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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MSVKIGINGFGRIGRLAFRRILELGEKSSDIEVVAINDLTSPALLAHLLKYDSTHGTLNADVSATDDSIVVNGKNYRVYA
EPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGAKRVLISAPAGSDLKTIVYNVNDDILTADDRIVSAGSCTTNC
LAPLAFFENKEFGIKVGTMTTIHAYTSTQMLLDGPVRGGNFRAARAAGVNTIPHSTGAAKALGLVIPELNGKLQGHAQRV
GVVDGSLTELVAILDKKVTADEVNAAIKKHTEGNESFGYNDDEIVSSDVIGTTFGSIFDPTQTEVTSDGDNQLVKTVAWY
DNEYGFTCQMVRTLLKFATL

The query sequence (length=340) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8hmn:D 340 340 1.0000 1.0000 1.0000 0.0 8hmn:A, 8hmn:B, 8hmn:C, 6iqm:A, 6iqm:B, 6iqm:C, 6iqm:D
2 7www:A 336 338 0.8324 0.8423 0.8373 0.0
3 7c5o:O 338 337 0.6706 0.6746 0.6766 2.01e-162 7c5f:O, 7c5f:P, 7c5f:Q, 7c5f:R, 7c5g:O, 7c5g:P, 7c5g:Q, 7c5g:R, 7c5h:O, 7c5h:P, 7c5h:Q, 7c5h:R, 7c5i:O, 7c5i:P, 7c5i:Q, 7c5i:R, 7c5j:O, 7c5j:P, 7c5j:Q, 7c5j:R, 7c5k:O, 7c5k:P, 7c5k:Q, 7c5k:R, 7c5l:O, 7c5l:P, 7c5l:Q, 7c5l:R, 7c5m:O, 7c5m:P, 7c5m:Q, 7c5m:R, 7c5n:O, 7c5n:P, 7c5n:Q, 7c5n:R, 7c5o:P, 7c5o:Q, 7c5o:R, 7c5p:O, 7c5p:P, 7c5p:Q, 7c5p:R, 7c5q:O, 7c5q:P, 7c5q:Q, 7c5q:R, 7c5r:O, 7c5r:P, 7c5r:Q, 7c5r:R, 7c7k:O, 7c7k:P, 7c7k:Q, 7c7k:R
4 5vmt:B 334 338 0.5882 0.5988 0.5917 1.65e-145 5vmt:A, 5vmt:C, 5vmt:D, 5vmt:F, 5vmt:G, 5vmt:H
5 5ld5:C 342 342 0.6059 0.6023 0.6023 2.27e-137 5ld5:A, 5ld5:B, 5ld5:D
6 3lvf:P 338 341 0.5853 0.5888 0.5836 6.39e-135 3hq4:R, 3hq4:O, 3hq4:P, 3hq4:Q, 3k73:Q, 3k73:O, 3k73:P, 3k73:R, 3k9q:Q, 3k9q:O, 3k9q:P, 3k9q:R, 3ksd:Q, 3ksd:R, 3ksd:O, 3ksd:P, 3ksz:O, 3ksz:P, 3ksz:R, 3ksz:Q, 3kv3:O, 3kv3:Q, 3kv3:R, 3kv3:P, 3l4s:Q, 3l4s:P, 3l4s:O, 3l4s:R, 3l6o:Q, 3l6o:P, 3l6o:R, 3l6o:O, 3lc1:P, 3lc1:R, 3lc1:O, 3lc1:Q, 3lc2:O, 3lc2:Q, 3lc2:R, 3lc2:P, 3lvf:R, 3lvf:O, 3lvf:Q, 5t73:A, 5t73:B, 5t73:C, 5t73:D, 3vaz:P, 3vaz:R, 3vaz:O, 3vaz:Q, 3vaz:B, 3vaz:A
7 5utm:A 345 341 0.5676 0.5594 0.5660 1.89e-133 5jy6:A, 5jy6:B, 5jy6:C, 5jy6:D, 5jya:A, 5jya:B, 5jya:C, 5jya:D, 5jye:A, 5jye:C, 4qx6:A, 4qx6:B, 4qx6:C, 4qx6:D, 5utl:A, 5utl:B, 5utl:C, 5utl:D, 5utm:B, 5utm:C, 5utm:D, 5v8x:A, 5v8x:B, 5v8x:C, 5v8x:D, 5y37:A, 5y37:B
