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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MTIVHRRLALAIGDPHGIGPEIALKALQQLSATERSLIKVYGPWSALEQAAQICQMESLLQDLIHEEAGSLAQPVQCGEI
TPQAGLSTVQSATAAIRACESGEVDAVIACPHHETAIHRAGIAFSGYPSLLANVLGMNEDEVFLMLVGAGLRIVHVTLHE
SVRSALERLSPQLVINAVDAAVQTCTLLGVPKPQVAVFGINPHASEGQLFGLEDSQITVPAVETLRKRGTVDGPMGADMV
LAQRKHDLYVAMLHDQGHIPIKLLAPNGASALSIGGRVVLSSVGHGSAMDIAGRGVADATALLRTIALLGA

The query sequence (length=311) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8zj7:C 315 312 1.0000 0.9873 0.9968 0.0 8zhy:A, 8zhy:B, 8zhy:D, 8zi8:A, 8zi8:C, 8zi8:D, 8zj0:B, 8zj0:C, 8zj0:D, 8zj3:A, 8zj3:C, 8zj3:B, 8zj3:D, 8zj5:B, 8zj5:C, 8zj5:D, 8zj7:B, 8zj7:A, 8zj7:D
2 4jqp:A 330 317 0.3376 0.3182 0.3312 4.54e-50 4jqp:B
3 6e85:A 331 330 0.3344 0.3142 0.3152 3.93e-41
4 6xmy:A 325 318 0.3087 0.2954 0.3019 3.23e-36
5 3lxy:A 329 325 0.3344 0.3161 0.3200 9.43e-29
6 1ptm:A 329 322 0.2894 0.2736 0.2795 2.06e-28 1ps6:A, 1ps6:B, 1ps7:A, 1ps7:B, 1ps7:C, 1ps7:D, 1ptm:B, 1r8k:A, 1r8k:B
7 3ty3:A 358 37 0.0579 0.0503 0.4865 7.93e-04 3ty3:B
8 2g4o:A 337 25 0.0514 0.0475 0.6400 0.083 2g4o:D
9 4y1p:B 336 81 0.0804 0.0744 0.3086 0.092 4y1p:A
10 3asj:A 333 46 0.0611 0.0571 0.4130 0.28 3asj:B, 3asj:C, 3asj:D, 4yb4:A, 4yb4:B, 4yb4:C, 4yb4:D
11 1tyo:A 427 90 0.0932 0.0679 0.3222 0.49 1xkd:A, 1xkd:B
12 2y42:D 355 25 0.0418 0.0366 0.5200 1.3 4f7i:A, 4f7i:B, 4f7i:C, 4f7i:D, 1hex:A, 4wuo:A, 4wuo:B, 2y40:A, 2y40:B, 2y41:A, 2y41:B, 2y42:A, 2y42:B, 2y42:C, 2ztw:A
13 3blw:F 347 31 0.0482 0.0432 0.4839 2.4 3blw:H, 3blw:J
14 6s6t:A 1472 198 0.1768 0.0374 0.2778 2.9 6s6s:A, 6s6s:B, 6s6s:C, 6s6s:D, 6s6t:B, 6s6t:C, 6s6t:D, 6s6u:A, 6s6u:B, 6s6u:C, 6s6u:D, 6s6u:E, 6s6u:F, 6s6x:A, 6s6x:B, 6s6x:C, 6s6x:D, 6s6x:E, 6s6x:F, 2vdc:A, 2vdc:B, 2vdc:C, 2vdc:D, 2vdc:E, 2vdc:F
15 7ql6:C 427 65 0.0579 0.0422 0.2769 3.2 8esk:B, 8f2s:B, 8f6y:B, 8f6z:B, 7ql5:C, 7smq:B, 7sms:B
16 6lky:A 339 37 0.0482 0.0442 0.4054 3.7 6lky:B
17 4iwh:A 358 30 0.0450 0.0391 0.4667 4.5 4iwh:B, 4xxv:A, 4xxv:B
18 6kde:A 336 35 0.0482 0.0446 0.4286 5.7 5gre:A, 5grh:A, 5gri:A, 5grl:A, 8grd:A, 8gru:A, 8gru:C, 6kde:C, 6kdy:A, 6kdy:C, 6kdy:E, 6kdy:G, 6ke3:A, 6ke3:C, 6ke3:E, 6ke3:G, 6l57:A, 6l59:A, 5yvt:A
19 1jcg:A 335 32 0.0418 0.0388 0.4062 7.4
20 8pu0:A 1157 75 0.0707 0.0190 0.2933 9.3
21 8ptx:A 1215 75 0.0707 0.0181 0.2933 9.3
22 6e20:B 133 29 0.0418 0.0977 0.4483 9.6 6e20:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218