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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDPCAGLVVWL
HTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERI
GSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMT
PATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKV
MSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLG
DRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDT
RLPAFKDALRWNEVYYGF

The query sequence (length=498) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4f2d:A 498 498 0.9980 0.9980 0.9980 0.0 4f2d:B, 4f2d:C, 2hxg:A, 2hxg:B, 2hxg:C
2 7chl:A 498 490 0.6446 0.6446 0.6551 0.0 7chl:B, 7chl:C, 7chl:D, 7chl:E, 7chl:F, 7chl:G, 7chl:H, 7chl:I, 7chl:J, 7chl:K, 7chl:L, 7cxo:A, 7cxo:B, 7cxo:C, 7cxo:D, 7cxo:E, 7cxo:F
3 4r1q:E 496 490 0.5984 0.6008 0.6082 0.0 4r1p:A, 4r1p:B, 4r1p:C, 4r1p:D, 4r1p:E, 4r1p:F, 4r1q:A, 4r1q:D, 4r1q:B, 4r1q:F, 4r1q:C
4 7cyy:C 497 490 0.5743 0.5755 0.5837 0.0 7cx7:A, 7cx7:B, 7cx7:C, 7cx7:D, 7cx7:E, 7cx7:F, 7cyy:A, 7cyy:B, 7cyy:D, 7cyy:E, 7cyy:F
5 7ch3:B 495 498 0.5462 0.5495 0.5462 0.0 7ch3:C, 7ch3:D, 7ch3:E, 7ch3:I, 7ch3:F, 7ch3:G, 7ch3:H, 7ch3:J, 7ch3:K, 7ch3:L, 7cwv:A, 7cwv:B, 7cwv:C, 7cwv:D, 7cwv:E, 7cwv:F, 7cwv:G, 7cwv:H, 7cwv:I, 7cwv:J, 7cwv:K, 7cwv:L
6 7ch3:A 469 498 0.5321 0.5650 0.5321 0.0
7 7l9t:A 156 55 0.0361 0.1154 0.3273 0.053 6cxm:A, 6cxm:B
8 3vif:A 473 77 0.0422 0.0444 0.2727 1.3 3ahz:A, 3ai0:A, 3vig:A, 3vij:A, 3vik:A, 3vil:A, 3vim:A, 3vin:A, 3vio:A, 3vip:A
9 8ui7:C 339 315 0.1205 0.1770 0.1905 3.3 8ui8:C, 8ui9:C, 8uii:C, 8umt:C, 8umu:C, 8umv:C, 8umw:C, 8umy:C, 8un0:C, 8unj:C, 6vvo:C, 7z6h:G
10 8c8v:A 1032 59 0.0301 0.0145 0.2542 6.2 8c8u:A, 8c8w:A, 8c9d:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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