8 5m6d:A 346 338 0.5588 0.5491 0.5621 5.82e-133 6fzh:A, 6fzh:B, 6ite:P, 6ite:Q, 6ite:R, 6ite:O
9 6fzi:B 332 332 0.5706 0.5843 0.5843 1.76e-129 6fzi:A, 6fzi:C, 6fzi:D
10 5vmt:E 293 332 0.5353 0.6212 0.5482 1.15e-120
11 7jwk:C 333 340 0.4882 0.4985 0.4882 4.11e-112 7jwk:A, 7jwk:B, 7jwk:D
12 1hdg:O 332 333 0.4971 0.5090 0.5075 1.75e-111 1hdg:Q
13 7xzg:A 334 336 0.4735 0.4820 0.4792 5.71e-99 7xzg:B, 7xzg:C, 7xzg:D
14 8hrq:B 336 334 0.4765 0.4821 0.4850 4.13e-98 8hro:A, 8hro:B, 8hrp:A, 8hrp:B, 8hrp:C, 8hrp:D, 8hrp:E, 8hrp:F, 8hrp:G, 8hrp:H, 8hrq:A, 8hrr:A, 8hrr:B, 8hrs:A, 8hrs:B, 8hrs:C, 8hrs:D, 8hrt:A, 8hrt:B, 8hrt:C, 8hrt:D
15 3cmc:O 334 333 0.4824 0.4910 0.4925 1.81e-97 3cmc:P, 3cmc:Q, 3cmc:R, 1dbv:O, 1dbv:P, 1dbv:Q, 1dbv:R, 2dbv:O, 2dbv:P, 2dbv:Q, 2dbv:R, 3dbv:O, 3dbv:P, 3dbv:Q, 3dbv:R, 4dbv:O, 4dbv:P, 4dbv:Q, 4dbv:R, 1gd1:O, 1gd1:P, 1gd1:Q, 1gd1:R, 1npt:O, 1npt:P, 1npt:Q, 1npt:R, 1nq5:O, 1nq5:Q, 1nq5:A, 1nq5:C, 1nqa:O, 1nqa:P, 1nqa:Q, 1nqa:R, 1nqo:O, 1nqo:Q, 1nqo:A, 1nqo:C
16 3hja:A 334 338 0.4735 0.4820 0.4763 2.57e-97 3hja:B, 3hja:C, 3hja:D
17 3gnq:C 335 340 0.4765 0.4836 0.4765 6.53e-97 3gnq:B, 3gnq:D, 3gnq:E, 3gnq:F, 3gnq:G, 3gnq:H
18 8br4:A 339 336 0.4882 0.4897 0.4940 7.19e-97 8br4:B, 8br4:C, 8br4:D, 8br4:E, 8br4:F, 8br4:G, 8br4:H, 8br4:I, 8br4:J, 8br4:K, 8br4:L, 8br4:M, 8br4:N, 8br4:O, 8br4:P
19 2ep7:B 339 348 0.4676 0.4690 0.4569 1.83e-95 2ep7:A
20 3doc:A 335 343 0.4706 0.4776 0.4665 5.04e-93 3doc:B, 3doc:C, 3doc:D
21 6nlx:C 335 337 0.4412 0.4478 0.4451 6.00e-92 6nlx:B, 6nlx:D, 5ur0:A, 5ur0:B, 5ur0:C, 5ur0:D
22 8de5:A 338 344 0.4500 0.4527 0.4448 1.93e-91
23 3sth:C 340 337 0.4618 0.4618 0.4659 2.70e-91 3sth:A, 3sth:B, 3sth:D
24 7bew:A 330 333 0.4382 0.4515 0.4474 1.99e-90 7bex:A
25 6ok4:A 334 334 0.4529 0.4611 0.4611 7.52e-90 6ok4:B, 6ok4:C, 6ok4:D, 6wyc:A, 6wyc:B, 6wyc:C, 6wyc:D, 6x2e:A, 6x2e:C, 6x2e:D
26 3l0d:A 332 341 0.4618 0.4729 0.4604 1.23e-89 3l0d:B
