A, 8fxt:A, 3ga5:A, 3ga5:B, 3gbp:A, 1gca:A, 1gcg:A, 1glg:A, 2hph:A, 2ipl:A, 2ipm:A, 2ipn:A, 2qw1:A
18 7fct:B 239 74 0.1140 0.0921 0.2973 4.2 7fct:A
19 1yix:A 265 26 0.0570 0.0415 0.4231 5.7 1yix:B
20 1se3:A 239 63 0.0829 0.0669 0.2540 6.2
21 4v4n:Ak 212 100 0.1347 0.1226 0.2600 6.2 4v6u:Bk
22 5w4l:G 357 76 0.1036 0.0560 0.2632 6.7 6bf4:G, 8dcq:A, 4dko:A, 4dko:C, 4dkp:A, 4dkp:C, 4dkq:A, 4dkr:A, 4dkr:C, 4dku:A, 4dku:B, 4dkv:A, 4dkv:B, 4dvs:A, 4dvs:B, 4dvt:A, 4dvt:B, 4dvv:A, 4dvv:B, 4dvw:A, 4dvw:B, 4dvx:A, 4dvx:B, 8f9z:A, 8fa0:A, 8gcz:A, 8gd0:A, 8gd1:A, 8gd3:A, 8gd5:A, 8gdj:A, 8gdk:A, 8gjt:A, 4i54:A, 4i54:B, 5kjr:G, 4lsq:G, 6mfp:G, 6mfp:A, 6mg7:G, 7n8q:G, 3ngb:G, 3ngb:A, 3ngb:D, 3ngb:I, 6one:A, 6onf:A, 6onh:A, 6onv:A, 6ooo:A, 6p9n:A, 4rfn:G, 4rfn:A, 4rfo:G, 4rz8:A, 4rz8:B, 4rz8:C, 4rz8:D, 3se9:G, 5u6e:A, 5u6e:B, 5uem:G, 6usw:A, 6ut1:A, 5w4l:A, 6w4m:G
23 4y9w:A 327 63 0.0984 0.0581 0.3016 7.1
24 6emu:A 170 29 0.0570 0.0647 0.3793 7.7 6emu:B, 6emu:C, 6emv:A, 6emv:B, 6emv:C
25 6hiv:Cv 1059 39 0.0622 0.0113 0.3077 7.9 6hiw:Cv, 6hiy:Cv, 7pub:Cv
26 1ty2:A 211 106 0.1451 0.1327 0.2642 8.7 1ty2:B, 1ty2:C
27 1ck1:A 239 29 0.0674 0.0544 0.4483 9.3 2aq2:B, 3bvg:A, 3bvm:A, 3bvz:A, 1cqv:A, 1i4p:A, 1i4q:A, 1i4r:A, 1i4x:A, 1ste:A, 1uns:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218