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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MSSTPSNQNIIPIIKKESIVSLFEKGIRQDGRKLTDYRPLSITLDYAKKADGSALVKLGTTMVLAGTKLEIDKPYEDTPN
QGNLIVNVELLPLAYETFEPGPPDENAIELARVVDRSLRDSKALDLTKLVIEPGKSVWTVWLDVYVLDYGGNVLDACTLA
SVAALYNTKVYKVEQISVNKNEVVGKLPLNYPVVTISVAKVDKYLVVDPDLDEESIMDAKISFSYTPDLKIVGIQKSGKG
SMSLQDIDQAENTARSTAVKLLEELKKHLG

The query sequence (length=270) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4ba2:A 274 271 1.0000 0.9854 0.9963 0.0 2c37:I, 2c37:U, 2c38:G, 2c38:I, 2c38:U, 2c38:W, 2jea:A
2 2pnz:B 267 258 0.4519 0.4569 0.4729 1.95e-66
3 3m85:I 259 261 0.4222 0.4402 0.4368 4.63e-55 3m7n:I, 3m7n:G, 3m7n:H, 3m85:G, 3m85:H
4 6d6q:C 265 260 0.3074 0.3132 0.3192 6.50e-42 6d6r:C
5 6d6q:A 287 263 0.2963 0.2787 0.3042 1.10e-28 6d6r:A
6 4ifd:A 300 241 0.2667 0.2400 0.2988 9.67e-25 6fsz:AA
7 3m7n:E 248 250 0.2148 0.2339 0.2320 1.30e-13 3m7n:F, 3m7n:D, 3m85:F, 3m85:D, 3m85:E
8 3dd6:A 244 251 0.2370 0.2623 0.2550 3.97e-11
9 1r6m:A 236 219 0.2333 0.2669 0.2877 3.68e-10
10 2c39:D 248 236 0.2000 0.2177 0.2288 1.22e-08 4ba1:B, 4ba2:B, 2c37:B, 2c37:F, 2c37:N, 2c37:V, 2c37:X, 2c38:B, 2c38:F, 2c38:H, 2c38:J, 2c38:N, 2c38:V, 2c38:X, 2c39:B, 2c39:F, 2c39:H, 2c39:J, 2c39:L, 2c39:N, 2c39:P, 2c39:R, 2c39:T, 2c39:V, 2c39:X, 2jea:B
11 2wnr:B 222 249 0.2111 0.2568 0.2289 2.57e-08 2wnr:D, 2wnr:F
12 2pnz:A 236 206 0.1704 0.1949 0.2233 3.68e-08 2po0:A, 2po1:A, 2po2:A
13 8wx0:A 597 47 0.0741 0.0335 0.4255 0.007 8wx0:B, 8wx0:C
14 7ld5:A 587 47 0.0741 0.0341 0.4255 0.012 7ld5:B, 7ld5:C
15 4oo1:E 255 206 0.1630 0.1725 0.2136 0.020
16 6d6q:B 241 214 0.1778 0.1992 0.2243 0.047 6d6r:B
17 5yjj:A 442 53 0.0704 0.0430 0.3585 0.072 5yjj:B, 5yjj:C, 5yjj:D, 5yjj:E, 5yjj:F
18 1e3p:A 645 44 0.0630 0.0264 0.3864 0.15
19 1e3p:A 645 83 0.1111 0.0465 0.3614 8.1
20 4aim:A 698 179 0.1741 0.0673 0.2626 0.97 4aid:A, 4aid:B, 4aid:C, 4am3:A, 4am3:C, 4am3:B
21 4aim:A 698 105 0.0963 0.0372 0.2476 7.7 4aid:A, 4aid:B, 4aid:C, 4am3:A, 4am3:C, 4am3:B
22 6ogz:A 1082 94 0.1037 0.0259 0.2979 4.7 6ogy:A, 6oj6:P, 2r7r:A, 2r7s:A, 2r7t:A, 2r7u:A, 2r7v:A, 2r7w:A, 2r7x:A, 2r7x:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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