27 4mvj:B 332 333 0.4412 0.4518 0.4505 1.85e-88 1dc4:A, 1dc4:B, 1dc6:A, 1dc6:B, 1gad:O, 1gad:P, 1gae:O, 1gae:P, 6io6:A, 4mvj:A, 4mvj:C, 4mvj:D, 4mvj:E, 4mvj:F, 4mvj:G, 4mvj:I, 4mvj:J, 4mvj:K, 4mvj:L, 4mvj:M, 4mvj:O, 4mvj:P, 6utm:A, 6utm:B, 6utn:A, 6utn:B, 6uto:A, 6uto:B, 2vyn:A, 2vyn:B, 2vyn:C, 2vyv:A, 2vyv:B, 2vyv:C, 5za0:A
28 8oha:B 336 332 0.4353 0.4405 0.4458 7.79e-88 8oha:A, 8oha:C, 8oha:D, 8oha:E, 8oha:F, 8oha:G, 8oha:H
29 1obf:O 335 343 0.4441 0.4507 0.4402 1.20e-87 1obf:P
30 3pym:A 332 332 0.4412 0.4518 0.4518 4.07e-87 3pym:B
31 1dss:G 333 336 0.4441 0.4535 0.4494 4.89e-87 1dss:R, 1gpd:G, 1gpd:R, 1ihx:A, 1ihx:B, 1ihx:C, 1ihx:D, 1ihy:A, 1ihy:B, 1ihy:C, 1ihy:D, 1szj:G, 1szj:R
32 6m5x:O 334 335 0.4353 0.4431 0.4418 5.21e-87 6m5x:R, 6m5x:P, 6m5x:Q
33 6qun:O 334 341 0.4382 0.4461 0.4370 3.90e-85 6qun:R, 6quq:O, 6quq:R, 4z0h:O, 4z0h:R
34 6px2:A 332 344 0.4676 0.4789 0.4622 5.47e-85 6px2:B, 6px2:C, 6px2:D, 6px2:E, 6px2:F, 6px2:G, 6px2:H
35 4p8r:A 331 333 0.4324 0.4441 0.4414 7.26e-85 4p8r:B, 4p8r:C, 4p8r:D
36 1ywg:O 337 328 0.4500 0.4540 0.4665 2.48e-84 2b4r:O, 2b4r:P, 2b4r:Q, 2b4r:R, 2b4t:O, 2b4t:P, 2b4t:Q, 2b4t:R, 1ywg:P, 1ywg:Q, 1ywg:R
37 4lsm:A 331 332 0.4147 0.4260 0.4247 2.73e-84 4lsm:B
38 3e5r:O 336 341 0.4353 0.4405 0.4340 4.01e-83 3e5r:A, 3e5r:B, 3e5r:C, 3v1y:O, 3v1y:A, 3v1y:B, 3v1y:C
39 3cif:A 338 332 0.4235 0.4260 0.4337 8.26e-83 3cif:B, 3cif:C, 3cif:D, 3cps:A, 3cps:B, 8pvf:A, 1vsv:A, 1vsv:B, 1vsv:C, 1vsv:D
40 4k9d:A 338 336 0.4471 0.4497 0.4524 5.68e-82 4k9d:B, 4k9d:C, 4k9d:D, 4k9d:E, 4k9d:F, 4k9d:G, 4k9d:H
41 3dmt:A 359 354 0.4235 0.4011 0.4068 1.27e-81 3dmt:B, 3dmt:C, 3dmt:D, 3ids:D, 1k3t:C, 1ml3:B, 1ml3:C, 1ml3:D, 1qxs:C, 1qxs:D, 1qxs:A, 1qxs:B, 2x0n:A, 2x0n:B, 2x0n:O, 2x0n:P, 2x0n:Q, 2x0n:R
42 1a7k:A 358 344 0.4294 0.4078 0.4244 2.10e-80 1a7k:B, 1a7k:C, 1a7k:D, 1gyp:A, 1gyp:B, 1gyp:C, 1gyp:D, 1gyq:A, 1gyq:B, 1gyq:C, 1gyq:D, 1i32:A, 1i32:B, 1i32:C, 1i32:D, 1i32:E, 1i32:F, 1i33:A, 1i33:B, 1i33:C, 1i33:D, 1i33:E, 1i33:F
43 6ghr:B 342 332 0.4412 0.4386 0.4518 2.46e-80 4boy:A, 4boy:B, 6gfo:A, 6gfo:B, 6gfo:C, 6gfo:D, 6gfp:A, 6gfp:B, 6gfq:B, 6gfq:A, 6gfr:A, 6gfr:B, 6gg7:B, 6gg7:A, 6ghl:A, 6ghl:D, 6ghl:B, 6ghl:C, 6ghr:D, 6ghr:A, 6ghr:C, 6gve:D, 6gve:A, 6gve:E, 6gve:F, 6gve:I, 6gve:K, 6gve:N, 6gve:O, 3zcx:A, 3zcx:B, 3zdf:B, 3zdf:A
44 3gpd:R 334 340 0.4176 0.4251 0.4176 2.51e-79 3gpd:G
45 6m61:O 336 340 0.4147 0.4196 0.4147 8.75e-79 6ade:A, 5ddi:P, 5ddi:R, 5ddi:S, 6iq6:A, 6iq6:B, 6iq6:C, 6iq6:D, 6iq6:E, 1j0x:P, 1j0x:R, 6lgj:A, 6lgj:B, 6lgj:C, 6lgj:D, 6lgk:A, 6lgk:B, 6lgk:C, 6lgm:A, 6lgm:B, 6lgm:C, 6m61:Q, 6m61:P, 4o59:O, 4o59:P, 4o59:R, 4o59:Q, 4o63:P, 4o63:Q, 4o63:R, 8p5f:AAA, 8p5f:DDD, 8p5f:EEE, 8p5f:GGG, 5tso:P, 5tso:R, 5tso:S, 7u5m:A, 7u5m:B, 7u5m:C, 7u5m:D, 1u8f:P, 1u8f:Q, 1u8f:R, 4wnc:O, 4wnc:E, 4wnc:A, 4wnc:B, 4wnc:C, 4wnc:D, 4wni:O, 4wni:A, 4wni:B, 1znq:O, 1znq:P, 1znq:R, 1znq:Q
46 2i5p:O 309 332 0.4324 0.4757 0.4428 1.52e-78 2i5p:P
47 1nbo:O 337 333 0.4471 0.4510 0.4565 1.94e-78 1jn0:O, 1jn0:A, 1jn0:B, 1nbo:A, 1nbo:B, 2pkq:P, 2pkq:R, 2pkq:S, 2pkr:O, 2pkr:R, 2pkr:P, 2pkr:Q, 2pkr:A, 2pkr:B, 2pkr:C, 2pkr:D, 2pkr:H, 2pkr:I, 2pkr:L, 2pkr:M, 7q53:P, 7q53:R, 7q54:R, 7q54:P, 7q54:B, 7q54:D, 7q55:P, 7q55:R, 7q55:B, 7q55:D, 7q55:F, 7q55:H, 7q55:J, 7q55:L, 7q56:J, 7q56:L, 7q56:B, 7q56:D, 7q56:R, 7q56:P, 7q56:H, 7q56:F, 7q57:P, 7q57:R, 7q57:B, 7q57:D, 7q57:H, 7q57:F, 7q57:J, 7q57:L, 7q57:N, 7q57:T, 1rm3:O, 1rm3:A, 1rm3:B, 1rm4:O, 1rm4:A, 1rm4:B, 1rm5:O, 1rm5:A, 1rm5:B
48 3h9e:P 337 337 0.4235 0.4273 0.4273 1.97e-78 5c7o:O, 5c7o:P, 3h9e:O, 3pfw:O, 3pfw:P
49 1cer:O 331 331 0.4235 0.4350 0.4350 6.27e-78 1cer:P, 1cer:Q, 1cer:R, 1cer:A, 1cer:B, 1cer:C, 1cer:D, 2g82:O, 2g82:P, 2g82:Q, 2g82:R, 2g82:A, 2g82:B, 2g82:C, 2g82:D, 1vc2:A
50 2vyn:D 334 339 0.4147 0.4222 0.4159 7.40e-78 2vyv:D
51 3b1j:A 338 335 0.4412 0.4438 0.4478 9.30e-78 3b1j:B, 3b1k:A, 3b1k:H, 3b1k:B, 3b1k:G, 3b20:A, 3b20:B, 3b20:O, 3b20:P, 3b20:Q, 3b20:R, 2d2i:A, 2d2i:B, 2d2i:O, 2d2i:P, 2d2i:Q, 2d2i:R, 2duu:A, 2duu:B, 2duu:O, 2duu:P, 2duu:Q, 2duu:R
52 2xf8:M 327 342 0.3941 0.4098 0.3918 1.10e-71 2xf8:A, 2xf8:C, 2xf8:E, 2xf8:G, 2xf8:I, 2xf8:K, 2xf8:O
53 3k2b:A 337 332 0.4206 0.4243 0.4307 1.04e-70 3k2b:B, 3k2b:C, 3k2b:D, 3k2b:E, 3k2b:F, 3k2b:G, 3k2b:H, 3k2b:O, 3k2b:Q, 6kez:A, 6kez:B, 6kez:C, 6kez:D, 6kez:E, 6kez:F, 6kez:G, 6kez:H, 3qv1:A, 3qv1:D, 3qv1:B, 3qv1:C, 3qv1:F, 3qv1:E, 3rvd:A, 3rvd:D, 3rvd:B, 3rvd:C, 3rvd:O, 3rvd:Q, 3rvd:F, 3rvd:G, 3rvd:E, 3rvd:H
54 7zq3:R 348 333 0.4235 0.4138 0.4324 1.58e-66 7zq3:O, 7zq4:O, 7zq4:R, 7zqk:O, 7zqk:R
55 7q54:C 368 335 0.4294 0.3967 0.4358 9.33e-66 2pkq:O, 2pkq:Q, 2pkq:T, 7q53:O, 7q53:Q, 7q54:Q, 7q54:O, 7q54:A, 7q55:O, 7q55:Q, 7q55:A, 7q55:C, 7q55:E, 7q55:G, 7q55:I, 7q55:K, 7q56:K, 7q56:E, 7q56:I, 7q56:A, 7q56:G, 7q56:C, 7q56:Q, 7q56:O, 7q57:O, 7q57:Q, 7q57:A, 7q57:C, 7q57:G, 7q57:E, 7q57:I, 7q57:K, 7q57:M, 7q57:S
56 9iil:A 341 339 0.3824 0.3812 0.3835 7.14e-65 9iil:B, 9iil:C, 9iil:D, 9iim:A, 9iim:C, 9iim:B, 9iim:D, 9ij6:A, 9ij6:C, 9ij6:B, 9ij6:D, 8zn1:A, 8zn1:C, 8zn1:B, 8zn1:D, 8zn4:A, 8zn4:B, 8zn4:C, 8zn4:D, 8zoz:A, 8zoz:C, 8zoz:B, 8zoz:D
57 8jb1:A 468 349 0.3735 0.2714 0.3639 2.32e-51 8jb1:B
58 4l8v:A 337 72 0.0706 0.0712 0.3333 0.097 4l8v:B, 4l8v:C, 4l8v:D, 3nt2:A, 3nt2:B, 3nt4:A, 3nt4:B, 3nt5:A, 3nt5:B, 3ntq:A, 3ntq:B, 3ntr:A, 3ntr:B
59 3ec7:A 336 51 0.0618 0.0625 0.4118 0.47 3ec7:B, 3ec7:C, 3ec7:D, 3ec7:E, 3ec7:F, 3ec7:G, 3ec7:H
60 2czc:A 334 50 0.0529 0.0539 0.3600 0.94 2czc:B, 2czc:C, 2czc:D
61 3dc2:A 526 44 0.0529 0.0342 0.4091 2.3 3dc2:B, 3ddn:B
62 2hq9:B 138 42 0.0412 0.1014 0.3333 2.4 2hq9:A
63 8bx8:A 4453 59 0.0529 0.0040 0.3051 3.0 7k58:A, 7k5b:A, 7kek:A
64 5odj:A 179 76 0.0618 0.1173 0.2763 3.2 5odl:A
65 2hzl:B 337 52 0.0441 0.0445 0.2885 4.0 2hzl:A
66 8xld:A 213 122 0.0882 0.1408 0.2459 4.0 8ill:B
67 1cdo:A 374 25 0.0353 0.0321 0.4800 4.8 1cdo:B
68 7f79:C 458 149 0.1147 0.0852 0.2617 5.6 7f79:A, 7f79:B, 7f79:D, 7f79:E, 7f79:F
69 8bwy:C 4264 59 0.0529 0.0042 0.3051 8.7
70 7moq:C 4159 59 0.0529 0.0043 0.3051 9.2 6zyy:C
71 7qiw:a 132 40 0.0471 0.1212 0.4000 9.7 8azw:m, 8b2l:m3, 7qiz:a
72 6zyw:C 4433 59 0.0529 0.0041 0.3051 9.8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218